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The map label for this gene is cheR [H]

Identifier: 37522899

GI number: 37522899

Start: 3535451

End: 3536332

Strand: Direct

Name: cheR [H]

Synonym: glr3330

Alternate gene names: 37522899

Gene position: 3535451-3536332 (Clockwise)

Preceding gene: 37522898

Following gene: 37522905

Centisome position: 75.88

GC content: 65.76

Gene sequence:

>882_bases
ATGACGGACAATTTCAAGCCTCTTTCTGCTGCGGGCCTGCCGGCGCGTGTCGCCAAGCTCTCCACCCCCGCCCCACGGGG
GGAGGCTGCGGCCGAAGCGATCGATGAAGAGGAGGCGGGGTGGAACGGTTTTTGCCTCTGGCTGGCAACCGTCTCCAACA
TCGATATTTTTGCTTACAAATCGCACCAGTTGCACCAGCGGTTGGTGATTCGCCGCCAGTTGGCCGGCGTGGAGAGTTGG
GCGGATTACCGCCGCCATCTGCTCGATTGCCCGCAGGCTTTTGCCCGGTTGCGCGAGAGCCTGGTCACCTCGGTGAGCAG
TTTCTTTCGCGATCCCGAGCAGTGGCAGGTTCTGGAGAGCAGGGTACTGCCGCGGTTGGCCGGAGGCGGGCCGCTGAGCG
CCTGGTCGGTGGGCTGTGCGATGGGGCAAGAACCGTACTCGCTGGCCGTGTGCCTCGATGGGGCCGGGCGGCTTGCGGGC
AGCAAGCTGGTGGGCAGCGACTGCAGCGCGGCGGCGATCGAGCAGGCGCGCCGGGGTGTCTACCGGTCGGCCCTCGAAAA
AACGATTCCCGAGCGCCTGCATCCTTACGCGCAAGCGGCGGACGGTGTATATACGCTCTGTGAGCCCCTGCGCCGGGCGG
TGGAGTTTCGCTGCGAGGATGTCTTTAGGCGGTCATTCGATGGCGGCTGGGATCTGATTTTTTGCCGCAACGTGTTGATT
TACCTCAACGAGGGCGCCCAACGCCGCCTGTTGCGCCGGCTCGCCCACGCCCTGCGCCCCGGGGGCGTGCTCTTTGTCGG
CCGCTCCGAGCGCGTGACGCAGCCGGAAGTGCTGGGTCTTGCGGTTACGACGCCGTATCTGTACCGGCGGGTGGCCCCAT
GA

Upstream 100 bases:

>100_bases
CCTTTGAGCCTGTGGTGTTTGTCCGTCCGTCGCCGATAATATCGAAGGCGGCCCATCGGATCGGCCTCCGCGCCGACCTT
GTATATTTTCCTCTCCGGTT

Downstream 100 bases:

>100_bases
GCACAGCCCTCGCTGCGGCCCGAGCCCGCCTGCCTTGAGAGCCTTGCCGCCCAACACCAGGGTACCGTAACGTCTGCTGC
ACCGGCCTTCACGGCGATTT

Product: chemotaxis protein methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTDNFKPLSAAGLPARVAKLSTPAPRGEAAAEAIDEEEAGWNGFCLWLATVSNIDIFAYKSHQLHQRLVIRRQLAGVESW
ADYRRHLLDCPQAFARLRESLVTSVSSFFRDPEQWQVLESRVLPRLAGGGPLSAWSVGCAMGQEPYSLAVCLDGAGRLAG
SKLVGSDCSAAAIEQARRGVYRSALEKTIPERLHPYAQAADGVYTLCEPLRRAVEFRCEDVFRRSFDGGWDLIFCRNVLI
YLNEGAQRRLLRRLAHALRPGGVLFVGRSERVTQPEVLGLAVTTPYLYRRVAP

Sequences:

>Translated_293_residues
MTDNFKPLSAAGLPARVAKLSTPAPRGEAAAEAIDEEEAGWNGFCLWLATVSNIDIFAYKSHQLHQRLVIRRQLAGVESW
ADYRRHLLDCPQAFARLRESLVTSVSSFFRDPEQWQVLESRVLPRLAGGGPLSAWSVGCAMGQEPYSLAVCLDGAGRLAG
SKLVGSDCSAAAIEQARRGVYRSALEKTIPERLHPYAQAADGVYTLCEPLRRAVEFRCEDVFRRSFDGGWDLIFCRNVLI
YLNEGAQRRLLRRLAHALRPGGVLFVGRSERVTQPEVLGLAVTTPYLYRRVAP
>Mature_292_residues
TDNFKPLSAAGLPARVAKLSTPAPRGEAAAEAIDEEEAGWNGFCLWLATVSNIDIFAYKSHQLHQRLVIRRQLAGVESWA
DYRRHLLDCPQAFARLRESLVTSVSSFFRDPEQWQVLESRVLPRLAGGGPLSAWSVGCAMGQEPYSLAVCLDGAGRLAGS
KLVGSDCSAAAIEQARRGVYRSALEKTIPERLHPYAQAADGVYTLCEPLRRAVEFRCEDVFRRSFDGGWDLIFCRNVLIY
LNEGAQRRLLRRLAHALRPGGVLFVGRSERVTQPEVLGLAVTTPYLYRRVAP

Specific function: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. CheR is responsible for the chemotactic adaptation to repellents [H]

COG id: COG1352

COG function: function code NT; Methylase of chemotaxis methyl-accepting proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheR-type methyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788193, Length=230, Percent_Identity=30.8695652173913, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022642
- InterPro:   IPR000780
- InterPro:   IPR022641 [H]

Pfam domain/function: PF01739 CheR; PF03705 CheR_N [H]

EC number: =2.1.1.80 [H]

Molecular weight: Translated: 32486; Mature: 32354

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50123 CHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNFKPLSAAGLPARVAKLSTPAPRGEAAAEAIDEEEAGWNGFCLWLATVSNIDIFAYK
CCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCEEEEEC
SHQLHQRLVIRRQLAGVESWADYRRHLLDCPQAFARLRESLVTSVSSFFRDPEQWQVLES
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RVLPRLAGGGPLSAWSVGCAMGQEPYSLAVCLDGAGRLAGSKLVGSDCSAAAIEQARRGV
HHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
YRSALEKTIPERLHPYAQAADGVYTLCEPLRRAVEFRCEDVFRRSFDGGWDLIFCRNVLI
HHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
YLNEGAQRRLLRRLAHALRPGGVLFVGRSERVTQPEVLGLAVTTPYLYRRVAP
HCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHEEEEHHHHHHHHCCC
>Mature Secondary Structure 
TDNFKPLSAAGLPARVAKLSTPAPRGEAAAEAIDEEEAGWNGFCLWLATVSNIDIFAYK
CCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCEEEEEC
SHQLHQRLVIRRQLAGVESWADYRRHLLDCPQAFARLRESLVTSVSSFFRDPEQWQVLES
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RVLPRLAGGGPLSAWSVGCAMGQEPYSLAVCLDGAGRLAGSKLVGSDCSAAAIEQARRGV
HHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHH
YRSALEKTIPERLHPYAQAADGVYTLCEPLRRAVEFRCEDVFRRSFDGGWDLIFCRNVLI
HHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
YLNEGAQRRLLRRLAHALRPGGVLFVGRSERVTQPEVLGLAVTTPYLYRRVAP
HCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8244966; 9384377; 10568751 [H]