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The map label for this gene is moaC

Identifier: 37679384

GI number: 37679384

Start: 1216350

End: 1216829

Strand: Direct

Name: moaC

Synonym: VV1200

Alternate gene names: 37679384

Gene position: 1216350-1216829 (Clockwise)

Preceding gene: 37679383

Following gene: 37679385

Centisome position: 36.26

GC content: 49.17

Gene sequence:

>480_bases
ATGAGCCAGTTTACTCACATCAACGCCTCTGGCGAAGCAAACATGGTGGATGTATCTGCCAAAGCTGAAACGGTACGCGA
AGCACGTGCGGAAGCGTTTGTGCATATGGCACCAGAGACATTACAGCTTATTGTTTCTGGTCAGCATCACAAAGGGGATG
TGTTTGCCACGGCGAGAATCGCAGGCATACAAGCGGCGAAGAAAACTTGGGATTTGATCCCATTGTGTCATCCGTTATTG
CTTTCAAAAGTTGAAGTGCAGCTAGAAGCGATCGAAGCGGAGAATAAAGTGCGTATCGAATCGGTTTGTAAGCTGGCAGG
CAAAACGGGTGTAGAGATGGAAGCCTTGACGGCAGCGTCGGTCGCGGCACTGACAATTTACGATATGTGTAAAGCAGTGC
AGAAAGACATGGTGATAGGCCCCGTGCGTTTGCTAGAGAAAACGGGTGGTAAGTCTGGACACTTTAAGGTGGAAGCATGA

Upstream 100 bases:

>100_bases
GCTTGTCGTACGGGTTGGACTAAAATCATCAAGCAACAATTGGATGCGAGCCATCGTCCTTGCAACTTTATGCCTCACCT
GAGCGTATAAAGGAGAGCCC

Downstream 100 bases:

>100_bases
TTAAGGTTTTATTCTTTGCTCAAACCCGTGAGCTGGTGGGTGTGGATTCAGTCGATGTTGAGGCGAACTTCGACACCGTT
GAATCACTTCGAGCACATTT

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MSQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIPLCHPLL
LSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA

Sequences:

>Translated_159_residues
MSQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIPLCHPLL
LSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA
>Mature_158_residues
SQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARIAGIQAAKKTWDLIPLCHPLLL
SKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=159, Percent_Identity=83.0188679245283, Blast_Score=274, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=40.3973509933775, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=56.6666666666667, Blast_Score=164, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=57.6642335766423, Blast_Score=153, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17093; Mature: 16962

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARI
CCCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCCCEEEEHHH
AGIQAAKKTWDLIPLCHPLLLSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECC
>Mature Secondary Structure 
SQFTHINASGEANMVDVSAKAETVREARAEAFVHMAPETLQLIVSGQHHKGDVFATARI
CCCEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCCCEEEEHHH
AGIQAAKKTWDLIPLCHPLLLSKVEVQLEAIEAENKVRIESVCKLAGKTGVEMEALTAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHH
VAALTIYDMCKAVQKDMVIGPVRLLEKTGGKSGHFKVEA
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA