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The map label for this gene is exeA [H]

Identifier: 37678756

GI number: 37678756

Start: 553092

End: 555248

Strand: Direct

Name: exeA [H]

Synonym: VV0572

Alternate gene names: 37678756

Gene position: 553092-555248 (Clockwise)

Preceding gene: 37678754

Following gene: 37678760

Centisome position: 16.49

GC content: 50.67

Gene sequence:

>2157_bases
ATGTATAAGGATTTTTTTGGTTTCTCTGAGCTGCCTTTCTCGATAGTGCCCAATTCCCGCTATCTCTATTTAAGTCAGCG
CCATCGTGAAGCCATCACACATTTACAGGCTGGCCTCGGCGATGGTGGTGGTTTTGCCATGCTGACTGGGGAAGTGGGGA
CGGGGAAAACCACAGTCGCAAAATCAATGTTGGCTAACCTTGACGGCCAAACCTGTGCCGCTTTGCTGCTCAACCCAACC
TTTTCCAGTGTTGAACTGCTTGAAGCCATTTGTGATGAGTTTGGCTTGAGCTACGCGGCCAACGCTTCCCTTAAACAGCT
CAACCAACGCATTTATCAGTTTTTGTTGGAAAATCATCAGCAAAATATCCAAACCTTATTGGTGATTGATGAAGCACAAC
ATTTGGCGGCGGATGTATTGGAGCAGTTGCGTTTATTGACCAATCTGGAAACGGAAACACGCAAGCTGTTAAAAGTGTTG
TTGGTGGGGCAACCTGAACTGCAACAATTACTGCAGACCACACAATTGCGGCAACTTGCTCAGCGCATTACAGGCCGTTA
TCACCTATTGCCACTGAATCCTCAAGAAACCGCAGACTACATTGCGTTTCGTATTCATACCGCTGGGGGAAATCGTACCC
TGTTTGATCACGCCAGCGCCAAAGTGATTGCTCAGTATAGTCATGGTATTCCCCGCCTGATTAACTTGATTTGCGATAAA
GCGTTGCAATTGAGCTATCACCAAGGCGACAAAAAAATCACGAAAGCGACGGTCGAGCGAGCTTGCCAGAACGTGATGGC
ATTTCAGGCTGAGATCTATCAGCAAACCTCAAACCGTTCGTCTTTCCCTTGGGGAAAAGTGTCTGTAGTGGCCGCTTGCG
TTGCTGGAGTGTTGGCTATTGCCAGCTATTGGCCTTTGATCCCCACTGACAATGTTGTTCCCACAGTGCCTCCGGTTGAG
CGAGACAAGCCAGCAACCGAGTTGCCAATACTGCCTTCAGTGCCAGACATCTTGGTGAATGATGAACAGTGGCTTGGTGA
GTCAGCTGTCGCGCGGATGACCACTCGAGCGCAAGGATTAGAAGATCTTTACAAATTATGGGGATATCGAGCAACGCGCA
TCGATACCTTGTGTGAACAGCCATCCACGTCGATTTTCCAGTGCCAAGTTCGGCAGCTTAATTGGCAAGAGTTGCAGCAA
ACGCCACACCCTTTGTTGCTGACACTGCAGCATGAAGGGCAACGGGCTTACGTTGTCTTGCTGGAAGTCAACTCAGAGCG
CGTCGTTCTGCTTACGGGCGAGCAACGTCTCACATTCACGGTTCCACAATTGATGTCGTTATGGCGGGGCGAAGTCACCG
ATCTATGGCCAATGCCTCTGAGAGAGACATTGCGCCTAGGTATGCACGGCGAGGCTATTGCAGTTTTGGACCAATTGCTC
GCCAAAGCACTCAATGATGAACCGTTAAAGACGACGCAGTTTAATGCTGAGCTGATGCAGCGAGTGGAATGGTTTCAACG
TTGGCAAGCGATGACCGAGGATGGCATCGCCGGTCAGCGTACTTTGGCGCGTTTGCAGCACATGGTCTCATTGTCCGAGC
CGTGGCGAGACTTCACCAAGGCTGAGAAGCAAGGCGAAGAGCAGGCGATGCGCTATCCTGAGTTTCCCTCGCTCGCACCG
CTTCCCAGAACATACCCATTGGCGGAAACTGGCGACGCTATCAACGTGGCCGATCAAACAAGCCCCACTTTGGTCGCGAG
CCCATCAATACCGAGTGAAGAAAAGAAAACAGCGGACGAGCGACTGTTTGAAAACCTCGACCTGTCAGGCTTATCGCCAG
AACTGGCGCAAAAAGTCGAAAATGCCTTGCTGGTGGAGACGCAAACCGACCACTCACCGCAAACGGAGTCAACGGTTTCA
AGGCTCGATCTGAGCGCGGAAAAATGGCATGGGCGCTTGCCGCCACTCAATTTGCAGACACACATGTATTCGAGCGATCC
GAAACGTCGCTGGTTGAAGATTAATGGTGCGGAGTTCCATCAAGGTGAGTGGATCGATAACCAGATTCAACTGGTGGAGA
TTTCAGCGCAGTCGGTGATTGTTGAGTTCCAAGGAGAGCAGATCGAAATTCCAGCGCTCTATGAATGGAAAGGCTAA

Upstream 100 bases:

>100_bases
ACGCGTGTGACCTCGAATATTTGCTTATCTGACTGGACATTGTAGCAAGCAATGGTACTTTGCTCTCTATTCAATTGACG
TATTTGCATTTGGTCTGTGT

Downstream 100 bases:

>100_bases
AGAGGAACAACAAGGGTTCATCAGCCGAAGAGTGAGAAAGAAATCGGGCCGCGAATGCGGCCCGTTTTGATGTTTATGCC
CAGCCTGAGTTTGACTTCTT

Product: putative general secretion pathway protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MYKDFFGFSELPFSIVPNSRYLYLSQRHREAITHLQAGLGDGGGFAMLTGEVGTGKTTVAKSMLANLDGQTCAALLLNPT
FSSVELLEAICDEFGLSYAANASLKQLNQRIYQFLLENHQQNIQTLLVIDEAQHLAADVLEQLRLLTNLETETRKLLKVL
LVGQPELQQLLQTTQLRQLAQRITGRYHLLPLNPQETADYIAFRIHTAGGNRTLFDHASAKVIAQYSHGIPRLINLICDK
ALQLSYHQGDKKITKATVERACQNVMAFQAEIYQQTSNRSSFPWGKVSVVAACVAGVLAIASYWPLIPTDNVVPTVPPVE
RDKPATELPILPSVPDILVNDEQWLGESAVARMTTRAQGLEDLYKLWGYRATRIDTLCEQPSTSIFQCQVRQLNWQELQQ
TPHPLLLTLQHEGQRAYVVLLEVNSERVVLLTGEQRLTFTVPQLMSLWRGEVTDLWPMPLRETLRLGMHGEAIAVLDQLL
AKALNDEPLKTTQFNAELMQRVEWFQRWQAMTEDGIAGQRTLARLQHMVSLSEPWRDFTKAEKQGEEQAMRYPEFPSLAP
LPRTYPLAETGDAINVADQTSPTLVASPSIPSEEKKTADERLFENLDLSGLSPELAQKVENALLVETQTDHSPQTESTVS
RLDLSAEKWHGRLPPLNLQTHMYSSDPKRRWLKINGAEFHQGEWIDNQIQLVEISAQSVIVEFQGEQIEIPALYEWKG

Sequences:

>Translated_718_residues
MYKDFFGFSELPFSIVPNSRYLYLSQRHREAITHLQAGLGDGGGFAMLTGEVGTGKTTVAKSMLANLDGQTCAALLLNPT
FSSVELLEAICDEFGLSYAANASLKQLNQRIYQFLLENHQQNIQTLLVIDEAQHLAADVLEQLRLLTNLETETRKLLKVL
LVGQPELQQLLQTTQLRQLAQRITGRYHLLPLNPQETADYIAFRIHTAGGNRTLFDHASAKVIAQYSHGIPRLINLICDK
ALQLSYHQGDKKITKATVERACQNVMAFQAEIYQQTSNRSSFPWGKVSVVAACVAGVLAIASYWPLIPTDNVVPTVPPVE
RDKPATELPILPSVPDILVNDEQWLGESAVARMTTRAQGLEDLYKLWGYRATRIDTLCEQPSTSIFQCQVRQLNWQELQQ
TPHPLLLTLQHEGQRAYVVLLEVNSERVVLLTGEQRLTFTVPQLMSLWRGEVTDLWPMPLRETLRLGMHGEAIAVLDQLL
AKALNDEPLKTTQFNAELMQRVEWFQRWQAMTEDGIAGQRTLARLQHMVSLSEPWRDFTKAEKQGEEQAMRYPEFPSLAP
LPRTYPLAETGDAINVADQTSPTLVASPSIPSEEKKTADERLFENLDLSGLSPELAQKVENALLVETQTDHSPQTESTVS
RLDLSAEKWHGRLPPLNLQTHMYSSDPKRRWLKINGAEFHQGEWIDNQIQLVEISAQSVIVEFQGEQIEIPALYEWKG
>Mature_718_residues
MYKDFFGFSELPFSIVPNSRYLYLSQRHREAITHLQAGLGDGGGFAMLTGEVGTGKTTVAKSMLANLDGQTCAALLLNPT
FSSVELLEAICDEFGLSYAANASLKQLNQRIYQFLLENHQQNIQTLLVIDEAQHLAADVLEQLRLLTNLETETRKLLKVL
LVGQPELQQLLQTTQLRQLAQRITGRYHLLPLNPQETADYIAFRIHTAGGNRTLFDHASAKVIAQYSHGIPRLINLICDK
ALQLSYHQGDKKITKATVERACQNVMAFQAEIYQQTSNRSSFPWGKVSVVAACVAGVLAIASYWPLIPTDNVVPTVPPVE
RDKPATELPILPSVPDILVNDEQWLGESAVARMTTRAQGLEDLYKLWGYRATRIDTLCEQPSTSIFQCQVRQLNWQELQQ
TPHPLLLTLQHEGQRAYVVLLEVNSERVVLLTGEQRLTFTVPQLMSLWRGEVTDLWPMPLRETLRLGMHGEAIAVLDQLL
AKALNDEPLKTTQFNAELMQRVEWFQRWQAMTEDGIAGQRTLARLQHMVSLSEPWRDFTKAEKQGEEQAMRYPEFPSLAP
LPRTYPLAETGDAINVADQTSPTLVASPSIPSEEKKTADERLFENLDLSGLSPELAQKVENALLVETQTDHSPQTESTVS
RLDLSAEKWHGRLPPLNLQTHMYSSDPKRRWLKINGAEFHQGEWIDNQIQLVEISAQSVIVEFQGEQIEIPALYEWKG

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG3267

COG function: function code U; Type II secretory pathway, component ExeA (predicted ATPase)

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exeA family [H]

Homologues:

Organism=Escherichia coli, GI1789720, Length=240, Percent_Identity=25.4166666666667, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00004 AAA; PF01471 PG_binding_1 [H]

EC number: NA

Molecular weight: Translated: 80908; Mature: 80908

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDFFGFSELPFSIVPNSRYLYLSQRHREAITHLQAGLGDGGGFAMLTGEVGTGKTTVA
CCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
KSMLANLDGQTCAALLLNPTFSSVELLEAICDEFGLSYAANASLKQLNQRIYQFLLENHQ
HHHHHCCCCCCEEHEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QNIQTLLVIDEAQHLAADVLEQLRLLTNLETETRKLLKVLLVGQPELQQLLQTTQLRQLA
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITGRYHLLPLNPQETADYIAFRIHTAGGNRTLFDHASAKVIAQYSHGIPRLINLICDK
HHHCCCEEEEECCCHHCCCEEEEEEEECCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHH
ALQLSYHQGDKKITKATVERACQNVMAFQAEIYQQTSNRSSFPWGKVSVVAACVAGVLAI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ASYWPLIPTDNVVPTVPPVERDKPATELPILPSVPDILVNDEQWLGESAVARMTTRAQGL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCHHHHHHHHHHHHHH
EDLYKLWGYRATRIDTLCEQPSTSIFQCQVRQLNWQELQQTPHPLLLTLQHEGQRAYVVL
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHCCCCCEEEEEEECCCEEEEEE
LEVNSERVVLLTGEQRLTFTVPQLMSLWRGEVTDLWPMPLRETLRLGMHGEAIAVLDQLL
EEECCCEEEEEECCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHH
AKALNDEPLKTTQFNAELMQRVEWFQRWQAMTEDGIAGQRTLARLQHMVSLSEPWRDFTK
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEKQGEEQAMRYPEFPSLAPLPRTYPLAETGDAINVADQTSPTLVASPSIPSEEKKTADE
HHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCHHHHHHHH
RLFENLDLSGLSPELAQKVENALLVETQTDHSPQTESTVSRLDLSAEKWHGRLPPLNLQT
HHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEE
HMYSSDPKRRWLKINGAEFHQGEWIDNQIQLVEISAQSVIVEFQGEQIEIPALYEWKG
CCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEECCEEECCCC
>Mature Secondary Structure
MYKDFFGFSELPFSIVPNSRYLYLSQRHREAITHLQAGLGDGGGFAMLTGEVGTGKTTVA
CCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHH
KSMLANLDGQTCAALLLNPTFSSVELLEAICDEFGLSYAANASLKQLNQRIYQFLLENHQ
HHHHHCCCCCCEEHEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QNIQTLLVIDEAQHLAADVLEQLRLLTNLETETRKLLKVLLVGQPELQQLLQTTQLRQLA
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRITGRYHLLPLNPQETADYIAFRIHTAGGNRTLFDHASAKVIAQYSHGIPRLINLICDK
HHHCCCEEEEECCCHHCCCEEEEEEEECCCCCEEECCCCHHHHHHHHCCHHHHHHHHHHH
ALQLSYHQGDKKITKATVERACQNVMAFQAEIYQQTSNRSSFPWGKVSVVAACVAGVLAI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ASYWPLIPTDNVVPTVPPVERDKPATELPILPSVPDILVNDEQWLGESAVARMTTRAQGL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHCHHHHHHHHHHHHHH
EDLYKLWGYRATRIDTLCEQPSTSIFQCQVRQLNWQELQQTPHPLLLTLQHEGQRAYVVL
HHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHCCCCCEEEEEEECCCEEEEEE
LEVNSERVVLLTGEQRLTFTVPQLMSLWRGEVTDLWPMPLRETLRLGMHGEAIAVLDQLL
EEECCCEEEEEECCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHH
AKALNDEPLKTTQFNAELMQRVEWFQRWQAMTEDGIAGQRTLARLQHMVSLSEPWRDFTK
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEKQGEEQAMRYPEFPSLAPLPRTYPLAETGDAINVADQTSPTLVASPSIPSEEKKTADE
HHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECCCCCCHHHHHHHH
RLFENLDLSGLSPELAQKVENALLVETQTDHSPQTESTVSRLDLSAEKWHGRLPPLNLQT
HHHHCCCCCCCCHHHHHHHHHEEEEEECCCCCCCHHHHHHHHCCCHHHHCCCCCCCCCEE
HMYSSDPKRRWLKINGAEFHQGEWIDNQIQLVEISAQSVIVEFQGEQIEIPALYEWKG
CCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEEECCCEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7961440 [H]