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The map label for this gene is ruvC

Identifier: 37522869

GI number: 37522869

Start: 3500927

End: 3501448

Strand: Reverse

Name: ruvC

Synonym: gvip456

Alternate gene names: 37522869

Gene position: 3501448-3500927 (Counterclockwise)

Preceding gene: 37522871

Following gene: 37522862

Centisome position: 75.15

GC content: 62.64

Gene sequence:

>522_bases
ATGTGCGGCATGCGGATTCTCGGTCTCGATCCGGGCGTGGCGATCCTCGGTTACGGAGTGCTCGACTTTTTTGACAGCGC
TCCGCCGGTAGTGTGCGACTACGGCATTGTGCAGACCTCGGCAAAAACCGCCTTCGAAGCAAGACTTGCGGCCATCTACG
AGGACATTAATAGTTTATTTTCCGCCCACAAGCCCGACTTGGTTGCTATCGAAAAACTCTTCTTCTACAAGATGGGCAAC
ACGATCTCGGTGGCCCAGGCGCGGGGAGTGGTGCTCCTGTGCGCTGCCCAGCACGGGGTGCCCTATGTCGAATTCAGTCC
GCCCCAGGTCAAACTCGCCCTCACCGGCGACGGCCGCGCCGACAAGCGCGCCATCCAGGAGGCCGTGCAGCGCGAGTTGG
GGTTGATTACCATGCCCAAACCCGACGACGCCGCCGATGCCCTGGCCATCGCCCTGACCGGCTGGTTCCACCACCTGCCC
CCCGCCGCCCGCGAAGCCGTTCCCGCCTACAGCGTCGGTTGA

Upstream 100 bases:

>100_bases
GCCCAGCACATGGTATCTCCTGCAAATATCCATCCCCGACGATAGTAAACCCCTGGAGATTTAGTGTCCGAAGGTTGTAG
TCTGGGCGGTATCTTGCAAA

Downstream 100 bases:

>100_bases
GAGAGCCGCGCTACGAAAGCGAAGGGCCACCCTCGGCGCTTGAGAGCACCGGGGAGGATATTGCCCCGGTGGCGCCCGAC
TCGCCTACGCCCTTCAGTTC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MCGMRILGLDPGVAILGYGVLDFFDSAPPVVCDYGIVQTSAKTAFEARLAAIYEDINSLFSAHKPDLVAIEKLFFYKMGN
TISVAQARGVVLLCAAQHGVPYVEFSPPQVKLALTGDGRADKRAIQEAVQRELGLITMPKPDDAADALAIALTGWFHHLP
PAAREAVPAYSVG

Sequences:

>Translated_173_residues
MCGMRILGLDPGVAILGYGVLDFFDSAPPVVCDYGIVQTSAKTAFEARLAAIYEDINSLFSAHKPDLVAIEKLFFYKMGN
TISVAQARGVVLLCAAQHGVPYVEFSPPQVKLALTGDGRADKRAIQEAVQRELGLITMPKPDDAADALAIALTGWFHHLP
PAAREAVPAYSVG
>Mature_173_residues
MCGMRILGLDPGVAILGYGVLDFFDSAPPVVCDYGIVQTSAKTAFEARLAAIYEDINSLFSAHKPDLVAIEKLFFYKMGN
TISVAQARGVVLLCAAQHGVPYVEFSPPQVKLALTGDGRADKRAIQEAVQRELGLITMPKPDDAADALAIALTGWFHHLP
PAAREAVPAYSVG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=136, Percent_Identity=31.6176470588235, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_GLOVI (Q7NG73)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926246.1
- ProteinModelPortal:   Q7NG73
- SMR:   Q7NG73
- GeneID:   2601702
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.3300
- HOGENOM:   HBG437552
- OMA:   PMQIKLA
- ProtClustDB:   PRK00039
- BioCyc:   GVIO251221:GLL3300-MONOMER
- BRENDA:   3.1.22.4
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18472; Mature: 18472

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGMRILGLDPGVAILGYGVLDFFDSAPPVVCDYGIVQTSAKTAFEARLAAIYEDINSLF
CCCCEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAHKPDLVAIEKLFFYKMGNTISVAQARGVVLLCAAQHGVPYVEFSPPQVKLALTGDGRA
HCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCEEEECCCEEEEEEECCCCH
DKRAIQEAVQRELGLITMPKPDDAADALAIALTGWFHHLPPAAREAVPAYSVG
HHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure
MCGMRILGLDPGVAILGYGVLDFFDSAPPVVCDYGIVQTSAKTAFEARLAAIYEDINSLF
CCCCEEEECCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
SAHKPDLVAIEKLFFYKMGNTISVAQARGVVLLCAAQHGVPYVEFSPPQVKLALTGDGRA
HCCCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEEECCCCCEEEECCCEEEEEEECCCCH
DKRAIQEAVQRELGLITMPKPDDAADALAIALTGWFHHLPPAAREAVPAYSVG
HHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292