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The map label for this gene is txlA [H]

Identifier: 37522957

GI number: 37522957

Start: 3595387

End: 3595740

Strand: Direct

Name: txlA [H]

Synonym: glr3388

Alternate gene names: 37522957

Gene position: 3595387-3595740 (Clockwise)

Preceding gene: 37522955

Following gene: 37522958

Centisome position: 77.17

GC content: 62.43

Gene sequence:

>354_bases
ATGGTGACGATGAAACGCAGAGCGCTGGCGGGGGCTTTGGCGGCGGCGGTGGCGGGGTGGCCCGTGACGGCCAGTACCGG
CAAGCCGCAACTGCTCGAATTTTGGGCTTCGTGGTGCGGCGTATGCCGGGCCATGGAGCCGACGATGGCGGCTCTGAAGG
AGCGCTGGGGCAAGCAGGTGGATATCCGCATCGTCGATGTGGACGAACCCGAGAATGCCGCCCTGGTGCGCCGGTACAAG
ATTTTCGGAACGGCGACTTTTGTGTTGCTCGACGGTCGGGGCAAAGAAGCCTACCGCGGCAGCGGTCAGATTCCCCAGAC
GGTTTTCGAGTCCGAGTTCAAAAAAGTGCTTTGA

Upstream 100 bases:

>100_bases
ATTTGCGGCGCTTCTCCGCCTGCGGCGGGCGGCGCCGCACGGGACGGCTGGGCATTGGGTCCGGCGCAATGTATCGTAAA
AAACGGGGGGACCGTTTCGG

Downstream 100 bases:

>100_bases
AGCTAAAAAAGGCGTGCACCCATGCGTAAATTGCTGCTGAAATCCTCTTTGCTCTTTGCTCTCCTGCTCGCAGGTCCACA
GGCGGCCCTGCTGGCTGCTC

Product: thiol:disulfide interchange protein; TrxA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MVTMKRRALAGALAAAVAGWPVTASTGKPQLLEFWASWCGVCRAMEPTMAALKERWGKQVDIRIVDVDEPENAALVRRYK
IFGTATFVLLDGRGKEAYRGSGQIPQTVFESEFKKVL

Sequences:

>Translated_117_residues
MVTMKRRALAGALAAAVAGWPVTASTGKPQLLEFWASWCGVCRAMEPTMAALKERWGKQVDIRIVDVDEPENAALVRRYK
IFGTATFVLLDGRGKEAYRGSGQIPQTVFESEFKKVL
>Mature_117_residues
MVTMKRRALAGALAAAVAGWPVTASTGKPQLLEFWASWCGVCRAMEPTMAALKERWGKQVDIRIVDVDEPENAALVRRYK
IFGTATFVLLDGRGKEAYRGSGQIPQTVFESEFKKVL

Specific function: Required for disulfide bond formation in some proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 12918; Mature: 12918

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTMKRRALAGALAAAVAGWPVTASTGKPQLLEFWASWCGVCRAMEPTMAALKERWGKQV
CCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEE
DIRIVDVDEPENAALVRRYKIFGTATFVLLDGRGKEAYRGSGQIPQTVFESEFKKVL
EEEEEECCCCCCHHHHHHHHEECEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVTMKRRALAGALAAAVAGWPVTASTGKPQLLEFWASWCGVCRAMEPTMAALKERWGKQV
CCCCHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEE
DIRIVDVDEPENAALVRRYKIFGTATFVLLDGRGKEAYRGSGQIPQTVFESEFKKVL
EEEEEECCCCCCHHHHHHHHEECEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]