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The map label for this gene is dapL [H]

Identifier: 37523037

GI number: 37523037

Start: 3676775

End: 3677950

Strand: Direct

Name: dapL [H]

Synonym: glr3468

Alternate gene names: 37523037

Gene position: 3676775-3677950 (Clockwise)

Preceding gene: 37523032

Following gene: 37523041

Centisome position: 78.92

GC content: 65.73

Gene sequence:

>1176_bases
ATGCGTTTGGCAACCCGGCTGGAGAAGCTCCAGTCCAACGTGTTTAGCTTGATGGACGAGGCCAAGGCCAGAGCCCGCCG
AGCCGGCCTCGAAGTGGTGGACCTGTCGCTCGGTTCGTCGGACCTTTCCCCCCCGGCCCACGCGCTGGAGCGCATCCGCG
AGTCGATTCTCGATCCGACTTCCCACGGCTATTTGCTCTTTCAGGGCACCCGCTCCTTCCGCGAAGCCTGCGCCGCCTGG
TACGAACGCCGCTACGGTCTGGCGCTCGACCCGGAGACCGAAATTCTGCCGCTCATCGGTTCTCAAGAAGGTACCGCCCA
CATCCCGCTCGCGGTGCTCGATCCGGGCGATGTGGCACTATTGACGGATCCGGGTTATCCGTCCCACGAGGGGGGAGTGC
ACCTAGCGGGCGGTCAGATCTATCCGCTGGCCCTCAGGCCCGAGACGGGCTATCTACCGCAACTGGAGCAGATCCCCGAG
GAAGTGCTGGAGCGCAGCCGCCTGCTGGTACTGAGCTATCCCCACAATCCCACCGCCGCCACGGCGACCCTCGCCTACTT
CGAGCGGGCAGTCGCCTTTTGCCGCGCCCACGACATCGTCCTGGTCCACGATTTTCCCTACGCCGACTTTCACCTGTCCG
GCGAGCAGCCGCCCTCGATTTTGCAGGCCGACCGCGAGCGGGCCGTGGCGATCGAATTTTTCAGCCTCTCCAAGTCGTTC
CACATGGGAGGCTTTCGCATCGGCTTCGCCGTCGGCAACCGCGATCTTGTCGCCGCCCTGCGCCAGGTGAAGGCGAGCAT
CGATTTCAACCAGTACCGCGGCATCTTAGACGGGGCGGAAGCGGCCCTGCGCGGTCCGCAGGACTATGTGCGCGAGGCGG
TGGCCGTCTTTCGTGCTCGTCGCGACCGGGCGGTGGCGGCCCTCGCCCAGGCCGGCTGGCAGGTACCTGCCCCCGAGGCG
ACGATGTACCTGTGGGCGGCGCTACCGGAGTGCTGGCGCGGTTCTTCGGCCGAATTTTGCATCCGGCTGGTGGAGCAAAC
GGGCGTGGCCCTCGCCCCCGGCTCCGGGTTCGGTTCCTCCGGTGAAGGCTACGTGCGCTTCGCACTGGTGCGCTCGGAGG
ACATGCTCGAACGGGCAATTGCGCAGATTGCCGGGTTTTTGCAGAGAAGCTGTTAG

Upstream 100 bases:

>100_bases
AATAAGGAGAGAACCGCAGTGGACAGCCACCCACTTGGCGGGTGGTGTTGATGTGCAGCCGGAAAAACGCGGTAGGATAG
CGAAGTATCCAGGACTACAT

Downstream 100 bases:

>100_bases
AGCAGGTGTCACGGTAAAACTGCTCCCCGCCCAGGTTTCCAGCTGCCCTTCTGGGCGCAGCGCACACGCAGAACTGTGCC
GCAGTCGACACGCATCGTGC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRLATRLEKLQSNVFSLMDEAKARARRAGLEVVDLSLGSSDLSPPAHALERIRESILDPTSHGYLLFQGTRSFREACAAW
YERRYGLALDPETEILPLIGSQEGTAHIPLAVLDPGDVALLTDPGYPSHEGGVHLAGGQIYPLALRPETGYLPQLEQIPE
EVLERSRLLVLSYPHNPTAATATLAYFERAVAFCRAHDIVLVHDFPYADFHLSGEQPPSILQADRERAVAIEFFSLSKSF
HMGGFRIGFAVGNRDLVAALRQVKASIDFNQYRGILDGAEAALRGPQDYVREAVAVFRARRDRAVAALAQAGWQVPAPEA
TMYLWAALPECWRGSSAEFCIRLVEQTGVALAPGSGFGSSGEGYVRFALVRSEDMLERAIAQIAGFLQRSC

Sequences:

>Translated_391_residues
MRLATRLEKLQSNVFSLMDEAKARARRAGLEVVDLSLGSSDLSPPAHALERIRESILDPTSHGYLLFQGTRSFREACAAW
YERRYGLALDPETEILPLIGSQEGTAHIPLAVLDPGDVALLTDPGYPSHEGGVHLAGGQIYPLALRPETGYLPQLEQIPE
EVLERSRLLVLSYPHNPTAATATLAYFERAVAFCRAHDIVLVHDFPYADFHLSGEQPPSILQADRERAVAIEFFSLSKSF
HMGGFRIGFAVGNRDLVAALRQVKASIDFNQYRGILDGAEAALRGPQDYVREAVAVFRARRDRAVAALAQAGWQVPAPEA
TMYLWAALPECWRGSSAEFCIRLVEQTGVALAPGSGFGSSGEGYVRFALVRSEDMLERAIAQIAGFLQRSC
>Mature_391_residues
MRLATRLEKLQSNVFSLMDEAKARARRAGLEVVDLSLGSSDLSPPAHALERIRESILDPTSHGYLLFQGTRSFREACAAW
YERRYGLALDPETEILPLIGSQEGTAHIPLAVLDPGDVALLTDPGYPSHEGGVHLAGGQIYPLALRPETGYLPQLEQIPE
EVLERSRLLVLSYPHNPTAATATLAYFERAVAFCRAHDIVLVHDFPYADFHLSGEQPPSILQADRERAVAIEFFSLSKSF
HMGGFRIGFAVGNRDLVAALRQVKASIDFNQYRGILDGAEAALRGPQDYVREAVAVFRARRDRAVAALAQAGWQVPAPEA
TMYLWAALPECWRGSSAEFCIRLVEQTGVALAPGSGFGSSGEGYVRFALVRSEDMLERAIAQIAGFLQRSC

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=420, Percent_Identity=22.6190476190476, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI56713254, Length=420, Percent_Identity=22.6190476190476, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI95147551, Length=387, Percent_Identity=23.7726098191214, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI169881279, Length=387, Percent_Identity=23.7726098191214, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788722, Length=388, Percent_Identity=39.4329896907216, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1786816, Length=376, Percent_Identity=26.8617021276596, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788627, Length=258, Percent_Identity=26.7441860465116, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=389, Percent_Identity=21.8508997429306, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=389, Percent_Identity=21.5938303341902, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=390, Percent_Identity=20.5128205128205, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=22.7513227513227, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=391, Percent_Identity=19.4373401534527, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573069, Length=405, Percent_Identity=22.7160493827161, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646114, Length=405, Percent_Identity=22.7160493827161, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573067, Length=405, Percent_Identity=22.7160493827161, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573065, Length=405, Percent_Identity=22.7160493827161, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=22.3404255319149, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 42864; Mature: 42864

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLATRLEKLQSNVFSLMDEAKARARRAGLEVVDLSLGSSDLSPPAHALERIRESILDPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
SHGYLLFQGTRSFREACAAWYERRYGLALDPETEILPLIGSQEGTAHIPLAVLDPGDVAL
CCCEEEEECCHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCCEECCEEEECCCCEEE
LTDPGYPSHEGGVHLAGGQIYPLALRPETGYLPQLEQIPEEVLERSRLLVLSYPHNPTAA
EECCCCCCCCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHH
TATLAYFERAVAFCRAHDIVLVHDFPYADFHLSGEQPPSILQADRERAVAIEFFSLSKSF
HHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCCHHHHHHCCCCEEEEEEEHHCCCC
HMGGFRIGFAVGNRDLVAALRQVKASIDFNQYRGILDGAEAALRGPQDYVREAVAVFRAR
CCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RDRAVAALAQAGWQVPAPEATMYLWAALPECWRGSSAEFCIRLVEQTGVALAPGSGFGSS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCC
GEGYVRFALVRSEDMLERAIAQIAGFLQRSC
CCCEEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLATRLEKLQSNVFSLMDEAKARARRAGLEVVDLSLGSSDLSPPAHALERIRESILDPT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCC
SHGYLLFQGTRSFREACAAWYERRYGLALDPETEILPLIGSQEGTAHIPLAVLDPGDVAL
CCCEEEEECCHHHHHHHHHHHHHCCCCEECCCCCEEEEECCCCCCEECCEEEECCCCEEE
LTDPGYPSHEGGVHLAGGQIYPLALRPETGYLPQLEQIPEEVLERSRLLVLSYPHNPTAA
EECCCCCCCCCCEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHH
TATLAYFERAVAFCRAHDIVLVHDFPYADFHLSGEQPPSILQADRERAVAIEFFSLSKSF
HHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCCHHHHHHCCCCEEEEEEEHHCCCC
HMGGFRIGFAVGNRDLVAALRQVKASIDFNQYRGILDGAEAALRGPQDYVREAVAVFRAR
CCCCEEEEEEECCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RDRAVAALAQAGWQVPAPEATMYLWAALPECWRGSSAEFCIRLVEQTGVALAPGSGFGSS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCC
GEGYVRFALVRSEDMLERAIAQIAGFLQRSC
CCCEEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA