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The map label for this gene is pgm [H]

Identifier: 37523552

GI number: 37523552

Start: 4184335

End: 4185969

Strand: Reverse

Name: pgm [H]

Synonym: gll3983

Alternate gene names: 37523552

Gene position: 4185969-4184335 (Counterclockwise)

Preceding gene: 37523553

Following gene: 37523551

Centisome position: 89.85

GC content: 62.32

Gene sequence:

>1635_bases
ATGGATATTAAAACCGTTGCCACGACCCCGTTCAGCGATCAGAAGCCGGGTACTTCCGGTCTGCGCAAGAAAGTGCCGGT
CTTTCAGCAGCCGCACTACTTAGAAAACTTTGTCCAGTCGATTTTCGATAGCCTGGAAGGGTATGCGGGCCAGACGCTGG
TTTTGGGGGGCGACGGCCGTTACTTCAATCGCGAAGCAATCCAGATTATCCTCAAGATCGCGGCGGCCAGCGGCTTCGGC
CGTGTGCTGGTGGGCAAGGACGGCATCTTCTCGACCCCGGCGGTCTCCTGCGTCATCCGCAAAACCGCCGCCTTCGGCGG
GATTATCCTTTCGGCGAGCCACAATCCCGCCGGCCCCCACGAAGATTTTGGCATCAAGTACAACGTCGGCAACGGCGGCC
CAGCTCCGGAGAAGGTGACCGAGGCGATTTACGCGCGCACCAAAACCATCGATCACTACCAGATCCTCGACGGCCCGGAT
GTGGATCTGGGCAAGCTCGGCACGTTCGCCCTCGGCCCGCTCACCGTCGAGGTCATCGATCCGCTCACCGACTACATCGA
ATTGATGGAATCGCTCTTTGATTTTGGGCGGATTCGGGATTTGCTCGCGGGCGGCGAATTTCGCCTGTGCGTCGACTCGA
TGCACGCGGTGACCGGTCCCTACGCCCACGCCCTGTTTGAAGACCGCCTGGGAGCCCCGGCGGGGACAGTGCACGGCGGC
ACGCCCCTCGAAGATTTTGGCGGTGGACACCCGGATCCCAATCTTGTCTATGCCCACGAACTGGTCGAGATTCTCTTTGG
CGAGGACGCGCCCGATTTTGGAGCCGCCTCCGACGGCGACGGCGATCGCAACATGATCCTAGGGCGGCACTTTTTTGTCA
CCCCCAGCGACAGCCTCGCGGTACTGGCCGCCAACGCCAAACTGGTGCCGGGTTATCAAGCCGGGCTTGCCGGGGTGGCG
CGCTCGATGCCCACCAGCCAGGCGGCCGACCGGGTGGCGGCCCAACTGGGCATCGACTGCTACGAGACGCCCACCGGCTG
GAAGTTCTTCGGCAACCTGCTCGATGCAGGCAAGGCGACCTTGTGCGGCGAAGAGAGTTTCGGCACCGGCTCAGGTCACA
TTCGCGAAAAAGACGGCCTCTGGGCAGTGCTCTTCTGGCTGAATATCCTGGCGGTGCGCCGGCAGTCGGTCGAGCAGATC
GTCCGCGAGCACTGGCAGATTTATGGGCGCAATTACTACTCGCGTCACGACTACGAAGCGGTCGATTCCGCCCAGGCCCA
GGCCCTGATCGAGCACCTGCACGCGCAGATGCCCCACCTGGCGGGCAAAGCCTTCGGAAGCTACGAGGTCGCGTACACCG
ACGACTTCAGCTATACCGATCCGGTGGACGGCAACGTGAGCAAGAACCAGGGCATCCGGGTGGGTTTCACCGACGGCTCG
CGCGTCGTCTTTCGCCTCTCGGGCACCGGCACCCAGGGGGCGACCCTTCGGGTTTACCTCGAAAGCTTCGAGCCCAACAT
CGCCAAACACAACCAAGATCCGCAGCAGGCCCTGGCGGGACTCATCACCATAGCCGAGGAACTGGCCCAGATCCGCAAGT
TCACCGGCAGGGATAAACCGACCGTGATCACCTGA

Upstream 100 bases:

>100_bases
GGTTAACGACAGGAGCCGGCCGAGCCGACCGGTACGATGATGTCATCAGGAAGCTCCGGGTCTTCCGAGCGCACCTCACT
GCCGTCTTTGTGCTACTTGC

Downstream 100 bases:

>100_bases
TTTCGGCATTGTCATCCCAAAGCGAAAACGAATAGCATGTGGACGCGCCGTTGAGAAAGTTTGGTACCGGCGATGTCCAT
GCAAACCGTGATCGGCATGC

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MDIKTVATTPFSDQKPGTSGLRKKVPVFQQPHYLENFVQSIFDSLEGYAGQTLVLGGDGRYFNREAIQIILKIAAASGFG
RVLVGKDGIFSTPAVSCVIRKTAAFGGIILSASHNPAGPHEDFGIKYNVGNGGPAPEKVTEAIYARTKTIDHYQILDGPD
VDLGKLGTFALGPLTVEVIDPLTDYIELMESLFDFGRIRDLLAGGEFRLCVDSMHAVTGPYAHALFEDRLGAPAGTVHGG
TPLEDFGGGHPDPNLVYAHELVEILFGEDAPDFGAASDGDGDRNMILGRHFFVTPSDSLAVLAANAKLVPGYQAGLAGVA
RSMPTSQAADRVAAQLGIDCYETPTGWKFFGNLLDAGKATLCGEESFGTGSGHIREKDGLWAVLFWLNILAVRRQSVEQI
VREHWQIYGRNYYSRHDYEAVDSAQAQALIEHLHAQMPHLAGKAFGSYEVAYTDDFSYTDPVDGNVSKNQGIRVGFTDGS
RVVFRLSGTGTQGATLRVYLESFEPNIAKHNQDPQQALAGLITIAEELAQIRKFTGRDKPTVIT

Sequences:

>Translated_544_residues
MDIKTVATTPFSDQKPGTSGLRKKVPVFQQPHYLENFVQSIFDSLEGYAGQTLVLGGDGRYFNREAIQIILKIAAASGFG
RVLVGKDGIFSTPAVSCVIRKTAAFGGIILSASHNPAGPHEDFGIKYNVGNGGPAPEKVTEAIYARTKTIDHYQILDGPD
VDLGKLGTFALGPLTVEVIDPLTDYIELMESLFDFGRIRDLLAGGEFRLCVDSMHAVTGPYAHALFEDRLGAPAGTVHGG
TPLEDFGGGHPDPNLVYAHELVEILFGEDAPDFGAASDGDGDRNMILGRHFFVTPSDSLAVLAANAKLVPGYQAGLAGVA
RSMPTSQAADRVAAQLGIDCYETPTGWKFFGNLLDAGKATLCGEESFGTGSGHIREKDGLWAVLFWLNILAVRRQSVEQI
VREHWQIYGRNYYSRHDYEAVDSAQAQALIEHLHAQMPHLAGKAFGSYEVAYTDDFSYTDPVDGNVSKNQGIRVGFTDGS
RVVFRLSGTGTQGATLRVYLESFEPNIAKHNQDPQQALAGLITIAEELAQIRKFTGRDKPTVIT
>Mature_544_residues
MDIKTVATTPFSDQKPGTSGLRKKVPVFQQPHYLENFVQSIFDSLEGYAGQTLVLGGDGRYFNREAIQIILKIAAASGFG
RVLVGKDGIFSTPAVSCVIRKTAAFGGIILSASHNPAGPHEDFGIKYNVGNGGPAPEKVTEAIYARTKTIDHYQILDGPD
VDLGKLGTFALGPLTVEVIDPLTDYIELMESLFDFGRIRDLLAGGEFRLCVDSMHAVTGPYAHALFEDRLGAPAGTVHGG
TPLEDFGGGHPDPNLVYAHELVEILFGEDAPDFGAASDGDGDRNMILGRHFFVTPSDSLAVLAANAKLVPGYQAGLAGVA
RSMPTSQAADRVAAQLGIDCYETPTGWKFFGNLLDAGKATLCGEESFGTGSGHIREKDGLWAVLFWLNILAVRRQSVEQI
VREHWQIYGRNYYSRHDYEAVDSAQAQALIEHLHAQMPHLAGKAFGSYEVAYTDDFSYTDPVDGNVSKNQGIRVGFTDGS
RVVFRLSGTGTQGATLRVYLESFEPNIAKHNQDPQQALAGLITIAEELAQIRKFTGRDKPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=559, Percent_Identity=57.2450805008945, Blast_Score=636, Evalue=0.0,
Organism=Homo sapiens, GI21361621, Length=563, Percent_Identity=56.6607460035524, Blast_Score=635, Evalue=0.0,
Organism=Homo sapiens, GI133922562, Length=561, Percent_Identity=51.3368983957219, Blast_Score=565, Evalue=1e-161,
Organism=Homo sapiens, GI290463104, Length=367, Percent_Identity=57.7656675749319, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=48.1481481481481, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=45.9259259259259, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17535441, Length=561, Percent_Identity=53.475935828877, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6323752, Length=567, Percent_Identity=46.5608465608466, Blast_Score=497, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6322722, Length=568, Percent_Identity=46.830985915493, Blast_Score=492, Evalue=1e-140,
Organism=Drosophila melanogaster, GI17864244, Length=563, Percent_Identity=50.4440497335702, Blast_Score=567, Evalue=1e-162,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58770; Mature: 58770

