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The map label for this gene is luxQ [H]

Identifier: 37678325

GI number: 37678325

Start: 151234

End: 153030

Strand: Direct

Name: luxQ [H]

Synonym: VV0141

Alternate gene names: 37678325

Gene position: 151234-153030 (Clockwise)

Preceding gene: 37678324

Following gene: 37678327

Centisome position: 4.51

GC content: 37.9

Gene sequence:

>1797_bases
GTGAATTATAAATACTCACAAAAGTTCAATGTTATGGAAGCTTTAATTGCGCTAGCAATAGGCATAACTCTCAGTTTTTT
CTTTTCATTTAAAACTCAAAACTCCCTTCTAGAGGCCACTGAAAGCTCAATCGTTGCTCATTCTGCAAGCCTTGTCCACA
TGAGAAGCTATATACATTTAACTCAGAGAGAAGATGGTGACCACAAGATAAATAAACTACTTTCTGAAATACAAAAGCTA
ACCTCTGAGTTAAACACTTTAAAAGAAGCTAGCAACGACATTAACGTTAGATTTCCTCAAATGATTTGGGTAGGAAATCC
CCTCCCTTCTGTAGTTGAGGAGTACGTAAAAACTGCGGATAAACAGTTGGTATTTCTTGATAAAATGCTTAAAGCAAAAC
AACAGATAGTACCAGAGGTTTCATTAATCGAATTAGAGAGGCAGGTGTTTTCAGAAGAGATGGATGAAGCAGCGGAACAT
GTTCATGAACGTTTGATGGATAACATCTTCTTAACCAGTAAAGCAGCCGTCTATACTTTAATACTATTCATTATTTTAAT
ATTCTCTGCCGTTTTTCTTTATCTCAATCATTACATTATAGAGTTGAAGAAGACCAAGCTAGCATTACAGGTAGCTGTAA
ATAAGGCAGAGGAAGCCAACTTAGCTAAGTCTATGTTTTTAGCAACAATGAGTCATGAGATAAGAACTCCAATGAATGGT
GTTATAGGAATGACACAGTTACTCATATCGGATAATAAAGATCCAAGTATTCAGACGCACTTAGATACGCTATTGGAGTC
AGGTGAACACCTAATGGTGGTCATAAACGAAATTCTTGATTTTTCAAATCTAGAACAAGGAAGTTTAGTTTTTGTTCAGG
AAGAATTTGAGCTAAGCAAACTATTGGTCCCTATAAAAAATTCTTTTCAACCACAGGCTTCTGAAAAAAAACTTCAGCTT
ATATTCGACACCAATAGCTTGCCTGAAGATCTAATTTTAGTTGGTGATAAAACTCGTATACGTCAAGTTATTTACAATTT
AGTGGGTAATGCCATCAAGTTCACCTCTGATGGACAGGTTAAGGTTGTTTTAAAATATGAAAGTGATAAAAATGAGCTTT
GTATTCAGGTATCTGATACCGGAATTGGCATACCATCCCATCGTTTAAAAGGCATTTTTAATGCGTTCGAACAAGCAGAT
GTTAGAACGATGCACGATTTTGGAGGTACAGGGTTAGGTTTATCCATCGTGAAAAAAATATGCTTATCAATGGGGGGGGA
TATTACTGTTACAAGTGAGTTAGGTTCAGGAAGCTGCTTTGTGGCAAAGGTGATAAGCCCAAGAGTAACCACCCTCCGAG
ATCAAAGAACGCTCTCAGGCGAAAAAGACTTTTCCGGTAAGTCAGTCCTTATCGTTGAGGATAACCGTGTTAATCAGCTT
GTTGCTCAACGATTGTGTCAAAAGTTAGGGTTTACTACCTATATTGCATCTAATGGTATAGAAGCTGTTAAAAGGGTGCG
CGAATGTTCTTTTGACGTAATCTTGATGGATCATCAAATGCCACAAATGGGGGGCATAGAAGCGACAAAATTAATACGAA
ATGAGCATGCTTTTCAGGGTATTATTCTTGGATGTACCGCTGATGTTACCAAAGATACAGCCATAGCATTCGTGGACGCT
GGTGCCAATGGAGTAATAACAAAGCCCTTACAATTAGACTCTTTAGGGGAGTTAATAGCACGCAGCGTAACGCTGGCTTG
TAATGCGAGTCGTGATCATCATGTCGTGTTGGAATAG

Upstream 100 bases:

