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The map label for this gene is ykuT [H]

Identifier: 37522473

GI number: 37522473

Start: 3099191

End: 3101137

Strand: Direct

Name: ykuT [H]

Synonym: glr2904

Alternate gene names: 37522473

Gene position: 3099191-3101137 (Clockwise)

Preceding gene: 37522467

Following gene: 37522482

Centisome position: 66.52

GC content: 63.59

Gene sequence:

>1947_bases
GTGACCGATTGCAGCTTTATCGTTGAGAGTATGTCATTTCTGAATATGAACAACCGAAGTCGGGGCGGCGACGGGCGCAC
CCTCGGCGCCTGGCTGGGTGCGGTACTACTCGGCGCCTGGCTGGTCGTCGGGTGGGCGCTACCCGCACAGGCCCAACTGA
GCCTGTCCGGTTTGGGCGAACAAGCTACCGACAGCCTGCCCGAAGGGGTGCAAAGACTCGGCGAAATCGAAATTGCCCCG
GTCAAATTCGAAGGGCAGCGGATTTTTGATGTCGCATCACCGACGGTCAGAAACCGCACCTCCCCCGGCAAGTTGCTCCC
CGTCGAAGTGCGCGCCGAACTGGTCGAGGCAAGCCTCGAGCGCATCGTCGCCCCGGATGTCCGCGTCAAGGCCGTCGTGG
GCGACGACGGGCAGAAGGCCGACCCGGCAGCACCAACTTTGCCCCCCCCGGACAATGACCGGGCGCGGGACTATTTCACC
AACTATGACCCGAAATCGACTTATATCTATATTTCCAAGTTGAACGGGGCGAACGTCATCTTCGCCATCGACGACTACCA
CACCAACCCGCTCAAGATCGTCACGGTCACGGCCGCCGACGCCGACTACTACGGCCTGACCCAGGACGATCTGGCGGAGC
GCTGGCGTTCCGTACTCGAAAGCTTACTGCGCAATGCGCTGCAGGAGCGTCAGCCCGCCAGTTTCGACGGGCAGTGGCGC
TGGGCCGCCCTCGCCGTGGGTGCTGTGGCCGGGATCAGTCTGCTTATCTGGTTGCTGCAAAAGCTCATCAAAAGCCGCGA
CCGCCAGTTGGCCGAAGAACAGGCACAGCAGGCGGAGTGGGCTGCCAACCAGGCCCCTGTCGCCACCGAAAATGCCCCCG
CCGAGAACTTCGACTTTCACCGGAGGCAATTTCTGGAGGCGCTGCGCCAGCAGTTCAGCCTCCAGCGCCGCCGCAGCTTG
ATTGCTATCCTCGGGTTTTTGCTCGACTGGGCACAGGCGGTCGCCTGGGTCGTCGGGGCCACCGTGGTGCTGTATATCTT
TCCCTGGACGCGGGCCTATGCCTTTCAGGTGCTGCGCATCCCCTTCGTGCTGCTGGGGATCTGGTTTGTGGCGGGCCTCG
CCAACCGGATCGGCGACGCGGTGATCGAACGCTTCTCGAAGGTGTGGGAAGAAAACGACCTGTTCGACCTGGCGGACGTA
CAGCGCAAGTCCCTGCGCATCGCCACCACCATCCAGGCGCTCAAGGGCCTCAAGACTTTTATGATCTACCTGGTGGCCAT
CGGCTCAGCGCTCTCGTTTCTCGGAGTGCCCCTGGGCTCGGTGCTCGCCATCGGCGGTCTGGTGGCCTTCGCGATTTCTT
TTAGTCTGCAAAACCTGGTCAAAGACCTGGTCAACGGCTGCCTGATTCTCTGGGAGGACCAGTTTGCGATCGGCGATGTG
GTGGCGATCGGCGCGGTCTCAGGCGCGGTCGAGAACCTGAGCCTGCGGGTCACCCAACTGCGCAACAGCGAAGGGCGGCT
GATTACGATTCCCAACAGCGCCATCGCCCAGGTGGAGAACCTGACGCGCACCTGGTCGCGGGTGGATTTTGCCGTCGAGG
TCGCCTACGACACCGATATCCGCCGCGCCCTGGCGGTGATTGGCGACATCGCCCGCACCATGTACGACGAGCCCGAGTGG
CACGCCCAGATGCTCGAAGCGCCGCAGGTGCTGGGAGTCGACGCGCTCTCTTCGACCGGGGCGCTCATTCGGGTATGGCT
GCGCACCCAGCCGGGGCAGCAGTGGGCGGTGGGGCGCGAATTCCGCCTGCGCGTGCGCCTGGCCCTGGAGCAGAACCAAA
TCGATATCGGCACCCCCCAGCAGGCGCTGCTCTACAAGGGGACGGTACCCACGCCCAACGGCAACAGCAGCGCCGGGAGC
GGGAGCCAACCCGTCAACAAGCCATAA

