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The map label for this gene is mlaC [H]

Identifier: 37678642

GI number: 37678642

Start: 445201

End: 445860

Strand: Direct

Name: mlaC [H]

Synonym: VV0458

Alternate gene names: 37678642

Gene position: 445201-445860 (Clockwise)

Preceding gene: 37678641

Following gene: 37678643

Centisome position: 13.27

GC content: 46.36

Gene sequence:

>660_bases
ATGAAACTAAGAAGGACTAATTCGATGAAAAGATTCTTTTTGACCTGTCTCTCGCTGTTGATGTCGCTTAATGTATTGGC
GAGCACTGCAGTGGACAAAGCCGAGCCGTATCAAATGATGAAGCAGGTTTCAGAGCAGGCTTTTGCGCGTTTAAAGGCAG
AGCAACCTAAAATTCAGCAAGATCCGGACTACCTCAAAGTGGTGGTAGAAGAAGAGCTGATGCCATACGTGAATGAAAAG
TACGCGGCACTGAAGTTATTGGGTACAAATCTCAAAGGGGCAAAGCGTGAAGACGTCACCGCGTTTATTGACGCGTTTCG
CGCGTACTTAGTGAGCTCTTATGCGCAGGTATTGACGCAATACACGGATCAGAAAATTCTCTTTGGCCCGGAACCTAAGG
TAGAAGACGGCCAGCGCATCACCAGTGTGAAAGTTGATATCATTGATACCCCCCGTCCAAACATTAAGCTAGAGTTCAAA
TTGCGTCGTGAGAATAACGGTGATTGGCTGGCTTTTGATATGGTTGCCGAAGGGATCAGCTTACTCTCCAGCAAGCAGTC
GGAGTGGAATGGTAAAATTCGCCAAGATGGTATTCTTGCCGTCGCCAACGAACTGGAAGCATTAGCGAAACAACCGATTC
GTTTTGAGGCAAAAAACTGA

Upstream 100 bases:

>100_bases
GAGCAGATGCTTAAAGATGGTGACTTTATTGAAGACACCAAATCGGCATTGGTATTGGAAGATTTGATTGGCCAAGTGCT
GTATAGCGTCGGCAACAAAG

Downstream 100 bases:

>100_bases
TGTCACACCCGCAATGGCAGCAATCGACAGACGAGAAAGTCAGCTTAAGTGGTAATTTGGATCGTGAACAGGTGCCATCA
CTGTGGCGTTTTGCTCAGAC

Product: ABC-type transport system, auxiliary component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKLRRTNSMKRFFLTCLSLLMSLNVLASTAVDKAEPYQMMKQVSEQAFARLKAEQPKIQQDPDYLKVVVEEELMPYVNEK
YAALKLLGTNLKGAKREDVTAFIDAFRAYLVSSYAQVLTQYTDQKILFGPEPKVEDGQRITSVKVDIIDTPRPNIKLEFK
LRRENNGDWLAFDMVAEGISLLSSKQSEWNGKIRQDGILAVANELEALAKQPIRFEAKN

Sequences:

>Translated_219_residues
MKLRRTNSMKRFFLTCLSLLMSLNVLASTAVDKAEPYQMMKQVSEQAFARLKAEQPKIQQDPDYLKVVVEEELMPYVNEK
YAALKLLGTNLKGAKREDVTAFIDAFRAYLVSSYAQVLTQYTDQKILFGPEPKVEDGQRITSVKVDIIDTPRPNIKLEFK
LRRENNGDWLAFDMVAEGISLLSSKQSEWNGKIRQDGILAVANELEALAKQPIRFEAKN
>Mature_219_residues
MKLRRTNSMKRFFLTCLSLLMSLNVLASTAVDKAEPYQMMKQVSEQAFARLKAEQPKIQQDPDYLKVVVEEELMPYVNEK
YAALKLLGTNLKGAKREDVTAFIDAFRAYLVSSYAQVLTQYTDQKILFGPEPKVEDGQRITSVKVDIIDTPRPNIKLEFK
LRRENNGDWLAFDMVAEGISLLSSKQSEWNGKIRQDGILAVANELEALAKQPIRFEAKN

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=211, Percent_Identity=38.3886255924171, Blast_Score=160, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24967; Mature: 24967

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRRTNSMKRFFLTCLSLLMSLNVLASTAVDKAEPYQMMKQVSEQAFARLKAEQPKIQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DPDYLKVVVEEELMPYVNEKYAALKLLGTNLKGAKREDVTAFIDAFRAYLVSSYAQVLTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YTDQKILFGPEPKVEDGQRITSVKVDIIDTPRPNIKLEFKLRRENNGDWLAFDMVAEGIS
HCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCEEHHHHHHHHHH
LLSSKQSEWNGKIRQDGILAVANELEALAKQPIRFEAKN
HHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure
MKLRRTNSMKRFFLTCLSLLMSLNVLASTAVDKAEPYQMMKQVSEQAFARLKAEQPKIQQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
DPDYLKVVVEEELMPYVNEKYAALKLLGTNLKGAKREDVTAFIDAFRAYLVSSYAQVLTQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YTDQKILFGPEPKVEDGQRITSVKVDIIDTPRPNIKLEFKLRRENNGDWLAFDMVAEGIS
HCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCEEEEEEEEECCCCCEEHHHHHHHHHH
LLSSKQSEWNGKIRQDGILAVANELEALAKQPIRFEAKN
HHHCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]