Click here to switch to the map view.

The map label for this gene is udk [H]

Identifier: 37679445

GI number: 37679445

Start: 1280613

End: 1281263

Strand: Direct

Name: udk [H]

Synonym: VV1261

Alternate gene names: 37679445

Gene position: 1280613-1281263 (Clockwise)

Preceding gene: 37679444

Following gene: 37679446

Centisome position: 38.18

GC content: 45.01

Gene sequence:

>651_bases
GTGCAACTAATGTCTGAAAAAAGTCAATGCGTCATCGTCGGTATTGCTGGCGCTTCTGCTTCTGGTAAAAGCCTCATCGC
CAGTACGATTTATAACGAACTACGTGCAAAGGTGGGAGACCATCAAATCGGTGTGATTACGGAAGATTGCTACTATAACG
ACCAAAGCCATCTGAGTATGGAAGAGCGCGTTAAAACGAACTATGACCACCCAAATGCACTTGATCACGATCTTCTTTGT
GAACACTTAGAAAAGTTAATGAAAGGCGAGTCGGTTGAAGTACCTGAATACAGCTACACGGAGCACACTCGTACTGAAAA
CACCACCACTATGACACCAAAGAAGGTGATCATTCTTGAAGGCATCCTGCTTCTGACGGATCCTCGTCTGCGTGATTTGA
TGCATGCGACAGTGTTTATGGACACGCCACTGGATATCTGTCTACTTCGCCGTGTGAAACGCGATGTGGAAGAGCGTGGT
CGTACGATGGAATCGGTACTCAAACAGTATCAAAAAACAGTTCGCCCAATGTTTATGCAGTTTATTGAACCGTCTAAACA
GTACGCAGATATCATCGTTCCTCGTGGTGGTAAAAACCGCATCGCGATTGACGTACTGAAAGCGCACATTGCAAAACTAT
TGAAAGCTTAA

Upstream 100 bases:

>100_bases
CAATGCACCACGAAACTGGGAAAAGCGACTAGTATCTAATGAGTGAACTCCTTATAATCAGGCGGTTTATCTTATTCCCA
CTGCAAAAAATCATCATCGG

Downstream 100 bases:

>100_bases
GTCATTGTCTTGTCAGCGAGCTTTATTTTTAATTAAGAAAGTGGCACTTTAGATGCCACTTTCTTTTTTTGCAGCAAGAA
CCGCGTAAAATACGTGTTTT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MQLMSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSMEERVKTNYDHPNALDHDLLC
EHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERG
RTMESVLKQYQKTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA

Sequences:

>Translated_216_residues
MQLMSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSMEERVKTNYDHPNALDHDLLC
EHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERG
RTMESVLKQYQKTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA
>Mature_216_residues
MQLMSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSMEERVKTNYDHPNALDHDLLC
EHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILEGILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERG
RTMESVLKQYQKTVRPMFMQFIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI301129207, Length=208, Percent_Identity=38.9423076923077, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI57863312, Length=208, Percent_Identity=38.9423076923077, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI18699734, Length=213, Percent_Identity=37.0892018779343, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI13899253, Length=215, Percent_Identity=37.2093023255814, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI209863022, Length=153, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=5e-21,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=73.2394366197183, Blast_Score=337, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17539894, Length=205, Percent_Identity=38.5365853658537, Blast_Score=156, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17539892, Length=205, Percent_Identity=38.5365853658537, Blast_Score=156, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI71981181, Length=214, Percent_Identity=34.1121495327103, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=32.7683615819209, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24649624, Length=212, Percent_Identity=39.1509433962264, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI221458995, Length=214, Percent_Identity=38.785046728972, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI28573516, Length=208, Percent_Identity=38.9423076923077, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI28573514, Length=208, Percent_Identity=38.9423076923077, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI28573512, Length=208, Percent_Identity=38.9423076923077, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI45550449, Length=208, Percent_Identity=38.9423076923077, Blast_Score=160, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24618; Mature: 24618

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLMSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSM
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHCCH
EERVKTNYDHPNALDHDLLCEHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILE
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHH
GILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERGRTMESVLKQYQKTVRPMFMQ
CHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA
HHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLMSEKSQCVIVGIAGASASGKSLIASTIYNELRAKVGDHQIGVITEDCYYNDQSHLSM
CCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCEECCHHHCCH
EERVKTNYDHPNALDHDLLCEHLEKLMKGESVEVPEYSYTEHTRTENTTTMTPKKVIILE
HHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHH
GILLLTDPRLRDLMHATVFMDTPLDICLLRRVKRDVEERGRTMESVLKQYQKTVRPMFMQ
CHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
FIEPSKQYADIIVPRGGKNRIAIDVLKAHIAKLLKA
HHCCCHHHHEEEECCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]