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The map label for this gene is queC

Identifier: 37522606

GI number: 37522606

Start: 3232144

End: 3232848

Strand: Reverse

Name: queC

Synonym: gll3037

Alternate gene names: 37522606

Gene position: 3232848-3232144 (Counterclockwise)

Preceding gene: 37522609

Following gene: 37522605

Centisome position: 69.39

GC content: 64.11

Gene sequence:

>705_bases
ATGAAAAAAGCGCTGGTGGTCTTCTCGGGCGGTCAGGATTCGACCACCTGCGCCGCCCTCGCTTGCCGCGAGTACGACGA
GGTGCACGCGGTCACCTTCGAGTACAACCAGCGCCACGCCATCGAACTGGAGAGTGCGCGGGCGGTGGGGCAGGCTCTGG
GTCTTACCGGTCACGAATTTATCCGCCTGGGTCCGTTACTCAAGGGCACCAGTCCCCTGGTCAGCGACGCGCCCCTCGGG
CAGTACGCCTCGGCGGCGGAACTGCCTGCGGGTGTGGAGCCCACCTTCGTGCCGGGGCGCAATATTTTGTTTCTCACCCT
GGCGGCCAACCGCGCCTTTTGTCTGGGGACGGGCGACATCGTCATCGGGGTGTGCGAGGCCGATTTTGCCGGTTACTGGG
ACTGCCGACAGGTGTTTGTCGAGGCGATGGCCAGAGCCCTGGGCGAGGGCATTTACGGCGATGCGAATGCTATACGCATC
CACACGCCGCTGATGCGTCTCACCAAGGCCGAGACTGTAAAGTTGAGTGTCGAAGTGTTGGGGGAGCGCTTTGAAGAAGT
GCTTGCGCTGAGCCACACTTGTTATGCGGGGGTGCGGGGCGGCTGCGGCCGATGCCACGCCTGCATCCTGCGCGACCGGG
GCTTCCGCGAGGCGGGGGTGCCCGACCCGATCTGGAAATTTCGCAAAGAGCCCGTCTCGCTGTGA

Upstream 100 bases:

>100_bases
GACGCTCAGCGGTGGGTGGCGCGGCCGATCCCCGGGTAGGGACAATCCCGCTGGAGCTACAATCGCAGGATAAAATTTGC
CGATAAACGGGATGACGGCC

Downstream 100 bases:

>100_bases
ACGCTGCTTCGACTGTTGTCAAACCCGTGTCCGCCCAAAGCATCCCGGTGCAGGAAACCTTTGGCCCTACTATTCAGGGT
GAAGGGTACTGGGCGGGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEFIRLGPLLKGTSPLVSDAPLG
QYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRI
HTPLMRLTKAETVKLSVEVLGERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL

Sequences:

>Translated_234_residues
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEFIRLGPLLKGTSPLVSDAPLG
QYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRI
HTPLMRLTKAETVKLSVEVLGERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL
>Mature_234_residues
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEFIRLGPLLKGTSPLVSDAPLG
QYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRI
HTPLMRLTKAETVKLSVEVLGERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=226, Percent_Identity=45.575221238938, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_GLOVI (Q7NCE2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925983.1
- ProteinModelPortal:   Q7NCE2
- SMR:   Q7NCE2
- GeneID:   2601438
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:gll3037
- NMPDR:   fig|251221.1.peg.3037
- HOGENOM:   HBG553284
- OMA:   RIHTPLM
- ProtClustDB:   CLSK2462651
- BioCyc:   GVIO251221:GLL3037-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25272; Mature: 25272

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEF
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHCCCCHHH
IRLGPLLKGTSPLVSDAPLGQYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDI
HEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEECCCCEEEEEEECCCEEEEECCCE
VIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRIHTPLMRLTKAETVKLSVEVL
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHCCCHHEEEHHHHH
GERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL
HHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEF
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHHHHHCCCCHHH
IRLGPLLKGTSPLVSDAPLGQYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDI
HEECCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCEECCCCEEEEEEECCCEEEEECCCE
VIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRIHTPLMRLTKAETVKLSVEVL
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHCCCHHEEEHHHHH
GERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL
HHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292