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The map label for this gene is treA [H]

Identifier: 37679080

GI number: 37679080

Start: 898492

End: 900177

Strand: Direct

Name: treA [H]

Synonym: VV0896

Alternate gene names: 37679080

Gene position: 898492-900177 (Clockwise)

Preceding gene: 37679079

Following gene: 37679082

Centisome position: 26.78

GC content: 46.86

Gene sequence:

>1686_bases
ATGACAACACGTAACACAGATGCACATTGGTGGAAAACCGCCACTATCTATCAAATCTACCCAAAAAGTTTTTGCGACAG
CGGGGCAAAGGGGACGGGAGATATTCAAGGCATCATCTCTAAGTTGGAATATTTGAAGCATCTCGGTATTGATGCAATCT
GGCTGACGCCGGTTTACCAATCGCCGATGGTCGATAATGGATACGACATTTCGGATTACTACCGAATTAACCCTCAGTTT
GGCACGATGGCGGATTTTGATGAATTGCTCGAGAAAGCGCATCAGCTCGGAATCCGTCTTATCATGGACATTGTGGTGAA
CCACACCTCGACCGAACACGCTTGGTTTCAATCGGCACTGGGTAACAAAAACAGTCCGTATCGGGATTACTACATCTGGA
AAGACCCGGTCGAAGGAAAGGTGCCCAATAATTGGCAGTCTAAGTTTGGCGGCAGCGCTTGGGCGCTGGATGAACAAACA
GGCCAATATTATCTGCACCTTTTCGCCAAAGAGCAGGCCGATCTCAATTGGGAAAATCCCACTGTTCGTGAGGAAGTGAA
AAACGTTATTCGTTTTTGGGCGGAAAAAGGCGTTGACGGATTTCGTCTGGACGTCATCAATCTGATTTCTAAGCAACAAG
ATTTTTGCGACGATGAGATTGGCGATGGGCGTCGTTTCTATACTGATGGACCGCGTGTGCACGACTATCTCCAAGAGATC
AGTCAAGCTGTTTTCCAAAAGTATGGCAGTGTGACAGTAGGTGAGATGTCATCGACAACCTTAGAGCATTGTCAGCAGTA
CTCCTCACTTGATGGCAAAGAGCTTTCCATGGTGTTCAATTTCCATCACCTGAAAGTGGATTATCCAAATGGTGAAAAAT
GGACCAAGGCACCATTTGACTTTCTCCAGCTCAAACAGATCTTTAATCATTGGCAAACCGGCCTGAATGGGAAAGGGTGG
GGAGCGCTCTTTTGGTGTAACCATGATCAGCCACGTATCGTGAGCCGTTTGGGCAACGATCAAGCGTATCGCGTTGAATC
GGCAAAAATGTTGGCTGCCTCGGTTCATATGATGCAAGGCACGCCTTATGTTTATCAAGGCGAAGAAATTGGCATGACCA
ACCCAGGGTATACAGCGATTGAACAGTATCGTGATGTTGAAAGCACCAACATGTATCAGATCATGGTTGAGCAGCAAGGA
ATTGACCATGACGAAATGATGGCGATTTTGGCACAAAAGTCTCGTGATAATTCACGCACCCCAATGCAGTGGTCAGAAGA
AAAACACGCAGGATTTACGCAAGGAGAACCGTGGTTAGCGGTGGCGAGTAACTACCCGAAGATCAACGCGGAAGCGGCGG
TGGCGGATCTCAATTCGGTGTTCTATTTCTATAAGCGATTGATTGAACTGCGTAAAGAAGTGCCAGTGATCACCCAAGGT
GATTATCAAGACTTATTACCCGAGCATCAGAGTGTGTTTGCTTATGCACGGACCAGTGCGGCTCAGCAACTGGTGTGCAT
CAATAACTACTACGGGGAAGAGGTGGAGTGTGTATTGCCATTGGGTCTCGACATGCGTAAAGCGAAATGTTTGCTGTCTA
ATTACCAAAATCGACCGAGTGCCATGGCTTCACATCACCAAGTACTCAAACCTTACGAGACTCGTATTCTCTTGATTGAA
CGTTAA

