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The map label for this gene is engA

Identifier: 37522779

GI number: 37522779

Start: 3418862

End: 3420229

Strand: Reverse

Name: engA

Synonym: gll3210

Alternate gene names: 37522779

Gene position: 3420229-3418862 (Counterclockwise)

Preceding gene: 37522780

Following gene: 37522778

Centisome position: 73.41

GC content: 65.35

Gene sequence:

>1368_bases
ATGCAATTACCAATCGTCGCCATCATTGGACGGCCGAACGTCGGCAAGTCCACGCTGCTCAACCGTTTGGCGGGAGGCAG
CGAAGCCATCGTCTACGACCAGCCGGGGGTCACCCGCGACCGGCTCTACCTGCCGGCCGAATGGTGCGGCTACCGCTTCG
AGGTGGTCGATACCGGCGGGCTGGTCTTCGAAGACAGCGAAGTCTTTTTGCCGCTGATTCGCGAGCAGGTCGAAATCGCC
CTGGCCGAAGCGGCGGCGGTCCTGTTCGTGGTGGATGGCCAGCAGGGGATCACCGGCGGCGATCGGGAGGTGGCCGACTG
GCTGCGCGGGCGCAAACCGCCCGTGCTCATTGTGGCGAACAAACTGGAGGAGCCTTCGACGGCCCTGAGCCTGGCGGCCG
AATTTTATGCACTCGGTTTGGGCGAACCCTACGCCGTCTCGGCCATCCACGGTTCGGGCACGGGCGATCTGCTCGACGCG
CTGGTGGCGGTGCTTCCCAAAGATCAGCCCGAAGAACAGGAACTGCCCGAACTGCGCGTGTCCATTGTCGGGCGGCCCAA
CGTCGGCAAATCGAGCCTGCTCAATGCCCTGGTGGGTGGGGAGCACCCGCGCTCGATGGTCTCGGAGGTCGCCGGCACCA
CCCGCGACGCCATCGACACGCTCGTCGAGCACGGCGAGCGGCGCTACCGCCTGATCGACACGGCGGGCATCCGCCGCAAA
TCCCGCGTCGACTACGGACCGGAGGCGTTCGGGGTGACGCGGGCGATTCGCGCCATCCGCCGCGCCGATGTGGTGGTGCT
GGTCGTCGACGCCACCGAGGGCATCCACGATCAAGAAAGAAACCTCGCAGCCAAGATCGCTTCGGCGGGGCGCGCCTGCG
TGCTGGTGGTCAACAAATGGGATGCCATCGAAAAGGACACCTACACGATGAACCACTACCGCGACGAGATGCGCCGCGAA
CTGGATTTCGTCGAATGGGCGCCGGTGGTTTTTACCAGTGCCCTCACCGGCCAGCGGGTCGAAAAGATCTTCGATGCCAT
CGATGCCGCCGCCGGGCAGCACCAGCGCCGTGTCTCCACCTCGGTGCTCAACGAAGCGCTGCAGGATGCGCTGCTGTGGC
GCTCGCCCCCTGCCAGCCGCCAGGGGCGCCAGGGCAAGGTTTACTACGCCACCCAGATCGCCACCAACCCGCCCACCTTC
GTGCTTTTTGTCAACGACACCAAGCTCTTCAAAGAAGGCTACCGCCGCTATCTCGAAGGGCAGTTCCGCGGTTCGCTGGG
CTTCGAAGGCTCGCCGGTGCGCTTTATCTTCCGGGGTAAACCCGAGCGCGAGGCAAACCGCACCGCCCGCAAAAGCGAGC
CGGTCTGA

Upstream 100 bases:

>100_bases
CTCCGTCGGCTCGCCCGGCGCAAAGGCTGGCTCGCCTGCCGCTGGCCCCGCCAGGCGTGAGAACGCACCTGCCGCCTCGA
TGGGCTAGCATAGTCTGGCT

Downstream 100 bases:

>100_bases
TGCGCACCGCCCTCAAGGAGTGGGCGGTCGTCTGCGAAGCCCTCGCCCGGGGCGAACAGAGCATCCTGTTGCGCAAAGGC
GGCATCCGCGAGCGCCGCGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MQLPIVAIIGRPNVGKSTLLNRLAGGSEAIVYDQPGVTRDRLYLPAEWCGYRFEVVDTGGLVFEDSEVFLPLIREQVEIA
LAEAAAVLFVVDGQQGITGGDREVADWLRGRKPPVLIVANKLEEPSTALSLAAEFYALGLGEPYAVSAIHGSGTGDLLDA
LVAVLPKDQPEEQELPELRVSIVGRPNVGKSSLLNALVGGEHPRSMVSEVAGTTRDAIDTLVEHGERRYRLIDTAGIRRK
SRVDYGPEAFGVTRAIRAIRRADVVVLVVDATEGIHDQERNLAAKIASAGRACVLVVNKWDAIEKDTYTMNHYRDEMRRE
LDFVEWAPVVFTSALTGQRVEKIFDAIDAAAGQHQRRVSTSVLNEALQDALLWRSPPASRQGRQGKVYYATQIATNPPTF
VLFVNDTKLFKEGYRRYLEGQFRGSLGFEGSPVRFIFRGKPEREANRTARKSEPV

Sequences:

