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The map label for this gene is nlpI [C]

Identifier: 37523657

GI number: 37523657

Start: 4286485

End: 4287111

Strand: Reverse

Name: nlpI [C]

Synonym: gll4088

Alternate gene names: 37523657

Gene position: 4287111-4286485 (Counterclockwise)

Preceding gene: 37523660

Following gene: 37523655

Centisome position: 92.02

GC content: 59.49

Gene sequence:

>627_bases
GTGTGTCGTCGGATGAGTGCTTCTGATTGGATCAAGCGGGGGATGAAAAAGGCTCAAGCTGGCAATTACGACGGAGCTAT
CTCCGACTATACCCAGGCCATTCTACTGCAGTCGAACTGCCCCGAGGCGTACTGCGGCCGGGGTAACGCCTACTACCGCC
TCAACAACAAAATCCGGGCGCTCGAGGATTATACCCACGCCATCACCCTCAAGCCGGAATTCAGCGAAGCGTATTTCAAT
CGGGGCACCGCTCGCTCCCAACTGGGAAACAGCCAGGGGGCGCTCGAAGATTTTAGTCGGGTCGTGCACCTGAGCCCGCG
CGACGCCAAAGCCCACTTCAACTGGGGCAACGCCCACTACCGGTTAGGCCATAAGCAGGAAGCGATCGAGGGGTACTCCC
GGGCTATTCAGTTGCAGCCGGATTACGCAGAAGCCTACAGCAACCGGGGGCTGGCCCACTGCAAGATGCAGGCGGTAGGT
ACAGGGCTGCTCGATCTGCACAAAGCAGCCACCCTGTACAAAACCCAGGGCAATATGAGCCGCCACTGGCAAACCCAGCA
GACGATTGCGAAATTCCACTCCGACAGCGCCAGCGCCACCCAGGTGCGTGGAGAAAGCGCGCGCTGA

Upstream 100 bases:

>100_bases
GCACCGCCTTGGTGGTGGACACCTGGTCCACAAGTAAAGATAAACCAGAATTCGGCGGGTTTCTGATTTTTTCTGGTTAG
CGTGGAGATAGTTTCGCTGC

Downstream 100 bases:

>100_bases
AAAAGCGCGCGACTTTTTGAACCTAGCGCTGTTATACCGCCGCCGTCTCGGTCTTTTCGCTTTTGATCTTGTTGAGCAGA
CCGCCCGCCAGGATCACTTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MCRRMSASDWIKRGMKKAQAGNYDGAISDYTQAILLQSNCPEAYCGRGNAYYRLNNKIRALEDYTHAITLKPEFSEAYFN
RGTARSQLGNSQGALEDFSRVVHLSPRDAKAHFNWGNAHYRLGHKQEAIEGYSRAIQLQPDYAEAYSNRGLAHCKMQAVG
TGLLDLHKAATLYKTQGNMSRHWQTQQTIAKFHSDSASATQVRGESAR

Sequences:

>Translated_208_residues
MCRRMSASDWIKRGMKKAQAGNYDGAISDYTQAILLQSNCPEAYCGRGNAYYRLNNKIRALEDYTHAITLKPEFSEAYFN
RGTARSQLGNSQGALEDFSRVVHLSPRDAKAHFNWGNAHYRLGHKQEAIEGYSRAIQLQPDYAEAYSNRGLAHCKMQAVG
TGLLDLHKAATLYKTQGNMSRHWQTQQTIAKFHSDSASATQVRGESAR
>Mature_208_residues
MCRRMSASDWIKRGMKKAQAGNYDGAISDYTQAILLQSNCPEAYCGRGNAYYRLNNKIRALEDYTHAITLKPEFSEAYFN
RGTARSQLGNSQGALEDFSRVVHLSPRDAKAHFNWGNAHYRLGHKQEAIEGYSRAIQLQPDYAEAYSNRGLAHCKMQAVG
TGLLDLHKAATLYKTQGNMSRHWQTQQTIAKFHSDSASATQVRGESAR

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=138, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI32307148, Length=138, Percent_Identity=32.6086956521739, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115532690, Length=102, Percent_Identity=38.2352941176471, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=102, Percent_Identity=38.2352941176471, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17647755, Length=96, Percent_Identity=39.5833333333333, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24585827, Length=96, Percent_Identity=39.5833333333333, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24585829, Length=96, Percent_Identity=39.5833333333333, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 23353; Mature: 23353

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRRMSASDWIKRGMKKAQAGNYDGAISDYTQAILLQSNCPEAYCGRGNAYYRLNNKIRA
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCHHHHCCCCEEEEECCCHHH
LEDYTHAITLKPEFSEAYFNRGTARSQLGNSQGALEDFSRVVHLSPRDAKAHFNWGNAHY
HHCCCEEEEECCCHHHHHHCCCCHHHHCCCCCCHHHHHHHHEECCCCCCCEEECCCCCEE
RLGHKQEAIEGYSRAIQLQPDYAEAYSNRGLAHCKMQAVGTGLLDLHKAATLYKTQGNMS
ECCCHHHHHHHHHHEEEECCCHHHHHCCCCHHEEEHHHHCCCHHHHHHHHHHHCCCCCCH
RHWQTQQTIAKFHSDSASATQVRGESAR
HHHHHHHHHHHHHCCCCCHHHCCCCCCC
>Mature Secondary Structure
MCRRMSASDWIKRGMKKAQAGNYDGAISDYTQAILLQSNCPEAYCGRGNAYYRLNNKIRA
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCHHHHCCCCEEEEECCCHHH
LEDYTHAITLKPEFSEAYFNRGTARSQLGNSQGALEDFSRVVHLSPRDAKAHFNWGNAHY
HHCCCEEEEECCCHHHHHHCCCCHHHHCCCCCCHHHHHHHHEECCCCCCCEEECCCCCEE
RLGHKQEAIEGYSRAIQLQPDYAEAYSNRGLAHCKMQAVGTGLLDLHKAATLYKTQGNMS
ECCCHHHHHHHHHHEEEECCCHHHHHCCCCHHEEEHHHHCCCHHHHHHHHHHHCCCCCCH
RHWQTQQTIAKFHSDSASATQVRGESAR
HHHHHHHHHHHHHCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]