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The map label for this gene is fur [H]

Identifier: 37522873

GI number: 37522873

Start: 3502932

End: 3503393

Strand: Direct

Name: fur [H]

Synonym: glr3304

Alternate gene names: 37522873

Gene position: 3502932-3503393 (Clockwise)

Preceding gene: 37522872

Following gene: 37522874

Centisome position: 75.19

GC content: 59.52

Gene sequence:

>462_bases
ATGGTCAACTCTACCCAATACACATCGGCGGCCCTCAAAGCGGAACTCAATTCGAAGGGCTGGCGGATGACTCCCCAGCG
CGAGACGATTTTGAAGGTGTTCCAGGAGTTGCCGGAGGGCAATCACCTCAATGCCGAGGAGCTGCACGCACGGCTGGAGA
CATCGAGCGGCATCAGCCTTTCGACGGTTTACCGCACGTTGAAGCTGATGGCGCGCATGGGCATCCTGCGCGAGCTTGAA
CTGGCCGAAGGCCACAAGCACTACGAAATCAACCAGCCCTATCCGCACCACCACCACCATCTGGTCTGCGTCAAGTGCTA
CCGCACCATCGAATTTAAGAGCAACCCGATTCTCACCATCGGCTCGAAGGCGGCCACCGAGCGCGGTTTCAAGCTGCTCG
ACTGCCAGCTGACCATCCACGCGGTTTGCCCGGAGTGCCAGCGCTCGATCGTGCCGATCTAG

Upstream 100 bases:

>100_bases
CAATGGATCACATTTATTTAGATCTCTGCCGGTCGGGGTTGCCCATTCCCGGTTCTGCTCGTGTATATTGTCAATAAGCA
AAGCTTTTTGAGAACGGCCC

Downstream 100 bases:

>100_bases
CGGCCCCCGCCCTTAAAATGGGGCGATGATTTCCCGCCGGTTGTTTTCTTTGTGCGCCCTGGGTGGGCTGTGGCCGCTGC
TGCAGCCTGCTTTTGCCCTC

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MVNSTQYTSAALKAELNSKGWRMTPQRETILKVFQELPEGNHLNAEELHARLETSSGISLSTVYRTLKLMARMGILRELE
LAEGHKHYEINQPYPHHHHHLVCVKCYRTIEFKSNPILTIGSKAATERGFKLLDCQLTIHAVCPECQRSIVPI

Sequences:

>Translated_153_residues
MVNSTQYTSAALKAELNSKGWRMTPQRETILKVFQELPEGNHLNAEELHARLETSSGISLSTVYRTLKLMARMGILRELE
LAEGHKHYEINQPYPHHHHHLVCVKCYRTIEFKSNPILTIGSKAATERGFKLLDCQLTIHAVCPECQRSIVPI
>Mature_153_residues
MVNSTQYTSAALKAELNSKGWRMTPQRETILKVFQELPEGNHLNAEELHARLETSSGISLSTVYRTLKLMARMGILRELE
LAEGHKHYEINQPYPHHHHHLVCVKCYRTIEFKSNPILTIGSKAATERGFKLLDCQLTIHAVCPECQRSIVPI

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates genes involved in iron scavenging or photosynthetic electron transport [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=34.3511450381679, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17444; Mature: 17444

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNSTQYTSAALKAELNSKGWRMTPQRETILKVFQELPEGNHLNAEELHARLETSSGISL
CCCCCCHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHH
STVYRTLKLMARMGILRELELAEGHKHYEINQPYPHHHHHLVCVKCYRTIEFKSNPILTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEEEHEEECCCCEEEE
GSKAATERGFKLLDCQLTIHAVCPECQRSIVPI
CCHHHHHCCCEEEEEEEEEEHCCHHHHHCCCCC
>Mature Secondary Structure
MVNSTQYTSAALKAELNSKGWRMTPQRETILKVFQELPEGNHLNAEELHARLETSSGISL
CCCCCCHHHHHHHHHCCCCCCEECCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHH
STVYRTLKLMARMGILRELELAEGHKHYEINQPYPHHHHHLVCVKCYRTIEFKSNPILTI
HHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEEEEEEHEEECCCCEEEE
GSKAATERGFKLLDCQLTIHAVCPECQRSIVPI
CCHHHHHCCCEEEEEEEEEEHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704986 [H]