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The map label for this gene is secD [H]

Identifier: 37523735

GI number: 37523735

Start: 4364382

End: 4365647

Strand: Direct

Name: secD [H]

Synonym: gvip549

Alternate gene names: 37523735

Gene position: 4364382-4365647 (Clockwise)

Preceding gene: 37523734

Following gene: 37523736

Centisome position: 93.68

GC content: 62.24

Gene sequence:

>1266_bases
ATGCGTCAAAGAACTTTATTGCTGCTCCTGGTTGCGGTCGTCATCGTCGGCTCGATTTTGATCGTGGCCACCCGGCCGAC
GGTGCTGGGTCTCGACTTGCAGGGGGGTAGCCAGTTGACGCTGCTGGCCAAACCCACCGACAAAGTCAAAACGATCGACC
AGGAAGTGATGAAAGGCGTCGCCGCCGTCGTCGAGCAGCGGGTCAACGGGCTCGGGGTCTCGGAGGCCGTCGTGCAGCTC
AAAGGCAGCGACCAGATCCTGGTGCAGCTTCCCGGCGTCAAAGATCCCACCCAGGCCGAGCGGCTTCTGGGCGACACCGC
CCAGCTCGAATTTCGCAAAGAAGCGCCCAACGGCGAATTCGAAAAGACCGATCTGACCGGCGCGGATCTGACCAACGCCT
TTCCCCAGGCGCTGCAGAGCGGCAACGGCTGGGAGGTGGCCCTCGAATTTACCGGTCCTGGGGGCGAAAAATTTGCCCGC
ATCACCCGCGAACTAGCCGGCACCGGCCGCCGGCTCGGCGTGTTTCTCGACGAAAAACCGATCAGTACCCCGACGGTCGG
GGTCGAATTTGTCGACCGGGGCATCACCGGCGGCAAGGCGGTGATTACCGGCAACTTCAGCGCCCAGGAGGCGAGCGAAC
TGGGCATCAAGCTCAAAGCCGGCGCCCTGCCGGTGCCCGTCGAAATTATCGAAAACCGGACGGTCAGCGCCACCCTCGGC
GCCGACTCGGTGCGCCAGAGCCTCTACACCGGCATCGCGGGCACGCTCTTGGTGTTCATCTTCATGGTGGCCTACTACCG
TCTGCCGGGACTGATCGCCGATATGGCTCTGATTATCTACGGGCTCTCCACCTTTGCCATCTTCAAGCTGATCCCGGTCA
CCCTCACCCTGCCGGGCATCGCCGGTTTCATCCTCTCCATCGGCATGGCCGTCGACGCCAACGTGCTGATCTTCGAGCGC
ACCAAAGAGGAGCTGCGCGCCGGCAAGCAGCTTTTTACCGCGGTCGAGGCCGGTTTCTCGCGAGCCTTCACAAGCATCTT
CGATAGCCACGCCACTTCGCTCATCTCCTGTGCGGTGCTTTTCTGGCTGGGCACGGGGCTGGTCAAGGGCTTCGCCCTCA
CCCTGGCCATCGGCCTCATCGTCAATTTGTTCACTTCGGTCACCTGCTCGCGCACCTTTTTGCTGACGATCTTGAATTTT
CCCGCGCTGCGCAAACCGGCGCTTTTCGGGGTTAGTGACGTTCCTGCCAAGGCGGTGCGCCCATGA

Upstream 100 bases:

>100_bases
GCGGACAGAGCGGCTGGTCGAGGAACTGGGCCGGCCGGGCTAGCTGGCCGGGCCGATCCACAGAACGCTAGGATAAAGTG
CGTTACCGTTGCGCCCTGCT

Downstream 100 bases:

>100_bases
AAATTGAAGTCGCCAAGAGCAAGTCCAAGTGGTTTACCGCCTCCGGCATCGGACTGGGTATCGGTCTTGTCGCCATGGTC
ATTTCGCTGCTCACCCTGGG

Product: protein-export membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MRQRTLLLLLVAVVIVGSILIVATRPTVLGLDLQGGSQLTLLAKPTDKVKTIDQEVMKGVAAVVEQRVNGLGVSEAVVQL
KGSDQILVQLPGVKDPTQAERLLGDTAQLEFRKEAPNGEFEKTDLTGADLTNAFPQALQSGNGWEVALEFTGPGGEKFAR
ITRELAGTGRRLGVFLDEKPISTPTVGVEFVDRGITGGKAVITGNFSAQEASELGIKLKAGALPVPVEIIENRTVSATLG
ADSVRQSLYTGIAGTLLVFIFMVAYYRLPGLIADMALIIYGLSTFAIFKLIPVTLTLPGIAGFILSIGMAVDANVLIFER
TKEELRAGKQLFTAVEAGFSRAFTSIFDSHATSLISCAVLFWLGTGLVKGFALTLAIGLIVNLFTSVTCSRTFLLTILNF
PALRKPALFGVSDVPAKAVRP

