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The map label for this gene is rarA [H]

Identifier: 37679508

GI number: 37679508

Start: 1351662

End: 1353011

Strand: Direct

Name: rarA [H]

Synonym: VV1324

Alternate gene names: 37679508

Gene position: 1351662-1353011 (Clockwise)

Preceding gene: 37679507

Following gene: 161486631

Centisome position: 40.29

GC content: 49.04

Gene sequence:

>1350_bases
GTGTCAAATTACACCTTAGATTTTTCAGGGGACGAAGATTTTCGTCCCCTTGCTGCTCGTATGAGACCGGAAACGATCGA
ACAGTACATCGGTCAGCAGCATATTTTAGGTCCTGGTAAGCCATTACGTCGCGCGCTAGAGGCCGGCCACATTCATTCAA
TGATTTTGTGGGGGCCTCCAGGTACAGGCAAGACAACATTAGCGGAAGTAGCCGCAAACTACGCCAACGCGGAAGTTGAA
CGCGTCTCTGCGGTCACGTCCGGCGTGAAAGAAATTCGTGCCGCAATTGAAAAAGCACGCGAGAACAAAATGGCGGGTCG
TCGCACCATCTTGTTTGTGGATGAGGTACATCGCTTTAATAAATCACAGCAAGATGCCTTCTTACCGCACATTGAAGATG
GAACAGTGACTTTTATCGGCGCGACCACAGAAAATCCATCGTTTGAACTGAACAACGCATTATTGTCACGTGCTCGTGTG
TATAAGCTTACGTCACTCAACAAAGAAGAAATCTCACTGGCATTAAACCAAGCGATCAACGATAAACAACGTGGTCTGGG
TAATACACCAGCACACTTTGCTGATAATGTCTTGGATCGTCTGGCTGAGCTCGTCAATGGTGATGCGCGAATGTCTCTTA
ACTATCTTGAGCTGCTGTATGACATGGCAGAAGACAATGCTCAGGGTGAAAAAGCGATCACGCTAAAGCTATTGGCGGAA
GTGGCGGGGGAGAAGGTCTCTCGTTTTGATAATAAAGGCGACATTTGGTACGACTTAATCTCTGCCGTGCACAAATCCAT
CCGTGGTTCCAATCCGGATGCTGCGCTTTATTGGGCGGCGAGAATGATCGCTGCCGGTTGTGATCCACTCTATATCGCGC
GACGTTTGCTGGCCATTGCCTCTGAAGATGTGGGCAATGCGGATCCGAGGGCAATGCAAGTGGCACTTTCCGCGTGGGAT
TGCTTTACCCGTGTTGGACCCGCAGAAGGCGAACGCGCAATTGCACAGGCGATCGTTTACCTTGCGTGCGCACCGAAAAG
TAATGCGGTTTACACCGCTTGGAAGCAAGCGCTGTCGGATGCGCATAATCTTCCAGAGTTTGAAGTGCCTTTCCATTTGC
GTAATGCACCGACCGGATTGATGAAAGATCTCGGTTATGGGGAAGGTTATCGATACGCTCATGATGAACCAGGGGCCTAC
GCCGCGGGCGAACAATATTTTCCTGCTGAAATTGCTGATCGCAAGTACTATCAGCCAACAAATCGAGGCTTAGAGAGCAA
AATCGCTGAAAAGTTAGATTACTTGGCTAATTTAGACGCAAATAGCCCACAAAAGCGCTATGAAAAGTAG

Upstream 100 bases:

>100_bases
CAAGTTTACGGATATGAAGCTAGGAAAGCCTGCAGCTGCCCGCTTCACCTTTAACATCCCTGAAGGGGTTGAAGTGGATG
ACCAAAGGAACTAATCGCCA

Downstream 100 bases:

>100_bases
GCATTTTTGGATACATTTGTTCGGTTAATTTTTTCAACGTGCTCGACAGGATTGGGTGCGTACCTTCACAACAAAAAGCA
TAGGATTAACAATGCTGGAT

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSNYTLDFSGDEDFRPLAARMRPETIEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKMAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNKEEISLALNQAINDKQRGLGNTPAHFADNVLDRLAELVNGDARMSLNYLELLYDMAEDNAQGEKAITLKLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSNPDAALYWAARMIAAGCDPLYIARRLLAIASEDVGNADPRAMQVALSAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPFHLRNAPTGLMKDLGYGEGYRYAHDEPGAY
AAGEQYFPAEIADRKYYQPTNRGLESKIAEKLDYLANLDANSPQKRYEK

Sequences:

>Translated_449_residues
MSNYTLDFSGDEDFRPLAARMRPETIEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKMAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNKEEISLALNQAINDKQRGLGNTPAHFADNVLDRLAELVNGDARMSLNYLELLYDMAEDNAQGEKAITLKLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSNPDAALYWAARMIAAGCDPLYIARRLLAIASEDVGNADPRAMQVALSAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPFHLRNAPTGLMKDLGYGEGYRYAHDEPGAY
AAGEQYFPAEIADRKYYQPTNRGLESKIAEKLDYLANLDANSPQKRYEK
>Mature_448_residues
SNYTLDFSGDEDFRPLAARMRPETIEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVER
VSAVTSGVKEIRAAIEKARENKMAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVY
KLTSLNKEEISLALNQAINDKQRGLGNTPAHFADNVLDRLAELVNGDARMSLNYLELLYDMAEDNAQGEKAITLKLLAEV
AGEKVSRFDNKGDIWYDLISAVHKSIRGSNPDAALYWAARMIAAGCDPLYIARRLLAIASEDVGNADPRAMQVALSAWDC
FTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPFHLRNAPTGLMKDLGYGEGYRYAHDEPGAYA
AGEQYFPAEIADRKYYQPTNRGLESKIAEKLDYLANLDANSPQKRYEK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=441, Percent_Identity=43.0839002267574, Blast_Score=318, Evalue=9e-87,
Organism=Homo sapiens, GI18426904, Length=441, Percent_Identity=38.7755102040816, Blast_Score=259, Evalue=3e-69,
Organism=Escherichia coli, GI1787119, Length=447, Percent_Identity=73.6017897091723, Blast_Score=675, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324111, Length=429, Percent_Identity=40.3263403263403, Blast_Score=321, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6324039, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 49694; Mature: 49563

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYTLDFSGDEDFRPLAARMRPETIEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCCEEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKMAGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNKEEISLALNQAIN
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DKQRGLGNTPAHFADNVLDRLAELVNGDARMSLNYLELLYDMAEDNAQGEKAITLKLLAE
HHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSNPDAALYWAARMIAAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
SEDVGNADPRAMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPFHLRNAPTGLMKDLGYGEGYRYAHDEPGAYAAGEQYFPAEIADRKYYQPT
HHCCCCCCCCEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC
NRGLESKIAEKLDYLANLDANSPQKRYEK
CCCHHHHHHHHHHHHHCCCCCCCHHHCCC
>Mature Secondary Structure 
SNYTLDFSGDEDFRPLAARMRPETIEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCEEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKMAGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNKEEISLALNQAIN
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
DKQRGLGNTPAHFADNVLDRLAELVNGDARMSLNYLELLYDMAEDNAQGEKAITLKLLAE
HHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSNPDAALYWAARMIAAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
SEDVGNADPRAMQVALSAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPFHLRNAPTGLMKDLGYGEGYRYAHDEPGAYAAGEQYFPAEIADRKYYQPT
HHCCCCCCCCEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC
NRGLESKIAEKLDYLANLDANSPQKRYEK
CCCHHHHHHHHHHHHHCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]