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The map label for this gene is 37522626

Identifier: 37522626

GI number: 37522626

Start: 3251302

End: 3251715

Strand: Direct

Name: 37522626

Synonym: glr3057

Alternate gene names: NA

Gene position: 3251302-3251715 (Clockwise)

Preceding gene: 37522623

Following gene: 37522627

Centisome position: 69.79

GC content: 64.25

Gene sequence:

>414_bases
GTGGGTTTGAGCGCTCTAGATACGCTGGTCTGGCCGGGTCTGGTCACCGTTGCCGCGCTGGTGGTCTACTATGGCCTTTC
GTTGAATGTCGGCCGCGCCCGTGTGCGCTACGGCGTTGCACCACCCGAGACCAACGGCAATCCCGACTTCGAGCGGGTAT
TGCGTGTCCAGGAGAACACTACCGAGCAACTGGTGCTGTTCCTGCCGTCGCTATGGCTGTACGCGCTGTTTGTCAATCCG
CTGTGGGCAGCCGTCCTGGGTAGTGTCTGGGTTGTCGGGCGGGTGCTGTACGCACTCGGCTACTACGAGGCTTCCGAGCG
GCGCACCCCCGGCTTTGCCGTCTCCGTCGTCGCCACGCTCATTTTGCTGGGCGGCGCGCTGGTGGGACTGTTGCGGCGGC
TGGTTCTCCCGTGA

Upstream 100 bases:

>100_bases
GCATGGCAATCGCCGGCGACAGCGCCCGCGGTGGGGGGCGAGTCTGTCCATCCTACGCCAGGGGCTTGTGCGAGACTGGG
ATAGCTGCACCGTTGGCGAG

Downstream 100 bases:

>100_bases
CCTGCCGATGACCGCCGCGTTTTTGCCCCCGGGTGCCCGTATCCTGAGTGAACCCGGTTCGCTGGAGATGGCGCGGCGGC
TCGAGCTGGTGTCGGTACGG

Product: glutathione S-transferase

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MGLSALDTLVWPGLVTVAALVVYYGLSLNVGRARVRYGVAPPETNGNPDFERVLRVQENTTEQLVLFLPSLWLYALFVNP
LWAAVLGSVWVVGRVLYALGYYEASERRTPGFAVSVVATLILLGGALVGLLRRLVLP

Sequences:

>Translated_137_residues
MGLSALDTLVWPGLVTVAALVVYYGLSLNVGRARVRYGVAPPETNGNPDFERVLRVQENTTEQLVLFLPSLWLYALFVNP
LWAAVLGSVWVVGRVLYALGYYEASERRTPGFAVSVVATLILLGGALVGLLRRLVLP
>Mature_136_residues
GLSALDTLVWPGLVTVAALVVYYGLSLNVGRARVRYGVAPPETNGNPDFERVLRVQENTTEQLVLFLPSLWLYALFVNPL
WAAVLGSVWVVGRVLYALGYYEASERRTPGFAVSVVATLILLGGALVGLLRRLVLP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MAPEG family [H]

Homologues:

Organism=Homo sapiens, GI4505181, Length=90, Percent_Identity=43.3333333333333, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI22035629, Length=83, Percent_Identity=40.9638554216867, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001129 [H]

Pfam domain/function: PF01124 MAPEG [H]

EC number: 2.5.1.18

Molecular weight: Translated: 14928; Mature: 14797

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSALDTLVWPGLVTVAALVVYYGLSLNVGRARVRYGVAPPETNGNPDFERVLRVQENT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
TEQLVLFLPSLWLYALFVNPLWAAVLGSVWVVGRVLYALGYYEASERRTPGFAVSVVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILLGGALVGLLRRLVLP
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLSALDTLVWPGLVTVAALVVYYGLSLNVGRARVRYGVAPPETNGNPDFERVLRVQENT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHCCC
TEQLVLFLPSLWLYALFVNPLWAAVLGSVWVVGRVLYALGYYEASERRTPGFAVSVVATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ILLGGALVGLLRRLVLP
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]