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The map label for this gene is rpe [H]

Identifier: 37523117

GI number: 37523117

Start: 3745020

End: 3745721

Strand: Reverse

Name: rpe [H]

Synonym: gll3548

Alternate gene names: 37523117

Gene position: 3745721-3745020 (Counterclockwise)

Preceding gene: 37523119

Following gene: 37523114

Centisome position: 80.4

GC content: 62.82

Gene sequence:

>702_bases
ATGGCCAAGCCCGTTGTTGTCGCCCCGTCGATTTTGTCGGCCGACTTTGCCCGCCTCGGCGAGGAGATTCATGCCATTGA
TGAAGCCGGAGCAGACTGGATCCACGTCGATGTCATGGACGGGCGCTTTGTGCCCAACATCACGATTGGACCGCTCATCG
TCAAGGCGATCCGGCCGGTGACCCAGAAAGTGCTCGATGTGCACCTGATGATTGTCGAGCCCGAGAAGTACATCGCCGAT
TTTGCCAAGGCGGGTGCCGACATCATCACCGTCCATTGCGAACACAACTCGACGGTGCACCTGCACCGGGCGCTCTCGCA
GATCAAAGAACTGGGCAAACAGGCGGGTGTGTCGCTCAATCCGTCCACACCTTTGAGCCTCATCGAGTACGTCCTCGACC
TGTGCGACTTGGTACTCGTCATGAGCGTCAACCCCGGCTTCGGCGGCCAAAGCTTCATTCCGCAGGTGCTGCCCAAGATT
GCCCGGCTCAAGTCGATGTGCGAGGAGCGCGGCCTCGACCCGTGGATCGAAGTGGACGGCGGCCTGAAGCCTTCCAACAC
CTGGCAGGTGCTCGAGGTGGGTGCCAACGCCATCGTCTCGGGCTCGGGAGTGTTTGGGGTCGGCCCGGCCCGCTACGCCG
AGGCGATCGAAGGGGTGCGCGCCAGCCACCGCCCGGCGGTGGAAGTGGCCGCCCAGGTGTAG

Upstream 100 bases:

>100_bases
TTAGCTGATTGTTTACTTCGCCATAACCTGACGGCTGAACCGGTCCCCTTAATTAAAAGTAGTAAACTGGGGGGCAGACG
CACCAGGAGGTTCTCGACCC

Downstream 100 bases:

>100_bases
CGCCTGCCTATTCTTCGAGGAGCACCACCGCGTGACAGGCCATAGCAAGGCCTTCGCCCACGGGGCCGAGGCCCTCGTTG
GTCGTGGCCTTGACGCTCAA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAKPVVVAPSILSADFARLGEEIHAIDEAGADWIHVDVMDGRFVPNITIGPLIVKAIRPVTQKVLDVHLMIVEPEKYIAD
FAKAGADIITVHCEHNSTVHLHRALSQIKELGKQAGVSLNPSTPLSLIEYVLDLCDLVLVMSVNPGFGGQSFIPQVLPKI
ARLKSMCEERGLDPWIEVDGGLKPSNTWQVLEVGANAIVSGSGVFGVGPARYAEAIEGVRASHRPAVEVAAQV

Sequences:

>Translated_233_residues
MAKPVVVAPSILSADFARLGEEIHAIDEAGADWIHVDVMDGRFVPNITIGPLIVKAIRPVTQKVLDVHLMIVEPEKYIAD
FAKAGADIITVHCEHNSTVHLHRALSQIKELGKQAGVSLNPSTPLSLIEYVLDLCDLVLVMSVNPGFGGQSFIPQVLPKI
ARLKSMCEERGLDPWIEVDGGLKPSNTWQVLEVGANAIVSGSGVFGVGPARYAEAIEGVRASHRPAVEVAAQV
>Mature_232_residues
AKPVVVAPSILSADFARLGEEIHAIDEAGADWIHVDVMDGRFVPNITIGPLIVKAIRPVTQKVLDVHLMIVEPEKYIADF
AKAGADIITVHCEHNSTVHLHRALSQIKELGKQAGVSLNPSTPLSLIEYVLDLCDLVLVMSVNPGFGGQSFIPQVLPKIA
RLKSMCEERGLDPWIEVDGGLKPSNTWQVLEVGANAIVSGSGVFGVGPARYAEAIEGVRASHRPAVEVAAQV

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=207, Percent_Identity=39.1304347826087, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI219879828, Length=207, Percent_Identity=36.231884057971, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI24307923, Length=157, Percent_Identity=33.1210191082803, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1789788, Length=220, Percent_Identity=47.7272727272727, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1790523, Length=201, Percent_Identity=39.8009950248756, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1790754, Length=207, Percent_Identity=29.4685990338164, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=201, Percent_Identity=39.8009950248756, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6322341, Length=219, Percent_Identity=41.5525114155251, Blast_Score=158, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24586301, Length=215, Percent_Identity=39.5348837209302, Blast_Score=150, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24959; Mature: 24828

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPVVVAPSILSADFARLGEEIHAIDEAGADWIHVDVMDGRFVPNITIGPLIVKAIRPV
CCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHH
TQKVLDVHLMIVEPEKYIADFAKAGADIITVHCEHNSTVHLHRALSQIKELGKQAGVSLN
HHHHHHEEEEEECCHHHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCC
PSTPLSLIEYVLDLCDLVLVMSVNPGFGGQSFIPQVLPKIARLKSMCEERGLDPWIEVDG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
GLKPSNTWQVLEVGANAIVSGSGVFGVGPARYAEAIEGVRASHRPAVEVAAQV
CCCCCCCHHHEEECCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
AKPVVVAPSILSADFARLGEEIHAIDEAGADWIHVDVMDGRFVPNITIGPLIVKAIRPV
CCCEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHH
TQKVLDVHLMIVEPEKYIADFAKAGADIITVHCEHNSTVHLHRALSQIKELGKQAGVSLN
HHHHHHEEEEEECCHHHHHHHHHCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCC
PSTPLSLIEYVLDLCDLVLVMSVNPGFGGQSFIPQVLPKIARLKSMCEERGLDPWIEVDG
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
GLKPSNTWQVLEVGANAIVSGSGVFGVGPARYAEAIEGVRASHRPAVEVAAQV
CCCCCCCHHHEEECCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]