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The map label for this gene is phoB [C]

Identifier: 37523697

GI number: 37523697

Start: 4324532

End: 4325236

Strand: Direct

Name: phoB [C]

Synonym: glr4128

Alternate gene names: 37523697

Gene position: 4324532-4325236 (Clockwise)

Preceding gene: 37523690

Following gene: 37523698

Centisome position: 92.82

GC content: 62.13

Gene sequence:

>705_bases
ATGGATGCAACGATGCGCCACCAGACGGTACTGGTGGTCGACGACGCAGAACTCATCCGCGAAACGGTGGGCATGGCCCT
TGGCGAGGAAGGCTACAGCGTCGTGCTGGCCGAGGACGGCCGCCAGGCGCTCGATTTGGTCCGCAACTCCGATAAAGTCG
ATTTGATCGTGCTCGACTTGATGTTGCCCCATCTCAACGGCCTTGATCTGTGCCGTTTGCTGCGCCGCGAGGGTAACGCC
GTGCCGATTTTGATGCTCACCGCCAAGGGCACCGAGACCGACCGGGTCGTGGGCCTCGAAGTGGGTGCCGACGACTATCT
ACCCAAGCCCTTTGGGATGCGCGAGCTGATTGCCCGCTGCCGGGCGGTGCTGCGCCGCCATACCCGCACCCAGACCCAGG
ACAACAGCGCTGTCCTGCGCTGCGGCGATCTGTGCATGAATACGCAAGAGTGCCGGGTGCGCGTGCGCGACGTCGAAGTC
GATCTTTCTCCTAAAGAATTTCGTCTGTTGGAACTATTCATGCGCAACCCGCGCCGGGTATGGTCGCGCGAGCAGCTCAT
CGAGCGGGTCTGGGGACCGGATTTCATGGGCGACAGCAAAACCGTCGATGTCCATATTCGCTGGCTGCGCGAGAAGCTCG
AGGCCGATCCCAGCCATCCCGAATATCTGGTGACGGTGCGGGGCTTCGGCTACCGCTTCGGCTAA

Upstream 100 bases:

>100_bases
CAATGGGCTCCCCACTCTAGACTACAGCACCTTCCCCCCCAAGCAGTCTTGAGCGCTTCGCGCCGGATGGTAGGATGATG
TCGCTCCCAGAGGAACAGGC

Downstream 100 bases:

>100_bases
AGCATCGCCAATACAGGACGGCTGAGGCGTCAGCCGTCGCGCAAGCTACCGCTCCGGCACTTCGGAGCGGCATGAACGCC
TGCGCACGATCCCGAAGGCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MDATMRHQTVLVVDDAELIRETVGMALGEEGYSVVLAEDGRQALDLVRNSDKVDLIVLDLMLPHLNGLDLCRLLRREGNA
VPILMLTAKGTETDRVVGLEVGADDYLPKPFGMRELIARCRAVLRRHTRTQTQDNSAVLRCGDLCMNTQECRVRVRDVEV
DLSPKEFRLLELFMRNPRRVWSREQLIERVWGPDFMGDSKTVDVHIRWLREKLEADPSHPEYLVTVRGFGYRFG

Sequences:

>Translated_234_residues
MDATMRHQTVLVVDDAELIRETVGMALGEEGYSVVLAEDGRQALDLVRNSDKVDLIVLDLMLPHLNGLDLCRLLRREGNA
VPILMLTAKGTETDRVVGLEVGADDYLPKPFGMRELIARCRAVLRRHTRTQTQDNSAVLRCGDLCMNTQECRVRVRDVEV
DLSPKEFRLLELFMRNPRRVWSREQLIERVWGPDFMGDSKTVDVHIRWLREKLEADPSHPEYLVTVRGFGYRFG
>Mature_234_residues
MDATMRHQTVLVVDDAELIRETVGMALGEEGYSVVLAEDGRQALDLVRNSDKVDLIVLDLMLPHLNGLDLCRLLRREGNA
VPILMLTAKGTETDRVVGLEVGADDYLPKPFGMRELIARCRAVLRRHTRTQTQDNSAVLRCGDLCMNTQECRVRVRDVEV
DLSPKEFRLLELFMRNPRRVWSREQLIERVWGPDFMGDSKTVDVHIRWLREKLEADPSHPEYLVTVRGFGYRFG

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=43.6123348017621, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=40.9691629955947, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=39.5555555555556, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=40.0881057268723, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=39.6396396396396, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=38.3259911894273, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.0535714285714, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=34.5991561181435, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=40.9691629955947, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=37.7777777777778, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=37.7777777777778, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=36.6379310344828, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=33.7777777777778, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=28.755364806867, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790299, Length=131, Percent_Identity=29.0076335877863, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787487, Length=124, Percent_Identity=29.8387096774194, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=29.9065420560748, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=108, Percent_Identity=35.1851851851852, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26844; Mature: 26844

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATMRHQTVLVVDDAELIRETVGMALGEEGYSVVLAEDGRQALDLVRNSDKVDLIVLDL
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEEH
MLPHLNGLDLCRLLRREGNAVPILMLTAKGTETDRVVGLEVGADDYLPKPFGMRELIARC
HHCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
RAVLRRHTRTQTQDNSAVLRCGDLCMNTQECRVRVRDVEVDLSPKEFRLLELFMRNPRRV
HHHHHHHHCCCCCCCCCEEEEHHHHCCCHHHEEEEEEEEEECCHHHHHHHHHHHCCCHHH
WSREQLIERVWGPDFMGDSKTVDVHIRWLREKLEADPSHPEYLVTVRGFGYRFG
HHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MDATMRHQTVLVVDDAELIRETVGMALGEEGYSVVLAEDGRQALDLVRNSDKVDLIVLDL
CCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEEH
MLPHLNGLDLCRLLRREGNAVPILMLTAKGTETDRVVGLEVGADDYLPKPFGMRELIARC
HHCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHH
RAVLRRHTRTQTQDNSAVLRCGDLCMNTQECRVRVRDVEVDLSPKEFRLLELFMRNPRRV
HHHHHHHHCCCCCCCCCEEEEHHHHCCCHHHEEEEEEEEEECCHHHHHHHHHHHCCCHHH
WSREQLIERVWGPDFMGDSKTVDVHIRWLREKLEADPSHPEYLVTVRGFGYRFG
HHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]