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The map label for this gene is eryA [H]

Identifier: 37522398

GI number: 37522398

Start: 3011066

End: 3014665

Strand: Reverse

Name: eryA [H]

Synonym: gll2829

Alternate gene names: 37522398

Gene position: 3014665-3011066 (Counterclockwise)

Preceding gene: 37522399

Following gene: 37522397

Centisome position: 64.71

GC content: 67.61

Gene sequence:

>3600_bases
ATGGAAGCGATAGCGATTGTGGGCCTGGGCTGCCGTTTTCCCGGCGCTGCGAATCCTCTGGAGTATTGGCGGCTCTTGCG
CGACGGTGTCGATGCGATCGCCGAGGTGCCCGCCGAGCGCTGGGACGTGGATGCTTTCTACGACCCGCAAGCGATCGCCC
CCCGGACGATGAACACCCGCTGGGGCGGTTTCTTGGGCGGGGTCGATCGCTTCGACAACCAGTTTTTTGGGATCTCGGCC
CGGGAAGCCCAGTACATGGACCCCCAGCAGCGGCTGCTACTGGAGGTGGCCTACGAAGCGCTCGAAAGCGCCGGTCAACC
GCTCGAGCAGCTGGCGGGCAGCCAGACCGGCGTCTTTGTGGGCATCTGCAACAGCGATTACTACCGGCTCAATCTCAACC
AGCCCGACGACATCGACGCCTACGCGAGCACCGGCGGCATCTACTGCATCGCCGCCAACCGTCTTTCCTACCTGCTGGAT
TTGCGGGGGCCGAGCCTGGCGGTCGACACGGCCTGTTCCTCCTCGCTGGTGGCGGTGCACCTGGCCTGCCAGAGTCTGCG
CCGGGGCGAGTGCACCCTGGCGGTGGCCGCCGGTGTGCAGTTGATGCTGACCCCGGAGCTGAGCATATCGCTTGCCAAGG
CGCACATGCTCTCCCCCGACGGCCGCTGCAAAACCTTCGACAGCCGGGCGAACGGCTACGTGCGCGGCGAAGGTTGCGGT
GCAGTCATCCTCAAGCCCCTGACGCGCGCCCTGGGCGACGGTGACCCGATCCTCGCGATCATCCGCGGCACCGCCACCAA
TCAGGACGGGCGCAGCAACGGCCTCACCGCCCCCAACGGTTACGCCCAGCAGGCCGTCATCCGCGCAGCCCTGGCCGACG
CCGGCATTCCCGCAGGCGAGATCGACTATGTCGAGGCCCACGGCACCGGTACCCCCTTAGGCGATCCGATCGAAGCGCTC
GCCCTCGGCGCGGTGCTCGCCGAGGGCCGCCCCGCGGACCGGCCCTGCCGCGTCGGCTCGGCCAAGACCAACATCGGCCA
CCTCGAAGCGGCGGCGGGTATCGCCGGTCTCATCAAGGTGGTGCTGGCCCTCCAGCACCGGCTCCTCCCGCCCAATTTGC
ACTTCGAAGCGGCCAACCCGCATATCCCCTTCGATCGTCTGCCCCTCAGGGTGCAGGAACGCCTGGAACCCTGGCCGCGG
CGGGAGGGACCGGCCAGGGCGGGGGTGAGTTCCTTCGGTTTCGGCGGCACCAACGCCCACATCGTCCTGCAGGAGGCGCC
GGTGGGCGGCTTCGAAAGCTTGCCCGCGGACGACAGTCCCCAGCTGTTGCCCCTGTCCGCCCGCAGCGCCGAGGCCCTGC
GGGATCTGGCGGACACTTTGCGCAGGCGGTTGGTGTCCGAACCGGAGACCGACGCCCTGGCGCAATGGTGCTACAGCGCG
GGGGTCCGGCGCACCCACCACAGCCATCGCCTCTGCCTGGTCGCCCGCTCGCAGGCGGAACTGGCCGGGCACCTCGAAAC
CTGGCTGCAGGGCGTTACCCCCCCCGGCGGCAGCCAGGGGCGCAAGCTGCCCAGCCGTTCGCTGAAGGTGGCCTTTGTCT