Upstream 100 bases:

>100_bases
ACGGACGCGAAGAATCGCTGCAGCGATAAGATTTGCAGATAAGTTGCAGGGTTGACACAGTGGAACGAAAGCGTTCGGAC
TCCCCCATTCCCGAGAGGCA

Downstream 100 bases:

>100_bases
AAAATGGACGCCCTCGGGCCGAAAAAGCACCGACTCAAGGCAAGGTGATCTGCCCTACCTGGGTTTCCCACTGGCACTCA
CCGGCGATCGTGGTGGCCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MTDCSFIVESMSFLNMNNRSRGGDGRTLGAWLGAVLLGAWLVVGWALPAQAQLSLSGLGEQATDSLPEGVQRLGEIEIAP
VKFEGQRIFDVASPTVRNRTSPGKLLPVEVRAELVEASLERIVAPDVRVKAVVGDDGQKADPAAPTLPPPDNDRARDYFT
NYDPKSTYIYISKLNGANVIFAIDDYHTNPLKIVTVTAADADYYGLTQDDLAERWRSVLESLLRNALQERQPASFDGQWR
WAALAVGAVAGISLLIWLLQKLIKSRDRQLAEEQAQQAEWAANQAPVATENAPAENFDFHRRQFLEALRQQFSLQRRRSL
IAILGFLLDWAQAVAWVVGATVVLYIFPWTRAYAFQVLRIPFVLLGIWFVAGLANRIGDAVIERFSKVWEENDLFDLADV
QRKSLRIATTIQALKGLKTFMIYLVAIGSALSFLGVPLGSVLAIGGLVAFAISFSLQNLVKDLVNGCLILWEDQFAIGDV
VAIGAVSGAVENLSLRVTQLRNSEGRLITIPNSAIAQVENLTRTWSRVDFAVEVAYDTDIRRALAVIGDIARTMYDEPEW
HAQMLEAPQVLGVDALSSTGALIRVWLRTQPGQQWAVGREFRLRVRLALEQNQIDIGTPQQALLYKGTVPTPNGNSSAGS
GSQPVNKP

Sequences:

>Translated_648_residues
MTDCSFIVESMSFLNMNNRSRGGDGRTLGAWLGAVLLGAWLVVGWALPAQAQLSLSGLGEQATDSLPEGVQRLGEIEIAP
VKFEGQRIFDVASPTVRNRTSPGKLLPVEVRAELVEASLERIVAPDVRVKAVVGDDGQKADPAAPTLPPPDNDRARDYFT
NYDPKSTYIYISKLNGANVIFAIDDYHTNPLKIVTVTAADADYYGLTQDDLAERWRSVLESLLRNALQERQPASFDGQWR
WAALAVGAVAGISLLIWLLQKLIKSRDRQLAEEQAQQAEWAANQAPVATENAPAENFDFHRRQFLEALRQQFSLQRRRSL
IAILGFLLDWAQAVAWVVGATVVLYIFPWTRAYAFQVLRIPFVLLGIWFVAGLANRIGDAVIERFSKVWEENDLFDLADV
QRKSLRIATTIQALKGLKTFMIYLVAIGSALSFLGVPLGSVLAIGGLVAFAISFSLQNLVKDLVNGCLILWEDQFAIGDV
VAIGAVSGAVENLSLRVTQLRNSEGRLITIPNSAIAQVENLTRTWSRVDFAVEVAYDTDIRRALAVIGDIARTMYDEPEW
HAQMLEAPQVLGVDALSSTGALIRVWLRTQPGQQWAVGREFRLRVRLALEQNQIDIGTPQQALLYKGTVPTPNGNSSAGS
GSQPVNKP
>Mature_647_residues
TDCSFIVESMSFLNMNNRSRGGDGRTLGAWLGAVLLGAWLVVGWALPAQAQLSLSGLGEQATDSLPEGVQRLGEIEIAPV
KFEGQRIFDVASPTVRNRTSPGKLLPVEVRAELVEASLERIVAPDVRVKAVVGDDGQKADPAAPTLPPPDNDRARDYFTN
YDPKSTYIYISKLNGANVIFAIDDYHTNPLKIVTVTAADADYYGLTQDDLAERWRSVLESLLRNALQERQPASFDGQWRW
AALAVGAVAGISLLIWLLQKLIKSRDRQLAEEQAQQAEWAANQAPVATENAPAENFDFHRRQFLEALRQQFSLQRRRSLI
AILGFLLDWAQAVAWVVGATVVLYIFPWTRAYAFQVLRIPFVLLGIWFVAGLANRIGDAVIERFSKVWEENDLFDLADVQ
RKSLRIATTIQALKGLKTFMIYLVAIGSALSFLGVPLGSVLAIGGLVAFAISFSLQNLVKDLVNGCLILWEDQFAIGDVV
AIGAVSGAVENLSLRVTQLRNSEGRLITIPNSAIAQVENLTRTWSRVDFAVEVAYDTDIRRALAVIGDIARTMYDEPEWH
AQMLEAPQVLGVDALSSTGALIRVWLRTQPGQQWAVGREFRLRVRLALEQNQIDIGTPQQALLYKGTVPTPNGNSSAGSG
SQPVNKP

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=194, Percent_Identity=30.9278350515464, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789291, Length=222, Percent_Identity=27.4774774774775, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 71270; Mature: 71139

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDCSFIVESMSFLNMNNRSRGGDGRTLGAWLGAVLLGAWLVVGWALPAQAQLSLSGLGE
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCC
QATDSLPEGVQRLGEIEIAPVKFEGQRIFDVASPTVRNRTSPGKLLPVEVRAELVEASLE
HHHHHHHHHHHHHCCEEEEEEEECCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
RIVAPDVRVKAVVGDDGQKADPAAPTLPPPDNDRARDYFTNYDPKSTYIYISKLNGANVI
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCEEE
FAIDDYHTNPLKIVTVTAADADYYGLTQDDLAERWRSVLESLLRNALQERQPASFDGQWR
EEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
WAALAVGAVAGISLLIWLLQKLIKSRDRQLAEEQAQQAEWAANQAPVATENAPAENFDFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
RRQFLEALRQQFSLQRRRSLIAILGFLLDWAQAVAWVVGATVVLYIFPWTRAYAFQVLRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PFVLLGIWFVAGLANRIGDAVIERFSKVWEENDLFDLADVQRKSLRIATTIQALKGLKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MIYLVAIGSALSFLGVPLGSVLAIGGLVAFAISFSLQNLVKDLVNGCLILWEDQFAIGDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHH
VAIGAVSGAVENLSLRVTQLRNSEGRLITIPNSAIAQVENLTRTWSRVDFAVEVAYDTDI
HHHHHHHHHHHHHEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEEEECHHH
RRALAVIGDIARTMYDEPEWHAQMLEAPQVLGVDALSSTGALIRVWLRTQPGQQWAVGRE
HHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCC
FRLRVRLALEQNQIDIGTPQQALLYKGTVPTPNGNSSAGSGSQPVNKP
EEEEEEEEEECCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDCSFIVESMSFLNMNNRSRGGDGRTLGAWLGAVLLGAWLVVGWALPAQAQLSLSGLGE
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHCCCC
QATDSLPEGVQRLGEIEIAPVKFEGQRIFDVASPTVRNRTSPGKLLPVEVRAELVEASLE
HHHHHHHHHHHHHCCEEEEEEEECCCEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHH
RIVAPDVRVKAVVGDDGQKADPAAPTLPPPDNDRARDYFTNYDPKSTYIYISKLNGANVI
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEEEECCCCEEE
FAIDDYHTNPLKIVTVTAADADYYGLTQDDLAERWRSVLESLLRNALQERQPASFDGQWR
EEEECCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
WAALAVGAVAGISLLIWLLQKLIKSRDRQLAEEQAQQAEWAANQAPVATENAPAENFDFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
RRQFLEALRQQFSLQRRRSLIAILGFLLDWAQAVAWVVGATVVLYIFPWTRAYAFQVLRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
PFVLLGIWFVAGLANRIGDAVIERFSKVWEENDLFDLADVQRKSLRIATTIQALKGLKTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MIYLVAIGSALSFLGVPLGSVLAIGGLVAFAISFSLQNLVKDLVNGCLILWEDQFAIGDV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHH
VAIGAVSGAVENLSLRVTQLRNSEGRLITIPNSAIAQVENLTRTWSRVDFAVEVAYDTDI
HHHHHHHHHHHHHEEEEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHEEEEEEEECHHH
RRALAVIGDIARTMYDEPEWHAQMLEAPQVLGVDALSSTGALIRVWLRTQPGQQWAVGRE
HHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCHHHCCCCCEEEEEEECCCCCCCCCCCC
FRLRVRLALEQNQIDIGTPQQALLYKGTVPTPNGNSSAGSGSQPVNKP
EEEEEEEEEECCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]