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The map label for this gene is siaT [H]

Identifier: 37679282

GI number: 37679282

Start: 1101801

End: 1103162

Strand: Direct

Name: siaT [H]

Synonym: VV1098

Alternate gene names: 37679282

Gene position: 1101801-1103162 (Clockwise)

Preceding gene: 37679281

Following gene: 37679283

Centisome position: 32.85

GC content: 49.71

Gene sequence:

>1362_bases
ATGGATATTCTATTTTTATTTTTGTTAGTCATTGGCTTTATGCTGATTGGCGTGCCTATCGCGGTTTCTCTCGGCTTATC
GAGCATTCTGTTTTTGATGTGGCACTCCGATGCGTCTTTGGCGTCGGTGGCGCAGACTTTATTTAATGCCTTTGAAGGCC
ATTACACCTTGTTGGCGATTCCGTTTTTTATCTTGGCATCCAGTTTTATGTCGACGGGTGGGGTAGCCAAGCGCATCATT
CGATTTGCGATTGCCATGGTAGGTTGGTTTCGCGGTGGCCTTGCCATGGCCTCGGTGGTGGCATGTATGATGTTTGCCGC
GCTGTCCGGCTCTTCTCCGGCTACCGTGGTGGCAATTGGTAGCATCGTTATCGCTGGGATGATCAAAAACGGTTACTCGA
AAGAATTCGCGGCTGGGGTGATTTGTAATGCCGGGACACTGGGTATTTTGATCCCACCGTCGATTGTGATGGTCGTTTAC
TCTGCGGCCACCGATGTCTCGGTCGGTCGTATGTTCCTTGGTGGCGTGATCCCAGGGCTACTTGCCGGTCTTATGCTGAT
TGTGGCGATTTATATTGCAGCACGAATAAAAAATCTGCCTAAGCAGCCTTTTGTGGGTTGGTCAGAAGCCATCAACGCGG
CAAAGGAAGCGAGTTGGGGATTGCTGTTGGTGGTGATCATCCTTGGTGGTATCTATGGGGGCATTTTTACCCCAACCGAA
GCGGCTGCGGTGGCTGCCGTCTACTCATTCTTGATCGCTAACTTCGTTTATAAAGACATGGGGCCTTTTGCCGATAAGCA
AAACCAACGTCCTGCGCTCGTGAAAGTGTTTGAAGCCTTCTTTCATAAAGACACCCAACATACGCTTTTTGAAGCGGGTA
AGCTGACCATCATGTTGTTGTTTATCATTGCCAACGCATTGATTCTTAAACACGTACTGACGGAAGAGCGCATTCCGCAA
ATGATCACAGAATCGATGTTGTCAGCGGGGCTTGGTCCCATCACCTTCTTGATTGTGGTTAACGTATTGCTGCTGATTGG
CGGTCAGTTTATGGAACCCTCAGGTCTACTGATCATCGTGGCTCCGTTAGTCTTCCCCATCGCCATTGCGTTAGGCATCG
ACCCGATTCACTTGGGTATCATCATGGTGGTGAACATGGAAATCGGCATGATCACACCGCCTGTCGGGCTCAATTTATTC
GTCACCGCAGGGGTGGCAAAAATGTCGATGATGAACGTGGTCAAAGCCGCATTGCCTTGGGTGGCGGTGATGTTCCTCTT
CCTCATTATTGTCACGTACGTTCCTTGGGTATCGACTTGGCTACCAACCACACTGATGGGGCCGGAGATCATTACCAAGT
AA

Upstream 100 bases:

>100_bases
CCATGAGGCAGAAGAAGATCTTGAAGCATTGAAAGCGGAGATGGGTGATGCCGACGATTTGATGGGTGGTTCACGTCGTG
ATGGTAAGGAGCAGTAAGCG

Downstream 100 bases:

>100_bases
CCATGTCGCCTTACCGCAGATTCAATGCGATAAGGTCAAGTGGTAAGTCTCTGTAATAAGTACGAAATTCGTTAAACGTA
ACCCGCCAACGCCCATTTGG

Product: TRAP-type C4-dicarboxylate transport system, large permease component

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDILFLFLLVIGFMLIGVPIAVSLGLSSILFLMWHSDASLASVAQTLFNAFEGHYTLLAIPFFILASSFMSTGGVAKRII
RFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYSKEFAAGVICNAGTLGILIPPSIVMVVY
SAATDVSVGRMFLGGVIPGLLAGLMLIVAIYIAARIKNLPKQPFVGWSEAINAAKEASWGLLLVVIILGGIYGGIFTPTE
AAAVAAVYSFLIANFVYKDMGPFADKQNQRPALVKVFEAFFHKDTQHTLFEAGKLTIMLLFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIIMVVNMEIGMITPPVGLNLF
VTAGVAKMSMMNVVKAALPWVAVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK

Sequences:

>Translated_453_residues
MDILFLFLLVIGFMLIGVPIAVSLGLSSILFLMWHSDASLASVAQTLFNAFEGHYTLLAIPFFILASSFMSTGGVAKRII
RFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYSKEFAAGVICNAGTLGILIPPSIVMVVY
SAATDVSVGRMFLGGVIPGLLAGLMLIVAIYIAARIKNLPKQPFVGWSEAINAAKEASWGLLLVVIILGGIYGGIFTPTE
AAAVAAVYSFLIANFVYKDMGPFADKQNQRPALVKVFEAFFHKDTQHTLFEAGKLTIMLLFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIIMVVNMEIGMITPPVGLNLF
VTAGVAKMSMMNVVKAALPWVAVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK
>Mature_453_residues
MDILFLFLLVIGFMLIGVPIAVSLGLSSILFLMWHSDASLASVAQTLFNAFEGHYTLLAIPFFILASSFMSTGGVAKRII
RFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYSKEFAAGVICNAGTLGILIPPSIVMVVY
SAATDVSVGRMFLGGVIPGLLAGLMLIVAIYIAARIKNLPKQPFVGWSEAINAAKEASWGLLLVVIILGGIYGGIFTPTE
AAAVAAVYSFLIANFVYKDMGPFADKQNQRPALVKVFEAFFHKDTQHTLFEAGKLTIMLLFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIIMVVNMEIGMITPPVGLNLF
VTAGVAKMSMMNVVKAALPWVAVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=419, Percent_Identity=33.1742243436754, Blast_Score=205, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48286; Mature: 48286

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILFLFLLVIGFMLIGVPIAVSLGLSSILFLMWHSDASLASVAQTLFNAFEGHYTLLAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
PFFILASSFMSTGGVAKRIIRFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIAGMIKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYSAATDVSVGRMFLGGVIPGL
HHHHHHHHHCCCCHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LAGLMLIVAIYIAARIKNLPKQPFVGWSEAINAAKEASWGLLLVVIILGGIYGGIFTPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHH
AAAVAAVYSFLIANFVYKDMGPFADKQNQRPALVKVFEAFFHKDTQHTLFEAGKLTIMLL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FIIANALILKHVLTEERIPQMITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEH
APLVFPIAIALGIDPIHLGIIMVVNMEIGMITPPVGLNLFVTAGVAKMSMMNVVKAALPW
HHHHHHHHHHHCCCHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCC
>Mature Secondary Structure
MDILFLFLLVIGFMLIGVPIAVSLGLSSILFLMWHSDASLASVAQTLFNAFEGHYTLLAI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
PFFILASSFMSTGGVAKRIIRFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
SIVIAGMIKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYSAATDVSVGRMFLGGVIPGL
HHHHHHHHHCCCCHHHHHHHEECCCCEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LAGLMLIVAIYIAARIKNLPKQPFVGWSEAINAAKEASWGLLLVVIILGGIYGGIFTPTE
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHH
AAAVAAVYSFLIANFVYKDMGPFADKQNQRPALVKVFEAFFHKDTQHTLFEAGKLTIMLL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FIIANALILKHVLTEERIPQMITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEH
APLVFPIAIALGIDPIHLGIIMVVNMEIGMITPPVGLNLFVTAGVAKMSMMNVVKAALPW
HHHHHHHHHHHCCCHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK
HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]