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The map label for this gene is ssaB [H]

Identifier: 37522880

GI number: 37522880

Start: 3510442

End: 3511458

Strand: Direct

Name: ssaB [H]

Synonym: glr3311

Alternate gene names: 37522880

Gene position: 3510442-3511458 (Clockwise)

Preceding gene: 37522875

Following gene: 37522881

Centisome position: 75.35

GC content: 64.21

Gene sequence:

>1017_bases
GTGGTGCAGGGCGAAAGGCGTGGACTATGGTTACTTTCTCTGTTGATTGGGTTGCTGTTCGGGGGTTGCGCGGGCGGCCC
GGCCCCCGGCGGTGATGCCCAGGATGCCCAGCAGGGCACCGGCAGTCAGTACGAAGCCTTCCTCAGTGGCGACAAGCCGA
AGGTGGCCGCCACCAGCACCATCCTGGCGGACATGACCCGCACGGTGGCCGGTGACGGCTACAGCATCTACAGTATTTTG
AAGCCCGGCGCCGACCCGCACGTCTACGAGCCCTCACCGGGCGACTCGCGGGTGCTCTCGCGGGCGGACCTGGTGCTCTA
CAACGGCTTCAACCTGGAGCCGCAACTGGTGAAGCTGATCGGGGCCACGCAGAACCCCGCTCCCAAGGTTCCCGTCGCCG
AAGTAGGAGGCATCAAGCCATACAAATTGGAGAAAACGGCGGGCATCGTGGCCGCCGACCCGCACGCCTGGGGTTCGGCG
GCCAATGGTGTGCGGTACGTGAGTGCGATCGAGAAGAGTCTGGTTGAAACTTTTCCGAAGGACAAGGAGCGCTTCGAAGC
CAACGCCGCGAACTACCGCAAGGACCTCGAAGCCCTCGACGGCTGGATCCGGGAGCAAATCGCCACGATCCCCGAGGCCA
ACCGCAAACTGGTCAGCTCCCACGACGCCTTTCAGTACTACGGCCGGGCCTACGGCCTGCCGGTGACGGGTTCAATCTTG
GGAGTGTCCACCGAGGAGGAGCCGAGTGCGCGCAAGATCGCCCAACTCGTCGAAACCATCCGCAAAGAGCAGGTGCGCGC
CGTGTTCATCGAGACTTCCACCGCCCCCGAGCTGTTGCAGTCGCTCGCGCGCGACGCGGGGGTCAAAATCGGCGGCACTC
TCTACTCCGATTCGGTCGGGGCGCAAGGGACGGCGGGGGATACTTACATCAAGATGCTCACCGCCAACACCCGCACGATC
GTCGAAGCACTGGGCGGCACCTACACCGCTTTCGTCCCCCCCTCTGCCAGTAAGTAG

Upstream 100 bases:

>100_bases
AGCAGTGTTACCCATTGCGCACAACCGGGCGCCGGGGTTTGATGGAGAAAGATTTCATGATCTTTTCATGATCTAACCGG
CGTTGTTGGAGGAACAGACG

Downstream 100 bases:

>100_bases
CTCTCTCCCTGACACCTGACAGCCATGCTCACCATCGCCAATCTATCCGTCCGCTACCGCCGCAACCTTGCTCTAAGCGA
GGTGAACCTTGCCGTCGAGC

Product: ABC transporter solute-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Adhesin B; Saliva-binding protein [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVQGERRGLWLLSLLIGLLFGGCAGGPAPGGDAQDAQQGTGSQYEAFLSGDKPKVAATSTILADMTRTVAGDGYSIYSIL
KPGADPHVYEPSPGDSRVLSRADLVLYNGFNLEPQLVKLIGATQNPAPKVPVAEVGGIKPYKLEKTAGIVAADPHAWGSA
ANGVRYVSAIEKSLVETFPKDKERFEANAANYRKDLEALDGWIREQIATIPEANRKLVSSHDAFQYYGRAYGLPVTGSIL
GVSTEEEPSARKIAQLVETIRKEQVRAVFIETSTAPELLQSLARDAGVKIGGTLYSDSVGAQGTAGDTYIKMLTANTRTI
VEALGGTYTAFVPPSASK

Sequences:

>Translated_338_residues
MVQGERRGLWLLSLLIGLLFGGCAGGPAPGGDAQDAQQGTGSQYEAFLSGDKPKVAATSTILADMTRTVAGDGYSIYSIL
KPGADPHVYEPSPGDSRVLSRADLVLYNGFNLEPQLVKLIGATQNPAPKVPVAEVGGIKPYKLEKTAGIVAADPHAWGSA
ANGVRYVSAIEKSLVETFPKDKERFEANAANYRKDLEALDGWIREQIATIPEANRKLVSSHDAFQYYGRAYGLPVTGSIL
GVSTEEEPSARKIAQLVETIRKEQVRAVFIETSTAPELLQSLARDAGVKIGGTLYSDSVGAQGTAGDTYIKMLTANTRTI
VEALGGTYTAFVPPSASK
>Mature_338_residues
MVQGERRGLWLLSLLIGLLFGGCAGGPAPGGDAQDAQQGTGSQYEAFLSGDKPKVAATSTILADMTRTVAGDGYSIYSIL
KPGADPHVYEPSPGDSRVLSRADLVLYNGFNLEPQLVKLIGATQNPAPKVPVAEVGGIKPYKLEKTAGIVAADPHAWGSA
ANGVRYVSAIEKSLVETFPKDKERFEANAANYRKDLEALDGWIREQIATIPEANRKLVSSHDAFQYYGRAYGLPVTGSIL
GVSTEEEPSARKIAQLVETIRKEQVRAVFIETSTAPELLQSLARDAGVKIGGTLYSDSVGAQGTAGDTYIKMLTANTRTI
VEALGGTYTAFVPPSASK

Specific function: Part of an ATP-driven transport system for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in the pathogenesis and infection. It may contribute to the formation and accumulation of dental

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family. Lipoprotein receptor antigen (Lrai) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=274, Percent_Identity=24.8175182481752, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35833; Mature: 35833

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQGERRGLWLLSLLIGLLFGGCAGGPAPGGDAQDAQQGTGSQYEAFLSGDKPKVAATST
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCHHHHHH
ILADMTRTVAGDGYSIYSILKPGADPHVYEPSPGDSRVLSRADLVLYNGFNLEPQLVKLI
HHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCEEEECCCCCCHHHHHHH
GATQNPAPKVPVAEVGGIKPYKLEKTAGIVAADPHAWGSAANGVRYVSAIEKSLVETFPK
CCCCCCCCCCCHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DKERFEANAANYRKDLEALDGWIREQIATIPEANRKLVSSHDAFQYYGRAYGLPVTGSIL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEE
GVSTEEEPSARKIAQLVETIRKEQVRAVFIETSTAPELLQSLARDAGVKIGGTLYSDSVG
ECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCEECCEEECCCCC
AQGTAGDTYIKMLTANTRTIVEALGGTYTAFVPPSASK
CCCCCCCEEEEEEECCHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MVQGERRGLWLLSLLIGLLFGGCAGGPAPGGDAQDAQQGTGSQYEAFLSGDKPKVAATST
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCHHHHHHCCCCCCHHHHHH
ILADMTRTVAGDGYSIYSILKPGADPHVYEPSPGDSRVLSRADLVLYNGFNLEPQLVKLI
HHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHCCEEEECCCCCCHHHHHHH
GATQNPAPKVPVAEVGGIKPYKLEKTAGIVAADPHAWGSAANGVRYVSAIEKSLVETFPK
CCCCCCCCCCCHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
DKERFEANAANYRKDLEALDGWIREQIATIPEANRKLVSSHDAFQYYGRAYGLPVTGSIL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHCCCCCCCCEE
GVSTEEEPSARKIAQLVETIRKEQVRAVFIETSTAPELLQSLARDAGVKIGGTLYSDSVG
ECCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCEECCEEECCCCC
AQGTAGDTYIKMLTANTRTIVEALGGTYTAFVPPSASK
CCCCCCCEEEEEEECCHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1671775; 8419308 [H]