TCACGGGCCAGGGGCCGCAGTGGTGGGCGATGGGGCGGCAACTCTGGCAGCGCGAAGCGGTCTTTCGGCAAGTTTTCGGC
GAGTGCGACCGCCTGATGGGCCGCTACGCCGACTGGTCGCTTGTGCAGGAACTGCTCGCCGAGAAGACCGAGTCGCGCCT
GCAGGAAACCGAGATCGCCCAACCGGTCCTGTTCGCCCTGCAGGTGGCACTGGCGGCCCTCTGGCGTTCGTGGGGCGTCA
CCCCCGATGCGGTGGTCGGCCACAGCGTCGGTGAAGTGGCCGCCGCCTACGTGGCGGGCGCTTTGAATCTACCGGACGCA
TTGCAGTTGGTTTTTCGCCGGGCGCAACTGATGCAGCGCGCCACCGGGGCGGGCCGGATGGCCGCCGTCTGGCTGGGCCG
CGCTGAGGTGGAACTGCTCATCGCCGCCTACGCGGGCCGGCTCTCCGTCGCCGCGCTCAACAGCCCCACCACGACGGTCC
TCTCCGGCGAGGCCGACGCCCTGGCGGCCGTCCTCGAACAGCTTCAGCAACGGGGCGTGACCACCAAGATGCTGCCGGTC
AACTACGCCTTCCACTGCCCCCAAATGGAACCGATGCGCCCGGAACTGATCGGATACCTCCACGATCTCAAGCCGCGAGC
CGGGCAAATTCCCTTCTATTCGACGGTCACCGGCCAAATCCACCCTTGCAGCGACCTCGACGCCGAATACTGGGGCCGCA
ACCTGCGCGAAGCCGTCCAGTTTGCCGATGCGGTCGACGCGATGATCCAGAGCGGCCACCATATCTTTGTCGAAATCGGC
CCGCACCCGGCCCTGGCCTCCGCCCTGGCCGAATGCCTGGAGCGCCGGGGGAAGCAGGGCGCCTGCCTGCCTTCGCTGCG
GCGCTACGAGGATGAGCGGGCCACGATGCTCGCAAGCCTCGGACAACTGTATACCCTGGGCTGCCGCGTGGATTGGCGGC
TTTTATACCCGCAGGGACCATTGCCGTTCGTCCCCCTACCTGCGTACCCATGGCAATGGCAGCGCTTCTGGCTTGAAAGC
GCGAACGGTGCGCAGGCGAGCAACGGCCATGCTGCCAAGCGGTTCGCCGCAGTGGGCAACGGCCATCTGCCTGTCGGTCC
GCCGCAGGCGACCGCACCCGCAGAAGTCTCACCCCGCGACGCGCTGCTTGCCGCTTCGCCCGCTGAGCGCCTGGTGCACC
TGGGGGGTTATCTGCGCGAGAAGCTGGCCGCGGTGCTGCGCCAGCCGATGAACGCCGTGGATCCGCAGCAGCCGCTCACC
CAGTTGGGTCTCGATTCGTTGATGGCGGTGGAACTGCGGGCGCGCGTGCTGGAGGACTTTCAGATCAATATCCCGATCAA
CCTGTTCTTTAACAACACGGGCCTCGGGCACTTGGCGGAGTTTTTGGCGGAGCAGACCCCGGCCGCCGAAGTCCCCGCCG
CCGCCGTCCTCCCGCTGTTGGATCCGGCCGTGGGCATGCCTTGGTTTCGGGCCTGGCAGCAGGAGTTCGATCCGCGGCGC
ATCGAGCGCATCGATCGGCAGTTGGTCCACAAGGACTACGACCACAACGTGCTGTTGGCGCGCTTGAGCCGGGCGGACGA
AAACACGGTGCTCGCCGAGATGGTTCAGGATCCGGCGCACCCGTTCTTCTACGAACACCCCAAAGACCACGTTCCGGGGC
TCTATCTCGTTGAAGCCGCCCGCCAACTGGTGACGGCGCTTTCGCACGTCTACCACGGCGTGGCGATGGGCAAAGCCTTC
ATCCTCGACGAGATCCAGGCCCGCTTCCTGCGGCTTGCCGAGACGGACGCGCCCGTGTTCTTGATTGCCCGCAGCCGCGC
TCCCGTCTACTCCCGGGGTGAGCTGCTGCAGATGCATAACGATCTGTGCCTGCTGCAAAACGAGGCGGTGGTGGCTGAGA
TGAGCTGCCTGTTTCGGGTCTTCGACCCGGTGGGCTACGACCACCTGCGCAGCCGCAAAAGCCAGGCCGTGCCCGGCTAG

