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The map label for this gene is murB [H]

Identifier: 37523277

GI number: 37523277

Start: 3918764

End: 3919603

Strand: Reverse

Name: murB [H]

Synonym: gll3708

Alternate gene names: 37523277

Gene position: 3919603-3918764 (Counterclockwise)

Preceding gene: 37523278

Following gene: 37523276

Centisome position: 84.13

GC content: 56.67

Gene sequence:

>840_bases
ATGGTCGCCGTTACTGCCTTCGACACCAGCCAACTTTCGACGTTCCGAACCCACCACCACTTCGAGCGCTACGGTGAATT
CAAAAGCGCCGAAGAATTCGCCGAGTACTGCCGGTGGGCGGACGGACACAGCGCCCGGGTTTATATTCTGGGCAACGGCT
CCAATACCCTGTTTGCCCGCCCCTCGGTGCGCTCGCTGGTGCTCAAAAACAGCCTGCCCAGAACGATTCGATCGCTGGGC
GACGGTCGGGTGGAAGTGTCCTCGACCGTGCAGATCAACGAAGTGCTGAACTATTGCTATCAGCACGCCCTCGATTCGTT
TTACTACCTGGCCTCGGTGCCCGCTTCGATCGGTGGGGCGCTCGCGATGAACGCCGGCCGGGGCAAAACCCACCACTGCA
CGATCTACGATTTTGTCGAAAGCGTCACTTACGTTCACGAAGGTGCGGTGCAGACCCTCTCGAACGCTGAGATCCAACGG
GGTTACCGCAGGACGATGTTCACCGGTATCCAGCGCAGCTTGATCCTCAGTGCGGTTCTGCGCTTCGACGCGGCGCACTT
CGAGCACAATCCGCTCACCGAGAGGCGGCAGTGGGCCAAAGAACACCAGGATAATACCCTGCCCAACTGCGGCACGGTCT
TCAAGTACGCGAGCTACCCGATCATGAACCGCCTGCGCGGTCTGCGCATTGGTGATGCTTACTTTTCTTCGAAGACGAGC
AACTGGATATTGAACAAATCCAGCAGCAGCGCTCCGATTCTCACTTTGATCAAAGTTGCCAAAGTCCTGCATTATCTAAG
TTTCAAAAAGATCGACCTCGAAGTGATTGAAGTCGATTAG

Upstream 100 bases:

>100_bases
TCTGTTCGCGCGTGCCCTCGATTATGCGCGCCTGTTGGTGCCGCTCGGTGCGGGCAGCCGGGCGCCGTCTTAAGCGTCGT
TATTTTGGAGTGCCTTGCAT

Downstream 100 bases:

>100_bases
CGGTTGTTTTGCATTCTTTTCGAGGGATCACACAGCATGAAAATCGGGATTGTCACGTTCCACCACACTACCAACTACGG
CGCCACTCTGCAGACGTATG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFARPSVRSLVLKNSLPRTIRSLG
DGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGALAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQR
GYRRTMFTGIQRSLILSAVLRFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTS
NWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD

Sequences:

>Translated_279_residues
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFARPSVRSLVLKNSLPRTIRSLG
DGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGALAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQR
GYRRTMFTGIQRSLILSAVLRFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTS
NWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD
>Mature_279_residues
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFARPSVRSLVLKNSLPRTIRSLG
DGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGALAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQR
GYRRTMFTGIQRSLILSAVLRFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTS
NWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 31542; Mature: 31542

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFAR
CEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEC
PSVRSLVLKNSLPRTIRSLGDGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGA
CHHHHHHHHCCCHHHHHHCCCCCEEEECCEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
LAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQRGYRRTMFTGIQRSLILSAVL
EEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTS
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHCCCEECHHHHCCCCC
NWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD
CEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEC
>Mature Secondary Structure
MVAVTAFDTSQLSTFRTHHHFERYGEFKSAEEFAEYCRWADGHSARVYILGNGSNTLFAR
CEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEEEEC
PSVRSLVLKNSLPRTIRSLGDGRVEVSSTVQINEVLNYCYQHALDSFYYLASVPASIGGA
CHHHHHHHHCCCHHHHHHCCCCCEEEECCEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
LAMNAGRGKTHHCTIYDFVESVTYVHEGAVQTLSNAEIQRGYRRTMFTGIQRSLILSAVL
EEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFDAAHFEHNPLTERRQWAKEHQDNTLPNCGTVFKYASYPIMNRLRGLRIGDAYFSSKTS
HHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHCCCEECHHHHCCCCC
NWILNKSSSSAPILTLIKVAKVLHYLSFKKIDLEVIEVD
CEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]