>100_bases
ACATTAATTGTTTGGTTATTGATGGTTGCTTGCTTTTTTTATTATATTGAAAAAGAAAGCTTTATACCTGTTATCCATGA
ATTTCATCTGGAGGACTCAA

Downstream 100 bases:

>100_bases
ATGTCAGTCCGACTCATATTGAATCAAAGAGTTGATTCTTTGAGTAAAAGAGATAGCCTCAATGCTAGAATGCGCTATTT
TTTACGTCGTCTGTAGAGGG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MNYKYSQKFNVMEALIALAIGITLSFFFSFKTQNSLLEATESSIVAHSASLVHMRSYIHLTQREDGDHKINKLLSEIQKL
TSELNTLKEASNDINVRFPQMIWVGNPLPSVVEEYVKTADKQLVFLDKMLKAKQQIVPEVSLIELERQVFSEEMDEAAEH
VHERLMDNIFLTSKAAVYTLILFIILIFSAVFLYLNHYIIELKKTKLALQVAVNKAEEANLAKSMFLATMSHEIRTPMNG
VIGMTQLLISDNKDPSIQTHLDTLLESGEHLMVVINEILDFSNLEQGSLVFVQEEFELSKLLVPIKNSFQPQASEKKLQL
IFDTNSLPEDLILVGDKTRIRQVIYNLVGNAIKFTSDGQVKVVLKYESDKNELCIQVSDTGIGIPSHRLKGIFNAFEQAD
VRTMHDFGGTGLGLSIVKKICLSMGGDITVTSELGSGSCFVAKVISPRVTTLRDQRTLSGEKDFSGKSVLIVEDNRVNQL
VAQRLCQKLGFTTYIASNGIEAVKRVRECSFDVILMDHQMPQMGGIEATKLIRNEHAFQGIILGCTADVTKDTAIAFVDA
GANGVITKPLQLDSLGELIARSVTLACNASRDHHVVLE

Sequences:

>Translated_598_residues
MNYKYSQKFNVMEALIALAIGITLSFFFSFKTQNSLLEATESSIVAHSASLVHMRSYIHLTQREDGDHKINKLLSEIQKL
TSELNTLKEASNDINVRFPQMIWVGNPLPSVVEEYVKTADKQLVFLDKMLKAKQQIVPEVSLIELERQVFSEEMDEAAEH
VHERLMDNIFLTSKAAVYTLILFIILIFSAVFLYLNHYIIELKKTKLALQVAVNKAEEANLAKSMFLATMSHEIRTPMNG
VIGMTQLLISDNKDPSIQTHLDTLLESGEHLMVVINEILDFSNLEQGSLVFVQEEFELSKLLVPIKNSFQPQASEKKLQL
IFDTNSLPEDLILVGDKTRIRQVIYNLVGNAIKFTSDGQVKVVLKYESDKNELCIQVSDTGIGIPSHRLKGIFNAFEQAD
VRTMHDFGGTGLGLSIVKKICLSMGGDITVTSELGSGSCFVAKVISPRVTTLRDQRTLSGEKDFSGKSVLIVEDNRVNQL
VAQRLCQKLGFTTYIASNGIEAVKRVRECSFDVILMDHQMPQMGGIEATKLIRNEHAFQGIILGCTADVTKDTAIAFVDA
GANGVITKPLQLDSLGELIARSVTLACNASRDHHVVLE
>Mature_598_residues
MNYKYSQKFNVMEALIALAIGITLSFFFSFKTQNSLLEATESSIVAHSASLVHMRSYIHLTQREDGDHKINKLLSEIQKL
TSELNTLKEASNDINVRFPQMIWVGNPLPSVVEEYVKTADKQLVFLDKMLKAKQQIVPEVSLIELERQVFSEEMDEAAEH
VHERLMDNIFLTSKAAVYTLILFIILIFSAVFLYLNHYIIELKKTKLALQVAVNKAEEANLAKSMFLATMSHEIRTPMNG
VIGMTQLLISDNKDPSIQTHLDTLLESGEHLMVVINEILDFSNLEQGSLVFVQEEFELSKLLVPIKNSFQPQASEKKLQL
IFDTNSLPEDLILVGDKTRIRQVIYNLVGNAIKFTSDGQVKVVLKYESDKNELCIQVSDTGIGIPSHRLKGIFNAFEQAD
VRTMHDFGGTGLGLSIVKKICLSMGGDITVTSELGSGSCFVAKVISPRVTTLRDQRTLSGEKDFSGKSVLIVEDNRVNQL
VAQRLCQKLGFTTYIASNGIEAVKRVRECSFDVILMDHQMPQMGGIEATKLIRNEHAFQGIILGCTADVTKDTAIAFVDA
GANGVITKPLQLDSLGELIARSVTLACNASRDHHVVLE