Upstream 100 bases:

>100_bases
AGCCAAAGGCGAACTCGAACCGGTAAACGCATAATTTCATCGATTTGGAGTGGCGAATGGCCACTCCGCTTTGTTTCTCT
TCGGTAAGTGAGTCTTTACC

Downstream 100 bases:

>100_bases
GTTTGTTGTTGGTTATAAAGAACGCTAACGGCACGCCCCTAATACGTTCAAAGGCTTTGGAAGTTCCAAAGCCTTTTTTT
GTTGCAGGGTAAAACAGATT

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MTTRNTDAHWWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQSPMVDNGYDISDYYRINPQF
GTMADFDELLEKAHQLGIRLIMDIVVNHTSTEHAWFQSALGNKNSPYRDYYIWKDPVEGKVPNNWQSKFGGSAWALDEQT
GQYYLHLFAKEQADLNWENPTVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEIGDGRRFYTDGPRVHDYLQEI
SQAVFQKYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYPNGEKWTKAPFDFLQLKQIFNHWQTGLNGKGW
GALFWCNHDQPRIVSRLGNDQAYRVESAKMLAASVHMMQGTPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVEQQG
IDHDEMMAILAQKSRDNSRTPMQWSEEKHAGFTQGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEVPVITQG
DYQDLLPEHQSVFAYARTSAAQQLVCINNYYGEEVECVLPLGLDMRKAKCLLSNYQNRPSAMASHHQVLKPYETRILLIE
R

Sequences:

>Translated_561_residues
MTTRNTDAHWWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQSPMVDNGYDISDYYRINPQF
GTMADFDELLEKAHQLGIRLIMDIVVNHTSTEHAWFQSALGNKNSPYRDYYIWKDPVEGKVPNNWQSKFGGSAWALDEQT
GQYYLHLFAKEQADLNWENPTVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEIGDGRRFYTDGPRVHDYLQEI
SQAVFQKYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYPNGEKWTKAPFDFLQLKQIFNHWQTGLNGKGW
GALFWCNHDQPRIVSRLGNDQAYRVESAKMLAASVHMMQGTPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVEQQG
IDHDEMMAILAQKSRDNSRTPMQWSEEKHAGFTQGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEVPVITQG
DYQDLLPEHQSVFAYARTSAAQQLVCINNYYGEEVECVLPLGLDMRKAKCLLSNYQNRPSAMASHHQVLKPYETRILLIE
R
>Mature_560_residues
TTRNTDAHWWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQSPMVDNGYDISDYYRINPQFG
TMADFDELLEKAHQLGIRLIMDIVVNHTSTEHAWFQSALGNKNSPYRDYYIWKDPVEGKVPNNWQSKFGGSAWALDEQTG
QYYLHLFAKEQADLNWENPTVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEIGDGRRFYTDGPRVHDYLQEIS
QAVFQKYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYPNGEKWTKAPFDFLQLKQIFNHWQTGLNGKGWG
ALFWCNHDQPRIVSRLGNDQAYRVESAKMLAASVHMMQGTPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVEQQGI
DHDEMMAILAQKSRDNSRTPMQWSEEKHAGFTQGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEVPVITQGD
YQDLLPEHQSVFAYARTSAAQQLVCINNYYGEEVECVLPLGLDMRKAKCLLSNYQNRPSAMASHHQVLKPYETRILLIER

