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The map label for this gene is mpg1 [H]

Identifier: 37678498

GI number: 37678498

Start: 323240

End: 324301

Strand: Direct

Name: mpg1 [H]

Synonym: VV0314

Alternate gene names: 37678498

Gene position: 323240-324301 (Clockwise)

Preceding gene: 37678497

Following gene: 37678499

Centisome position: 9.64

GC content: 45.86

Gene sequence:

>1062_bases
ATGAAAAATAATTGGAAGAAGGCAGTTCTGTCGCCAGATGCAACAATAAAAGAAGCATTACGTGTTATTGATGCAGAATC
GCTTCGCGTTGCCCTTGTTGTTGATGAGAAAGGGATACTCCAAGGTGTTGTGACTGATGGCGATATCCGAAGAGGGCTGC
TTGCTGGCAAGGCACTGGAGACGATGCTATCTGAAGTAATGAATCGTAAGCCTATCACGGCAAGTGTTTCTGCGGATCGT
GATGATTTAATTGCGAGAATGAACAAAAGTGATTTGCTGTTTATCCCTCTTGTAGATGGTCCTTACTTAGCTGGTCTAGC
AACTCTGCATGGAGCATTAGTTGATAAGCCACTATATCAAAATCCGGTATTTTTGATGGCGGGCGGATTTGGTACTCGTT
TGCGTCCGCTGACGGATAGCTGTCCAAAGCCCATGCTCAAAATCGGCAACAAACCGATCCTTGAAACGGTGATCCGTAGT
TTTATTAAGGCGGGCTTCGTCAATTTCTATATCTCAACTCACTACATGCCAGAGTTGATCCATGCTCACTTTGGTGATGG
TTCAGGGTTCGGTGTCAATATCACGTATGTCCACGAGGAGTCACCATTGGGCACTGGTGGTGCGCTGGGATTATTGCCGA
AAGATCTGCCAAAAGATTTGCCGCTTATTATGATGAATGGTGATGTGCTGACCAAGGTCGATTTTCAACGCCTTCTCGAT
TTTCACGTGACCCATGACGCCGACGCAACCATGTGTGTTCGCGAATACGACTATCAAATTCCCTACGGCGTGATCAACGG
CGAAGGCAACAAAATTACCAGCATGGTGGAGAAGCCGATTCAACGTTTCTTTGTCAATGCAGGGATTTACGTGGTTTCTC
CGAGAGTCATTCAATCGGTACCCGAAAATCATCGTATTGATATGCCGACGCTATTAGAACAACACATGCAGGAAAGAAAC
AACGTCTTGATGTTCCCAATTCACGAGTACTGGCTGGATATCGGCCGAATGGATGATTTCAATCGAGCGCAAGCGGACAT
TCATACTTTGGGATTGGACTAA

Upstream 100 bases:

>100_bases
GATGCAGTATTGTGGGAGCTGGAGTCACTATTCGTAGCAATGTTGTTGCAGATATGACTGTGAGTGGGAAAGTCGTAGCA
AGGTAATAAGTTGGTTAGAA

Downstream 100 bases:

>100_bases
TGGAACGAGTTGCTGTTGTTGGGCTAGGAAATATCGCGACTCGCCATCGACGGAATTTAAAACATTTATTCCCCAGCGCA
CTGCTGTATGCGATGTCGGC

Product: putative sugar-phosphate nucleotide transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKNNWKKAVLSPDATIKEALRVIDAESLRVALVVDEKGILQGVVTDGDIRRGLLAGKALETMLSEVMNRKPITASVSADR
DDLIARMNKSDLLFIPLVDGPYLAGLATLHGALVDKPLYQNPVFLMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRS
FIKAGFVNFYISTHYMPELIHAHFGDGSGFGVNITYVHEESPLGTGGALGLLPKDLPKDLPLIMMNGDVLTKVDFQRLLD
FHVTHDADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHRIDMPTLLEQHMQERN
NVLMFPIHEYWLDIGRMDDFNRAQADIHTLGLD

Sequences:

>Translated_353_residues
MKNNWKKAVLSPDATIKEALRVIDAESLRVALVVDEKGILQGVVTDGDIRRGLLAGKALETMLSEVMNRKPITASVSADR
DDLIARMNKSDLLFIPLVDGPYLAGLATLHGALVDKPLYQNPVFLMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRS
FIKAGFVNFYISTHYMPELIHAHFGDGSGFGVNITYVHEESPLGTGGALGLLPKDLPKDLPLIMMNGDVLTKVDFQRLLD
FHVTHDADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHRIDMPTLLEQHMQERN
NVLMFPIHEYWLDIGRMDDFNRAQADIHTLGLD
>Mature_353_residues
MKNNWKKAVLSPDATIKEALRVIDAESLRVALVVDEKGILQGVVTDGDIRRGLLAGKALETMLSEVMNRKPITASVSADR
DDLIARMNKSDLLFIPLVDGPYLAGLATLHGALVDKPLYQNPVFLMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRS
FIKAGFVNFYISTHYMPELIHAHFGDGSGFGVNITYVHEESPLGTGGALGLLPKDLPKDLPLIMMNGDVLTKVDFQRLLD
FHVTHDADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSVPENHRIDMPTLLEQHMQERN
NVLMFPIHEYWLDIGRMDDFNRAQADIHTLGLD

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=230, Percent_Identity=33.4782608695652, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI11761619, Length=230, Percent_Identity=33.4782608695652, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790224, Length=242, Percent_Identity=25.2066115702479, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788351, Length=237, Percent_Identity=26.1603375527426, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=232, Percent_Identity=30.1724137931034, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320148, Length=230, Percent_Identity=34.7826086956522, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21355443, Length=228, Percent_Identity=32.8947368421053, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24644084, Length=228, Percent_Identity=32.8947368421053, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39306; Mature: 39306

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNWKKAVLSPDATIKEALRVIDAESLRVALVVDEKGILQGVVTDGDIRRGLLAGKALE
CCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHH
TMLSEVMNRKPITASVSADRDDLIARMNKSDLLFIPLVDGPYLAGLATLHGALVDKPLYQ
HHHHHHHCCCCCEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
NPVFLMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSFIKAGFVNFYISTHYMPELI
CCEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEEEEEHHHHHHHH
HAHFGDGSGFGVNITYVHEESPLGTGGALGLLPKDLPKDLPLIMMNGDVLTKVDFQRLLD
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHH
FHVTHDADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSV
HHCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHC
PENHRIDMPTLLEQHMQERNNVLMFPIHEYWLDIGRMDDFNRAQADIHTLGLD
CCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCHHHHHHEEECCC
>Mature Secondary Structure
MKNNWKKAVLSPDATIKEALRVIDAESLRVALVVDEKGILQGVVTDGDIRRGLLAGKALE
CCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHH
TMLSEVMNRKPITASVSADRDDLIARMNKSDLLFIPLVDGPYLAGLATLHGALVDKPLYQ
HHHHHHHCCCCCEEECCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
NPVFLMAGGFGTRLRPLTDSCPKPMLKIGNKPILETVIRSFIKAGFVNFYISTHYMPELI
CCEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHEEEEEHHHHHHHH
HAHFGDGSGFGVNITYVHEESPLGTGGALGLLPKDLPKDLPLIMMNGDVLTKVDFQRLLD
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEHHHHHHHHH
FHVTHDADATMCVREYDYQIPYGVINGEGNKITSMVEKPIQRFFVNAGIYVVSPRVIQSV
HHCCCCCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHC
PENHRIDMPTLLEQHMQERNNVLMFPIHEYWLDIGRMDDFNRAQADIHTLGLD
CCCCCCCCHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]