Sequences:

>Translated_421_residues
MRQRTLLLLLVAVVIVGSILIVATRPTVLGLDLQGGSQLTLLAKPTDKVKTIDQEVMKGVAAVVEQRVNGLGVSEAVVQL
KGSDQILVQLPGVKDPTQAERLLGDTAQLEFRKEAPNGEFEKTDLTGADLTNAFPQALQSGNGWEVALEFTGPGGEKFAR
ITRELAGTGRRLGVFLDEKPISTPTVGVEFVDRGITGGKAVITGNFSAQEASELGIKLKAGALPVPVEIIENRTVSATLG
ADSVRQSLYTGIAGTLLVFIFMVAYYRLPGLIADMALIIYGLSTFAIFKLIPVTLTLPGIAGFILSIGMAVDANVLIFER
TKEELRAGKQLFTAVEAGFSRAFTSIFDSHATSLISCAVLFWLGTGLVKGFALTLAIGLIVNLFTSVTCSRTFLLTILNF
PALRKPALFGVSDVPAKAVRP
>Mature_421_residues
MRQRTLLLLLVAVVIVGSILIVATRPTVLGLDLQGGSQLTLLAKPTDKVKTIDQEVMKGVAAVVEQRVNGLGVSEAVVQL
KGSDQILVQLPGVKDPTQAERLLGDTAQLEFRKEAPNGEFEKTDLTGADLTNAFPQALQSGNGWEVALEFTGPGGEKFAR
ITRELAGTGRRLGVFLDEKPISTPTVGVEFVDRGITGGKAVITGNFSAQEASELGIKLKAGALPVPVEIIENRTVSATLG
ADSVRQSLYTGIAGTLLVFIFMVAYYRLPGLIADMALIIYGLSTFAIFKLIPVTLTLPGIAGFILSIGMAVDANVLIFER
TKEELRAGKQLFTAVEAGFSRAFTSIFDSHATSLISCAVLFWLGTGLVKGFALTLAIGLIVNLFTSVTCSRTFLLTILNF
PALRKPALFGVSDVPAKAVRP

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=428, Percent_Identity=33.1775700934579, Blast_Score=209, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 44731; Mature: 44731

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQRTLLLLLVAVVIVGSILIVATRPTVLGLDLQGGSQLTLLAKPTDKVKTIDQEVMKGV
CCCHHHHHHHHHHHHHHHEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AAVVEQRVNGLGVSEAVVQLKGSDQILVQLPGVKDPTQAERLLGDTAQLEFRKEAPNGEF
HHHHHHHHCCCCHHHHHEEECCCCEEEEEECCCCCHHHHHHHHCCHHHEEEEECCCCCCC
EKTDLTGADLTNAFPQALQSGNGWEVALEFTGPGGEKFARITRELAGTGRRLGVFLDEKP
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCC
ISTPTVGVEFVDRGITGGKAVITGNFSAQEASELGIKLKAGALPVPVEIIENRTVSATLG
CCCCCCCHHHHHCCCCCCCEEEECCCCHHHHHHCCEEEECCCCCCCHHHHCCCEEEEECC
ADSVRQSLYTGIAGTLLVFIFMVAYYRLPGLIADMALIIYGLSTFAIFKLIPVTLTLPGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
AGFILSIGMAVDANVLIFERTKEELRAGKQLFTAVEAGFSRAFTSIFDSHATSLISCAVL
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLGTGLVKGFALTLAIGLIVNLFTSVTCSRTFLLTILNFPALRKPALFGVSDVPAKAVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
P
C
>Mature Secondary Structure
MRQRTLLLLLVAVVIVGSILIVATRPTVLGLDLQGGSQLTLLAKPTDKVKTIDQEVMKGV
CCCHHHHHHHHHHHHHHHEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHH
AAVVEQRVNGLGVSEAVVQLKGSDQILVQLPGVKDPTQAERLLGDTAQLEFRKEAPNGEF
HHHHHHHHCCCCHHHHHEEECCCCEEEEEECCCCCHHHHHHHHCCHHHEEEEECCCCCCC
EKTDLTGADLTNAFPQALQSGNGWEVALEFTGPGGEKFARITRELAGTGRRLGVFLDEKP
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCC
ISTPTVGVEFVDRGITGGKAVITGNFSAQEASELGIKLKAGALPVPVEIIENRTVSATLG
CCCCCCCHHHHHCCCCCCCEEEECCCCHHHHHHCCEEEECCCCCCCHHHHCCCEEEEECC
ADSVRQSLYTGIAGTLLVFIFMVAYYRLPGLIADMALIIYGLSTFAIFKLIPVTLTLPGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
AGFILSIGMAVDANVLIFERTKEELRAGKQLFTAVEAGFSRAFTSIFDSHATSLISCAVL
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FWLGTGLVKGFALTLAIGLIVNLFTSVTCSRTFLLTILNFPALRKPALFGVSDVPAKAVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]