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The map label for this gene is yeiJ [C]

Identifier: 37679245

GI number: 37679245

Start: 1062936

End: 1064135

Strand: Direct

Name: yeiJ [C]

Synonym: VV1061

Alternate gene names: 37679245

Gene position: 1062936-1064135 (Clockwise)

Preceding gene: 37679244

Following gene: 37679246

Centisome position: 31.69

GC content: 49.08

Gene sequence:

>1200_bases
ATGAACTCACTCTTGGGTGTCGTAGCCATTTTGCTTTTTGCTTGGCTGCTTTCTACCAATAGAAAAAATATCCGTCTTAA
AACGGTGGGATTGGCGTTTGCATTGCAAGTGGCCTTTGCGTTGTTGGTGCTGTATGTACCTGCGGGTAAAAATGCGCTAA
ATGGCGTGACGGGCGCGGTTTCAAATTTGATTAACTATGGACAGGAAGGCATCGCTTTTCTGTTCGGCGGTTTGGCAACC
GGCGGTTTTACTTTCGCGATTAACGTTCTTGGTATCATCATCTTCTTCTCTGCCTTGATCTCAGGCCTTTACCATATTGG
ATTGATGCCGAAAGTAATCAACTTGATTGGTGGCGCCCTACAAAAGTTGTTAGGGACTGGCCGTGCTGAATCGCTTTCTG
CAACCGCCAACATCTTCGTTGGCATGATTGAAGCCCCGTTGGTGGTGAAACCTTACTTAAAGCACATGAGTGACTCGCAA
TTCTTTGCCGTCATGACCTGTGGCCTTGCTTCGGTAGCAGGCGGTACCTTAGTCGGTTACGCCTCTTTGGGGGTGGAACT
AAACTACCTGATTGCTGCGGCATTTATGTCGGCACCTGCTGGTCTTTTGATGGCCAAAATCTTGATGCCTGAAACTGAAG
CTCAGGCGGAAGATGTGCAGATGGAAAACGTTGAGATGCCAAAAGCGACCAACGTGGTGGAAGCGATGGCAGACGGTGCG
ATGTCGGGCTTGCGTATCGCGGTAGCGGTAGGGGCAACCTTACTGGCGTTTGTCAGCGTGATTGCACTGCTGAATGGCCT
GTTGGGTTGGGTCGGCAGTTGGTTTGGCATCTCTCTTAGCTTTGAGTTGATTTTGGGCTATCTATTTGCGCCAGTCGCTT
GGTTGTTGGGTATTCCATGGCATGAAGCCATTACCGCGGGTTCTCTGATCGGCAATAAGATTGTGGTGAACGAATTCGTA
GCGTTTATTCAGCTCATGCAAGTGAAACAAGATCTGAGTGCACACTCGCAAGCGATCGTGACTTTTGCTTTGTGTGGTTT
TGCTAACATCTCCACAATGGCGATGTTGATCGGTGGTTTGGGTAGCTTGGTGCCTGAAAAACGCTCGTTCATCTCGAAAT
ACGGCTTCCGTGCAATTACCGCAGGTGTCTTGGCGAACTTGATGAGCGCATCGATTGCGGGTGTGATTTTAAGCCTGTAA

Upstream 100 bases:

>100_bases
TTTCTAATGAACCACCTTGTTAACATTCTCGACTTGCATCTTACGACGCTGGTAATACAATCCGCGCCTTCCTTGTTCCC
CCTCTCTGGAAATAATCACT

Downstream 100 bases:

>100_bases
GCGATAAGAAAACAGATGACAGTCGATGCTTACGCGCTTCTGGACAAAGTGAAGCATCGTACTGTCATTATTTGTTTTTA
TACACTATCATTTTGATAAA

Product: nucleoside permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNSLLGVVAILLFAWLLSTNRKNIRLKTVGLAFALQVAFALLVLYVPAGKNALNGVTGAVSNLINYGQEGIAFLFGGLAT
GGFTFAINVLGIIIFFSALISGLYHIGLMPKVINLIGGALQKLLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQ
FFAVMTCGLASVAGGTLVGYASLGVELNYLIAAAFMSAPAGLLMAKILMPETEAQAEDVQMENVEMPKATNVVEAMADGA
MSGLRIAVAVGATLLAFVSVIALLNGLLGWVGSWFGISLSFELILGYLFAPVAWLLGIPWHEAITAGSLIGNKIVVNEFV
AFIQLMQVKQDLSAHSQAIVTFALCGFANISTMAMLIGGLGSLVPEKRSFISKYGFRAITAGVLANLMSASIAGVILSL

Sequences:

