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The map label for this gene is sohB [H]

Identifier: 37679482

GI number: 37679482

Start: 1319659

End: 1320720

Strand: Direct

Name: sohB [H]

Synonym: VV1298

Alternate gene names: 37679482

Gene position: 1319659-1320720 (Clockwise)

Preceding gene: 37679478

Following gene: 37679483

Centisome position: 39.34

GC content: 43.6

Gene sequence:

>1062_bases
TTGGAATTTTTATTAGATTACGGCTTGTTTTTAGCGAAAGTCGTTACCTTTATTGTGGCCGTTGTCGTGTTACTCATACT
GGCCAAATCTGTGAGTGGAAAATCTTCCGCAATCAAAGGCGAGTTAGAAATTACGGACTTGTCGGAGTTGCACAAGAGCA
ATGTTGAACACTTAGAGCATTATCTTCACGATGAGGCTTATCTCAAAGCACGTCATAAAGCGGAGAAAAAGGAAGAAAAA
GAAAAAGATAAGCTGCGTGAAAAAGAGATAAAAAAAGCCGCCAAAGAAGGTAAGTTGGATCACAAGCGTGAACCGCATCT
GTTTGTATTGGATTTCAATGGCAGTATCGACGCGAAAGAAGTGAAATCATTACGCGAAGAGATTACCGCCATTCTAGCCG
TTGCAGGGGAAGGCGATGAAGTATTGCTGCGTTTAGAATCTGGCGGCGGCATGGTTCACGGTTATGGTTTGGCCTCGTCA
CAATTGGATCGTATTAAAGCCGCGGGATTACCGCTCACGATTGCAGTTGATAAAGTGGCGGCCAGTGGTGGCTACATGAT
GGCTTGTGTTGCGGATAAAATTGTTTCTGCTCCATTTGCCATCGTTGGTTCAATCGGTGTCATTGCCCAGATCCCAAACT
TCAACAAGCTATTAAAGAAGCATGATATTGAGTTTGAACAAATGACCGCTGGTGAATACAAACGCACCTTAACCATGTTT
GGTGAAAATACCGACAAAGCTCGTGAGAAATTTAAGCAAGAATTGGAAGAAACGCATGATCTGTTTAAAGATTTTATTCG
TGAGCGTCGTCCTGAATTAGAGCTTGAAAAAGTCGCAACAGGGGAGCACTGGTTTGGAACGCAGGCCCATGCGTTAGGAT
TAGTGGATGACATTGCGACTTCTGATGATCTTATTGTTGCGGCATGCAAAGAAAAAACCGTGCTGGCAGTACATTATGTA
CAAAAGAAAAAACTGGCAGATAAACTAGCCGGTAGCGCGGCAAAAGTGGCAGACAGTGTGATTCTTAAACTGGCTGAGCG
TGGACAAAAGCCCATCGTTTAA

Upstream 100 bases:

>100_bases
TATCCTGCGTTGCAAAATCAAACAGATATGCAACGGAAAGTCTTGGTAATCGTGACAAGATGGTTACAATACACCAATTC
ACACTCTAGGGGATATTACA

Downstream 100 bases:

>100_bases
TGCGTACGCACAGGCAATCATCATTACGGCGAAGGTTCTTACTTTCGCCGTTTTTCATTGTGGTCAATAAGATCGTCGAT
GTAATCGATTACTTAGGGAT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEFLLDYGLFLAKVVTFIVAVVVLLILAKSVSGKSSAIKGELEITDLSELHKSNVEHLEHYLHDEAYLKARHKAEKKEEK
EKDKLREKEIKKAAKEGKLDHKREPHLFVLDFNGSIDAKEVKSLREEITAILAVAGEGDEVLLRLESGGGMVHGYGLASS
QLDRIKAAGLPLTIAVDKVAASGGYMMACVADKIVSAPFAIVGSIGVIAQIPNFNKLLKKHDIEFEQMTAGEYKRTLTMF
GENTDKAREKFKQELEETHDLFKDFIRERRPELELEKVATGEHWFGTQAHALGLVDDIATSDDLIVAACKEKTVLAVHYV
QKKKLADKLAGSAAKVADSVILKLAERGQKPIV