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=497, Percent_Identity=30.5835010060362, Blast_Score=238, Evalue=9e-63,
Organism=Homo sapiens, GI61744479, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI65506891, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI61744475, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI61744477, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI61744483, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI61744481, Length=121, Percent_Identity=30.5785123966942, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1790687, Length=501, Percent_Identity=61.87624750499, Blast_Score=663, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=192, Percent_Identity=32.2916666666667, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=31.8681318681319, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=491, Percent_Identity=25.050916496945, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32565753, Length=203, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321726, Length=588, Percent_Identity=38.265306122449, Blast_Score=387, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322241, Length=584, Percent_Identity=38.6986301369863, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6322021, Length=584, Percent_Identity=38.6986301369863, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6324416, Length=584, Percent_Identity=38.6986301369863, Blast_Score=382, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6321731, Length=584, Percent_Identity=38.8698630136986, Blast_Score=380, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6319776, Length=584, Percent_Identity=38.6986301369863, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6322245, Length=582, Percent_Identity=37.2852233676976, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI221330053, Length=506, Percent_Identity=36.7588932806324, Blast_Score=291, Evalue=7e-79,
Organism=Drosophila melanogaster, GI24586597, Length=543, Percent_Identity=34.2541436464088, Blast_Score=286, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24586591, Length=497, Percent_Identity=37.8269617706237, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24586599, Length=569, Percent_Identity=33.0404217926186, Blast_Score=280, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24583747, Length=565, Percent_Identity=33.4513274336283, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24583749, Length=565, Percent_Identity=33.4513274336283, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24583745, Length=529, Percent_Identity=34.2155009451796, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI45549022, Length=530, Percent_Identity=33.7735849056604, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586593, Length=545, Percent_Identity=34.4954128440367, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24586589, Length=539, Percent_Identity=35.8070500927644, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24586587, Length=593, Percent_Identity=31.1973018549747, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI281360393, Length=488, Percent_Identity=31.9672131147541, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 64648; Mature: 64517

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRNTDAHWWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQ
CCCCCCCCCEEEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCC
SPMVDNGYDISDYYRINPQFGTMADFDELLEKAHQLGIRLIMDIVVNHTSTEHAWFQSAL
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GNKNSPYRDYYIWKDPVEGKVPNNWQSKFGGSAWALDEQTGQYYLHLFAKEQADLNWENP
CCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEEEEHHCCCCCCCCC
TVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEIGDGRRFYTDGPRVHDYLQEI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHH
SQAVFQKYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYPNGEKWTKAPFD
HHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCCCCHH
FLQLKQIFNHWQTGLNGKGWGALFWCNHDQPRIVSRLGNDQAYRVESAKMLAASVHMMQG
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVEQQGIDHDEMMAILAQKSRDNSRT
CCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCC
PMQWSEEKHAGFTQGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEVPVITQG
CCCCCCHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
DYQDLLPEHQSVFAYARTSAAQQLVCINNYYGEEVECVLPLGLDMRKAKCLLSNYQNRPS
CHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCH
AMASHHQVLKPYETRILLIER
HHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure 
TTRNTDAHWWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQ
CCCCCCCCEEEEEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCC
SPMVDNGYDISDYYRINPQFGTMADFDELLEKAHQLGIRLIMDIVVNHTSTEHAWFQSAL
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
GNKNSPYRDYYIWKDPVEGKVPNNWQSKFGGSAWALDEQTGQYYLHLFAKEQADLNWENP
CCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECCCCCCEEEEEEEHHCCCCCCCCC
TVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEIGDGRRFYTDGPRVHDYLQEI
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHH
SQAVFQKYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYPNGEKWTKAPFD
HHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCCCCCCCCCHH
FLQLKQIFNHWQTGLNGKGWGALFWCNHDQPRIVSRLGNDQAYRVESAKMLAASVHMMQG
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCEEEHHHHHHHHHHHHHHCC
TPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVEQQGIDHDEMMAILAQKSRDNSRT
CCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCC
PMQWSEEKHAGFTQGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEVPVITQG
CCCCCCHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECC
DYQDLLPEHQSVFAYARTSAAQQLVCINNYYGEEVECVLPLGLDMRKAKCLLSNYQNRPS
CHHHHCCHHHHHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCH
AMASHHQVLKPYETRILLIER
HHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]