>Translated_399_residues
MNSLLGVVAILLFAWLLSTNRKNIRLKTVGLAFALQVAFALLVLYVPAGKNALNGVTGAVSNLINYGQEGIAFLFGGLAT
GGFTFAINVLGIIIFFSALISGLYHIGLMPKVINLIGGALQKLLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQ
FFAVMTCGLASVAGGTLVGYASLGVELNYLIAAAFMSAPAGLLMAKILMPETEAQAEDVQMENVEMPKATNVVEAMADGA
MSGLRIAVAVGATLLAFVSVIALLNGLLGWVGSWFGISLSFELILGYLFAPVAWLLGIPWHEAITAGSLIGNKIVVNEFV
AFIQLMQVKQDLSAHSQAIVTFALCGFANISTMAMLIGGLGSLVPEKRSFISKYGFRAITAGVLANLMSASIAGVILSL
>Mature_399_residues
MNSLLGVVAILLFAWLLSTNRKNIRLKTVGLAFALQVAFALLVLYVPAGKNALNGVTGAVSNLINYGQEGIAFLFGGLAT
GGFTFAINVLGIIIFFSALISGLYHIGLMPKVINLIGGALQKLLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQ
FFAVMTCGLASVAGGTLVGYASLGVELNYLIAAAFMSAPAGLLMAKILMPETEAQAEDVQMENVEMPKATNVVEAMADGA
MSGLRIAVAVGATLLAFVSVIALLNGLLGWVGSWFGISLSFELILGYLFAPVAWLLGIPWHEAITAGSLIGNKIVVNEFV
AFIQLMQVKQDLSAHSQAIVTFALCGFANISTMAMLIGGLGSLVPEKRSFISKYGFRAITAGVLANLMSASIAGVILSL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=409, Percent_Identity=35.4523227383863, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI42542381, Length=404, Percent_Identity=36.6336633663366, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI11545853, Length=366, Percent_Identity=36.8852459016393, Blast_Score=239, Evalue=2e-63,
Organism=Escherichia coli, GI1788485, Length=413, Percent_Identity=42.6150121065375, Blast_Score=297, Evalue=7e-82,
Organism=Escherichia coli, GI1788488, Length=415, Percent_Identity=42.4096385542169, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1788737, Length=395, Percent_Identity=32.1518987341772, Blast_Score=210, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71991794, Length=409, Percent_Identity=32.0293398533007, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI17560276, Length=395, Percent_Identity=30.379746835443, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI25146537, Length=208, Percent_Identity=30.7692307692308, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45552519, Length=399, Percent_Identity=34.8370927318296, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI45552517, Length=399, Percent_Identity=34.8370927318296, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI19921868, Length=399, Percent_Identity=34.8370927318296, Blast_Score=248, Evalue=5e-66,
Organism=Drosophila melanogaster, GI281360430, Length=398, Percent_Identity=32.4120603015075, Blast_Score=226, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 41699; Mature: 41699

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLLGVVAILLFAWLLSTNRKNIRLKTVGLAFALQVAFALLVLYVPAGKNALNGVTGAV
CCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNLINYGQEGIAFLFGGLATGGFTFAINVLGIIIFFSALISGLYHIGLMPKVINLIGGAL
HHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKLLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQFFAVMTCGLASVAGGTLVGY
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHEEH
ASLGVELNYLIAAAFMSAPAGLLMAKILMPETEAQAEDVQMENVEMPKATNVVEAMADGA
HHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHH
MSGLRIAVAVGATLLAFVSVIALLNGLLGWVGSWFGISLSFELILGYLFAPVAWLLGIPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HEAITAGSLIGNKIVVNEFVAFIQLMQVKQDLSAHSQAIVTFALCGFANISTMAMLIGGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVPEKRSFISKYGFRAITAGVLANLMSASIAGVILSL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSLLGVVAILLFAWLLSTNRKNIRLKTVGLAFALQVAFALLVLYVPAGKNALNGVTGAV
CCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SNLINYGQEGIAFLFGGLATGGFTFAINVLGIIIFFSALISGLYHIGLMPKVINLIGGAL
HHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKLLGTGRAESLSATANIFVGMIEAPLVVKPYLKHMSDSQFFAVMTCGLASVAGGTLVGY
HHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHEEH
ASLGVELNYLIAAAFMSAPAGLLMAKILMPETEAQAEDVQMENVEMPKATNVVEAMADGA
HHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHCCHHCCCCCCHHHHHHHHHHHH
MSGLRIAVAVGATLLAFVSVIALLNGLLGWVGSWFGISLSFELILGYLFAPVAWLLGIPW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
HEAITAGSLIGNKIVVNEFVAFIQLMQVKQDLSAHSQAIVTFALCGFANISTMAMLIGGL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLVPEKRSFISKYGFRAITAGVLANLMSASIAGVILSL
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]