Sequences:

>Translated_353_residues
MEFLLDYGLFLAKVVTFIVAVVVLLILAKSVSGKSSAIKGELEITDLSELHKSNVEHLEHYLHDEAYLKARHKAEKKEEK
EKDKLREKEIKKAAKEGKLDHKREPHLFVLDFNGSIDAKEVKSLREEITAILAVAGEGDEVLLRLESGGGMVHGYGLASS
QLDRIKAAGLPLTIAVDKVAASGGYMMACVADKIVSAPFAIVGSIGVIAQIPNFNKLLKKHDIEFEQMTAGEYKRTLTMF
GENTDKAREKFKQELEETHDLFKDFIRERRPELELEKVATGEHWFGTQAHALGLVDDIATSDDLIVAACKEKTVLAVHYV
QKKKLADKLAGSAAKVADSVILKLAERGQKPIV
>Mature_353_residues
MEFLLDYGLFLAKVVTFIVAVVVLLILAKSVSGKSSAIKGELEITDLSELHKSNVEHLEHYLHDEAYLKARHKAEKKEEK
EKDKLREKEIKKAAKEGKLDHKREPHLFVLDFNGSIDAKEVKSLREEITAILAVAGEGDEVLLRLESGGGMVHGYGLASS
QLDRIKAAGLPLTIAVDKVAASGGYMMACVADKIVSAPFAIVGSIGVIAQIPNFNKLLKKHDIEFEQMTAGEYKRTLTMF
GENTDKAREKFKQELEETHDLFKDFIRERRPELELEKVATGEHWFGTQAHALGLVDDIATSDDLIVAACKEKTVLAVHYV
QKKKLADKLAGSAAKVADSVILKLAERGQKPIV

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=353, Percent_Identity=54.3909348441926, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1788064, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 39009; Mature: 39009

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLLDYGLFLAKVVTFIVAVVVLLILAKSVSGKSSAIKGELEITDLSELHKSNVEHLEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCHHHHHH
YLHDEAYLKARHKAEKKEEKEKDKLREKEIKKAAKEGKLDHKREPHLFVLDFNGSIDAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHH
VKSLREEITAILAVAGEGDEVLLRLESGGGMVHGYGLASSQLDRIKAAGLPLTIAVDKVA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHH
ASGGYMMACVADKIVSAPFAIVGSIGVIAQIPNFNKLLKKHDIEFEQMTAGEYKRTLTMF
CCCCEEHHHHHHHHHHCCHHHHHCCHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
GENTDKAREKFKQELEETHDLFKDFIRERRPELELEKVATGEHWFGTQAHALGLVDDIAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
SDDLIVAACKEKTVLAVHYVQKKKLADKLAGSAAKVADSVILKLAERGQKPIV
CCCEEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEFLLDYGLFLAKVVTFIVAVVVLLILAKSVSGKSSAIKGELEITDLSELHKSNVEHLEH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCHHHHHH
YLHDEAYLKARHKAEKKEEKEKDKLREKEIKKAAKEGKLDHKREPHLFVLDFNGSIDAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHH
VKSLREEITAILAVAGEGDEVLLRLESGGGMVHGYGLASSQLDRIKAAGLPLTIAVDKVA
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHCCCCEEEEEHHHH
ASGGYMMACVADKIVSAPFAIVGSIGVIAQIPNFNKLLKKHDIEFEQMTAGEYKRTLTMF
CCCCEEHHHHHHHHHHCCHHHHHCCHHEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
GENTDKAREKFKQELEETHDLFKDFIRERRPELELEKVATGEHWFGTQAHALGLVDDIAT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCC
SDDLIVAACKEKTVLAVHYVQKKKLADKLAGSAAKVADSVILKLAERGQKPIV
CCCEEEEECCCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]