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The map label for this gene is algU [H]

Identifier: 37523153

GI number: 37523153

Start: 3776188

End: 3776751

Strand: Direct

Name: algU [H]

Synonym: glr3584

Alternate gene names: 37523153

Gene position: 3776188-3776751 (Clockwise)

Preceding gene: 37523152

Following gene: 37523154

Centisome position: 81.05

GC content: 64.01

Gene sequence:

>564_bases
ATGCGTGTGGGCGTTGCTGTGACCCAGGTGAGCGACGAGCAACTGGTCTGGCGGGCGAGTCGCTCCGACGGCCAGGCGTT
TCGGGAGCTTTACCGGCGCTATGTCTCGAAGGTGCGCGGCCTGCTCTATCAGATGATGAGCGACATCGAAAGCCTGGATG
ATCTCACCCAGGAAGTTTTCGTCAAGGTCTTCAAGGCGCTGCCGGGTTTTCGGGGGGATGCCCAGTTTTCGACGTGGTTG
TTCCGCATCGCCGTCAACTGCTGCCAGGACGCCCGCCGCCGCCGCGCCCGCCGGCCGATGGCCGTGCCCATAGACAATCT
GCCGCTCGCCGCGCGCGGCGAGGATCCGCTCGGGCGCCTCGACCGCGAGCAGCTTGTGTCGCAGGCGCTCGCCACGCTCA
AGGAAGAGCACCGCGATGTGGTGATTTTGCACGATCTGCACGATCGCCCGCAGGATGAAATTGCCAAACTGTTGAACGTG
CCCGTCGGCACGGTCAAATCGCGGTTGTTCTACGCGCGCCGCCAGTTGCGCGAATGGTTCTACGCCCGGGGGATCGAGCT
ATGA

Upstream 100 bases:

>100_bases
ATCGAAGGCCACAACTGTCAGGGAAGCAACTGTTAGCGTCGCTGTGTGAACCTGTCTGTTCACCCGGGCGTCAATGGGTG
TACAAAGCGAGAGAGGTTCG

Downstream 100 bases:

>100_bases
GTGACCCGTTACAAGAATTTTTGCGCCGCAACGCTCCCGAGCCCCCCGCCCCGGCCAGGGATCTCGAGGAGCGCATTCTC
GAAGCCACCCTGGCACCCAC

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-30 [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MRVGVAVTQVSDEQLVWRASRSDGQAFRELYRRYVSKVRGLLYQMMSDIESLDDLTQEVFVKVFKALPGFRGDAQFSTWL
FRIAVNCCQDARRRRARRPMAVPIDNLPLAARGEDPLGRLDREQLVSQALATLKEEHRDVVILHDLHDRPQDEIAKLLNV
PVGTVKSRLFYARRQLREWFYARGIEL

Sequences:

>Translated_187_residues
MRVGVAVTQVSDEQLVWRASRSDGQAFRELYRRYVSKVRGLLYQMMSDIESLDDLTQEVFVKVFKALPGFRGDAQFSTWL
FRIAVNCCQDARRRRARRPMAVPIDNLPLAARGEDPLGRLDREQLVSQALATLKEEHRDVVILHDLHDRPQDEIAKLLNV
PVGTVKSRLFYARRQLREWFYARGIEL
>Mature_187_residues
MRVGVAVTQVSDEQLVWRASRSDGQAFRELYRRYVSKVRGLLYQMMSDIESLDDLTQEVFVKVFKALPGFRGDAQFSTWL
FRIAVNCCQDARRRRARRPMAVPIDNLPLAARGEDPLGRLDREQLVSQALATLKEEHRDVVILHDLHDRPQDEIAKLLNV
PVGTVKSRLFYARRQLREWFYARGIEL

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=179, Percent_Identity=33.5195530726257, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21742; Mature: 21742

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVAVTQVSDEQLVWRASRSDGQAFRELYRRYVSKVRGLLYQMMSDIESLDDLTQEVF
CCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVFKALPGFRGDAQFSTWLFRIAVNCCQDARRRRARRPMAVPIDNLPLAARGEDPLGRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
DREQLVSQALATLKEEHRDVVILHDLHDRPQDEIAKLLNVPVGTVKSRLFYARRQLREWF
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YARGIEL
HHHCCCC
>Mature Secondary Structure
MRVGVAVTQVSDEQLVWRASRSDGQAFRELYRRYVSKVRGLLYQMMSDIESLDDLTQEVF
CCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVFKALPGFRGDAQFSTWLFRIAVNCCQDARRRRARRPMAVPIDNLPLAARGEDPLGRL
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHC
DREQLVSQALATLKEEHRDVVILHDLHDRPQDEIAKLLNVPVGTVKSRLFYARRQLREWF
CHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
YARGIEL
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8432708; 8378309; 7961421; 10984043; 7737518 [H]