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The map label for this gene is yybE [H]

Identifier: 37523996

GI number: 37523996

Start: 4653867

End: 4654733

Strand: Reverse

Name: yybE [H]

Synonym: gll4427

Alternate gene names: 37523996

Gene position: 4654733-4653867 (Counterclockwise)

Preceding gene: NA

Following gene: 37523992

Centisome position: 99.91

GC content: 46.83

Gene sequence:

>867_bases
ATGGATATAAATCAGATTCGCTATTTTTTAGCGATTGTTGAAACAGGCGGATTTACAAAAGCTGCCGACAGTTTACTGAT
CTCTCAACCGTCCTTATCAGTCAGTATTAGAAGATTAGAGCGAGAGCTAGGCGTTACTCTATTCGAGAGAGGGGGGCGGC
GAGCCGTTCTCACGCCTGCGGGTCAGTTCTTTTTAGGAACAGCCAGGGCGATCTGGGATAGGTATCAATTCGTACTGAAC
GGGCTTAGAGACTTTCGTAGTCAACCCACTCTGAGGTTGGGTATCCTCCGCACGTTTCGGATCGACGATTTCTCTAAAAT
GATTATAATCTTTCGAGAGAAATGCTCGAATGCCGTCATTGAGTTTCGGGACGGCACTGTCAAAGATTTGCACAACTGGT
TAGAGCAGGGCGAAGTCGATTTGATTGTGACAGAGTTGACAAGTCTCGAAGATACGGAAACTTCCCTTGCCTTGTTTCAA
CAAGATTATTTACTAGCAGTTCCGCAAAACCACCCATTTGCCCACAGAGACAGGGTTAGTCTGGCTGAACTGGATGATCA
ACCGTTCATCGGGCGAAACAATTGTGAAATTTGGGGTAGAGCACCACAGATGTTTGAAGCCGCAGGTGTTGAACCTCGAG
TCGTCTATTTGGCGGATCGAGAAGAGTGGGCGATTTCCATGATCAAATCTGGATTAGGAATCACCATCATGCCCGTGTGG
CAAGGTTTGTCTGATATTGTGTACGTTCCGATCGCCGAAGCGGATTTGTCTCGAACAGTGGGTCTGAAATGGAGAGCACA
GCAAAACTCAGACATCGTTAAGCTATTTCGAGTCTTTGCAGCTAACTACGCTTGGCAAGGTGTCTAA

Upstream 100 bases:

>100_bases
AGGTCATCTCCATCCTCCAAGCAGCCCTTGTATAGAGCAAGGCGAACTTTTGCATCGGATTCATAGCTAAACTCTATGGG
CGAGTCACTTACTTGATCTT

Downstream 100 bases:

>100_bases
CACAGACCCGTTTAGGTTGCTGAAAAGCTCCAATAATTGGTAGATCTCCATGGGCTGTCCGACTCACTCCACTGAGAGCA
CCATAACGAGCTTGCCCCTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MDINQIRYFLAIVETGGFTKAADSLLISQPSLSVSIRRLERELGVTLFERGGRRAVLTPAGQFFLGTARAIWDRYQFVLN
GLRDFRSQPTLRLGILRTFRIDDFSKMIIIFREKCSNAVIEFRDGTVKDLHNWLEQGEVDLIVTELTSLEDTETSLALFQ
QDYLLAVPQNHPFAHRDRVSLAELDDQPFIGRNNCEIWGRAPQMFEAAGVEPRVVYLADREEWAISMIKSGLGITIMPVW
QGLSDIVYVPIAEADLSRTVGLKWRAQQNSDIVKLFRVFAANYAWQGV

Sequences:

>Translated_288_residues
MDINQIRYFLAIVETGGFTKAADSLLISQPSLSVSIRRLERELGVTLFERGGRRAVLTPAGQFFLGTARAIWDRYQFVLN
GLRDFRSQPTLRLGILRTFRIDDFSKMIIIFREKCSNAVIEFRDGTVKDLHNWLEQGEVDLIVTELTSLEDTETSLALFQ
QDYLLAVPQNHPFAHRDRVSLAELDDQPFIGRNNCEIWGRAPQMFEAAGVEPRVVYLADREEWAISMIKSGLGITIMPVW
QGLSDIVYVPIAEADLSRTVGLKWRAQQNSDIVKLFRVFAANYAWQGV
>Mature_288_residues
MDINQIRYFLAIVETGGFTKAADSLLISQPSLSVSIRRLERELGVTLFERGGRRAVLTPAGQFFLGTARAIWDRYQFVLN
GLRDFRSQPTLRLGILRTFRIDDFSKMIIIFREKCSNAVIEFRDGTVKDLHNWLEQGEVDLIVTELTSLEDTETSLALFQ
QDYLLAVPQNHPFAHRDRVSLAELDDQPFIGRNNCEIWGRAPQMFEAAGVEPRVVYLADREEWAISMIKSGLGITIMPVW
QGLSDIVYVPIAEADLSRTVGLKWRAQQNSDIVKLFRVFAANYAWQGV

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=272, Percent_Identity=27.2058823529412, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=27.3381294964029, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=25.5892255892256, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI157672245, Length=263, Percent_Identity=27.7566539923954, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI2367136, Length=240, Percent_Identity=28.3333333333333, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1787530, Length=270, Percent_Identity=24.4444444444444, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790262, Length=295, Percent_Identity=23.3898305084746, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI145693105, Length=273, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789204, Length=241, Percent_Identity=23.2365145228216, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=285, Percent_Identity=22.1052631578947, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788296, Length=226, Percent_Identity=26.9911504424779, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=214, Percent_Identity=26.1682242990654, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32801; Mature: 32801

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINQIRYFLAIVETGGFTKAADSLLISQPSLSVSIRRLERELGVTLFERGGRRAVLTPA
CCHHHHEEEEEEEECCCCCHHHHHHEECCCCHHHHHHHHHHHHCCHHHHCCCCEEEECCC
GQFFLGTARAIWDRYQFVLNGLRDFRSQPTLRLGILRTFRIDDFSKMIIIFREKCSNAVI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCEE
EFRDGTVKDLHNWLEQGEVDLIVTELTSLEDTETSLALFQQDYLLAVPQNHPFAHRDRVS
EECCCCHHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCH
LAELDDQPFIGRNNCEIWGRAPQMFEAAGVEPRVVYLADREEWAISMIKSGLGITIMPVW
HHHCCCCCCCCCCCCEEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEEHHH
QGLSDIVYVPIAEADLSRTVGLKWRAQQNSDIVKLFRVFAANYAWQGV
CCCCCEEEEEECCCCHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDINQIRYFLAIVETGGFTKAADSLLISQPSLSVSIRRLERELGVTLFERGGRRAVLTPA
CCHHHHEEEEEEEECCCCCHHHHHHEECCCCHHHHHHHHHHHHCCHHHHCCCCEEEECCC
GQFFLGTARAIWDRYQFVLNGLRDFRSQPTLRLGILRTFRIDDFSKMIIIFREKCSNAVI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCEE
EFRDGTVKDLHNWLEQGEVDLIVTELTSLEDTETSLALFQQDYLLAVPQNHPFAHRDRVS
EECCCCHHHHHHHHHCCCEEEEEEEHHCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCCH
LAELDDQPFIGRNNCEIWGRAPQMFEAAGVEPRVVYLADREEWAISMIKSGLGITIMPVW
HHHCCCCCCCCCCCCEEECCCCHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCEEEEHHH
QGLSDIVYVPIAEADLSRTVGLKWRAQQNSDIVKLFRVFAANYAWQGV
CCCCCEEEEEECCCCHHHHCCEEEECCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]