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The map label for this gene is hemA

Identifier: 37679114

GI number: 37679114

Start: 930067

End: 931326

Strand: Direct

Name: hemA

Synonym: VV0930

Alternate gene names: 37679114

Gene position: 930067-931326 (Clockwise)

Preceding gene: 37679112

Following gene: 37679115

Centisome position: 27.73

GC content: 49.92

Gene sequence:

>1260_bases
ATGTCTTTGCTTGCTATTGGCATAAATCACCACACCGCGTCGGTTGACTTGCGAGAGAAAGTGGCGTTTGGTCCAGACAA
ACTGGCTAACGCACTGCAGCAGCTCAGCCAGCATGAAGCAGTCAATGGCAGCGTGATTCTCTCTACCTGTAACCGCACCG
AAGTGTATTGCGATGTCAAATCGGGTGCACGCAGCAAGGTGATTGATTGGTTAAGCCAGTTTCATCAAATCGGTTTAGAA
GAGCTCAAACCGAGTTTGTATGTGTACGAAGAACAAGCAGCAATTCGCCATCTGATGCGCGTTTCTTGCGGCTTGGATTC
TTTGGTGCTGGGTGAACCACAAATATTAGGGCAGGTGAAACAGGCGTATTCCGACTCGCGTGAACAGCAGGCGGTGGATG
CGTCTTTGGAAAAATTGTTTCAGAAAACCTTTTCCGTTGCTAAGCGCGTCCGCACTGAAACCGACATTGGCGGTAACGCC
GTTTCGGTCGCGTATGCTGCTTGTACGTTAGCCAAACACATTTTTGAATCGTTAGAGAAATCGACGGTTCTATTGGTCGG
TGCTGGTGAAACCATCGAGTTGGTGGCGAAGCACCTTCACGCGAACGGCTGTAGTAAAATGATTGTGGCAAACCGCACTC
GCGAGCGTGCACTGACCTTAGCAGAGCAATTTGATGCTCAGGTGATCAGCTTGCAAGATATTCCCAATCACCTTGCCAAA
GCGGACATAGTGATCAGCTCCACGGCGAGCCCGCTGCCGATCATAGGTAAAGGCATGGTGGAAACTGCGCTTAAGCAACG
TCGTCATCAGCCTATGTTGTTGGTGGATATTGCAGTCCCGCGTGATGTGGAAGCGCAAGTGGGCGAATTGAATGATGCTT
ACTTATATACTGTTGACGATCTGCAATCGATTATTGACAACAATATTGAGCAGCGCAAAGTCGAAGCGATCCAAGCAGAA
GCGATCGTGGCGGAAGAAAGTGCCGCGTTTATGAGTTGGCTTCGCTCGCTCCAAGCGGTGGACAGTATTCGTGAGTATCG
CCAGTCGGCCAATGACATTCGTGAGGAATTGCTCAGCAAAGCGCTGTTATCACTGGAAAGCGGTGGTGATCCAGAAAAAG
TACTGCGCGAACTGAGTAATCGCCTGACAAATAAACTCATCCATGCACCCACACGTGCGCTACAATTGGCCGCAGAGCAG
GGTGAGCCCGCAAAATTAACCGTCATTCGCCAAAGCTTAGGGCTGGATGAACTCAAATAA

Upstream 100 bases:

>100_bases
GAAGTAAGGAAAACAAATCCGCTACACCCTTTTAATAAAGTCGTGCATAAAGTAAAATTCGCCTCCTAATTTTCCATTCT
GTACAGAGAAAGCACTATCG

Downstream 100 bases:

>100_bases
TTCTATCAATCAGTAAGATATATAAATGATGAAAGCCTCGATTCTAACCAAGCTAGAAATGCTGGTTGAGCGTTATGAAG
AAGTGCAGCACCTTCTTGGT

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTCNRTEVYCDVKSGARSKVIDWLSQFHQIGLE
ELKPSLYVYEEQAAIRHLMRVSCGLDSLVLGEPQILGQVKQAYSDSREQQAVDASLEKLFQKTFSVAKRVRTETDIGGNA
VSVAYAACTLAKHIFESLEKSTVLLVGAGETIELVAKHLHANGCSKMIVANRTRERALTLAEQFDAQVISLQDIPNHLAK
ADIVISSTASPLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGELNDAYLYTVDDLQSIIDNNIEQRKVEAIQAE
AIVAEESAAFMSWLRSLQAVDSIREYRQSANDIREELLSKALLSLESGGDPEKVLRELSNRLTNKLIHAPTRALQLAAEQ
GEPAKLTVIRQSLGLDELK

