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The map label for this gene is ubiB [C]

Identifier: 37523747

GI number: 37523747

Start: 4376512

End: 4378299

Strand: Direct

Name: ubiB [C]

Synonym: glr4178

Alternate gene names: 37523747

Gene position: 4376512-4378299 (Clockwise)

Preceding gene: 37523746

Following gene: 37523748

Centisome position: 93.94

GC content: 60.51

Gene sequence:

>1788_bases
TTGCCCGCCTGCGCTCGGAATTGCAGCGCTTCCGCAACCAGGAAGCCACGTGAAGTCCCTGTCCCCCTCCGCTACCCATT
CGTGATCGTGTCGGCGCCGCCTTCTTCTGCTAAGAACTATCGCTGGAATCGAGTCAACTACTCGCGCACCCGCCGCGTGA
TCGATATTTGGGGCTTCTTTTTGTTGATTCTGTTCTACCGCTGGTGGGACAGCAAAAAGTGGACCTACCGCAGCGGCGAC
AGCGAAGAAAACCGCTCGCGCCGCCAGCGCATGCGGGCCATCTGGACGCGCGAGACAATGCTCGAACTGGGGCCGACTTT
TATCAAGGTCGGGCAACTGTTTTCGACGCGGGCGGACTTGTTCCCGAAAGAATATATCGAAGAACTCTCCAGACTCCAGG
ACGAGGTACCGGCCTTTCCCTACGAACAGGTCGTCGAGATCGTCGAGGACCAGTTCGGCAAACCGATCCCCCAGGTCTTT
CAATTTTTTGATCCGACTCCGATTGCCGCCGCTTCCCTGGGTCAGGTGCACAGAGCCCAGCTGCACTCGGGCGAAGATGT
CGTCGTCAAAGTGCAGCGGCCGGGCCTAGAAAAGCTGTTCAATGTCGATCTCGGTATCCTGCGCGGCATCGCCCAGTACC
TGCAGAATCACCCGCGCTACGGCCGGGGCGGGCGCGAGTGGGTGCCCATCTACGACGAGTGCGCCCGCATCCTCATGCAG
GAGATCGACTATCTCAACGAGGGGCGCAACGCCGACACCTTCCGCCGCAACTTCAAAGACAGCCCCGAAATTTGTGTGCC
GCGGGTCTACTGGCGCTACTCCTCCCCCAGGGTGCTCACCCTCGAATATTTGCCGGGCATCAAAATCAGCAACTACGAGG
CGCTGGAGGCGGCGGGGCTCGACCGGCGGTCGCTGGCGCGCATCGGGGCGCGCTCCTACCTGCAGCAGCTGCTCAACGAC
GGCTTCTTTCACGCCGATCCCCACCCGGGCAACATCGCCGTGCGCCACGACGGGGCGCTGATTTTTTACGACTTCGGCAT
GATGGGCCACATCCAGCCGGGCACCAAAGAGAAGCTCATGGACACCTTTCTTGGGGTGGCCCAATCCGATGCCGACAAGG
TGATCGATTCGCTCATCGAACTGGGGGCCATCAAGAAAAGTGCCGACCGGGTGCCCATCCGCCGCTCGATCGAATTTTTG
CTCACCAACTTCGTCAACCAGCCCTACAACCTGCAGTCGTTCAACTTTGCGGAGTTGACCGACGACATCTACGAAATGGC
TTACGAGCAGCCCTTTCGCTTTCCGGCGACTTTCACGTTTGTGTTGCGGGCCGTCTCGACCCTCGAAGGATTGGGCAAGG
GCCTCGATCCCGATTTCAACTTTATGGACGTGGCCCAGCCTTTTGCCGATCAGCTCATGGCTGTCAATTCAGAATTCGGT
ATGCGCGAATTATTCAACCAGCTCGGCCAGCAGGTGGGCCAGGTCAGCTCGATGACCGTCAACCTGCCCCGGCGCATCGA
GCAAACGCTTGAGCGGGCCGACCGCGGCGAACTGCGGGTGCGCACCAAGTCGATCGAGACGGAGCGATTGCTCAAGCGGC
TCAACTCGGCGGCCATCGGCGGCATCTACAGCGTGCTGTTGGCGGCTTTTCTCATCTGTTCGGTCGTGCTCTACACCGCC
GACCATATTCTCGAGGCGATCGCCGCCTTTGGCCTGGCGGGTCTGCTGTCCTTCGCCCTCGGGCGGGTGCTGCTGCGGTT
GCAGCGCATCGACACCGACTTGCAGTAG

Upstream 100 bases:

>100_bases
GCCGAGACGCTGGCGGACTTGAGCGCCGAGGGCTACACGGCGCGCACCCCGGCGGCTTCCAAAGATGTCCAGCGCAATAT
CGACGAGTTGCGGGCGGAGG

Downstream 100 bases:

>100_bases
CGCCCGGCACGCTAGACAGCTGCGGGAGTCTCATCCTATAGTGTTAGCCTGAAAGCGCTCTGTTGGAGGGAAGGCCATTC
CTGAGCCGATCAACCTGACG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MPACARNCSASATRKPREVPVPLRYPFVIVSAPPSSAKNYRWNRVNYSRTRRVIDIWGFFLLILFYRWWDSKKWTYRSGD
SEENRSRRQRMRAIWTRETMLELGPTFIKVGQLFSTRADLFPKEYIEELSRLQDEVPAFPYEQVVEIVEDQFGKPIPQVF
QFFDPTPIAAASLGQVHRAQLHSGEDVVVKVQRPGLEKLFNVDLGILRGIAQYLQNHPRYGRGGREWVPIYDECARILMQ
EIDYLNEGRNADTFRRNFKDSPEICVPRVYWRYSSPRVLTLEYLPGIKISNYEALEAAGLDRRSLARIGARSYLQQLLND
GFFHADPHPGNIAVRHDGALIFYDFGMMGHIQPGTKEKLMDTFLGVAQSDADKVIDSLIELGAIKKSADRVPIRRSIEFL
LTNFVNQPYNLQSFNFAELTDDIYEMAYEQPFRFPATFTFVLRAVSTLEGLGKGLDPDFNFMDVAQPFADQLMAVNSEFG
MRELFNQLGQQVGQVSSMTVNLPRRIEQTLERADRGELRVRTKSIETERLLKRLNSAAIGGIYSVLLAAFLICSVVLYTA
DHILEAIAAFGLAGLLSFALGRVLLRLQRIDTDLQ

Sequences:

>Translated_595_residues
MPACARNCSASATRKPREVPVPLRYPFVIVSAPPSSAKNYRWNRVNYSRTRRVIDIWGFFLLILFYRWWDSKKWTYRSGD
SEENRSRRQRMRAIWTRETMLELGPTFIKVGQLFSTRADLFPKEYIEELSRLQDEVPAFPYEQVVEIVEDQFGKPIPQVF
QFFDPTPIAAASLGQVHRAQLHSGEDVVVKVQRPGLEKLFNVDLGILRGIAQYLQNHPRYGRGGREWVPIYDECARILMQ
EIDYLNEGRNADTFRRNFKDSPEICVPRVYWRYSSPRVLTLEYLPGIKISNYEALEAAGLDRRSLARIGARSYLQQLLND
GFFHADPHPGNIAVRHDGALIFYDFGMMGHIQPGTKEKLMDTFLGVAQSDADKVIDSLIELGAIKKSADRVPIRRSIEFL
LTNFVNQPYNLQSFNFAELTDDIYEMAYEQPFRFPATFTFVLRAVSTLEGLGKGLDPDFNFMDVAQPFADQLMAVNSEFG
MRELFNQLGQQVGQVSSMTVNLPRRIEQTLERADRGELRVRTKSIETERLLKRLNSAAIGGIYSVLLAAFLICSVVLYTA
DHILEAIAAFGLAGLLSFALGRVLLRLQRIDTDLQ
>Mature_594_residues
PACARNCSASATRKPREVPVPLRYPFVIVSAPPSSAKNYRWNRVNYSRTRRVIDIWGFFLLILFYRWWDSKKWTYRSGDS
EENRSRRQRMRAIWTRETMLELGPTFIKVGQLFSTRADLFPKEYIEELSRLQDEVPAFPYEQVVEIVEDQFGKPIPQVFQ
FFDPTPIAAASLGQVHRAQLHSGEDVVVKVQRPGLEKLFNVDLGILRGIAQYLQNHPRYGRGGREWVPIYDECARILMQE
IDYLNEGRNADTFRRNFKDSPEICVPRVYWRYSSPRVLTLEYLPGIKISNYEALEAAGLDRRSLARIGARSYLQQLLNDG
FFHADPHPGNIAVRHDGALIFYDFGMMGHIQPGTKEKLMDTFLGVAQSDADKVIDSLIELGAIKKSADRVPIRRSIEFLL
TNFVNQPYNLQSFNFAELTDDIYEMAYEQPFRFPATFTFVLRAVSTLEGLGKGLDPDFNFMDVAQPFADQLMAVNSEFGM
RELFNQLGQQVGQVSSMTVNLPRRIEQTLERADRGELRVRTKSIETERLLKRLNSAAIGGIYSVLLAAFLICSVVLYTAD
HILEAIAAFGLAGLLSFALGRVLLRLQRIDTDLQ

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=272, Percent_Identity=35.2941176470588, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI40254938, Length=248, Percent_Identity=33.8709677419355, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI217035081, Length=203, Percent_Identity=33.9901477832512, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI32261307, Length=335, Percent_Identity=22.3880597014925, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI34147522, Length=274, Percent_Identity=25.9124087591241, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27363457, Length=287, Percent_Identity=24.390243902439, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI217416386, Length=283, Percent_Identity=24.7349823321555, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367309, Length=382, Percent_Identity=31.151832460733, Blast_Score=184, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17559152, Length=289, Percent_Identity=29.0657439446367, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17555620, Length=480, Percent_Identity=22.9166666666667, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI32565180, Length=318, Percent_Identity=27.3584905660377, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323282, Length=301, Percent_Identity=28.2392026578073, Blast_Score=124, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325148, Length=485, Percent_Identity=22.8865979381443, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24662575, Length=258, Percent_Identity=36.8217054263566, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI22024280, Length=327, Percent_Identity=29.3577981651376, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI18859849, Length=253, Percent_Identity=27.6679841897233, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 68098; Mature: 67967

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPACARNCSASATRKPREVPVPLRYPFVIVSAPPSSAKNYRWNRVNYSRTRRVIDIWGFF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLILFYRWWDSKKWTYRSGDSEENRSRRQRMRAIWTRETMLELGPTFIKVGQLFSTRADL
HHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
FPKEYIEELSRLQDEVPAFPYEQVVEIVEDQFGKPIPQVFQFFDPTPIAAASLGQVHRAQ
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHH
LHSGEDVVVKVQRPGLEKLFNVDLGILRGIAQYLQNHPRYGRGGREWVPIYDECARILMQ
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
EIDYLNEGRNADTFRRNFKDSPEICVPRVYWRYSSPRVLTLEYLPGIKISNYEALEAAGL
HHHHHHCCCCHHHHHHCCCCCCCCCCCHHEEEECCCCEEEEECCCCCEECCCHHHHHCCC
DRRSLARIGARSYLQQLLNDGFFHADPHPGNIAVRHDGALIFYDFGMMGHIQPGTKEKLM
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCEEEEEECCCCCCCCCCHHHHHH
DTFLGVAQSDADKVIDSLIELGAIKKSADRVPIRRSIEFLLTNFVNQPYNLQSFNFAELT
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DDIYEMAYEQPFRFPATFTFVLRAVSTLEGLGKGLDPDFNFMDVAQPFADQLMAVNSEFG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
MRELFNQLGQQVGQVSSMTVNLPRRIEQTLERADRGELRVRTKSIETERLLKRLNSAAIG
HHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHH
GIYSVLLAAFLICSVVLYTADHILEAIAAFGLAGLLSFALGRVLLRLQRIDTDLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PACARNCSASATRKPREVPVPLRYPFVIVSAPPSSAKNYRWNRVNYSRTRRVIDIWGFF
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LLILFYRWWDSKKWTYRSGDSEENRSRRQRMRAIWTRETMLELGPTFIKVGQLFSTRADL
HHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
FPKEYIEELSRLQDEVPAFPYEQVVEIVEDQFGKPIPQVFQFFDPTPIAAASLGQVHRAQ
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHH
LHSGEDVVVKVQRPGLEKLFNVDLGILRGIAQYLQNHPRYGRGGREWVPIYDECARILMQ
HCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
EIDYLNEGRNADTFRRNFKDSPEICVPRVYWRYSSPRVLTLEYLPGIKISNYEALEAAGL
HHHHHHCCCCHHHHHHCCCCCCCCCCCHHEEEECCCCEEEEECCCCCEECCCHHHHHCCC
DRRSLARIGARSYLQQLLNDGFFHADPHPGNIAVRHDGALIFYDFGMMGHIQPGTKEKLM
CHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEECCEEEEEECCCCCCCCCCHHHHHH
DTFLGVAQSDADKVIDSLIELGAIKKSADRVPIRRSIEFLLTNFVNQPYNLQSFNFAELT
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHH
DDIYEMAYEQPFRFPATFTFVLRAVSTLEGLGKGLDPDFNFMDVAQPFADQLMAVNSEFG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
MRELFNQLGQQVGQVSSMTVNLPRRIEQTLERADRGELRVRTKSIETERLLKRLNSAAIG
HHHHHHHHHHHHCCHHHHEECCHHHHHHHHHHCCCCCEEEEHHHCCHHHHHHHHHHHHHH
GIYSVLLAAFLICSVVLYTADHILEAIAAFGLAGLLSFALGRVLLRLQRIDTDLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]