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The map label for this gene is csd [H]

Identifier: 37523519

GI number: 37523519

Start: 4145220

End: 4146356

Strand: Reverse

Name: csd [H]

Synonym: gll3950

Alternate gene names: 37523519

Gene position: 4146356-4145220 (Counterclockwise)

Preceding gene: 37523520

Following gene: 37523518

Centisome position: 89.0

GC content: 67.63

Gene sequence:

>1137_bases
ATGCTTCAAGCGTTGCGCGCTCAACTGGATCTCGACGGCCGCGTCTATTTCAACCACGGCGGGCAGGGTTTATTGCCCGA
ATCGAGTCTGGAACGCCTGATCTGGTGCTATCGCCACTGGCGGCGGTGCGGGCCATTTTCGCAGCAAGCCGAGCGGTTGG
CGGCAGAGCAGGTGCAGCGCACCCGTGAAGCACTGGCGACCCAACTGGGGGTGGCAGGCAGCACCCTCAGTTGGGCCGAA
AGCACCAGCCACAGCCTCAATATCGCCCTGTGGGGCTTGGACTGGCGCCCCGGCGACGGGCTGCTTGTCTCCGACTGCGA
GCACCCGGGAGCGCTCGCCCCCGCCTGCCGGGTGGCCGAGCGCTTCGGGCTGCAGCGGCAGAGTGTGGCGCTCTCGCCGG
CGGCGGATCCGCTCGCGGCGGTGGAGGCGGCCCTCCAACCGAATACGCGGCTGGTGCTGCTTTCGCATGTGCTCTGGAAC
AGCGGCCGGGTGCTGCCGGTGGATCAGATGACCCGGCTTTGCCGCGAGCGGGGGGTGCTGGTGCTCTGGGACGGTGCCCA
GGGAGCGGGCGTGCTGCCCCTCGATTACTCCCAGGTCGACTTGTACGCCTCCACCTGCCACAAATGGTGGATGGGTCCGG
CGGGCACGGGGTTTCTCTACGTCAGCGAGCGGGTGCGTCCTCGTTTGCAACCGACCTACGTCGGCTGGCGCAGTGCCGAG
CGCTATTGGCCGGATCCGGTCTGGTATCCGGACGGCCGCGCCTTCGAGGTGGCGACGATCCCAGTCGAGTTGCTCGCAGC
GCTTGAGCAGTCGCTTGCGCTGCACGCCCAGGCGGGATCCGCCGACCTGCGCGCCCGGGCCATCCGGGATCTGGCCGGGC
AGTTGTGGGAAAGGCTCAAAGCCGACCCGCAGGTGGAACTGTTGGCCGAGCAACCGCCGGAGGCGGGACTGGTGTGCTGG
CGCCCAAAAAGGGCGCTCACCTTCGCCGATCTCAGAAGTCGGGTGCAGTGGCTCGAAGCGCGTGGAATCTTTGTGCGGGC
CATTCCCCAGCCGCTGTGTCTGCGCGCCTCGGTGCACTACTTCAACACAACCGGGGAGATCGCCGCACTGCTTGAGGCGC
TCGAGCGGCTCGATTGA

Upstream 100 bases:

>100_bases
TCCCACCAGTGATTCGGGCAATTGAGCGCAGAGCGTTTCCGGCCCGGCGGCGACTGCCGGGCCGGATGCGCTATCCTGCC
AGAGCAGAGGTGGGTTTGCC

Downstream 100 bases:

>100_bases
TCCGGGCGCGCGGTTGCCTGGGTCGGACAGATGCCCTTTGATGGGAGGAGTGTATTGTTGACCGACGATGGGCAAGCGTT
CTTTGCAATCTTCAAAACGA

Product: L-cysteine/cystine lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLQALRAQLDLDGRVYFNHGGQGLLPESSLERLIWCYRHWRRCGPFSQQAERLAAEQVQRTREALATQLGVAGSTLSWAE
STSHSLNIALWGLDWRPGDGLLVSDCEHPGALAPACRVAERFGLQRQSVALSPAADPLAAVEAALQPNTRLVLLSHVLWN
SGRVLPVDQMTRLCRERGVLVLWDGAQGAGVLPLDYSQVDLYASTCHKWWMGPAGTGFLYVSERVRPRLQPTYVGWRSAE
RYWPDPVWYPDGRAFEVATIPVELLAALEQSLALHAQAGSADLRARAIRDLAGQLWERLKADPQVELLAEQPPEAGLVCW
RPKRALTFADLRSRVQWLEARGIFVRAIPQPLCLRASVHYFNTTGEIAALLEALERLD

Sequences:

>Translated_378_residues
MLQALRAQLDLDGRVYFNHGGQGLLPESSLERLIWCYRHWRRCGPFSQQAERLAAEQVQRTREALATQLGVAGSTLSWAE
STSHSLNIALWGLDWRPGDGLLVSDCEHPGALAPACRVAERFGLQRQSVALSPAADPLAAVEAALQPNTRLVLLSHVLWN
SGRVLPVDQMTRLCRERGVLVLWDGAQGAGVLPLDYSQVDLYASTCHKWWMGPAGTGFLYVSERVRPRLQPTYVGWRSAE
RYWPDPVWYPDGRAFEVATIPVELLAALEQSLALHAQAGSADLRARAIRDLAGQLWERLKADPQVELLAEQPPEAGLVCW
RPKRALTFADLRSRVQWLEARGIFVRAIPQPLCLRASVHYFNTTGEIAALLEALERLD
>Mature_378_residues
MLQALRAQLDLDGRVYFNHGGQGLLPESSLERLIWCYRHWRRCGPFSQQAERLAAEQVQRTREALATQLGVAGSTLSWAE
STSHSLNIALWGLDWRPGDGLLVSDCEHPGALAPACRVAERFGLQRQSVALSPAADPLAAVEAALQPNTRLVLLSHVLWN
SGRVLPVDQMTRLCRERGVLVLWDGAQGAGVLPLDYSQVDLYASTCHKWWMGPAGTGFLYVSERVRPRLQPTYVGWRSAE
RYWPDPVWYPDGRAFEVATIPVELLAALEQSLALHAQAGSADLRARAIRDLAGQLWERLKADPQVELLAEQPPEAGLVCW
RPKRALTFADLRSRVQWLEARGIFVRAIPQPLCLRASVHYFNTTGEIAALLEALERLD

Specific function: Fe-S cluster biosynthesis [C]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=213, Percent_Identity=30.0469483568075, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI48994898, Length=262, Percent_Identity=27.0992366412214, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1789175, Length=392, Percent_Identity=27.0408163265306, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787970, Length=349, Percent_Identity=24.9283667621776, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129463, Length=184, Percent_Identity=32.0652173913043, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 42132; Mature: 42132

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQALRAQLDLDGRVYFNHGGQGLLPESSLERLIWCYRHWRRCGPFSQQAERLAAEQVQR
CCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TREALATQLGVAGSTLSWAESTSHSLNIALWGLDWRPGDGLLVSDCEHPGALAPACRVAE
HHHHHHHHHCCCCCCCCHHCCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHH
RFGLQRQSVALSPAADPLAAVEAALQPNTRLVLLSHVLWNSGRVLPVDQMTRLCRERGVL
HHCCCHHCEECCCCCCHHHHHHHHHCCCCEEEEEEHHHHCCCCEEEHHHHHHHHHHCCEE
VLWDGAQGAGVLPLDYSQVDLYASTCHKWWMGPAGTGFLYVSERVRPRLQPTYVGWRSAE
EEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
RYWPDPVWYPDGRAFEVATIPVELLAALEQSLALHAQAGSADLRARAIRDLAGQLWERLK
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHC
ADPQVELLAEQPPEAGLVCWRPKRALTFADLRSRVQWLEARGIFVRAIPQPLCLRASVHY
CCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEE
FNTTGEIAALLEALERLD
ECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQALRAQLDLDGRVYFNHGGQGLLPESSLERLIWCYRHWRRCGPFSQQAERLAAEQVQR
CCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TREALATQLGVAGSTLSWAESTSHSLNIALWGLDWRPGDGLLVSDCEHPGALAPACRVAE
HHHHHHHHHCCCCCCCCHHCCCCCEEEEEEEECCCCCCCCCEEECCCCCCCCCHHHHHHH
RFGLQRQSVALSPAADPLAAVEAALQPNTRLVLLSHVLWNSGRVLPVDQMTRLCRERGVL
HHCCCHHCEECCCCCCHHHHHHHHHCCCCEEEEEEHHHHCCCCEEEHHHHHHHHHHCCEE
VLWDGAQGAGVLPLDYSQVDLYASTCHKWWMGPAGTGFLYVSERVRPRLQPTYVGWRSAE
EEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
RYWPDPVWYPDGRAFEVATIPVELLAALEQSLALHAQAGSADLRARAIRDLAGQLWERLK
CCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHC
ADPQVELLAEQPPEAGLVCWRPKRALTFADLRSRVQWLEARGIFVRAIPQPLCLRASVHY
CCCCEEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEEE
FNTTGEIAALLEALERLD
ECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]