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The map label for this gene is ileS

Identifier: 37523220

GI number: 37523220

Start: 3850620

End: 3853571

Strand: Reverse

Name: ileS

Synonym: gvip495

Alternate gene names: 37523220

Gene position: 3853571-3850620 (Counterclockwise)

Preceding gene: 37523224

Following gene: 37523219

Centisome position: 82.71

GC content: 63.89

Gene sequence:

>2952_bases
GTGACCCAGACCCCCGTCGACTACAAGCAGACCGTCCGCACGCCCAAGACGGATTTTCCGATGCGGGCGAACGCCTCAAC
CCGCGAGGTCGAGATTCAGCGGTTCTGGGAAGAGCAGGGCATCTACGGACGTCTTGCCCAGGAAAACCCCGGCGAAATTT
TTATCCTGCACGACGGGCCGCCCTACGCCAACGGCGAGCTGCACGTCGGCCACGCCCTCAACAAGATCCTCAAGGACATC
ATCAACCGCTACCAGCTGTTGCAGGGGCGGCGGGTGCGCTACGTGCCCGGCTGGGACTGCCACGGGCTGCCGATTGAACT
CAAAGTGCTGCAGGATCTCTCCCAGGCGGAGCGCTCGCAATTGACGCCCCTCGATGTGCGCACGCGGGCGCGCGATTTCG
CCCAGCGCACCGTGCAGTCGCAGTGCGCGAGCTACAAGCGCTTCGGCGTCTGGGGCGATTGGGATCACCCGTACCTCACC
TTGCAGCCGGAGTACGAGGCGGCTCAGCTCGGGGTCTTCGGCAAGATGGCCCTCAAAGGCTATATCTACCGGGGCCTCAA
ACCCGTCCACTGGAGCCCCAGTTCACAGACTGCTCTGGCAGAAGCAGAACTGGAGTACCCGACCAAGGACGACGGCAGCC
CCGCCCACACCTCCCGCTCGGTCTACGTCAAGTTCCCGCTTATCTCCATCGCGGCACCCGAGACCGCCACGGTGATGGCC
GCCGAACTGCTGCCGCGCCTGAGCGCTTTTCACGACCGCGAAGAAGAACTGATCGATGCGCTGTTGGGTGAGCGCGACGA
CCTTCCCGAGATCGCCGTAGCCATCTGGACCACAACTCCCTGGACGCTGCCGGGCAACCTGGCGGTGGCGCTCAACGGCG
AACTCGACTACGCACTGGTGGCAAGCGACGAGCACGGCCTGCTCATCGTCGCGGCTGAACTGGTGGAGCGGCTGGCAGGG
ACGCTCGCCACCCGCTTTGAGACGATTGCCACCTTCAGAGGCCGCGAACTGGAGGGCAGCCTCCTGGCTCACCCACTCTT
CCGCCGCACCAGCCCAATCGTCCTGGGCGATCACGTCACCACCGAATCGGGCACAGGGGCGGTGCACACCGCCCCCGGCC
ACGGCAGTGAGGACTTTGAGCTGGCCCAGCGCTACAACCTCGGGGTGCTCTCGCCGGTGGACGATTACGGCCGCTTCACC
CGCGAGGCGGATAGCGACCGCCGCGAGAACCTGCCGGTCTTTGCCGGCAAGGCGGTGCTCAGCGACGGCAACCAGGCGGT
CATCGAAGCGCTCAGCGCGGCGGGAGCGCTGCTCAAAGAAGAAGCCTACGTCCACAAATATCCCTACGACTGGCGCACCA
AAAAACCGACCATCTTTCGGGCCACCACCCAGTGGTTCGCCTCGGTCTCCGATTTTCGCCCCCAGGCACTGAGCGCCATT
GCCCAGACCGAATGGATCCCCGCCAGCGGCGAGAACCGGATCACCGCCATGGTGGCCGGGCGCAACGACTGGTGCATCTC
CCGCCAGCGCGCCTGGGGACTGCCGATTCCGGCCTTCTACTGCGAAAACTGCGCCAACGTGCTGCTTACCCAGGAGTCGG
TCGAAGCGGTGCAGGCGGCCGTGCGCGTCCACGGCTCCGACATCTGGTGGCAAAAAGAAGCAAGCGAGCTGCTTCCCCCG
GGGATCGCCTGCGCCCACTGCGGCGGCACCGCCTTTCGCAAAGAAAAAGACATCATGGACGTCTGGTTCGACTCGGGTTC
TTCGTGGGCCGGGGTGCTCGGCCGGCGGCCCGAGTTGCACTACCCGGCCGATGTCTACCTCGAAGGATCCGATCAGCACC
GCGGCTGGTTCCAGTCGAGCCTACTCACCTGTGTGGCCACCGAGGGCACCGCCCCTTACAAAACCGTGATCACCCACGGC
TTCACCCTCGACGAGCACGGCCGCAAGATGTCCAAGTCTCTCGGCAACGTCGTGGACCCGAAACTGGTTATCGACGGCGG
GGCCAATCAGAAGCAGCACCCCGCCTACGGGGCGGACGTGCTGCGCCTCTGGGTTGCCTCGGTCGATTACACCAGCGATC
AGCTAGTCGGCCCCAGCGTGCTTGCCCAGATAGCCGAAGTGTATCGCAAGATCCGCAACACGGCGCGCTACCTGCTGGGT
AGCCTCAACGACTTCGTACCGGAGCGCGACCTGGTGGCCTTCGATTCGCTGGGCGAAGTCGATCAATACCTCCTGCACCG
CCTGAGTGTGGTGCATCTCGAAGTCACCCAGGCTTTTGAAAGTTACCAGTTCTCGCGCTTCTTCCAGACCATCCAGAACT
TCTGCGTGGCGGATCTGTCGAATTTTTATCTGGATATTTCCAAAGACCGCCTCTACATCAGTGCCGAAGTGTCCCTGCGC
CGCCGCAGCTGCCAGACGGTGCTCTACCGTGTGCTCGAAAGCCTCACCCGGCTGATTGCCCCGGTGCTGCCGCACCTGGC
GGAGGATATCTGGCAGCATCTGCCCTACCCCAGAAGCGACGCTTCGGTATTTGAGGCAGGTTGGCCGGTCGATCACTCCC
AGTGGTTCCAACCGCTCACGGTCGATCGTTGGCCAGGGCTGATTGTCCTGCGCGACCGGGTGAACATCGCCCTCGAAGCC
GCCCGCAACGCCAAACGCATCGGCTCCTCGCTGGAAGCCAAAATTCGACTGCACGTCGAAGACCCGGCCCTGACGGACGA
ACTGGCCCGCCAAAAAGACGAGTTGCGCTATTTGTTCATCGTCTCGCAGGTGGAACTGCTGGACGAACTCCCGGCCGAGG
TGTCCGTCGAGGAAGGGGCGGCGGTAATTGTACTCGATGCGGACGGTCAAAAGTGCGAGCGCTGCTGGAACTACTCGGTC
CATGTCGGCGAAGATGCCGAGCACCCGACGCTGTGCGAGCGGTGCGTCTCAGCTCTGGCCGGGGCGTTCTAG

Upstream 100 bases:

>100_bases
TCTTGCACAAAGGCACATCTCGCAATCGGCCCCGCTGTCGGCAGGGGCTGCCCTCCCCTAAACTGAAGAAAAGATTGCGC
TTTTGTTAGGAAACCACCCC

Downstream 100 bases:

>100_bases
AATGTCCAACGACGCCGGAGACCGGGTCTTTGCAGTCCTGGTCAACTGGTGTAACGACGGCGACACGCTCCGGGCGGTCG
AGTCGCTACTGGCGCAGAGC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 983; Mature: 982

Protein sequence:

>983_residues
MTQTPVDYKQTVRTPKTDFPMRANASTREVEIQRFWEEQGIYGRLAQENPGEIFILHDGPPYANGELHVGHALNKILKDI
INRYQLLQGRRVRYVPGWDCHGLPIELKVLQDLSQAERSQLTPLDVRTRARDFAQRTVQSQCASYKRFGVWGDWDHPYLT
LQPEYEAAQLGVFGKMALKGYIYRGLKPVHWSPSSQTALAEAELEYPTKDDGSPAHTSRSVYVKFPLISIAAPETATVMA
AELLPRLSAFHDREEELIDALLGERDDLPEIAVAIWTTTPWTLPGNLAVALNGELDYALVASDEHGLLIVAAELVERLAG
TLATRFETIATFRGRELEGSLLAHPLFRRTSPIVLGDHVTTESGTGAVHTAPGHGSEDFELAQRYNLGVLSPVDDYGRFT
READSDRRENLPVFAGKAVLSDGNQAVIEALSAAGALLKEEAYVHKYPYDWRTKKPTIFRATTQWFASVSDFRPQALSAI
AQTEWIPASGENRITAMVAGRNDWCISRQRAWGLPIPAFYCENCANVLLTQESVEAVQAAVRVHGSDIWWQKEASELLPP
GIACAHCGGTAFRKEKDIMDVWFDSGSSWAGVLGRRPELHYPADVYLEGSDQHRGWFQSSLLTCVATEGTAPYKTVITHG
FTLDEHGRKMSKSLGNVVDPKLVIDGGANQKQHPAYGADVLRLWVASVDYTSDQLVGPSVLAQIAEVYRKIRNTARYLLG
SLNDFVPERDLVAFDSLGEVDQYLLHRLSVVHLEVTQAFESYQFSRFFQTIQNFCVADLSNFYLDISKDRLYISAEVSLR
RRSCQTVLYRVLESLTRLIAPVLPHLAEDIWQHLPYPRSDASVFEAGWPVDHSQWFQPLTVDRWPGLIVLRDRVNIALEA
ARNAKRIGSSLEAKIRLHVEDPALTDELARQKDELRYLFIVSQVELLDELPAEVSVEEGAAVIVLDADGQKCERCWNYSV
HVGEDAEHPTLCERCVSALAGAF

Sequences:

>Translated_983_residues
MTQTPVDYKQTVRTPKTDFPMRANASTREVEIQRFWEEQGIYGRLAQENPGEIFILHDGPPYANGELHVGHALNKILKDI
INRYQLLQGRRVRYVPGWDCHGLPIELKVLQDLSQAERSQLTPLDVRTRARDFAQRTVQSQCASYKRFGVWGDWDHPYLT
LQPEYEAAQLGVFGKMALKGYIYRGLKPVHWSPSSQTALAEAELEYPTKDDGSPAHTSRSVYVKFPLISIAAPETATVMA
AELLPRLSAFHDREEELIDALLGERDDLPEIAVAIWTTTPWTLPGNLAVALNGELDYALVASDEHGLLIVAAELVERLAG
TLATRFETIATFRGRELEGSLLAHPLFRRTSPIVLGDHVTTESGTGAVHTAPGHGSEDFELAQRYNLGVLSPVDDYGRFT
READSDRRENLPVFAGKAVLSDGNQAVIEALSAAGALLKEEAYVHKYPYDWRTKKPTIFRATTQWFASVSDFRPQALSAI
AQTEWIPASGENRITAMVAGRNDWCISRQRAWGLPIPAFYCENCANVLLTQESVEAVQAAVRVHGSDIWWQKEASELLPP
GIACAHCGGTAFRKEKDIMDVWFDSGSSWAGVLGRRPELHYPADVYLEGSDQHRGWFQSSLLTCVATEGTAPYKTVITHG
FTLDEHGRKMSKSLGNVVDPKLVIDGGANQKQHPAYGADVLRLWVASVDYTSDQLVGPSVLAQIAEVYRKIRNTARYLLG
SLNDFVPERDLVAFDSLGEVDQYLLHRLSVVHLEVTQAFESYQFSRFFQTIQNFCVADLSNFYLDISKDRLYISAEVSLR
RRSCQTVLYRVLESLTRLIAPVLPHLAEDIWQHLPYPRSDASVFEAGWPVDHSQWFQPLTVDRWPGLIVLRDRVNIALEA
ARNAKRIGSSLEAKIRLHVEDPALTDELARQKDELRYLFIVSQVELLDELPAEVSVEEGAAVIVLDADGQKCERCWNYSV
HVGEDAEHPTLCERCVSALAGAF
>Mature_982_residues
TQTPVDYKQTVRTPKTDFPMRANASTREVEIQRFWEEQGIYGRLAQENPGEIFILHDGPPYANGELHVGHALNKILKDII
NRYQLLQGRRVRYVPGWDCHGLPIELKVLQDLSQAERSQLTPLDVRTRARDFAQRTVQSQCASYKRFGVWGDWDHPYLTL
QPEYEAAQLGVFGKMALKGYIYRGLKPVHWSPSSQTALAEAELEYPTKDDGSPAHTSRSVYVKFPLISIAAPETATVMAA
ELLPRLSAFHDREEELIDALLGERDDLPEIAVAIWTTTPWTLPGNLAVALNGELDYALVASDEHGLLIVAAELVERLAGT
LATRFETIATFRGRELEGSLLAHPLFRRTSPIVLGDHVTTESGTGAVHTAPGHGSEDFELAQRYNLGVLSPVDDYGRFTR
EADSDRRENLPVFAGKAVLSDGNQAVIEALSAAGALLKEEAYVHKYPYDWRTKKPTIFRATTQWFASVSDFRPQALSAIA
QTEWIPASGENRITAMVAGRNDWCISRQRAWGLPIPAFYCENCANVLLTQESVEAVQAAVRVHGSDIWWQKEASELLPPG
IACAHCGGTAFRKEKDIMDVWFDSGSSWAGVLGRRPELHYPADVYLEGSDQHRGWFQSSLLTCVATEGTAPYKTVITHGF
TLDEHGRKMSKSLGNVVDPKLVIDGGANQKQHPAYGADVLRLWVASVDYTSDQLVGPSVLAQIAEVYRKIRNTARYLLGS
LNDFVPERDLVAFDSLGEVDQYLLHRLSVVHLEVTQAFESYQFSRFFQTIQNFCVADLSNFYLDISKDRLYISAEVSLRR
RSCQTVLYRVLESLTRLIAPVLPHLAEDIWQHLPYPRSDASVFEAGWPVDHSQWFQPLTVDRWPGLIVLRDRVNIALEAA
RNAKRIGSSLEAKIRLHVEDPALTDELARQKDELRYLFIVSQVELLDELPAEVSVEEGAAVIVLDADGQKCERCWNYSVH
VGEDAEHPTLCERCVSALAGAF

