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The map label for this gene is hflX [H]

Identifier: 37523711

GI number: 37523711

Start: 4341864

End: 4343624

Strand: Direct

Name: hflX [H]

Synonym: glr4142

Alternate gene names: 37523711

Gene position: 4341864-4343624 (Clockwise)

Preceding gene: 37523710

Following gene: 37523713

Centisome position: 93.19

GC content: 64.96

Gene sequence:

>1761_bases
GTGGCCATCGATTCCACGATTACCGCTTTCAGAGAACCAGCCATAGACAAAATCTACGGTCCGCACAAAGGTCTCAAGCC
TGCCCAACTAAGGCAACTCAGCCGCCTGTACAGCCGGCCGTTCCCCGTGAACCGCTTTTTGAGCCCTGAGTTTGCTGAGC
GGCTGGCCGCCCTGAGTGCGGAGCTGGAGACGCCCCTGTGCGTCTACGCCAACCGCAGAGGCCAGGTGGTGCGCGTCGGT
GTCGGCACCCCCAAAGAAACCCAATTTTCGCCGGACGAACTGCCGCGCCAGGGTGCCGAGCGCCTGAGCGGCCTGCGCTG
CGTGGCGACCCGCCTCGATGGCGACGGCCCCAGCCGCGGCGATCTCACCGCCCTTGCCCTGCAGCGGCTCGACGCGCTGG
TGATTCTCGATGTGGCCATCCAGGGCTATCGGCGCCAGGGCGGCGGGCTGAGCGGCTTTGTCCAGCGCGTGCACATCGCC
AACCTGGTGCCGGACCCGCTCGCCAAGTGGGTAGTCTCGACGCCCCAACCGCTGGGCCAGGTGAGCAACCAGGACTTTGA
CGAATTTCTAGGCGATCTCGAAGACGAATTTCGCCGGGAGTGGACGGCGCGGGTAGTCGAGAGCGACCGCGAGCGGGTGC
TGCTCATCGACTTTTTCTCGACGCGCACCAGCCAGCGCGCCATGGAAGAAGAACTCTCCGAACTGGTGCAACTGGTCACC
AGTGCAGGCGGCGAGGTACTCAAAGTCTTTTACCAGCGCCGTGAACAGCCCGACCCCTCGACTTTGATCGGTCGGGGCAA
ACTCGAAGAAGTAGCCCTGAGCGTCCAGGAACTGGGGGCCAATCTGGTCGTCTGCGGACGCGAACTGACCTCCAGCCAGG
CGCGCAACCTGGAACTCGCCCTGGGGGTGCGCGTGGTGGACCGTACCGAACTGATTCTCGATATTTTTGCCCGCCGCGCC
CGCTCCCACGAGGGCAAGCTGCAGGTGGAACTGGCCCAGTTGCAATATCTGATGCCGCGCCTGACGGGCAAGGGCGAGGC
CCTCTCGCGCTTGGGCGGCGGCATCGGCACCCGCGGCCCCGGTGAAACAAAACTGGAGACCGACCGGCGGGTGATCCGCC
GCCGGATCGCCAAATTGCAGGGCGAAGTGGATGACCTTCAGGCCCACCGCGCCCGCATGCGCGCCCGCCGCCAGCGCAAG
GAAGTGCCCGTCTTCGCCCTGGTGGGCTATACCAACGCCGGCAAATCGACCCTGCTCAACGCCCTCACCGGCGCCGGAAC
CCTGGTGGCGGACCAACTGTTTGCCACCCTCGATCCGACCACGCGCCGCCTGGAGTTGCCCACCGGCGACGCGGTGCTGC
TCACAGACACGGTCGGCTTCGTCCACGATCTGCCGCCGCAGCTCATCGACGCCTTTCGGGCCACCCTCGAAGAAGTCACC
GAGGCCGACGCCCTGCTGCACGTGGTCGATCTGTCCAACCCGGCCTGGATGAACCATATCCAGGCGGTGCAGCACATCCT
CGAAAGCCTGCCCATCGCCACCGGACCGCAACTATTGGTCTTCAACAAAGTCGACCGGGTCAGCTCCCAGGTACGCGCCT
TCGCCGAGCAGGAATATCCCCTCGCGATCTTCATCTCCGCCAAGAACGGCTGGGGATTTTTGGCGCTGCGCGAGGCGCTC
ACCCGCTGGATGCGTTCGCTGAGTGATTTATGGCCGCCCATGGCCGAATCGGGCACAGGCGGCGAAACGGACCTCAATTA
A

Upstream 100 bases:

>100_bases
TAAAAAATTGACGGTAGCGCGACCGCATTTTTGCGCGATCAACGATATCGACCAACACACCTCAATACCCTGGGGATCGC
CTCGGTGAGGTGGTTATAAT

Downstream 100 bases:

>100_bases
ATTCGAGAATCTCGTCTTCGCTGATCTCGCTTTCTTCGAGCAACGCGAGGGCGGGACGGGCTTTCTCGCGCGCCAGGCGG
TACTGCTGGCGCAGTTTGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MAIDSTITAFREPAIDKIYGPHKGLKPAQLRQLSRLYSRPFPVNRFLSPEFAERLAALSAELETPLCVYANRRGQVVRVG
VGTPKETQFSPDELPRQGAERLSGLRCVATRLDGDGPSRGDLTALALQRLDALVILDVAIQGYRRQGGGLSGFVQRVHIA
NLVPDPLAKWVVSTPQPLGQVSNQDFDEFLGDLEDEFRREWTARVVESDRERVLLIDFFSTRTSQRAMEEELSELVQLVT
SAGGEVLKVFYQRREQPDPSTLIGRGKLEEVALSVQELGANLVVCGRELTSSQARNLELALGVRVVDRTELILDIFARRA
RSHEGKLQVELAQLQYLMPRLTGKGEALSRLGGGIGTRGPGETKLETDRRVIRRRIAKLQGEVDDLQAHRARMRARRQRK
EVPVFALVGYTNAGKSTLLNALTGAGTLVADQLFATLDPTTRRLELPTGDAVLLTDTVGFVHDLPPQLIDAFRATLEEVT
EADALLHVVDLSNPAWMNHIQAVQHILESLPIATGPQLLVFNKVDRVSSQVRAFAEQEYPLAIFISAKNGWGFLALREAL
TRWMRSLSDLWPPMAESGTGGETDLN

Sequences:

>Translated_586_residues
MAIDSTITAFREPAIDKIYGPHKGLKPAQLRQLSRLYSRPFPVNRFLSPEFAERLAALSAELETPLCVYANRRGQVVRVG
VGTPKETQFSPDELPRQGAERLSGLRCVATRLDGDGPSRGDLTALALQRLDALVILDVAIQGYRRQGGGLSGFVQRVHIA
NLVPDPLAKWVVSTPQPLGQVSNQDFDEFLGDLEDEFRREWTARVVESDRERVLLIDFFSTRTSQRAMEEELSELVQLVT
SAGGEVLKVFYQRREQPDPSTLIGRGKLEEVALSVQELGANLVVCGRELTSSQARNLELALGVRVVDRTELILDIFARRA
RSHEGKLQVELAQLQYLMPRLTGKGEALSRLGGGIGTRGPGETKLETDRRVIRRRIAKLQGEVDDLQAHRARMRARRQRK
EVPVFALVGYTNAGKSTLLNALTGAGTLVADQLFATLDPTTRRLELPTGDAVLLTDTVGFVHDLPPQLIDAFRATLEEVT
EADALLHVVDLSNPAWMNHIQAVQHILESLPIATGPQLLVFNKVDRVSSQVRAFAEQEYPLAIFISAKNGWGFLALREAL
TRWMRSLSDLWPPMAESGTGGETDLN
>Mature_585_residues
AIDSTITAFREPAIDKIYGPHKGLKPAQLRQLSRLYSRPFPVNRFLSPEFAERLAALSAELETPLCVYANRRGQVVRVGV
GTPKETQFSPDELPRQGAERLSGLRCVATRLDGDGPSRGDLTALALQRLDALVILDVAIQGYRRQGGGLSGFVQRVHIAN
LVPDPLAKWVVSTPQPLGQVSNQDFDEFLGDLEDEFRREWTARVVESDRERVLLIDFFSTRTSQRAMEEELSELVQLVTS
AGGEVLKVFYQRREQPDPSTLIGRGKLEEVALSVQELGANLVVCGRELTSSQARNLELALGVRVVDRTELILDIFARRAR
SHEGKLQVELAQLQYLMPRLTGKGEALSRLGGGIGTRGPGETKLETDRRVIRRRIAKLQGEVDDLQAHRARMRARRQRKE
VPVFALVGYTNAGKSTLLNALTGAGTLVADQLFATLDPTTRRLELPTGDAVLLTDTVGFVHDLPPQLIDAFRATLEEVTE
ADALLHVVDLSNPAWMNHIQAVQHILESLPIATGPQLLVFNKVDRVSSQVRAFAEQEYPLAIFISAKNGWGFLALREALT
RWMRSLSDLWPPMAESGTGGETDLN

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=230, Percent_Identity=37.3913043478261, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=38.1818181818182, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI310124269, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310124267, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310124171, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI310124169, Length=206, Percent_Identity=39.3203883495146, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1790615, Length=353, Percent_Identity=45.6090651558074, Blast_Score=282, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17561038, Length=286, Percent_Identity=32.5174825174825, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24650079, Length=325, Percent_Identity=34.7692307692308, Blast_Score=139, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 64891; Mature: 64760

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDSTITAFREPAIDKIYGPHKGLKPAQLRQLSRLYSRPFPVNRFLSPEFAERLAALSA
CCCCHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ELETPLCVYANRRGQVVRVGVGTPKETQFSPDELPRQGAERLSGLRCVATRLDGDGPSRG
HCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
DLTALALQRLDALVILDVAIQGYRRQGGGLSGFVQRVHIANLVPDPLAKWVVSTPQPLGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHH
VSNQDFDEFLGDLEDEFRREWTARVVESDRERVLLIDFFSTRTSQRAMEEELSELVQLVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHH
SAGGEVLKVFYQRREQPDPSTLIGRGKLEEVALSVQELGANLVVCGRELTSSQARNLELA
HCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCEEEE
LGVRVVDRTELILDIFARRARSHEGKLQVELAQLQYLMPRLTGKGEALSRLGGGIGTRGP
ECEEEHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
GETKLETDRRVIRRRIAKLQGEVDDLQAHRARMRARRQRKEVPVFALVGYTNAGKSTLLN
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
ALTGAGTLVADQLFATLDPTTRRLELPTGDAVLLTDTVGFVHDLPPQLIDAFRATLEEVT
HHHCCHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHH
EADALLHVVDLSNPAWMNHIQAVQHILESLPIATGPQLLVFNKVDRVSSQVRAFAEQEYP
HHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCC
LAIFISAKNGWGFLALREALTRWMRSLSDLWPPMAESGTGGETDLN
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AIDSTITAFREPAIDKIYGPHKGLKPAQLRQLSRLYSRPFPVNRFLSPEFAERLAALSA
CCCHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ELETPLCVYANRRGQVVRVGVGTPKETQFSPDELPRQGAERLSGLRCVATRLDGDGPSRG
HCCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCC
DLTALALQRLDALVILDVAIQGYRRQGGGLSGFVQRVHIANLVPDPLAKWVVSTPQPLGQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHH
VSNQDFDEFLGDLEDEFRREWTARVVESDRERVLLIDFFSTRTSQRAMEEELSELVQLVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCHHHHHHHHHHHHHHHHHH
SAGGEVLKVFYQRREQPDPSTLIGRGKLEEVALSVQELGANLVVCGRELTSSQARNLELA
HCCHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCEEEE
LGVRVVDRTELILDIFARRARSHEGKLQVELAQLQYLMPRLTGKGEALSRLGGGIGTRGP
ECEEEHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
GETKLETDRRVIRRRIAKLQGEVDDLQAHRARMRARRQRKEVPVFALVGYTNAGKSTLLN
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
ALTGAGTLVADQLFATLDPTTRRLELPTGDAVLLTDTVGFVHDLPPQLIDAFRATLEEVT
HHHCCHHHHHHHHHHHCCCCCCEEECCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHH
EADALLHVVDLSNPAWMNHIQAVQHILESLPIATGPQLLVFNKVDRVSSQVRAFAEQEYP
HHHHHEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCC
LAIFISAKNGWGFLALREALTRWMRSLSDLWPPMAESGTGGETDLN
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]