Upstream 100 bases:

>100_bases
CGCTGTTCTGGAACCACCCGACCCTGGTGTCCTTCAGCCACCGGATCGCCGAGGAAGCTGCCGGCCCGGCCCACCCGAAG
CCTGATCAAGGAGAGCCGCG

Downstream 100 bases:

>100_bases
CCGGACTGCCATCGCGTTACGACGAGGAACAACAATGAACATTCAAGGGATATTTCTCGATTTCGACGGGGTGATCTCGG
GCAACTCCAACGAACTGATG

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase II; DEBS 2; ORF 2 [H]

Number of amino acids: Translated: 1199; Mature: 1199

Protein sequence:

>1199_residues
MEAIAIVGLGCRFPGAANPLEYWRLLRDGVDAIAEVPAERWDVDAFYDPQAIAPRTMNTRWGGFLGGVDRFDNQFFGISA
REAQYMDPQQRLLLEVAYEALESAGQPLEQLAGSQTGVFVGICNSDYYRLNLNQPDDIDAYASTGGIYCIAANRLSYLLD
LRGPSLAVDTACSSSLVAVHLACQSLRRGECTLAVAAGVQLMLTPELSISLAKAHMLSPDGRCKTFDSRANGYVRGEGCG
AVILKPLTRALGDGDPILAIIRGTATNQDGRSNGLTAPNGYAQQAVIRAALADAGIPAGEIDYVEAHGTGTPLGDPIEAL
ALGAVLAEGRPADRPCRVGSAKTNIGHLEAAAGIAGLIKVVLALQHRLLPPNLHFEAANPHIPFDRLPLRVQERLEPWPR
REGPARAGVSSFGFGGTNAHIVLQEAPVGGFESLPADDSPQLLPLSARSAEALRDLADTLRRRLVSEPETDALAQWCYSA
GVRRTHHSHRLCLVARSQAELAGHLETWLQGVTPPGGSQGRKLPSRSLKVAFVFTGQGPQWWAMGRQLWQREAVFRQVFG
ECDRLMGRYADWSLVQELLAEKTESRLQETEIAQPVLFALQVALAALWRSWGVTPDAVVGHSVGEVAAAYVAGALNLPDA
LQLVFRRAQLMQRATGAGRMAAVWLGRAEVELLIAAYAGRLSVAALNSPTTTVLSGEADALAAVLEQLQQRGVTTKMLPV
NYAFHCPQMEPMRPELIGYLHDLKPRAGQIPFYSTVTGQIHPCSDLDAEYWGRNLREAVQFADAVDAMIQSGHHIFVEIG
PHPALASALAECLERRGKQGACLPSLRRYEDERATMLASLGQLYTLGCRVDWRLLYPQGPLPFVPLPAYPWQWQRFWLES
ANGAQASNGHAAKRFAAVGNGHLPVGPPQATAPAEVSPRDALLAASPAERLVHLGGYLREKLAAVLRQPMNAVDPQQPLT
QLGLDSLMAVELRARVLEDFQINIPINLFFNNTGLGHLAEFLAEQTPAAEVPAAAVLPLLDPAVGMPWFRAWQQEFDPRR
IERIDRQLVHKDYDHNVLLARLSRADENTVLAEMVQDPAHPFFYEHPKDHVPGLYLVEAARQLVTALSHVYHGVAMGKAF
ILDEIQARFLRLAETDAPVFLIARSRAPVYSRGELLQMHNDLCLLQNEAVVAEMSCLFRVFDPVGYDHLRSRKSQAVPG

Sequences:

>Translated_1199_residues
MEAIAIVGLGCRFPGAANPLEYWRLLRDGVDAIAEVPAERWDVDAFYDPQAIAPRTMNTRWGGFLGGVDRFDNQFFGISA
REAQYMDPQQRLLLEVAYEALESAGQPLEQLAGSQTGVFVGICNSDYYRLNLNQPDDIDAYASTGGIYCIAANRLSYLLD
LRGPSLAVDTACSSSLVAVHLACQSLRRGECTLAVAAGVQLMLTPELSISLAKAHMLSPDGRCKTFDSRANGYVRGEGCG
AVILKPLTRALGDGDPILAIIRGTATNQDGRSNGLTAPNGYAQQAVIRAALADAGIPAGEIDYVEAHGTGTPLGDPIEAL
ALGAVLAEGRPADRPCRVGSAKTNIGHLEAAAGIAGLIKVVLALQHRLLPPNLHFEAANPHIPFDRLPLRVQERLEPWPR
REGPARAGVSSFGFGGTNAHIVLQEAPVGGFESLPADDSPQLLPLSARSAEALRDLADTLRRRLVSEPETDALAQWCYSA
GVRRTHHSHRLCLVARSQAELAGHLETWLQGVTPPGGSQGRKLPSRSLKVAFVFTGQGPQWWAMGRQLWQREAVFRQVFG
ECDRLMGRYADWSLVQELLAEKTESRLQETEIAQPVLFALQVALAALWRSWGVTPDAVVGHSVGEVAAAYVAGALNLPDA
LQLVFRRAQLMQRATGAGRMAAVWLGRAEVELLIAAYAGRLSVAALNSPTTTVLSGEADALAAVLEQLQQRGVTTKMLPV
NYAFHCPQMEPMRPELIGYLHDLKPRAGQIPFYSTVTGQIHPCSDLDAEYWGRNLREAVQFADAVDAMIQSGHHIFVEIG
PHPALASALAECLERRGKQGACLPSLRRYEDERATMLASLGQLYTLGCRVDWRLLYPQGPLPFVPLPAYPWQWQRFWLES
ANGAQASNGHAAKRFAAVGNGHLPVGPPQATAPAEVSPRDALLAASPAERLVHLGGYLREKLAAVLRQPMNAVDPQQPLT
QLGLDSLMAVELRARVLEDFQINIPINLFFNNTGLGHLAEFLAEQTPAAEVPAAAVLPLLDPAVGMPWFRAWQQEFDPRR
IERIDRQLVHKDYDHNVLLARLSRADENTVLAEMVQDPAHPFFYEHPKDHVPGLYLVEAARQLVTALSHVYHGVAMGKAF
ILDEIQARFLRLAETDAPVFLIARSRAPVYSRGELLQMHNDLCLLQNEAVVAEMSCLFRVFDPVGYDHLRSRKSQAVPG
>Mature_1199_residues
MEAIAIVGLGCRFPGAANPLEYWRLLRDGVDAIAEVPAERWDVDAFYDPQAIAPRTMNTRWGGFLGGVDRFDNQFFGISA
REAQYMDPQQRLLLEVAYEALESAGQPLEQLAGSQTGVFVGICNSDYYRLNLNQPDDIDAYASTGGIYCIAANRLSYLLD
LRGPSLAVDTACSSSLVAVHLACQSLRRGECTLAVAAGVQLMLTPELSISLAKAHMLSPDGRCKTFDSRANGYVRGEGCG
AVILKPLTRALGDGDPILAIIRGTATNQDGRSNGLTAPNGYAQQAVIRAALADAGIPAGEIDYVEAHGTGTPLGDPIEAL
ALGAVLAEGRPADRPCRVGSAKTNIGHLEAAAGIAGLIKVVLALQHRLLPPNLHFEAANPHIPFDRLPLRVQERLEPWPR
REGPARAGVSSFGFGGTNAHIVLQEAPVGGFESLPADDSPQLLPLSARSAEALRDLADTLRRRLVSEPETDALAQWCYSA
GVRRTHHSHRLCLVARSQAELAGHLETWLQGVTPPGGSQGRKLPSRSLKVAFVFTGQGPQWWAMGRQLWQREAVFRQVFG
ECDRLMGRYADWSLVQELLAEKTESRLQETEIAQPVLFALQVALAALWRSWGVTPDAVVGHSVGEVAAAYVAGALNLPDA
LQLVFRRAQLMQRATGAGRMAAVWLGRAEVELLIAAYAGRLSVAALNSPTTTVLSGEADALAAVLEQLQQRGVTTKMLPV
NYAFHCPQMEPMRPELIGYLHDLKPRAGQIPFYSTVTGQIHPCSDLDAEYWGRNLREAVQFADAVDAMIQSGHHIFVEIG
PHPALASALAECLERRGKQGACLPSLRRYEDERATMLASLGQLYTLGCRVDWRLLYPQGPLPFVPLPAYPWQWQRFWLES
ANGAQASNGHAAKRFAAVGNGHLPVGPPQATAPAEVSPRDALLAASPAERLVHLGGYLREKLAAVLRQPMNAVDPQQPLT
QLGLDSLMAVELRARVLEDFQINIPINLFFNNTGLGHLAEFLAEQTPAAEVPAAAVLPLLDPAVGMPWFRAWQQEFDPRR
IERIDRQLVHKDYDHNVLLARLSRADENTVLAEMVQDPAHPFFYEHPKDHVPGLYLVEAARQLVTALSHVYHGVAMGKAF
ILDEIQARFLRLAETDAPVFLIARSRAPVYSRGELLQMHNDLCLLQNEAVVAEMSCLFRVFDPVGYDHLRSRKSQAVPG

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=896, Percent_Identity=33.7053571428571, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI8923559, Length=434, Percent_Identity=26.4976958525346, Blast_Score=120, Evalue=8e-27,
Organism=Homo sapiens, GI310129082, Length=111, Percent_Identity=43.2432432432432, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI310109937, Length=111, Percent_Identity=43.2432432432432, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI239744023, Length=111, Percent_Identity=43.2432432432432, Blast_Score=94, Evalue=7e-19,
Organism=Homo sapiens, GI223972627, Length=156, Percent_Identity=35.8974358974359, Blast_Score=81, Evalue=7e-15,
Organism=Escherichia coli, GI1787337, Length=436, Percent_Identity=26.605504587156, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1787334, Length=285, Percent_Identity=29.8245614035088, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788663, Length=272, Percent_Identity=26.8382352941176, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=910, Percent_Identity=29.8901098901099, Blast_Score=357, Evalue=3e-98,
Organism=Caenorhabditis elegans, GI17550940, Length=951, Percent_Identity=27.1293375394322, Blast_Score=259, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI71983541, Length=362, Percent_Identity=27.3480662983425, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71983535, Length=273, Percent_Identity=30.03663003663, Blast_Score=98, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320904, Length=457, Percent_Identity=26.4770240700219, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24581345, Length=879, Percent_Identity=31.3993174061433, Blast_Score=360, Evalue=5e-99,
Organism=Drosophila melanogaster, GI221330659, Length=912, Percent_Identity=29.9342105263158, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI19920632, Length=912, Percent_Identity=29.9342105263158, Blast_Score=357, Evalue=2e-98,
Organism=Drosophila melanogaster, GI24644341, Length=436, Percent_Identity=28.2110091743119, Blast_Score=120, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR015357
- InterPro:   IPR011032
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020807
- InterPro:   IPR020843
- InterPro:   IPR020806
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF08240 ADH_N; PF00106 adh_short; PF00107 ADH_zinc_N; PF08990 Docking; PF09277 Erythro-docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 130729; Mature: 130729

