Click here to switch to the map view.

The map label for this gene is gap1 [H]

Identifier: 37522894

GI number: 37522894

Start: 3527689

End: 3528720

Strand: Reverse

Name: gap1 [H]

Synonym: gvip457

Alternate gene names: 37522894

Gene position: 3528720-3527689 (Counterclockwise)

Preceding gene: 37522895

Following gene: 37522893

Centisome position: 75.74

GC content: 61.24

Gene sequence:

>1032_bases
ATGAGTGCCGTAAAGATTGCAATCAATGGTTTCGGCCGCATCGGCAGGCTGGTATTGCGGGCGGGTCTGGACAATCCCGA
CCTGGAGTTTGTCGGCATCAACGATCTGGTCCCGCCCGACAACCTCGCTTACTTGCTGAAGCACGACTCTACCCACGGCC
GCTTCAAGGGCACCGTCGAAGCGCACCCGGACGGCATGGTCGTCAACGGCCGATTCATTCCGTGCACGGCGATCAAAAAC
CCGGTCGAACTGCCCTGGGGATCGCTGGGGGTCGATTATGTCGTCGAATCGACAGGGCTGTTTACCGGGTACGACGGGGC
TTCCCACCACCTGGCGGCCGGGGCGCGGCGCGTGGTGATCACCGCTCCGACCAAAGACCCTGAGAAGGTGCCGACGCTGC
TGATGGGCGTCAACCACGACCAATTCGATCCGGACCAAGACTTGATCGTCTCCAATGCCAGCTGCACGACCAACTGCCTG
GCACCGGTGGCTAAGGTGATCCACGAGCGCTTTGGCCTTGCTGAAGGACTGATGACCACCGTGCACGCGATGACTGCGAC
GCAGCCCACTGTGGACGGCCCGAGCAAAAAAGATTGGCGCGGCGGCCGGGGCGCGGCCCAGAACGTTATTCCCTCCTCCA
CCGGGGCGGCCAAGGCAGTGACGCTGGTACTGCCCGAGTTGAAGGGCCGGCTCACCGGCATGGCCTTTCGGGTGCCCGTA
CCGAACGTCTCGGTGGTCGATCTCACCTTCAAGACCGAGCAACCCACCAGCTACAAGGCGATCTGCGCCGCGATGAAAGA
AGCCTCGGAAAACGAACTGGCGGGCATCCTGGGCTACACCGAGGAGCAGGTGGTCTCCAGCGATTTTATCGGCGACGCCC
ATTCGAGCATCTTCGACGCCGGGGCCGGTATCGAACTCAATTCCCAATTTTTTAAAGTGGTCAGCTGGTACGACAACGAG
TGGGGCTACTCCTGCCGGGTAAACGATCTGATCGTCGCGATGGCCCACAAAGAAAAACCCGCCGATTCCTAG

Upstream 100 bases:

>100_bases
TTGCTCGAAAGATAGCAGAACCGGGTTAAAAAAAGATAAATAACCCTGTGCAATACCTGAGGAAGCGCTATTCTCCTGGT
GGCCTCTTCGGATGATGTTT

Downstream 100 bases:

>100_bases
AGGCAGGCGGCTCCAACCCCATCCCAAGGGATTTTTATGCAAGATCGACTGTTCGTCTCGATGGAGCACCCGCGTGCCCT
TCCAGAAACGGATCTGATCA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSAVKIAINGFGRIGRLVLRAGLDNPDLEFVGINDLVPPDNLAYLLKHDSTHGRFKGTVEAHPDGMVVNGRFIPCTAIKN
PVELPWGSLGVDYVVESTGLFTGYDGASHHLAAGARRVVITAPTKDPEKVPTLLMGVNHDQFDPDQDLIVSNASCTTNCL
APVAKVIHERFGLAEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNVIPSSTGAAKAVTLVLPELKGRLTGMAFRVPV
PNVSVVDLTFKTEQPTSYKAICAAMKEASENELAGILGYTEEQVVSSDFIGDAHSSIFDAGAGIELNSQFFKVVSWYDNE
WGYSCRVNDLIVAMAHKEKPADS

Sequences:

>Translated_343_residues
MSAVKIAINGFGRIGRLVLRAGLDNPDLEFVGINDLVPPDNLAYLLKHDSTHGRFKGTVEAHPDGMVVNGRFIPCTAIKN
PVELPWGSLGVDYVVESTGLFTGYDGASHHLAAGARRVVITAPTKDPEKVPTLLMGVNHDQFDPDQDLIVSNASCTTNCL
APVAKVIHERFGLAEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNVIPSSTGAAKAVTLVLPELKGRLTGMAFRVPV
PNVSVVDLTFKTEQPTSYKAICAAMKEASENELAGILGYTEEQVVSSDFIGDAHSSIFDAGAGIELNSQFFKVVSWYDNE
WGYSCRVNDLIVAMAHKEKPADS
>Mature_342_residues
SAVKIAINGFGRIGRLVLRAGLDNPDLEFVGINDLVPPDNLAYLLKHDSTHGRFKGTVEAHPDGMVVNGRFIPCTAIKNP
VELPWGSLGVDYVVESTGLFTGYDGASHHLAAGARRVVITAPTKDPEKVPTLLMGVNHDQFDPDQDLIVSNASCTTNCLA
PVAKVIHERFGLAEGLMTTVHAMTATQPTVDGPSKKDWRGGRGAAQNVIPSSTGAAKAVTLVLPELKGRLTGMAFRVPVP
NVSVVDLTFKTEQPTSYKAICAAMKEASENELAGILGYTEEQVVSSDFIGDAHSSIFDAGAGIELNSQFFKVVSWYDNEW
GYSCRVNDLIVAMAHKEKPADS

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=335, Percent_Identity=59.4029850746269, Blast_Score=407, Evalue=1e-114,
Organism=Homo sapiens, GI7669492, Length=339, Percent_Identity=58.9970501474926, Blast_Score=404, Evalue=1e-113,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=61.5853658536585, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1789295, Length=335, Percent_Identity=36.7164179104478, Blast_Score=228, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17534677, Length=343, Percent_Identity=57.1428571428571, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=56.8513119533528, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17534679, Length=343, Percent_Identity=56.5597667638484, Blast_Score=390, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=57.396449704142, Blast_Score=389, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=59.7597597597598, Blast_Score=407, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=58.9665653495441, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=58.3586626139818, Blast_Score=392, Evalue=1e-110,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=59.4029850746269, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=59.4029850746269, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=59.4029850746269, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=59.4029850746269, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=53.0487804878049, Blast_Score=347, Evalue=5e-96,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36717; Mature: 36586

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVKIAINGFGRIGRLVLRAGLDNPDLEFVGINDLVPPDNLAYLLKHDSTHGRFKGTVE
CCEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEE
AHPDGMVVNGRFIPCTAIKNPVELPWGSLGVDYVVESTGLFTGYDGASHHLAAGARRVVI
ECCCCEEECCEEEEHHHCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHCCCEEEEE
TAPTKDPEKVPTLLMGVNHDQFDPDQDLIVSNASCTTNCLAPVAKVIHERFGLAEGLMTT
ECCCCCHHHHCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHH
VHAMTATQPTVDGPSKKDWRGGRGAAQNVIPSSTGAAKAVTLVLPELKGRLTGMAFRVPV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCEEEEECC
PNVSVVDLTFKTEQPTSYKAICAAMKEASENELAGILGYTEEQVVSSDFIGDAHSSIFDA
CCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHC
GAGIELNSQFFKVVSWYDNEWGYSCRVNDLIVAMAHKEKPADS
CCCCEECHHHEEEEEEECCCCCCEEEHHHEEEEEECCCCCCCC
>Mature Secondary Structure 
SAVKIAINGFGRIGRLVLRAGLDNPDLEFVGINDLVPPDNLAYLLKHDSTHGRFKGTVE
CEEEEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEEEEEEE
AHPDGMVVNGRFIPCTAIKNPVELPWGSLGVDYVVESTGLFTGYDGASHHLAAGARRVVI
ECCCCEEECCEEEEHHHCCCCCCCCCCCCCCCEEEECCCEEECCCCCCCHHHCCCEEEEE
TAPTKDPEKVPTLLMGVNHDQFDPDQDLIVSNASCTTNCLAPVAKVIHERFGLAEGLMTT
ECCCCCHHHHCCEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHH
VHAMTATQPTVDGPSKKDWRGGRGAAQNVIPSSTGAAKAVTLVLPELKGRLTGMAFRVPV
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHCCCCCCEEEEECC
PNVSVVDLTFKTEQPTSYKAICAAMKEASENELAGILGYTEEQVVSSDFIGDAHSSIFDA
CCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHCCCCHHHHHHHC
GAGIELNSQFFKVVSWYDNEWGYSCRVNDLIVAMAHKEKPADS
CCCCEECHHHEEEEEEECCCCCCEEEHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]