>Translated_455_residues
MQLPIVAIIGRPNVGKSTLLNRLAGGSEAIVYDQPGVTRDRLYLPAEWCGYRFEVVDTGGLVFEDSEVFLPLIREQVEIA
LAEAAAVLFVVDGQQGITGGDREVADWLRGRKPPVLIVANKLEEPSTALSLAAEFYALGLGEPYAVSAIHGSGTGDLLDA
LVAVLPKDQPEEQELPELRVSIVGRPNVGKSSLLNALVGGEHPRSMVSEVAGTTRDAIDTLVEHGERRYRLIDTAGIRRK
SRVDYGPEAFGVTRAIRAIRRADVVVLVVDATEGIHDQERNLAAKIASAGRACVLVVNKWDAIEKDTYTMNHYRDEMRRE
LDFVEWAPVVFTSALTGQRVEKIFDAIDAAAGQHQRRVSTSVLNEALQDALLWRSPPASRQGRQGKVYYATQIATNPPTF
VLFVNDTKLFKEGYRRYLEGQFRGSLGFEGSPVRFIFRGKPEREANRTARKSEPV
>Mature_455_residues
MQLPIVAIIGRPNVGKSTLLNRLAGGSEAIVYDQPGVTRDRLYLPAEWCGYRFEVVDTGGLVFEDSEVFLPLIREQVEIA
LAEAAAVLFVVDGQQGITGGDREVADWLRGRKPPVLIVANKLEEPSTALSLAAEFYALGLGEPYAVSAIHGSGTGDLLDA
LVAVLPKDQPEEQELPELRVSIVGRPNVGKSSLLNALVGGEHPRSMVSEVAGTTRDAIDTLVEHGERRYRLIDTAGIRRK
SRVDYGPEAFGVTRAIRAIRRADVVVLVVDATEGIHDQERNLAAKIASAGRACVLVVNKWDAIEKDTYTMNHYRDEMRRE
LDFVEWAPVVFTSALTGQRVEKIFDAIDAAAGQHQRRVSTSVLNEALQDALLWRSPPASRQGRQGKVYYATQIATNPPTF
VLFVNDTKLFKEGYRRYLEGQFRGSLGFEGSPVRFIFRGKPEREANRTARKSEPV

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=476, Percent_Identity=38.8655462184874, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1788919, Length=173, Percent_Identity=31.2138728323699, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=44.2105263157895, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=93, Percent_Identity=43.010752688172, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=227, Percent_Identity=25.9911894273128, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_GLOVI (Q7NGF9)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926156.1
- ProteinModelPortal:   Q7NGF9
- SMR:   Q7NGF9
- GeneID:   2601611
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll3210
- NMPDR:   fig|251221.1.peg.3210
- HOGENOM:   HBG592135
- OMA:   KCEKAFD
- ProtClustDB:   PRK00093
- BioCyc:   GVIO251221:GLL3210-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 50149; Mature: 50149

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPIVAIIGRPNVGKSTLLNRLAGGSEAIVYDQPGVTRDRLYLPAEWCGYRFEVVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECHHHHCEEEEEEECCC
LVFEDSEVFLPLIREQVEIALAEAAAVLFVVDGQQGITGGDREVADWLRGRKPPVLIVAN
EEEECCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEC
KLEEPSTALSLAAEFYALGLGEPYAVSAIHGSGTGDLLDALVAVLPKDQPEEQELPELRV
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHCCCEEE
SIVGRPNVGKSSLLNALVGGEHPRSMVSEVAGTTRDAIDTLVEHGERRYRLIDTAGIRRK
EEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCC
SRVDYGPEAFGVTRAIRAIRRADVVVLVVDATEGIHDQERNLAAKIASAGRACVLVVNKW
CCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECC
DAIEKDTYTMNHYRDEMRRELDFVEWAPVVFTSALTGQRVEKIFDAIDAAAGQHQRRVST
CCCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SVLNEALQDALLWRSPPASRQGRQGKVYYATQIATNPPTFVLFVNDTKLFKEGYRRYLEG
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHCC
QFRGSLGFEGSPVRFIFRGKPEREANRTARKSEPV
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MQLPIVAIIGRPNVGKSTLLNRLAGGSEAIVYDQPGVTRDRLYLPAEWCGYRFEVVDTGG
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCEEEECHHHHCEEEEEEECCC
LVFEDSEVFLPLIREQVEIALAEAAAVLFVVDGQQGITGGDREVADWLRGRKPPVLIVAN
EEEECCHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEEC
KLEEPSTALSLAAEFYALGLGEPYAVSAIHGSGTGDLLDALVAVLPKDQPEEQELPELRV
CCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHCCCEEE
SIVGRPNVGKSSLLNALVGGEHPRSMVSEVAGTTRDAIDTLVEHGERRYRLIDTAGIRRK
EEECCCCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCCC
SRVDYGPEAFGVTRAIRAIRRADVVVLVVDATEGIHDQERNLAAKIASAGRACVLVVNKW
CCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEEECC
DAIEKDTYTMNHYRDEMRRELDFVEWAPVVFTSALTGQRVEKIFDAIDAAAGQHQRRVST
CCCCCCCEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
SVLNEALQDALLWRSPPASRQGRQGKVYYATQIATNPPTFVLFVNDTKLFKEGYRRYLEG
HHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHHHHHHHHHHCC
QFRGSLGFEGSPVRFIFRGKPEREANRTARKSEPV
CCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14621292