Sequences:

>Translated_419_residues
MSLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTCNRTEVYCDVKSGARSKVIDWLSQFHQIGLE
ELKPSLYVYEEQAAIRHLMRVSCGLDSLVLGEPQILGQVKQAYSDSREQQAVDASLEKLFQKTFSVAKRVRTETDIGGNA
VSVAYAACTLAKHIFESLEKSTVLLVGAGETIELVAKHLHANGCSKMIVANRTRERALTLAEQFDAQVISLQDIPNHLAK
ADIVISSTASPLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGELNDAYLYTVDDLQSIIDNNIEQRKVEAIQAE
AIVAEESAAFMSWLRSLQAVDSIREYRQSANDIREELLSKALLSLESGGDPEKVLRELSNRLTNKLIHAPTRALQLAAEQ
GEPAKLTVIRQSLGLDELK
>Mature_418_residues
SLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTCNRTEVYCDVKSGARSKVIDWLSQFHQIGLEE
LKPSLYVYEEQAAIRHLMRVSCGLDSLVLGEPQILGQVKQAYSDSREQQAVDASLEKLFQKTFSVAKRVRTETDIGGNAV
SVAYAACTLAKHIFESLEKSTVLLVGAGETIELVAKHLHANGCSKMIVANRTRERALTLAEQFDAQVISLQDIPNHLAKA
DIVISSTASPLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGELNDAYLYTVDDLQSIIDNNIEQRKVEAIQAEA
IVAEESAAFMSWLRSLQAVDSIREYRQSANDIREELLSKALLSLESGGDPEKVLRELSNRLTNKLIHAPTRALQLAAEQG
EPAKLTVIRQSLGLDELK

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=418, Percent_Identity=60.5263157894737, Blast_Score=500, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 46055; Mature: 45924

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTCNRTEVYCDVK
CCEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECC
SGARSKVIDWLSQFHQIGLEELKPSLYVYEEQAAIRHLMRVSCGLDSLVLGEPQILGQVK
CCCHHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHH
QAYSDSREQQAVDASLEKLFQKTFSVAKRVRTETDIGGNAVSVAYAACTLAKHIFESLEK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
STVLLVGAGETIELVAKHLHANGCSKMIVANRTRERALTLAEQFDAQVISLQDIPNHLAK
CEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCHHEEEHHHHHHHHHH
ADIVISSTASPLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGELNDAYLYTVDD
HCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCEEEEHHH
LQSIIDNNIEQRKVEAIQAEAIVAEESAAFMSWLRSLQAVDSIREYRQSANDIREELLSK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSLESGGDPEKVLRELSNRLTNKLIHAPTRALQLAAEQGEPAKLTVIRQSLGLDELK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEHHHHHCCCCCCC
>Mature Secondary Structure 
SLLAIGINHHTASVDLREKVAFGPDKLANALQQLSQHEAVNGSVILSTCNRTEVYCDVK
CEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECC
SGARSKVIDWLSQFHQIGLEELKPSLYVYEEQAAIRHLMRVSCGLDSLVLGEPQILGQVK
CCCHHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHH
QAYSDSREQQAVDASLEKLFQKTFSVAKRVRTETDIGGNAVSVAYAACTLAKHIFESLEK
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
STVLLVGAGETIELVAKHLHANGCSKMIVANRTRERALTLAEQFDAQVISLQDIPNHLAK
CEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHCHHEEEHHHHHHHHHH
ADIVISSTASPLPIIGKGMVETALKQRRHQPMLLVDIAVPRDVEAQVGELNDAYLYTVDD
HCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCCEEEEHHH
LQSIIDNNIEQRKVEAIQAEAIVAEESAAFMSWLRSLQAVDSIREYRQSANDIREELLSK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALLSLESGGDPEKVLRELSNRLTNKLIHAPTRALQLAAEQGEPAKLTVIRQSLGLDELK
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA