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The map label for this gene is trpR

Identifier: 37678891

GI number: 37678891

Start: 707062

End: 707370

Strand: Direct

Name: trpR

Synonym: VV0707

Alternate gene names: 37678891

Gene position: 707062-707370 (Clockwise)

Preceding gene: 37678890

Following gene: 37678897

Centisome position: 21.08

GC content: 44.34

Gene sequence:

>309_bases
ATGTCGCAACAACCAGAATATACAGACTGGCAACAAATTGTGGATTTGGTCAAGCACAGTGTCGAACAAAAGCAGCATGA
TATGTTATTGACGATGCTGATGACGCCTGACGAACGTGAAGCTTTAGTGTCTAGAGTGAACATCGTTCGTGAGTTATTGA
AAGGCGAGCTTTCCCAGCGACAAATCAGCCAAATGTTGGGCGTTGGTATTGCGACCATTACTCGAGGTTCCAATGAGCTG
AAGTTAAAGTCAGATGAAGATAAAGCGCGCTTGAATCAGTTATTGGAAGGGACGAAAAAAGGCGGTTGA

Upstream 100 bases:

>100_bases
CCTGATGTTTGAAACCTATTATCGAGACATTCTCGGGGTAGATGGTGCGTTCCTAAATCAGCATGAGCTTGAGACTAAAT
ACTGAGATAGGTAAAGAGTA

Downstream 100 bases:

>100_bases
TACCGCCTTTTTTGCTCTTGAGTTCCCATCCTAGCTTAAGTTGGCAGGGAAATGCTCAGGATTGGTAAAAGGAATTAAGG
CTAAGATTAACGCTTGATGG

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSQQPEYTDWQQIVDLVKHSVEQKQHDMLLTMLMTPDEREALVSRVNIVRELLKGELSQRQISQMLGVGIATITRGSNEL
KLKSDEDKARLNQLLEGTKKGG

Sequences:

>Translated_102_residues
MSQQPEYTDWQQIVDLVKHSVEQKQHDMLLTMLMTPDEREALVSRVNIVRELLKGELSQRQISQMLGVGIATITRGSNEL
KLKSDEDKARLNQLLEGTKKGG
>Mature_101_residues
SQQPEYTDWQQIVDLVKHSVEQKQHDMLLTMLMTPDEREALVSRVNIVRELLKGELSQRQISQMLGVGIATITRGSNELK
LKSDEDKARLNQLLEGTKKGG

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

Organism=Escherichia coli, GI1790854, Length=104, Percent_Identity=47.1153846153846, Blast_Score=82, Evalue=7e-18,

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_VIBVU (Q8DEU5)

Other databases:

- EMBL:   AE016795
- RefSeq:   NP_759481.1
- ProteinModelPortal:   Q8DEU5
- SMR:   Q8DEU5
- GeneID:   1177443
- GenomeReviews:   AE016795_GR
- KEGG:   vvu:VV1_0489
- HOGENOM:   HBG677773
- OMA:   NIFHELL
- ProtClustDB:   PRK01381
- BioCyc:   VVUL216895:VV1_0489-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 11604; Mature: 11472

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQPEYTDWQQIVDLVKHSVEQKQHDMLLTMLMTPDEREALVSRVNIVRELLKGELSQR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QISQMLGVGIATITRGSNELKLKSDEDKARLNQLLEGTKKGG
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQQPEYTDWQQIVDLVKHSVEQKQHDMLLTMLMTPDEREALVSRVNIVRELLKGELSQR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QISQMLGVGIATITRGSNELKLKSDEDKARLNQLLEGTKKGG
HHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA