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The map label for this gene is hlyB [H]

Identifier: 37678764

GI number: 37678764

Start: 560817

End: 562073

Strand: Direct

Name: hlyB [H]

Synonym: VV0580

Alternate gene names: 37678764

Gene position: 560817-562073 (Clockwise)

Preceding gene: 37678763

Following gene: 37678765

Centisome position: 16.72

GC content: 49.8

Gene sequence:

>1257_bases
ATGGAAAAGCTGGCTTTTAAGCCCTGGGAAAGGGTGATCTCTGACATTCGCCTCGTTCCCAAAATGATTTTGCTGATGGT
GTTCAGTACCGTTTTGATTGTTGGCAAACAGCTTTGGGATGCCAGCACCTTCTATCAAGCTTTGTTGGCGGCAACGCAAA
ATGAGCAACTCGCGCAACAACATTACGATGAATACATGGTTCAAGTGGCTTGGCAAACGGGCTTATTGATTGTTATGTTT
GTGGTTCTCTTGATGGCGGCTGCCAGCGTGATGCTGCGTCAAACTCGCTATTTAAATGATGCGATCAAATTGATGGCGCA
AAGAAACCTTTCGGTTCCGTTTGGCATGGCTTGTAAAGATGAATATGGCGATGTGGCGCGTGAGCTGGAGAAAACGCGTC
AGCAATTGCATGACATGATCAAAATGCAGATCAACGCCTCTGATGAACTAGCCGGCTTGACGGAAGTGATGACGCTGAGC
ATGTCGGAAACCAAAGAGTCGGCACAAGAAGAGTTCAATGAAATTGATCAACTGGCGACGGCGATGAGCGAAATGACCTC
GACGGTACAAACCGTGGCCGATCACGCCAACAATGCGTCGAGTTTGACCGAGCAAGCCTCGCAACAAGCGAAAAAGGGCC
AGCAATTCTTGCAAGGTACAGTGTCGAAAATGAGTCAATTGTCGTCAGACATTGCTTCTTCAGCTCAAGCCGTGAACCAA
GTGGAAGAGCGAGTCGGTGCCATTGGTAGTGTGGTTGGCACCATTCAAGGCATTTCAGAACAAACCAACTTGTTGGCACT
GAACGCGGCGATTGAAGCTGCTCGTGCTGGTGAGGCGGGTCGTGGCTTTGCCGTTGTTGCCGACGAAGTTCGCAACCTAG
CTCAGCGCACTCAAACGGCAACGGTAGAGATTCAAGACATGATCACTCAGCTGCAAACCAGTGCCAGCAGTGCCGTTGAC
CTCATGGAGAAGAGTGTGGTGCAAGCGGCGGAAGGCGTTGAGTTGGTGTCCAATGCCGGGACGGAATTGGATGGCATTGT
TGGTCAGGTAACCAGCATTAATGACATGAACTTACAAATCGCGACGGCAGCTGGCCAGCAGAGCAGTGTTGCCGCGGAAA
TGGACCAAAACCTTTCCAATGTGCGTGAGTTAGTGGAAGCATCGGTTGTGGTGGTCAGTGAGTTGCTGGAAACCTCGGAA
ATGATGCAAGGCAACGCGGAAGAGTTGGATAAGAAAATCAAATCTTTCAAAGTCTAA

Upstream 100 bases:

>100_bases
ATAGCAAGGTGGCGTTTTTAACGCGCAAAGTATTTAAGCAAAGTGCCCAAAGGCAACATCTTCTTGATACGACTATAAAA
GAACTGGTGGAGAAACAACA

Downstream 100 bases:

>100_bases
GGTTTTAGTCACAATGAAACGCCCACATTACTCATGTGGGCGTTTTTTATTGCAGTAAGTCTGATATAAATAAGAACAAC
CGCTCAACAAGAACAAGGAA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEKLAFKPWERVISDIRLVPKMILLMVFSTVLIVGKQLWDASTFYQALLAATQNEQLAQQHYDEYMVQVAWQTGLLIVMF
VVLLMAAASVMLRQTRYLNDAIKLMAQRNLSVPFGMACKDEYGDVARELEKTRQQLHDMIKMQINASDELAGLTEVMTLS
MSETKESAQEEFNEIDQLATAMSEMTSTVQTVADHANNASSLTEQASQQAKKGQQFLQGTVSKMSQLSSDIASSAQAVNQ
VEERVGAIGSVVGTIQGISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTQTATVEIQDMITQLQTSASSAVD
LMEKSVVQAAEGVELVSNAGTELDGIVGQVTSINDMNLQIATAAGQQSSVAAEMDQNLSNVRELVEASVVVVSELLETSE
MMQGNAEELDKKIKSFKV

Sequences:

>Translated_418_residues
MEKLAFKPWERVISDIRLVPKMILLMVFSTVLIVGKQLWDASTFYQALLAATQNEQLAQQHYDEYMVQVAWQTGLLIVMF
VVLLMAAASVMLRQTRYLNDAIKLMAQRNLSVPFGMACKDEYGDVARELEKTRQQLHDMIKMQINASDELAGLTEVMTLS
MSETKESAQEEFNEIDQLATAMSEMTSTVQTVADHANNASSLTEQASQQAKKGQQFLQGTVSKMSQLSSDIASSAQAVNQ
VEERVGAIGSVVGTIQGISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTQTATVEIQDMITQLQTSASSAVD
LMEKSVVQAAEGVELVSNAGTELDGIVGQVTSINDMNLQIATAAGQQSSVAAEMDQNLSNVRELVEASVVVVSELLETSE
MMQGNAEELDKKIKSFKV
>Mature_418_residues
MEKLAFKPWERVISDIRLVPKMILLMVFSTVLIVGKQLWDASTFYQALLAATQNEQLAQQHYDEYMVQVAWQTGLLIVMF
VVLLMAAASVMLRQTRYLNDAIKLMAQRNLSVPFGMACKDEYGDVARELEKTRQQLHDMIKMQINASDELAGLTEVMTLS
MSETKESAQEEFNEIDQLATAMSEMTSTVQTVADHANNASSLTEQASQQAKKGQQFLQGTVSKMSQLSSDIASSAQAVNQ
VEERVGAIGSVVGTIQGISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTQTATVEIQDMITQLQTSASSAVD
LMEKSVVQAAEGVELVSNAGTELDGIVGQVTSINDMNLQIATAAGQQSSVAAEMDQNLSNVRELVEASVVVVSELLETSE
MMQGNAEELDKKIKSFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=267, Percent_Identity=34.0823970037453, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI2367378, Length=310, Percent_Identity=33.2258064516129, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1788194, Length=314, Percent_Identity=32.1656050955414, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787690, Length=344, Percent_Identity=29.0697674418605, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789453, Length=300, Percent_Identity=28.6666666666667, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 45443; Mature: 45443

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLAFKPWERVISDIRLVPKMILLMVFSTVLIVGKQLWDASTFYQALLAATQNEQLAQQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
HYDEYMVQVAWQTGLLIVMFVVLLMAAASVMLRQTRYLNDAIKLMAQRNLSVPFGMACKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EYGDVARELEKTRQQLHDMIKMQINASDELAGLTEVMTLSMSETKESAQEEFNEIDQLAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSEMTSTVQTVADHANNASSLTEQASQQAKKGQQFLQGTVSKMSQLSSDIASSAQAVNQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEERVGAIGSVVGTIQGISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TVEIQDMITQLQTSASSAVDLMEKSVVQAAEGVELVSNAGTELDGIVGQVTSINDMNLQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEE
ATAAGQQSSVAAEMDQNLSNVRELVEASVVVVSELLETSEMMQGNAEELDKKIKSFKV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MEKLAFKPWERVISDIRLVPKMILLMVFSTVLIVGKQLWDASTFYQALLAATQNEQLAQQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
HYDEYMVQVAWQTGLLIVMFVVLLMAAASVMLRQTRYLNDAIKLMAQRNLSVPFGMACKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
EYGDVARELEKTRQQLHDMIKMQINASDELAGLTEVMTLSMSETKESAQEEFNEIDQLAT
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMSEMTSTVQTVADHANNASSLTEQASQQAKKGQQFLQGTVSKMSQLSSDIASSAQAVNQ
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEERVGAIGSVVGTIQGISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRNLAQRTQTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
TVEIQDMITQLQTSASSAVDLMEKSVVQAAEGVELVSNAGTELDGIVGQVTSINDMNLQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEE
ATAAGQQSSVAAEMDQNLSNVRELVEASVVVVSELLETSEMMQGNAEELDKKIKSFKV
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]