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The map label for this gene is grxC [C]

Identifier: 37523252

GI number: 37523252

Start: 3890788

End: 3891051

Strand: Reverse

Name: grxC [C]

Synonym: gsl3683

Alternate gene names: 37523252

Gene position: 3891051-3890788 (Counterclockwise)

Preceding gene: 37523254

Following gene: 37523251

Centisome position: 83.52

GC content: 57.58

Gene sequence:

>264_bases
ATGAACCCCAAGGTTGAAATTTATACCTGGCAATTCTGTCCGTTCTGCATTCGTGCAAAGGCTCTGCTCAAGCAAAAAAG
TGTAGCCTTTAGCGAATACGCCATCGACGGCGACGAGGCTGCGCGCTCGGCGATGGCCGAGCGCGCCGACGGCAGGCGCA
GTGTGCCGCAGATATTTATCGACGGCAAGCACATCGGCGGTTGCGACGATCTATACGCCCTCGATCGCTCCGGCCAGCTC
GATCCGCTGCTTGTCGCTTCATGA

Upstream 100 bases:

>100_bases
GGTTGCTGCTCTTCAGTGTCCTACGGCTTGCAGCGAGGCAGCCCCATTTCCGACGGAAGTTACAATGGTGGCAAGGGCGA
ACGCCCATTGGAGGCCTTTG

Downstream 100 bases:

>100_bases
AGATTCTTTTTATCGTCGATCCGCTCGAGACCCTTAAACCCGGTCACGACACTTCGGTTGCCCTGATGCAGGCCGCCGCG
CGCCGCGGCCACAGCGTTTG

Product: glutaredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 87

Protein sequence:

>87_residues
MNPKVEIYTWQFCPFCIRAKALLKQKSVAFSEYAIDGDEAARSAMAERADGRRSVPQIFIDGKHIGGCDDLYALDRSGQL
DPLLVAS

Sequences:

>Translated_87_residues
MNPKVEIYTWQFCPFCIRAKALLKQKSVAFSEYAIDGDEAARSAMAERADGRRSVPQIFIDGKHIGGCDDLYALDRSGQL
DPLLVAS
>Mature_87_residues
MNPKVEIYTWQFCPFCIRAKALLKQKSVAFSEYAIDGDEAARSAMAERADGRRSVPQIFIDGKHIGGCDDLYALDRSGQL
DPLLVAS

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaredoxin family [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=81, Percent_Identity=64.1975308641975, Blast_Score=107, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9637; Mature: 9637

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKVEIYTWQFCPFCIRAKALLKQKSVAFSEYAIDGDEAARSAMAERADGRRSVPQIFI
CCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEE
DGKHIGGCDDLYALDRSGQLDPLLVAS
CCCCCCCCCCCEEECCCCCCCEEEECC
>Mature Secondary Structure
MNPKVEIYTWQFCPFCIRAKALLKQKSVAFSEYAIDGDEAARSAMAERADGRRSVPQIFI
CCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEE
DGKHIGGCDDLYALDRSGQLDPLLVAS
CCCCCCCCCCCEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]