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAIAIVGLGCRFPGAANPLEYWRLLRDGVDAIAEVPAERWDVDAFYDPQAIAPRTMNTR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCC
WGGFLGGVDRFDNQFFGISAREAQYMDPQQRLLLEVAYEALESAGQPLEQLAGSQTGVFV
CCCHHCCHHHHCCCEECCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEE
GICNSDYYRLNLNQPDDIDAYASTGGIYCIAANRLSYLLDLRGPSLAVDTACSSSLVAVH
EEECCCEEEEECCCCCCCCHHHCCCCEEEEECCCHHHHHCCCCCCEEEHHHCCCHHHHHH
LACQSLRRGECTLAVAAGVQLMLTPELSISLAKAHMLSPDGRCKTFDSRANGYVRGEGCG
HHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCC
AVILKPLTRALGDGDPILAIIRGTATNQDGRSNGLTAPNGYAQQAVIRAALADAGIPAGE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
IDYVEAHGTGTPLGDPIEALALGAVLAEGRPADRPCRVGSAKTNIGHLEAAAGIAGLIKV
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLALQHRLLPPNLHFEAANPHIPFDRLPLRVQERLEPWPRREGPARAGVSSFGFGGTNAH
HHHHHHHCCCCCCEEECCCCCCCHHCCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEE
IVLQEAPVGGFESLPADDSPQLLPLSARSAEALRDLADTLRRRLVSEPETDALAQWCYSA
EEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GVRRTHHSHRLCLVARSQAELAGHLETWLQGVTPPGGSQGRKLPSRSLKVAFVFTGQGPQ
CHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCH
WWAMGRQLWQREAVFRQVFGECDRLMGRYADWSLVQELLAEKTESRLQETEIAQPVLFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVALAALWRSWGVTPDAVVGHSVGEVAAAYVAGALNLPDALQLVFRRAQLMQRATGAGRM
HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCE
AAVWLGRAEVELLIAAYAGRLSVAALNSPTTTVLSGEADALAAVLEQLQQRGVTTKMLPV
EEEEECHHHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEEC
NYAFHCPQMEPMRPELIGYLHDLKPRAGQIPFYSTVTGQIHPCSDLDAEYWGRNLREAVQ
CEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHCHHHHHHHH
FADAVDAMIQSGHHIFVEIGPHPALASALAECLERRGKQGACLPSLRRYEDERATMLASL
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GQLYTLGCRVDWRLLYPQGPLPFVPLPAYPWQWQRFWLESANGAQASNGHAAKRFAAVGN
HHHEEECCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
GHLPVGPPQATAPAEVSPRDALLAASPAERLVHLGGYLREKLAAVLRQPMNAVDPQQPLT
CCCCCCCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QLGLDSLMAVELRARVLEDFQINIPINLFFNNTGLGHLAEFLAEQTPAAEVPAAAVLPLL
HHCHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
DPAVGMPWFRAWQQEFDPRRIERIDRQLVHKDYDHNVLLARLSRADENTVLAEMVQDPAH
CHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHCCCC
PFFYEHPKDHVPGLYLVEAARQLVTALSHVYHGVAMGKAFILDEIQARFLRLAETDAPVF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LIARSRAPVYSRGELLQMHNDLCLLQNEAVVAEMSCLFRVFDPVGYDHLRSRKSQAVPG
EEECCCCCCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MEAIAIVGLGCRFPGAANPLEYWRLLRDGVDAIAEVPAERWDVDAFYDPQAIAPRTMNTR
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCC
WGGFLGGVDRFDNQFFGISAREAQYMDPQQRLLLEVAYEALESAGQPLEQLAGSQTGVFV
CCCHHCCHHHHCCCEECCCCCCCHHCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEE
GICNSDYYRLNLNQPDDIDAYASTGGIYCIAANRLSYLLDLRGPSLAVDTACSSSLVAVH
EEECCCEEEEECCCCCCCCHHHCCCCEEEEECCCHHHHHCCCCCCEEEHHHCCCHHHHHH
LACQSLRRGECTLAVAAGVQLMLTPELSISLAKAHMLSPDGRCKTFDSRANGYVRGEGCG
HHHHHHCCCCEEEEEECCEEEEECCCCHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCC
AVILKPLTRALGDGDPILAIIRGTATNQDGRSNGLTAPNGYAQQAVIRAALADAGIPAGE
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
IDYVEAHGTGTPLGDPIEALALGAVLAEGRPADRPCRVGSAKTNIGHLEAAAGIAGLIKV
EEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
VLALQHRLLPPNLHFEAANPHIPFDRLPLRVQERLEPWPRREGPARAGVSSFGFGGTNAH
HHHHHHHCCCCCCEEECCCCCCCHHCCCHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCEE
IVLQEAPVGGFESLPADDSPQLLPLSARSAEALRDLADTLRRRLVSEPETDALAQWCYSA
EEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GVRRTHHSHRLCLVARSQAELAGHLETWLQGVTPPGGSQGRKLPSRSLKVAFVFTGQGPQ
CHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCH
WWAMGRQLWQREAVFRQVFGECDRLMGRYADWSLVQELLAEKTESRLQETEIAQPVLFAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVALAALWRSWGVTPDAVVGHSVGEVAAAYVAGALNLPDALQLVFRRAQLMQRATGAGRM
HHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCE
AAVWLGRAEVELLIAAYAGRLSVAALNSPTTTVLSGEADALAAVLEQLQQRGVTTKMLPV
EEEEECHHHHHHHHHHHHCCEEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCEEEEEEC
NYAFHCPQMEPMRPELIGYLHDLKPRAGQIPFYSTVTGQIHPCSDLDAEYWGRNLREAVQ
CEEEECCCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHCHHHHHHHH
FADAVDAMIQSGHHIFVEIGPHPALASALAECLERRGKQGACLPSLRRYEDERATMLASL
HHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
GQLYTLGCRVDWRLLYPQGPLPFVPLPAYPWQWQRFWLESANGAQASNGHAAKRFAAVGN
HHHEEECCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
GHLPVGPPQATAPAEVSPRDALLAASPAERLVHLGGYLREKLAAVLRQPMNAVDPQQPLT
CCCCCCCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
QLGLDSLMAVELRARVLEDFQINIPINLFFNNTGLGHLAEFLAEQTPAAEVPAAAVLPLL
HHCHHHHHHHHHHHHHHHCEEEEEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
DPAVGMPWFRAWQQEFDPRRIERIDRQLVHKDYDHNVLLARLSRADENTVLAEMVQDPAH
CHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHCCCC
PFFYEHPKDHVPGLYLVEAARQLVTALSHVYHGVAMGKAFILDEIQARFLRLAETDAPVF
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
LIARSRAPVYSRGELLQMHNDLCLLQNEAVVAEMSCLFRVFDPVGYDHLRSRKSQAVPG
EEECCCCCCCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2024119; 1740151 [H]