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKTVATTPFSDQKPGTSGLRKKVPVFQQPHYLENFVQSIFDSLEGYAGQTLVLGGDGR
CCCCEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YFNREAIQIILKIAAASGFGRVLVGKDGIFSTPAVSCVIRKTAAFGGIILSASHNPAGPH
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
EDFGIKYNVGNGGPAPEKVTEAIYARTKTIDHYQILDGPDVDLGKLGTFALGPLTVEVID
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCEEECCEEHHHHH
PLTDYIELMESLFDFGRIRDLLAGGEFRLCVDSMHAVTGPYAHALFEDRLGAPAGTVHGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
TPLEDFGGGHPDPNLVYAHELVEILFGEDAPDFGAASDGDGDRNMILGRHFFVTPSDSLA
CCHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEE
VLAANAKLVPGYQAGLAGVARSMPTSQAADRVAAQLGIDCYETPTGWKFFGNLLDAGKAT
EEEECCEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCE
LCGEESFGTGSGHIREKDGLWAVLFWLNILAVRRQSVEQIVREHWQIYGRNYYSRHDYEA
ECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VDSAQAQALIEHLHAQMPHLAGKAFGSYEVAYTDDFSYTDPVDGNVSKNQGIRVGFTDGS
HHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
RVVFRLSGTGTQGATLRVYLESFEPNIAKHNQDPQQALAGLITIAEELAQIRKFTGRDKP
EEEEEEECCCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVIT
CCCC
>Mature Secondary Structure
MDIKTVATTPFSDQKPGTSGLRKKVPVFQQPHYLENFVQSIFDSLEGYAGQTLVLGGDGR
CCCCEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCC
YFNREAIQIILKIAAASGFGRVLVGKDGIFSTPAVSCVIRKTAAFGGIILSASHNPAGPH
CCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCC
EDFGIKYNVGNGGPAPEKVTEAIYARTKTIDHYQILDGPDVDLGKLGTFALGPLTVEVID
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCEEECCEEHHHHH
PLTDYIELMESLFDFGRIRDLLAGGEFRLCVDSMHAVTGPYAHALFEDRLGAPAGTVHGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHCCCCCCCCCCC
TPLEDFGGGHPDPNLVYAHELVEILFGEDAPDFGAASDGDGDRNMILGRHFFVTPSDSLA
CCHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEE
VLAANAKLVPGYQAGLAGVARSMPTSQAADRVAAQLGIDCYETPTGWKFFGNLLDAGKAT
EEEECCEECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCE
LCGEESFGTGSGHIREKDGLWAVLFWLNILAVRRQSVEQIVREHWQIYGRNYYSRHDYEA
ECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
VDSAQAQALIEHLHAQMPHLAGKAFGSYEVAYTDDFSYTDPVDGNVSKNQGIRVGFTDGS
HHHHHHHHHHHHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCC
RVVFRLSGTGTQGATLRVYLESFEPNIAKHNQDPQQALAGLITIAEELAQIRKFTGRDKP
EEEEEEECCCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVIT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]