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The map label for this gene is 37678328

Identifier: 37678328

GI number: 37678328

Start: 154392

End: 155774

Strand: Direct

Name: 37678328

Synonym: VV0144

Alternate gene names: NA

Gene position: 154392-155774 (Clockwise)

Preceding gene: 37678327

Following gene: 37678329

Centisome position: 4.6

GC content: 39.7

Gene sequence:

>1383_bases
ATGTTAAGACTATGGCAAGAGGAGTGTGTTGGATCGGCTTTAGAAAAGTATCTAGCTGGACATTCACATTTTCAGGTTCA
GGCGACTCCAGGGGCTGGAAAAACGGTGGCTGCTGCCGAAATTGCCAAAAGGCTGTATGACTTAGACAAAATTGACCTGG
TCCTCTGTTTTTCGCCATCATTAACGATTGCTGATGGTATCAAAAATACCTTTTCATGGCGATTGGGATGCTCTTTTTCC
GGTGGACTTGGTTCAATAGGTGCATCGTTTACATATCAGAGTATGAAATACCTTAGAGATAGCTTTTGGGAAACAATTAA
AAAGCACCGCGTATTGGTTGTATTTGATGAGATTCACCATTGTTCAGGTGATGAAATTGAAAATGCCAATGTATGGGGTG
AGCAAATTTTGAGACAAATTCAAGGGATTGCTGCGTTTACATTATCCCTATCTGGCACTCCTTGGCGCTCAGATTTATTG
CCAATTACGTTAGCACAGTATTCTGATGCAGAAGGTCGTATCCACTGTGATTATCAATACGGTTTAAAGCAAGCGATTAT
CGATAAGGTCTGTCGCTCACCTAAAATTGTACTAATTGATAATGATCGCTTATCTATTTCAGAAAGTGGACAATCAAAGT
CATTTTCGTCAATTCCTGACCTTTTAAAGCAATCAGCAACTCCGTATCAAAGCATTTTGCAAAATATTGATGCAATGACT
TATGTACTTGGCCTTGGTTGCAAAAAGCTAGCAGATATACGTATGGATAACCCTAATGCCGGTGGTTTGGTTGTTGCTTC
ATCAGTAGGACATGCAATCGAAATTCAGAAAGTTTTGACTGAGACATATGAGCAAAGTACAGAGATAGTCACTTACTATC
ATGAAAATCCACTAGAAAAAATCAATGGGTATCGAAACGGAACGACTCAGTGGATTATCAGCGTCGGAATGATTAGTGAG
GGAACCGATATCCCACGTCTACAAGTCTGTTGCCATTTAAGTTTTGTGAAGACAGAACTTTATTTCAGGCAAGTTTTAGG
ACGAATTTTGCGAACGCATGAATCCTCGAATCAGCAAGCTTGGTTGTACACTTTTGCTGAAGAAAGCCTAGTGAGTTTTG
CTGAGCAGATCGAGCAAGATATTCCGGACTCATGCTTATTTATCAAACCAGATAATTGGCAAGATAGACCTCAAGCTTCT
GTTTCGTTAAATCGAGCCTATTTCTCTGATCAACAAAAGAAAAAAACTGATATTGGGAAGACACAGCTTAGTTGGGATAA
AGAACGTTTGGAAAAACCGTCAATCATAACTGCATACTCAGCTTCTTCTGGTCAATTGAACTTAGGAAATTTCAGAGAGC
GTGTAATTGCTGCATTTCAGTAA

Upstream 100 bases:

>100_bases
TAAAACTATCCGAAGAAACTAGAGAACGCTCTGTTAGATATCTAGCCAAAATAAATGTTCTTAATCACGCCCTAAAGCTT
AGTAATTGTGGGGAAGTAAA

Downstream 100 bases:

>100_bases
TAAATATTTTTAATATTAGACAATATGTTAGCGAGGTATTGATATGTTCTACATCGGTGTTAGCCATTATTACGCAACAG
GTGAAGGCCTCACAATGTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLRLWQEECVGSALEKYLAGHSHFQVQATPGAGKTVAAAEIAKRLYDLDKIDLVLCFSPSLTIADGIKNTFSWRLGCSFS
GGLGSIGASFTYQSMKYLRDSFWETIKKHRVLVVFDEIHHCSGDEIENANVWGEQILRQIQGIAAFTLSLSGTPWRSDLL
PITLAQYSDAEGRIHCDYQYGLKQAIIDKVCRSPKIVLIDNDRLSISESGQSKSFSSIPDLLKQSATPYQSILQNIDAMT
YVLGLGCKKLADIRMDNPNAGGLVVASSVGHAIEIQKVLTETYEQSTEIVTYYHENPLEKINGYRNGTTQWIISVGMISE
GTDIPRLQVCCHLSFVKTELYFRQVLGRILRTHESSNQQAWLYTFAEESLVSFAEQIEQDIPDSCLFIKPDNWQDRPQAS
VSLNRAYFSDQQKKKTDIGKTQLSWDKERLEKPSIITAYSASSGQLNLGNFRERVIAAFQ

Sequences:

>Translated_460_residues
MLRLWQEECVGSALEKYLAGHSHFQVQATPGAGKTVAAAEIAKRLYDLDKIDLVLCFSPSLTIADGIKNTFSWRLGCSFS
GGLGSIGASFTYQSMKYLRDSFWETIKKHRVLVVFDEIHHCSGDEIENANVWGEQILRQIQGIAAFTLSLSGTPWRSDLL
PITLAQYSDAEGRIHCDYQYGLKQAIIDKVCRSPKIVLIDNDRLSISESGQSKSFSSIPDLLKQSATPYQSILQNIDAMT
YVLGLGCKKLADIRMDNPNAGGLVVASSVGHAIEIQKVLTETYEQSTEIVTYYHENPLEKINGYRNGTTQWIISVGMISE
GTDIPRLQVCCHLSFVKTELYFRQVLGRILRTHESSNQQAWLYTFAEESLVSFAEQIEQDIPDSCLFIKPDNWQDRPQAS
VSLNRAYFSDQQKKKTDIGKTQLSWDKERLEKPSIITAYSASSGQLNLGNFRERVIAAFQ
>Mature_460_residues
MLRLWQEECVGSALEKYLAGHSHFQVQATPGAGKTVAAAEIAKRLYDLDKIDLVLCFSPSLTIADGIKNTFSWRLGCSFS
GGLGSIGASFTYQSMKYLRDSFWETIKKHRVLVVFDEIHHCSGDEIENANVWGEQILRQIQGIAAFTLSLSGTPWRSDLL
PITLAQYSDAEGRIHCDYQYGLKQAIIDKVCRSPKIVLIDNDRLSISESGQSKSFSSIPDLLKQSATPYQSILQNIDAMT
YVLGLGCKKLADIRMDNPNAGGLVVASSVGHAIEIQKVLTETYEQSTEIVTYYHENPLEKINGYRNGTTQWIISVGMISE
GTDIPRLQVCCHLSFVKTELYFRQVLGRILRTHESSNQQAWLYTFAEESLVSFAEQIEQDIPDSCLFIKPDNWQDRPQAS
VSLNRAYFSDQQKKKTDIGKTQLSWDKERLEKPSIITAYSASSGQLNLGNFRERVIAAFQ

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2917 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: NA

Molecular weight: Translated: 51611; Mature: 51611

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLWQEECVGSALEKYLAGHSHFQVQATPGAGKTVAAAEIAKRLYDLDKIDLVLCFSPS
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
LTIADGIKNTFSWRLGCSFSGGLGSIGASFTYQSMKYLRDSFWETIKKHRVLVVFDEIHH
CCHHHCCCCCCEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCC
CSGDEIENANVWGEQILRQIQGIAAFTLSLSGTPWRSDLLPITLAQYSDAEGRIHCDYQY
CCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEHHH
GLKQAIIDKVCRSPKIVLIDNDRLSISESGQSKSFSSIPDLLKQSATPYQSILQNIDAMT
HHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YVLGLGCKKLADIRMDNPNAGGLVVASSVGHAIEIQKVLTETYEQSTEIVTYYHENPLEK
HHHHCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHH
INGYRNGTTQWIISVGMISEGTDIPRLQVCCHLSFVKTELYFRQVLGRILRTHESSNQQA
HCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
WLYTFAEESLVSFAEQIEQDIPDSCLFIKPDNWQDRPQASVSLNRAYFSDQQKKKTDIGK
EEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEHHHHHCCHHHHHHCCCC
TQLSWDKERLEKPSIITAYSASSGQLNLGNFRERVIAAFQ
HHCCCCHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHCC
>Mature Secondary Structure
MLRLWQEECVGSALEKYLAGHSHFQVQATPGAGKTVAAAEIAKRLYDLDKIDLVLCFSPS
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCC
LTIADGIKNTFSWRLGCSFSGGLGSIGASFTYQSMKYLRDSFWETIKKHRVLVVFDEIHH
CCHHHCCCCCCEEEECCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCC
CSGDEIENANVWGEQILRQIQGIAAFTLSLSGTPWRSDLLPITLAQYSDAEGRIHCDYQY
CCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEHHH
GLKQAIIDKVCRSPKIVLIDNDRLSISESGQSKSFSSIPDLLKQSATPYQSILQNIDAMT
HHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YVLGLGCKKLADIRMDNPNAGGLVVASSVGHAIEIQKVLTETYEQSTEIVTYYHENPLEK
HHHHCCHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHH
INGYRNGTTQWIISVGMISEGTDIPRLQVCCHLSFVKTELYFRQVLGRILRTHESSNQQA
HCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
WLYTFAEESLVSFAEQIEQDIPDSCLFIKPDNWQDRPQASVSLNRAYFSDQQKKKTDIGK
EEEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEHHHHHCCHHHHHHCCCC
TQLSWDKERLEKPSIITAYSASSGQLNLGNFRERVIAAFQ
HHCCCCHHHCCCCCEEEEECCCCCCEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]