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI46852147, Length=1002, Percent_Identity=40.9181636726547, Blast_Score=761, Evalue=0.0,
Organism=Homo sapiens, GI94721239, Length=849, Percent_Identity=28.7396937573616, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI94721241, Length=849, Percent_Identity=28.7396937573616, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI268370293, Length=863, Percent_Identity=24.6813441483198, Blast_Score=194, Evalue=5e-49,
Organism=Homo sapiens, GI268370297, Length=863, Percent_Identity=24.6813441483198, Blast_Score=193, Evalue=8e-49,
Organism=Homo sapiens, GI268370295, Length=816, Percent_Identity=24.5098039215686, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI5454158, Length=595, Percent_Identity=25.3781512605042, Blast_Score=153, Evalue=7e-37,
Organism=Escherichia coli, GI2367096, Length=993, Percent_Identity=40.785498489426, Blast_Score=714, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=959, Percent_Identity=23.8790406673618, Blast_Score=181, Evalue=3e-46,
Organism=Escherichia coli, GI1786861, Length=904, Percent_Identity=22.0132743362832, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71980946, Length=1007, Percent_Identity=33.862959285005, Blast_Score=501, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17541896, Length=859, Percent_Identity=26.8917345750873, Blast_Score=285, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI72001587, Length=845, Percent_Identity=24.2603550295858, Blast_Score=165, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17510661, Length=588, Percent_Identity=26.8707482993197, Blast_Score=165, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325217, Length=1028, Percent_Identity=36.4785992217899, Blast_Score=618, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319395, Length=941, Percent_Identity=25.9298618490967, Blast_Score=291, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6321531, Length=870, Percent_Identity=25.4022988505747, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323414, Length=419, Percent_Identity=24.8210023866348, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281366294, Length=847, Percent_Identity=38.1345926800472, Blast_Score=527, Evalue=1e-149,
Organism=Drosophila melanogaster, GI28574730, Length=1020, Percent_Identity=26.2745098039216, Blast_Score=292, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24668547, Length=1020, Percent_Identity=26.2745098039216, Blast_Score=292, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24668543, Length=1020, Percent_Identity=26.2745098039216, Blast_Score=292, Evalue=8e-79,
Organism=Drosophila melanogaster, GI21355675, Length=881, Percent_Identity=21.9069239500568, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17864482, Length=681, Percent_Identity=24.6696035242291, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24653289, Length=681, Percent_Identity=24.6696035242291, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355409, Length=370, Percent_Identity=23.5135135135135, Blast_Score=72, Evalue=3e-12,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_GLOVI (Q7NF75)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926597.1
- ProteinModelPortal:   Q7NF75
- SMR:   Q7NF75
- GeneID:   2602055
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3651
- HOGENOM:   HBG577712
- OMA:   KQVLTHG
- ProtClustDB:   PRK05743
- BioCyc:   GVIO251221:GLL3651-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02002
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- InterPro:   IPR010663
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF06827 zf-FPG_IleRS; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 110015; Mature: 109884

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 608-608 BINDING 652-652

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTPVDYKQTVRTPKTDFPMRANASTREVEIQRFWEEQGIYGRLAQENPGEIFILHDGP
CCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCC
PYANGELHVGHALNKILKDIINRYQLLQGRRVRYVPGWDCHGLPIELKVLQDLSQAERSQ
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
LTPLDVRTRARDFAQRTVQSQCASYKRFGVWGDWDHPYLTLQPEYEAAQLGVFGKMALKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHCHHHHHHHHH
YIYRGLKPVHWSPSSQTALAEAELEYPTKDDGSPAHTSRSVYVKFPLISIAAPETATVMA
HHHHCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHH
AELLPRLSAFHDREEELIDALLGERDDLPEIAVAIWTTTPWTLPGNLAVALNGELDYALV
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEE
ASDEHGLLIVAAELVERLAGTLATRFETIATFRGRELEGSLLAHPLFRRTSPIVLGDHVT
ECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCEE
TESGTGAVHTAPGHGSEDFELAQRYNLGVLSPVDDYGRFTREADSDRRENLPVFAGKAVL
CCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHCCCCEEECCHHH
SDGNQAVIEALSAAGALLKEEAYVHKYPYDWRTKKPTIFRATTQWFASVSDFRPQALSAI
CCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHH
AQTEWIPASGENRITAMVAGRNDWCISRQRAWGLPIPAFYCENCANVLLTQESVEAVQAA
HHHCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHEECHHHHHHHHHH
VRVHGSDIWWQKEASELLPPGIACAHCGGTAFRKEKDIMDVWFDSGSSWAGVLGRRPELH
HHHCCCCCEECCCHHHHCCCCCEEECCCCHHHHCCCCCHHHEECCCCCHHHHHCCCCCCC
YPADVYLEGSDQHRGWFQSSLLTCVATEGTAPYKTVITHGFTLDEHGRKMSKSLGNVVDP
CCCEEEEECCCCCCHHHHHHHHEEEECCCCCCHHHHHHCCCEECHHHHHHHHHHCCCCCC
KLVIDGGANQKQHPAYGADVLRLWVASVDYTSDQLVGPSVLAQIAEVYRKIRNTARYLLG
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLNDFVPERDLVAFDSLGEVDQYLLHRLSVVHLEVTQAFESYQFSRFFQTIQNFCVADLS
HHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFYLDISKDRLYISAEVSLRRRSCQTVLYRVLESLTRLIAPVLPHLAEDIWQHLPYPRSD
HHEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASVFEAGWPVDHSQWFQPLTVDRWPGLIVLRDRVNIALEAARNAKRIGSSLEAKIRLHVE
CCCEECCCCCCHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEC
DPALTDELARQKDELRYLFIVSQVELLDELPAEVSVEEGAAVIVLDADGQKCERCWNYSV
CCCHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHCCCCE
HVGEDAEHPTLCERCVSALAGAF
EECCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TQTPVDYKQTVRTPKTDFPMRANASTREVEIQRFWEEQGIYGRLAQENPGEIFILHDGP
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCC
PYANGELHVGHALNKILKDIINRYQLLQGRRVRYVPGWDCHGLPIELKVLQDLSQAERSQ
CCCCCCEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
LTPLDVRTRARDFAQRTVQSQCASYKRFGVWGDWDHPYLTLQPEYEAAQLGVFGKMALKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHCHHHHHHHHH
YIYRGLKPVHWSPSSQTALAEAELEYPTKDDGSPAHTSRSVYVKFPLISIAAPETATVMA
HHHHCCCCEECCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHH
AELLPRLSAFHDREEELIDALLGERDDLPEIAVAIWTTTPWTLPGNLAVALNGELDYALV
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEE
ASDEHGLLIVAAELVERLAGTLATRFETIATFRGRELEGSLLAHPLFRRTSPIVLGDHVT
ECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEECCEE
TESGTGAVHTAPGHGSEDFELAQRYNLGVLSPVDDYGRFTREADSDRRENLPVFAGKAVL
CCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHCCCCEEECCHHH
SDGNQAVIEALSAAGALLKEEAYVHKYPYDWRTKKPTIFRATTQWFASVSDFRPQALSAI
CCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCHHHHHHH
AQTEWIPASGENRITAMVAGRNDWCISRQRAWGLPIPAFYCENCANVLLTQESVEAVQAA
HHHCCCCCCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHEECHHHHHHHHHH
VRVHGSDIWWQKEASELLPPGIACAHCGGTAFRKEKDIMDVWFDSGSSWAGVLGRRPELH
HHHCCCCCEECCCHHHHCCCCCEEECCCCHHHHCCCCCHHHEECCCCCHHHHHCCCCCCC
YPADVYLEGSDQHRGWFQSSLLTCVATEGTAPYKTVITHGFTLDEHGRKMSKSLGNVVDP
CCCEEEEECCCCCCHHHHHHHHEEEECCCCCCHHHHHHCCCEECHHHHHHHHHHCCCCCC
KLVIDGGANQKQHPAYGADVLRLWVASVDYTSDQLVGPSVLAQIAEVYRKIRNTARYLLG
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLNDFVPERDLVAFDSLGEVDQYLLHRLSVVHLEVTQAFESYQFSRFFQTIQNFCVADLS
HHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFYLDISKDRLYISAEVSLRRRSCQTVLYRVLESLTRLIAPVLPHLAEDIWQHLPYPRSD
HHEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASVFEAGWPVDHSQWFQPLTVDRWPGLIVLRDRVNIALEAARNAKRIGSSLEAKIRLHVE
CCCEECCCCCCHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEEC
DPALTDELARQKDELRYLFIVSQVELLDELPAEVSVEEGAAVIVLDADGQKCERCWNYSV
CCCHHHHHHHHHHHEEEEEEHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHCCCCE
HVGEDAEHPTLCERCVSALAGAF
EECCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292