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The map label for this gene is dsdC [H]

Identifier: 37678965

GI number: 37678965

Start: 789622

End: 790608

Strand: Direct

Name: dsdC [H]

Synonym: VV0780

Alternate gene names: 37678965

Gene position: 789622-790608 (Clockwise)

Preceding gene: 37678962

Following gene: 37678966

Centisome position: 23.54

GC content: 46.91

Gene sequence:

>987_bases
GTGAGTTTCTTAGGTTTACAACTTGGTAACAATCGATATAAATTAATTGCTGCTTATAGAAAAACTAAACGCAAGTGGGC
GAAAATGATCAAAAGCACTTATGTATCGGCACTGCATACTTTTGTGGAAGTGGGTAAGTACCCCAGTTTAACCGAGGCAG
CAAGGCAACTTTGCTTAACTACCGGTGCGGTGAGCCAGCAGCTATTACAGCTAGAACAGCAACTTGGTTTTAGTTTGTTT
GAACGGCACTCTCGCGGTATTCGTTTTACGGAGAAAGGTCGACAACTTCATCAATGTGCAGCGTTGCACTTTGGAGAAAT
GGCAGCGGAAATCCAACGTTTAAAGCAAGAGCAGAGTCGCCCACAGGAAGTGCGTCTTAAACTGACCCCTTCTTTTGCCT
TCAAATGGCTGGTGCCAAAATTGGAAAGCTTTCACCAACAGTACCCTGATATTCAAATCCAAATTTTTGCCGAAGGGGCT
TTGGTGAATAGTGATACGCGAGATTTTGACCTCGCGATTGATTACCGCCCACACCCGTTTCGTCAAGCCAATACCGAGTT
GCTATTAGATGAATATTTGCTGCCTGTGATGAATCCCAGATACTTGCAAACACACGCGTGGTTGCACAATGCCGTGTATG
CGCTAGATGAGTGGAGTCAAGTGGTGCTTTTGCACGACGCTATGCCGTGGGAAAATGCACCAAGGGATTATGAATGGCTT
AGTTGGGTCGCGCAGAGACGACTCGATTTACCAACCGAAAGAGGCCATTTCTTTAACCGGACCGATATGGCGATGTCGGC
TGCTGAGGCAGGCGTGGGGATTGCCATGGCACGCATGGCGCTGATTGATGATGAGTTACAAACCGGCCGCTTAGTCTCTC
CTTTTCAGCCCATCCGAGCAGAGGCGGGTTACTATTTGATCCACAACAGCAAAAACGACAGTACCGCAGCGTTTACCACT
TGGCTTAAGCAACAAATTTCAAATTGA

Upstream 100 bases:

>100_bases
CTGATAGCCCGATTTTTGTAGATACCACGCGCTCATCAAGCCAACCACACCACTGCCCAATACCACTGCTTTCATCGATT
TTCTCCTGATTAGAAACAGC

Downstream 100 bases:

>100_bases
GTGGCAACTCAATAACTAGCTCCTACACTTACTTTTATACCGTGGTCATAACAAATAAATCCAAATCGGTATGACAAGAG
GGGCAGCAAATGAAGTCAGA

Product: transcriptional regulator

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSFLGLQLGNNRYKLIAAYRKTKRKWAKMIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLF
ERHSRGIRFTEKGRQLHQCAALHFGEMAAEIQRLKQEQSRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGA
LVNSDTRDFDLAIDYRPHPFRQANTELLLDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWL
SWVAQRRLDLPTERGHFFNRTDMAMSAAEAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTT
WLKQQISN

Sequences:

>Translated_328_residues
MSFLGLQLGNNRYKLIAAYRKTKRKWAKMIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLF
ERHSRGIRFTEKGRQLHQCAALHFGEMAAEIQRLKQEQSRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGA
LVNSDTRDFDLAIDYRPHPFRQANTELLLDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWL
SWVAQRRLDLPTERGHFFNRTDMAMSAAEAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTT
WLKQQISN
>Mature_327_residues
SFLGLQLGNNRYKLIAAYRKTKRKWAKMIKSTYVSALHTFVEVGKYPSLTEAARQLCLTTGAVSQQLLQLEQQLGFSLFE
RHSRGIRFTEKGRQLHQCAALHFGEMAAEIQRLKQEQSRPQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGAL
VNSDTRDFDLAIDYRPHPFRQANTELLLDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWLS
WVAQRRLDLPTERGHFFNRTDMAMSAAEAGVGIAMARMALIDDELQTGRLVSPFQPIRAEAGYYLIHNSKNDSTAAFTTW
LKQQISN

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=303, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789173, Length=293, Percent_Identity=32.4232081911263, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786448, Length=309, Percent_Identity=28.4789644012945, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790262, Length=170, Percent_Identity=30.5882352941176, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=261, Percent_Identity=23.7547892720307, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=141, Percent_Identity=31.2056737588652, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=130, Percent_Identity=29.2307692307692, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 37931; Mature: 37800

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLGLQLGNNRYKLIAAYRKTKRKWAKMIKSTYVSALHTFVEVGKYPSLTEAARQLCLT
CCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TGAVSQQLLQLEQQLGFSLFERHSRGIRFTEKGRQLHQCAALHFGEMAAEIQRLKQEQSR
HHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGALVNSDTRDFDLAIDYRPHPF
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCEEEEEECCCCCC
RQANTELLLDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHH
SWVAQRRLDLPTERGHFFNRTDMAMSAAEAGVGIAMARMALIDDELQTGRLVSPFQPIRA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
EAGYYLIHNSKNDSTAAFTTWLKQQISN
CCCEEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SFLGLQLGNNRYKLIAAYRKTKRKWAKMIKSTYVSALHTFVEVGKYPSLTEAARQLCLT
CEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
TGAVSQQLLQLEQQLGFSLFERHSRGIRFTEKGRQLHQCAALHFGEMAAEIQRLKQEQSR
HHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQEVRLKLTPSFAFKWLVPKLESFHQQYPDIQIQIFAEGALVNSDTRDFDLAIDYRPHPF
CCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCEEECCCCCCEEEEEECCCCCC
RQANTELLLDEYLLPVMNPRYLQTHAWLHNAVYALDEWSQVVLLHDAMPWENAPRDYEWL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHH
SWVAQRRLDLPTERGHFFNRTDMAMSAAEAGVGIAMARMALIDDELQTGRLVSPFQPIRA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHC
EAGYYLIHNSKNDSTAAFTTWLKQQISN
CCCEEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]