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The map label for this gene is msrB [H]

Identifier: 37523908

GI number: 37523908

Start: 4573668

End: 4574069

Strand: Direct

Name: msrB [H]

Synonym: glr4339

Alternate gene names: 37523908

Gene position: 4573668-4574069 (Clockwise)

Preceding gene: 37523907

Following gene: 37523909

Centisome position: 98.17

GC content: 55.97

Gene sequence:

>402_bases
ATGCAAAAAGTATTAAAAAGTGACCAAGAATGGCGGCAGCAACTGACGCCCGAGCAATATAAGATCACGCGCCAAAAAGG
GACGGAGCGGCCGTTTTGCGGCGTTTTCTACGACCACAAACAACCTGGGGAATACACCTGCGTCTGCTGTGAATTGCCCC
TTTTCACCGCTGAGGCCAAGTTCGACTCCGGCACCGGCTGGCCGAGTTTTCTCGCACCAATAAACGCAGAAAACGTCGCG
ACCCAGAAGGATTTCAGCCATGGCATGAGCCGGGTGGAGGTGCTTTGTGCGCGGTGCGATGCCCACCTCGGTCATGTCTT
TACGGACGGTCCGCCACCCACGAGACTGCGGTACTGTCTGAACTCGGCCGCGTTGGAGTTCGTTCCGCAGGTAAAAAGCT
AG

Upstream 100 bases:

>100_bases
GTGAAGCTTTTCGCAATATTCTATCCAGTGCGGGATTCGAACCTACGCTTAGAGCTTTAGAATTGACAGATAACGGTGAA
CATAACAAGGAGTTACACCG

Downstream 100 bases:

>100_bases
CGCTGCCAAACGACCCACTGGAGAAAGAATGCCATGGCCGAACTGCCCGAGGGTTTTCCGGCGCCCACCCTGCCCGGGGT
GATCGAGATTAAACACTACC

Product: hypothetical protein

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MQKVLKSDQEWRQQLTPEQYKITRQKGTERPFCGVFYDHKQPGEYTCVCCELPLFTAEAKFDSGTGWPSFLAPINAENVA
TQKDFSHGMSRVEVLCARCDAHLGHVFTDGPPPTRLRYCLNSAALEFVPQVKS

Sequences:

>Translated_133_residues
MQKVLKSDQEWRQQLTPEQYKITRQKGTERPFCGVFYDHKQPGEYTCVCCELPLFTAEAKFDSGTGWPSFLAPINAENVA
TQKDFSHGMSRVEVLCARCDAHLGHVFTDGPPPTRLRYCLNSAALEFVPQVKS
>Mature_133_residues
MQKVLKSDQEWRQQLTPEQYKITRQKGTERPFCGVFYDHKQPGEYTCVCCELPLFTAEAKFDSGTGWPSFLAPINAENVA
TQKDFSHGMSRVEVLCARCDAHLGHVFTDGPPPTRLRYCLNSAALEFVPQVKS

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=131, Percent_Identity=57.2519083969466, Blast_Score=160, Evalue=3e-40,
Organism=Homo sapiens, GI301336162, Length=131, Percent_Identity=57.2519083969466, Blast_Score=160, Evalue=3e-40,
Organism=Homo sapiens, GI73089054, Length=131, Percent_Identity=57.2519083969466, Blast_Score=160, Evalue=3e-40,
Organism=Homo sapiens, GI37620216, Length=131, Percent_Identity=57.2519083969466, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=48.0916030534351, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI7706511, Length=100, Percent_Identity=38, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=50, Blast_Score=139, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17553450, Length=120, Percent_Identity=48.3333333333333, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=120, Percent_Identity=48.3333333333333, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=38.5826771653543, Blast_Score=101, Evalue=4e-23,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=48.4375, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=50, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=50, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=50, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=45.9259259259259, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=46.0431654676259, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=46.0431654676259, Blast_Score=135, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15057; Mature: 15057

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVLKSDQEWRQQLTPEQYKITRQKGTERPFCGVFYDHKQPGEYTCVCCELPLFTAEAK
CCHHHCCHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCEEECCCC
FDSGTGWPSFLAPINAENVATQKDFSHGMSRVEVLCARCDAHLGHVFTDGPPPTRLRYCL
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHH
NSAALEFVPQVKS
HHHHHHHHCCCCC
>Mature Secondary Structure
MQKVLKSDQEWRQQLTPEQYKITRQKGTERPFCGVFYDHKQPGEYTCVCCELPLFTAEAK
CCHHHCCHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCEEECCCC
FDSGTGWPSFLAPINAENVATQKDFSHGMSRVEVLCARCDAHLGHVFTDGPPPTRLRYCL
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHH
NSAALEFVPQVKS
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]