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The map label for this gene is mviN [H]

Identifier: 37678869

GI number: 37678869

Start: 682584

End: 684146

Strand: Direct

Name: mviN [H]

Synonym: VV0685

Alternate gene names: 37678869

Gene position: 682584-684146 (Clockwise)

Preceding gene: 37678867

Following gene: 37678870

Centisome position: 20.35

GC content: 47.66

Gene sequence:

>1563_bases
GTGAGTAAACGACTACTCAAGTCCGGCATGATCGTCAGCGCTATGACGTTGGTTTCTCGTGTTTTAGGCTTAGTGCGCGA
TGTGGTTGTCGCTAATTTAATGGGCGCAGGTGCCAGTGCCGACGTATTTTTCTTTGCCAACAAAATTCCGAATTTCTTAA
GAAGACTTTTTGCTGAGGGAGCGTTCTCTCAAGCCTTTGTGCCAGTACTGACGGAATACCACGCCAGTGGCGATCTAAAC
AAAACGCGGGATCTCATCGCTAAAGCATCAGGGACGCTCGGAGTGATCGTTTCCGTCGTGACGATTTTAGGGGTGCTCGG
TTCTGGCGTTGTCACGGCATTGTTTGGCGCGGGATGGTTTATTGACTGGTTACATGGTGGGCCAGCCGCGGAAAAATTTG
AGCTTGCCAGCTTTATGCTCAAAATCACCTTTCCCTATCTTTGGTTTATCACCTTTGTTGCCTTGTCTGGTGCGATTCTC
AATACCATGGGCAAATTCGCGGTGTCCTCATTTACACCCGTTTTTCTCAACGTGATGATCATTCTCTGTGCATGGTACAT
ATCACCGATCATGGCTCAACCTGAAGTGGGTTTGGCGATAGGGGTGTTTCTGGGTGGTTTAGTACAGTTTCTTTTTCAAA
TGCCCTTCCTTATTAAAGCGGGGGTTTTAGTCAAACCGAAGTGGGGTTGGCGCGATCCGGGCGTGGTCAAAATTCGTACC
TTGATGATCCCCGCTTTATTTGGGGTATCGGTCAGTCAAATAAACTTATTATTTGATACCTTTATCGCTAGCTTCCTGCA
AACTGGTTCGATTTCATGGCTTTACTATTCTGATCGCTTGCTCGAGTTCCCTCTGGGTCTATTTGGTATTGCCATTGCGA
CGGTGATCCTTCCAGCGCTTTCTCGCAAACATGTTGATGCACACAGCGAGGGTTTTGCCCATACCATGGATTGGGGGGTT
CGCATGGTCACCTTACTAGGCATTCCAGCAATGCTCGGTTTGATGGTATTGGCCAAGCCAATGCTGATGGTGCTGTTTAT
GCGTGGTGAGTTTACCCCACAAGATGTGCATCAAGCCTCTCTGTCTCTTTTGGCGTACGCTTCTGGGTTGTTGAATTTTA
TGCTGATTAAGGTACTCGCGCCTGGCTACTATTCTCGTCAAGACACTAAAACGCCAGTGAAATATGGCATTGTTGCTATG
GTGACCAACATGGTGTTTAACGCCATTTTTGCTTGGTTCTATGGTTATGTTGGTTTGGCTATCGCGACCGCTTTGTCTGC
CTTTGTTAACATGGCACTGTTGTACCGAGGTTTGCATATCGCTGGTGTTTATAAAATCTCTCGACGTACGTTTTTATTTA
TCAGTCGTTTAGTGGTTTCTGGTGCGGTGATGGTGGCGGCGATTTTGTGGCAACTTGATGAGATGAGTGTTTGGCTTGAG
TGGACCACCGCCCATCGTGCCGCAATGCTGACGATGTTGATCGGCTTTGGCGCATTGGCGTACGTTGCTTGTGCCTTTTT
ACTCGGGATTCGGGTAAAAGACCTAAAAGCTGGGACAGAGTAA

Upstream 100 bases:

>100_bases
GGATTCTATCAGCATTTTTAGACCAATGCTAATAAATATCCGCGTCTGTCCTAACAAAAGACGGATAAAAGTTAAGCTAC
GGTGATATTTCGAGGTTACA

Downstream 100 bases:

>100_bases
GGTGGATTGGTATATAATCCGCCAGTTTGACACTGCATAAAACGAAAACAGAGGCATTTCGCTGTATCCAAATGGAACTG
ATACGAGGTATACACAATAT

Product: mviN protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSKRLLKSGMIVSAMTLVSRVLGLVRDVVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFSQAFVPVLTEYHASGDLN
KTRDLIAKASGTLGVIVSVVTILGVLGSGVVTALFGAGWFIDWLHGGPAAEKFELASFMLKITFPYLWFITFVALSGAIL
NTMGKFAVSSFTPVFLNVMIILCAWYISPIMAQPEVGLAIGVFLGGLVQFLFQMPFLIKAGVLVKPKWGWRDPGVVKIRT
LMIPALFGVSVSQINLLFDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSEGFAHTMDWGV
RMVTLLGIPAMLGLMVLAKPMLMVLFMRGEFTPQDVHQASLSLLAYASGLLNFMLIKVLAPGYYSRQDTKTPVKYGIVAM
VTNMVFNAIFAWFYGYVGLAIATALSAFVNMALLYRGLHIAGVYKISRRTFLFISRLVVSGAVMVAAILWQLDEMSVWLE
WTTAHRAAMLTMLIGFGALAYVACAFLLGIRVKDLKAGTE

Sequences:

>Translated_520_residues
MSKRLLKSGMIVSAMTLVSRVLGLVRDVVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFSQAFVPVLTEYHASGDLN
KTRDLIAKASGTLGVIVSVVTILGVLGSGVVTALFGAGWFIDWLHGGPAAEKFELASFMLKITFPYLWFITFVALSGAIL
NTMGKFAVSSFTPVFLNVMIILCAWYISPIMAQPEVGLAIGVFLGGLVQFLFQMPFLIKAGVLVKPKWGWRDPGVVKIRT
LMIPALFGVSVSQINLLFDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSEGFAHTMDWGV
RMVTLLGIPAMLGLMVLAKPMLMVLFMRGEFTPQDVHQASLSLLAYASGLLNFMLIKVLAPGYYSRQDTKTPVKYGIVAM
VTNMVFNAIFAWFYGYVGLAIATALSAFVNMALLYRGLHIAGVYKISRRTFLFISRLVVSGAVMVAAILWQLDEMSVWLE
WTTAHRAAMLTMLIGFGALAYVACAFLLGIRVKDLKAGTE
>Mature_519_residues
SKRLLKSGMIVSAMTLVSRVLGLVRDVVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFSQAFVPVLTEYHASGDLNK
TRDLIAKASGTLGVIVSVVTILGVLGSGVVTALFGAGWFIDWLHGGPAAEKFELASFMLKITFPYLWFITFVALSGAILN
TMGKFAVSSFTPVFLNVMIILCAWYISPIMAQPEVGLAIGVFLGGLVQFLFQMPFLIKAGVLVKPKWGWRDPGVVKIRTL
MIPALFGVSVSQINLLFDTFIASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSEGFAHTMDWGVR
MVTLLGIPAMLGLMVLAKPMLMVLFMRGEFTPQDVHQASLSLLAYASGLLNFMLIKVLAPGYYSRQDTKTPVKYGIVAMV
TNMVFNAIFAWFYGYVGLAIATALSAFVNMALLYRGLHIAGVYKISRRTFLFISRLVVSGAVMVAAILWQLDEMSVWLEW
TTAHRAAMLTMLIGFGALAYVACAFLLGIRVKDLKAGTE

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=516, Percent_Identity=41.4728682170543, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 56779; Mature: 56648

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
SKRLLKSGMIVSAMTLVSRVLGLVRDVVVANLMGAGASADVFFFANKIPNFLRRLFAEG
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC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EHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301 [H]