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The map label for this gene is glcK [H]

Identifier: 37523199

GI number: 37523199

Start: 3828107

End: 3828991

Strand: Reverse

Name: glcK [H]

Synonym: gll3630

Alternate gene names: 37523199

Gene position: 3828991-3828107 (Counterclockwise)

Preceding gene: 37523200

Following gene: 37523198

Centisome position: 82.18

GC content: 67.46

Gene sequence:

>885_bases
ATGGGCTCGGTCGTCGCCATCGATCTCGGGGGTACCGCCATCAAAGCCGGCCGTTACGACGGACAGGGCCGGGAACTGGC
GAGCGCCACGATCGCAACCCCCCGGCCGAGCACCCCCGAGGCGGTGCTCGCAGCCCTGAGCGCTCTGGTGGCGGTGCTCG
ATCCTGGAAGGGAAGCTGTCGCTCTCGGCGTGGGCGTACCGGGGTTGGTCGATGTCGGCGGCCGGCTGGTGTACACCTGC
ATCAACCTCGACGGCTGGCGCGACGTGCCGATGGCCCGCCTGCTGGAGGAGAAGACCGGCCTGTCGACGGTGCTGGGCAA
CGACGCCAACCTGGCCGGTTTGGGAGAAAACTGGCTCGGCAGCGCCAGCCGCTTCGGCCACGTCATCTTCATCACCCTGG
GTACGGGCGTGGGGGGCAGCCTTATCCACAATCGCCGACTATTCACCGGTGCCCACGGCCTGGGGGGCGAGTTGGGCCAT
ATGGTCTTCGATCCGCGCGGTCCGCGCTGCAACTGCGGCAGCAGCGGCTGCCTGGAACAATTTATCGCAGCCCCAGCCAT
CGCCCGCCGCTTCGGGCTTGACCCCGCGGTGCTCGGCGAGCGGGCGGCAGCAGGTGACCCCCAGGCCCTCGAATGTTGGC
GGCAGGTGGGGCGCGACCTGGGCTACGCCCTGGTCGGTCTGGTGAACCTGCTCGACCCGGAGGCGGTGGTGATTGGCGGC
GGGGTGAGCAAAAGCTGCCCCTACTTCCTGAGCGAGGCTGAGGCTGAAATTGACCGCCGCTCGATCATCAAGCGGCCCTG
GTTGCAACTTTTGCAGGCGGAGCTCGGCAACGAAGCAGGTTGCATCGGCGCGGCGCGCCTGGCATTTCTAACGTTTACTT
CTTGA

Upstream 100 bases:

>100_bases
TCCCCCGCCGCTGCAGAGCGGCCCTACCGGACAGGAGAGCGCCCCGAGCGCCCGCGCATCGAGCGACCCCGCCGCTTCAA
CCCTCAACCCGGCTCCTAGC

Downstream 100 bases:

>100_bases
GTTTTGTCGTTACTTAATTAGAGCTCTGCTTCGGCCTGGGTTGCTGTGACGACGTTATGTTTATTAACTTCAGAATGGTT
TATAGACGTGATGCAAGTGT

Product: sugar kinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MGSVVAIDLGGTAIKAGRYDGQGRELASATIATPRPSTPEAVLAALSALVAVLDPGREAVALGVGVPGLVDVGGRLVYTC
INLDGWRDVPMARLLEEKTGLSTVLGNDANLAGLGENWLGSASRFGHVIFITLGTGVGGSLIHNRRLFTGAHGLGGELGH
MVFDPRGPRCNCGSSGCLEQFIAAPAIARRFGLDPAVLGERAAAGDPQALECWRQVGRDLGYALVGLVNLLDPEAVVIGG
GVSKSCPYFLSEAEAEIDRRSIIKRPWLQLLQAELGNEAGCIGAARLAFLTFTS

Sequences:

>Translated_294_residues
MGSVVAIDLGGTAIKAGRYDGQGRELASATIATPRPSTPEAVLAALSALVAVLDPGREAVALGVGVPGLVDVGGRLVYTC
INLDGWRDVPMARLLEEKTGLSTVLGNDANLAGLGENWLGSASRFGHVIFITLGTGVGGSLIHNRRLFTGAHGLGGELGH
MVFDPRGPRCNCGSSGCLEQFIAAPAIARRFGLDPAVLGERAAAGDPQALECWRQVGRDLGYALVGLVNLLDPEAVVIGG
GVSKSCPYFLSEAEAEIDRRSIIKRPWLQLLQAELGNEAGCIGAARLAFLTFTS
>Mature_293_residues
GSVVAIDLGGTAIKAGRYDGQGRELASATIATPRPSTPEAVLAALSALVAVLDPGREAVALGVGVPGLVDVGGRLVYTCI
NLDGWRDVPMARLLEEKTGLSTVLGNDANLAGLGENWLGSASRFGHVIFITLGTGVGGSLIHNRRLFTGAHGLGGELGHM
VFDPRGPRCNCGSSGCLEQFIAAPAIARRFGLDPAVLGERAAAGDPQALECWRQVGRDLGYALVGLVNLLDPEAVVIGGG
VSKSCPYFLSEAEAEIDRRSIIKRPWLQLLQAELGNEAGCIGAARLAFLTFTS

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=278, Percent_Identity=25.5395683453237, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI298566325, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4885285, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI190014632, Length=266, Percent_Identity=26.6917293233083, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786891, Length=306, Percent_Identity=29.0849673202614, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082230, Length=245, Percent_Identity=35.1020408163265, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787363, Length=306, Percent_Identity=31.0457516339869, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081733, Length=259, Percent_Identity=27.4131274131274, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787878, Length=201, Percent_Identity=25.3731343283582, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790522, Length=303, Percent_Identity=26.4026402640264, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082127, Length=176, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 30496; Mature: 30365

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSVVAIDLGGTAIKAGRYDGQGRELASATIATPRPSTPEAVLAALSALVAVLDPGREAV
CCCEEEEECCCCEEECCCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ALGVGVPGLVDVGGRLVYTCINLDGWRDVPMARLLEEKTGLSTVLGNDANLAGLGENWLG
EEECCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHCC
SASRFGHVIFITLGTGVGGSLIHNRRLFTGAHGLGGELGHMVFDPRGPRCNCGSSGCLEQ
CHHCCCEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHH
FIAAPAIARRFGLDPAVLGERAAAGDPQALECWRQVGRDLGYALVGLVNLLDPEAVVIGG
HHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GVSKSCPYFLSEAEAEIDRRSIIKRPWLQLLQAELGNEAGCIGAARLAFLTFTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECC
>Mature Secondary Structure 
GSVVAIDLGGTAIKAGRYDGQGRELASATIATPRPSTPEAVLAALSALVAVLDPGREAV
CCEEEEECCCCEEECCCCCCCCCHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEE
ALGVGVPGLVDVGGRLVYTCINLDGWRDVPMARLLEEKTGLSTVLGNDANLAGLGENWLG
EEECCCCHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCHHCC
SASRFGHVIFITLGTGVGGSLIHNRRLFTGAHGLGGELGHMVFDPRGPRCNCGSSGCLEQ
CHHCCCEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHH
FIAAPAIARRFGLDPAVLGERAAAGDPQALECWRQVGRDLGYALVGLVNLLDPEAVVIGG
HHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GVSKSCPYFLSEAEAEIDRRSIIKRPWLQLLQAELGNEAGCIGAARLAFLTFTS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]