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=31.7934782608696, Blast_Score=205, Evalue=8e-54,
Organism=Escherichia coli, GI87081816, Length=396, Percent_Identity=32.3232323232323, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=41.5254237288136, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788713, Length=421, Percent_Identity=30.166270783848, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=38.8429752066116, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=24.2798353909465, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=24.5454545454545, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=28.0442804428044, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788393, Length=203, Percent_Identity=25.615763546798, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=25.9259259259259, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790861, Length=230, Percent_Identity=24.3478260869565, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790551, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=26.1306532663317, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=218, Percent_Identity=28.4403669724771, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=147, Percent_Identity=34.6938775510204, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=219, Percent_Identity=23.7442922374429, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66569; Mature: 66569

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKYSQKFNVMEALIALAIGITLSFFFSFKTQNSLLEATESSIVAHSASLVHMRSYIHL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
TQREDGDHKINKLLSEIQKLTSELNTLKEASNDINVRFPQMIWVGNPLPSVVEEYVKTAD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEEECCCCHHHHHHHHHHHC
KQLVFLDKMLKAKQQIVPEVSLIELERQVFSEEMDEAAEHVHERLMDNIFLTSKAAVYTL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILFIILIFSAVFLYLNHYIIELKKTKLALQVAVNKAEEANLAKSMFLATMSHEIRTPMNG
HHHHHHHHHHHHHHHHHHHEEEHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
VIGMTQLLISDNKDPSIQTHLDTLLESGEHLMVVINEILDFSNLEQGSLVFVQEEFELSK
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCEEEEECHHHHHH
LLVPIKNSFQPQASEKKLQLIFDTNSLPEDLILVGDKTRIRQVIYNLVGNAIKFTSDGQV
HHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCE
KVVLKYESDKNELCIQVSDTGIGIPSHRLKGIFNAFEQADVRTMHDFGGTGLGLSIVKKI
EEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHH
CLSMGGDITVTSELGSGSCFVAKVISPRVTTLRDQRTLSGEKDFSGKSVLIVEDNRVNQL
HHHCCCCEEEEECCCCCCEEEEEHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
VAQRLCQKLGFTTYIASNGIEAVKRVRECSFDVILMDHQMPQMGGIEATKLIRNEHAFQG
HHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC
IILGCTADVTKDTAIAFVDAGANGVITKPLQLDSLGELIARSVTLACNASRDHHVVLE
EEEEEECCCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHEEEEEECCCCCEEEEC
>Mature Secondary Structure
MNYKYSQKFNVMEALIALAIGITLSFFFSFKTQNSLLEATESSIVAHSASLVHMRSYIHL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
TQREDGDHKINKLLSEIQKLTSELNTLKEASNDINVRFPQMIWVGNPLPSVVEEYVKTAD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECEEEEECCCCHHHHHHHHHHHC
KQLVFLDKMLKAKQQIVPEVSLIELERQVFSEEMDEAAEHVHERLMDNIFLTSKAAVYTL
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILFIILIFSAVFLYLNHYIIELKKTKLALQVAVNKAEEANLAKSMFLATMSHEIRTPMNG
HHHHHHHHHHHHHHHHHHHEEEHHHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHH
VIGMTQLLISDNKDPSIQTHLDTLLESGEHLMVVINEILDFSNLEQGSLVFVQEEFELSK
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCEEEEECHHHHHH
LLVPIKNSFQPQASEKKLQLIFDTNSLPEDLILVGDKTRIRQVIYNLVGNAIKFTSDGQV
HHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCE
KVVLKYESDKNELCIQVSDTGIGIPSHRLKGIFNAFEQADVRTMHDFGGTGLGLSIVKKI
EEEEEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCHHHHHHH
CLSMGGDITVTSELGSGSCFVAKVISPRVTTLRDQRTLSGEKDFSGKSVLIVEDNRVNQL
HHHCCCCEEEEECCCCCCEEEEEHHCCCHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
VAQRLCQKLGFTTYIASNGIEAVKRVRECSFDVILMDHQMPQMGGIEATKLIRNEHAFQG
HHHHHHHHCCCEEEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCC
IILGCTADVTKDTAIAFVDAGANGVITKPLQLDSLGELIARSVTLACNASRDHHVVLE
EEEEEECCCCCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHEEEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA