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The map label for this gene is estR [H]

Identifier: 37678924

GI number: 37678924

Start: 744870

End: 745775

Strand: Direct

Name: estR [H]

Synonym: VV0740

Alternate gene names: 37678924

Gene position: 744870-745775 (Clockwise)

Preceding gene: 37678919

Following gene: 37678925

Centisome position: 22.21

GC content: 44.59

Gene sequence:

>906_bases
ATGAATAAATGGCCCAGTCTGAAGCAGTTACACTATCTGATTACCCTGCATGAAACGCGACATTTTAGTGACGCCGCAGA
ACGTTGCTTTGTGAGTCAGTCGACCTTAAGTAAAGGTATACAAAATTTAGAAGAGCTGATTGGTTGTCCACTCTATGAGA
AGAAAGACAAAAAAAGTCCTTTGGTTTTTACTCAGGCCGGTGAACTGGTGGTAATGCATGGCAGAGAGCTATTGGCAAAG
GGGCAAGACTTGGTTGAACTGGGTAGCCTTTGTCAAGGAGACAGCATGCAAGGGCAATTGAAACTGGGCTGCATTCCTAC
CATCGCACCATTTTTATTGTGCGATTTAGTACAAGAAATCAACCAACGTTTTCCTCAACTGAATCTTCTATTGCGTGAAG
ATACAACAACCAATCTATTGACGGCTTTACGTCATGGTGAATTGGACGTATTGATCCTCGCCTTACCCGTTGAGATCGAT
GGGATGGAAAGTCGCGTTGTCGGACAAGATCCTTTTAAAATGGTGATCAGTCGCCATCAAGCAGGGGCGATTAAAGTGCC
AATAAAATATGACGACTTGCCTGACGAGTCAGTGTTTTTATTGGAAAAAGAGCATTGTCTGACCGAGCACGCGGTGTCGG
CCTGTAAACTGACTGATAAAGAGAAGATTAACCCATTTAGTGCGACCAGTTTGCATACCTTAGTGCAAATGGTGGCAAAT
GGACTTGGCACCACCTTTATTCCTCAAATGGCCATCGATCACGGTCTACTGGACAACCAAAACTTAGTGGTGATCGAGCC
TCCTGGCCAGCAAGCTTATCGTGATATTGGGCTGGTTTGGCGGCCAAGTTCTTCACGCAGTAAAACATTTAATCAACTTG
CAGAGGTTGTTTCAGAACTGCTTTAG

Upstream 100 bases:

>100_bases
TTGAAAAAAGCGAATTAAATAGATTAACTTCATCGAAAAAAGCGATAAGAGCAATTCTATCGAGTTAATCATACAAACGA
CGGTAAGTATTAATAATTTT

Downstream 100 bases:

>100_bases
CAAATAGTAGTAGCCAGTAAATCGCAGTAATCAATAAAAGGCGCACTAATTTTAGTGCGCTTTTTAGTATTTTATTCTGA
TGGTGTAGTTTGACTTGTAA

Product: transcriptional regulator

Products: NA

Alternate protein names: Esterase operon transcriptional regulator [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNKWPSLKQLHYLITLHETRHFSDAAERCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVMHGRELLAK
GQDLVELGSLCQGDSMQGQLKLGCIPTIAPFLLCDLVQEINQRFPQLNLLLREDTTTNLLTALRHGELDVLILALPVEID
GMESRVVGQDPFKMVISRHQAGAIKVPIKYDDLPDESVFLLEKEHCLTEHAVSACKLTDKEKINPFSATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIEPPGQQAYRDIGLVWRPSSSRSKTFNQLAEVVSELL

Sequences:

>Translated_301_residues
MNKWPSLKQLHYLITLHETRHFSDAAERCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVMHGRELLAK
GQDLVELGSLCQGDSMQGQLKLGCIPTIAPFLLCDLVQEINQRFPQLNLLLREDTTTNLLTALRHGELDVLILALPVEID
GMESRVVGQDPFKMVISRHQAGAIKVPIKYDDLPDESVFLLEKEHCLTEHAVSACKLTDKEKINPFSATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIEPPGQQAYRDIGLVWRPSSSRSKTFNQLAEVVSELL
>Mature_301_residues
MNKWPSLKQLHYLITLHETRHFSDAAERCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSPLVFTQAGELVVMHGRELLAK
GQDLVELGSLCQGDSMQGQLKLGCIPTIAPFLLCDLVQEINQRFPQLNLLLREDTTTNLLTALRHGELDVLILALPVEID
GMESRVVGQDPFKMVISRHQAGAIKVPIKYDDLPDESVFLLEKEHCLTEHAVSACKLTDKEKINPFSATSLHTLVQMVAN
GLGTTFIPQMAIDHGLLDNQNLVVIEPPGQQAYRDIGLVWRPSSSRSKTFNQLAEVVSELL

Specific function: Transcriptional regulator of the esterase operon [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=36.6438356164384, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI157672245, Length=270, Percent_Identity=24.8148148148148, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788748, Length=304, Percent_Identity=26.3157894736842, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI145693105, Length=255, Percent_Identity=23.5294117647059, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI2367136, Length=278, Percent_Identity=23.7410071942446, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=26.5232974910394, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33543; Mature: 33543

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKWPSLKQLHYLITLHETRHFSDAAERCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSP
CCCCCCHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LVFTQAGELVVMHGRELLAKGQDLVELGSLCQGDSMQGQLKLGCIPTIAPFLLCDLVQEI
EEEECCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRFPQLNLLLREDTTTNLLTALRHGELDVLILALPVEIDGMESRVVGQDPFKMVISRHQ
HHHCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHCC
AGAIKVPIKYDDLPDESVFLLEKEHCLTEHAVSACKLTDKEKINPFSATSLHTLVQMVAN
CCEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLDNQNLVVIEPPGQQAYRDIGLVWRPSSSRSKTFNQLAEVVSEL
CCCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHCCEEECCCCCHHHHHHHHHHHHHHH
L
C
>Mature Secondary Structure
MNKWPSLKQLHYLITLHETRHFSDAAERCFVSQSTLSKGIQNLEELIGCPLYEKKDKKSP
CCCCCCHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LVFTQAGELVVMHGRELLAKGQDLVELGSLCQGDSMQGQLKLGCIPTIAPFLLCDLVQEI
EEEECCCCEEEEECHHHHHCCCHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
NQRFPQLNLLLREDTTTNLLTALRHGELDVLILALPVEIDGMESRVVGQDPFKMVISRHQ
HHHCCCEEEEEECCCHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHCC
AGAIKVPIKYDDLPDESVFLLEKEHCLTEHAVSACKLTDKEKINPFSATSLHTLVQMVAN
CCEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHH
GLGTTFIPQMAIDHGLLDNQNLVVIEPPGQQAYRDIGLVWRPSSSRSKTFNQLAEVVSEL
CCCCHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHCCEEECCCCCHHHHHHHHHHHHHHH
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA