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The map label for this gene is 37523627

Identifier: 37523627

GI number: 37523627

Start: 4253292

End: 4254383

Strand: Direct

Name: 37523627

Synonym: glr4058

Alternate gene names: NA

Gene position: 4253292-4254383 (Clockwise)

Preceding gene: 37523626

Following gene: 37523630

Centisome position: 91.29

GC content: 62.36

Gene sequence:

>1092_bases
ATGCAAGGTACCCATGGGGCAACCGGGGGTCAAAAATCTGCTTTGCTGTTTTGCAACGCAATTCTTCCCCGAGTCTCCAG
GACTTTCGCGATTAGCATCCGCTTTTTACCGGGTCGACTGGGCAGGGCTGTCCTCACCGCTTACTTGCTGTGCCGGATAG
CCGACACGATCGAAGACGATCCGGCGGCGAGCGCGGGCGAGAAGGTGCGGCTTTTGGGCGAATTTATGGCGGGTTTTGAC
GAGGTTGAGACAGCCAGGAAGTTTCCGACTCTGGCGCAATCGGTGAGCGGCGAGGCGGCCCACGTCGAGCTGGTCCACCA
CACCGATTTGGTCTTCGAGTTGTTCGAGGGCGTACCCGCTCCTTCGCGCCAAATCGTCAAGCGCTGGGTGGGCGAGATGG
TCGAAGGGATGCAGAAGTTTGTCGCCCTTTATCCCCACGGCATCCGCATCCAGACGCTCGAAGAATACAACGAATACTGC
TATTACGTCGCAGGAACGGTAGGGCATCTGCTCACCGACCTGTGGCATGCCCACGCCCCAAGCGTCGATCGGGCCAAGTA
CACGGCTCTGCTCGAGCATTGCGAGGCCTTCGGCGAGGCGCTCCAGACGGTCAATATTCTCAAGGACATCGCCTGGGACG
CCGAGCACGAAAATTCGATCTATGTGCCTGAGCAATCGCTGCGCGAGCACGGCAGCAGCCAGCAGACCCTGCTCAGCCCG
CACTGTCTTGAGCAGAACCGGGCGGCAATCGCCTCGCTGGTGGCGCTGGCCTGGGCGGATCTCGACGCCGCCCTCGTCTA
TTTGCTTGCCATCCCCCGGCGGGCCGTGCCGATTCGTCTGTTCTGCATCCTGCCGTTGCTGTTCGCCTACGCCACGCTGC
GCGAGATTACCCGCTCGACGGCGATGCTCACCAGCGGCGGCACCGTCAAAATCTCGCGCGAAGAGGTCAAAGCGCTGATG
GTGGCCGGAGTGGCCACCATCTTGAGCAATCGCGGGATTGAGCGGCTGGTTGCGCGGGTGCGCGCCGACACTTATGGGCT
GGGGTGGGGGGGATCCCCCCCCTGCCCCCCCCTTGGGAAGGGGGGGTCGTGA

Upstream 100 bases:

>100_bases
TGAGGTGGTTGAGCGAAGGTCGGGTATGCGCGCGATCAGATAACAAATCCGGTAAGCTCATCGTAAAATTCCTAGATGGT
GTGTGCAGGGGTGAAGAACA

Downstream 100 bases:

>100_bases
GGCGCCGCGGCGGCCCGGGTGCCCGGGCCGCCTTAAACTGTGGCCGATGAGGCTGGGGCGAGCAGTTCGATGGGCAGGCC
GTCGGGGTCTACTACAAAGG

Product: farnesyl-diphosphate farnesyltransferase

Products: NA

Alternate protein names: Farnesyl-Diphosphate Farnesyltransferase; Squalene Synthase; Squalene/Phytoene Synthase Family Protein; Squalene And Phytoene Synthase; Phytoene/Squalene Synthetase Family Protein; Squalene/Phytoene Synthase-Like Protein; Phytoene/Squalene Synthetase; SQS PSY Squalene/Phytoene Synthase-Like Protein

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQGTHGATGGQKSALLFCNAILPRVSRTFAISIRFLPGRLGRAVLTAYLLCRIADTIEDDPAASAGEKVRLLGEFMAGFD
EVETARKFPTLAQSVSGEAAHVELVHHTDLVFELFEGVPAPSRQIVKRWVGEMVEGMQKFVALYPHGIRIQTLEEYNEYC
YYVAGTVGHLLTDLWHAHAPSVDRAKYTALLEHCEAFGEALQTVNILKDIAWDAEHENSIYVPEQSLREHGSSQQTLLSP
HCLEQNRAAIASLVALAWADLDAALVYLLAIPRRAVPIRLFCILPLLFAYATLREITRSTAMLTSGGTVKISREEVKALM
VAGVATILSNRGIERLVARVRADTYGLGWGGSPPCPPLGKGGS

Sequences:

>Translated_363_residues
MQGTHGATGGQKSALLFCNAILPRVSRTFAISIRFLPGRLGRAVLTAYLLCRIADTIEDDPAASAGEKVRLLGEFMAGFD
EVETARKFPTLAQSVSGEAAHVELVHHTDLVFELFEGVPAPSRQIVKRWVGEMVEGMQKFVALYPHGIRIQTLEEYNEYC
YYVAGTVGHLLTDLWHAHAPSVDRAKYTALLEHCEAFGEALQTVNILKDIAWDAEHENSIYVPEQSLREHGSSQQTLLSP
HCLEQNRAAIASLVALAWADLDAALVYLLAIPRRAVPIRLFCILPLLFAYATLREITRSTAMLTSGGTVKISREEVKALM
VAGVATILSNRGIERLVARVRADTYGLGWGGSPPCPPLGKGGS
>Mature_363_residues
MQGTHGATGGQKSALLFCNAILPRVSRTFAISIRFLPGRLGRAVLTAYLLCRIADTIEDDPAASAGEKVRLLGEFMAGFD
EVETARKFPTLAQSVSGEAAHVELVHHTDLVFELFEGVPAPSRQIVKRWVGEMVEGMQKFVALYPHGIRIQTLEEYNEYC
YYVAGTVGHLLTDLWHAHAPSVDRAKYTALLEHCEAFGEALQTVNILKDIAWDAEHENSIYVPEQSLREHGSSQQTLLSP
HCLEQNRAAIASLVALAWADLDAALVYLLAIPRRAVPIRLFCILPLLFAYATLREITRSTAMLTSGGTVKISREEVKALM
VAGVATILSNRGIERLVARVRADTYGLGWGGSPPCPPLGKGGS

Specific function: Unknown

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI67089147, Length=312, Percent_Identity=25.3205128205128, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321984, Length=300, Percent_Identity=28.3333333333333, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 39631; Mature: 39631

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGTHGATGGQKSALLFCNAILPRVSRTFAISIRFLPGRLGRAVLTAYLLCRIADTIEDD
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
PAASAGEKVRLLGEFMAGFDEVETARKFPTLAQSVSGEAAHVELVHHTDLVFELFEGVPA
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCC
PSRQIVKRWVGEMVEGMQKFVALYPHGIRIQTLEEYNEYCYYVAGTVGHLLTDLWHAHAP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVDRAKYTALLEHCEAFGEALQTVNILKDIAWDAEHENSIYVPEQSLREHGSSQQTLLSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHCCCCCCHHCCC
HCLEQNRAAIASLVALAWADLDAALVYLLAIPRRAVPIRLFCILPLLFAYATLREITRST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMLTSGGTVKISREEVKALMVAGVATILSNRGIERLVARVRADTYGLGWGGSPPCPPLGK
HHEECCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GGS
CCC
>Mature Secondary Structure
MQGTHGATGGQKSALLFCNAILPRVSRTFAISIRFLPGRLGRAVLTAYLLCRIADTIEDD
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCC
PAASAGEKVRLLGEFMAGFDEVETARKFPTLAQSVSGEAAHVELVHHTDLVFELFEGVPA
CCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCC
PSRQIVKRWVGEMVEGMQKFVALYPHGIRIQTLEEYNEYCYYVAGTVGHLLTDLWHAHAP
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SVDRAKYTALLEHCEAFGEALQTVNILKDIAWDAEHENSIYVPEQSLREHGSSQQTLLSP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCHHHHHHCCCCCCHHCCC
HCLEQNRAAIASLVALAWADLDAALVYLLAIPRRAVPIRLFCILPLLFAYATLREITRST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AMLTSGGTVKISREEVKALMVAGVATILSNRGIERLVARVRADTYGLGWGGSPPCPPLGK
HHEECCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GGS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA