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The map label for this gene is choB [H]

Identifier: 37522393

GI number: 37522393

Start: 3005543

End: 3007081

Strand: Reverse

Name: choB [H]

Synonym: gll2824

Alternate gene names: 37522393

Gene position: 3007081-3005543 (Counterclockwise)

Preceding gene: 37522394

Following gene: 37522392

Centisome position: 64.54

GC content: 65.69

Gene sequence:

>1539_bases
ATGACTGATATGCGCTTGAAGCGTCGCCGTCTGCTGCAGGCCGCTCTGCTGGCGTCAGCCGGCGCGCGGATCGAGCCGGC
CCGCGGCGCCGATGCGGCGCTCGACGCCGTGGTAATTGGAAGCGGGTTCGGCGGGGCAGTAGCAGCTCTGCGTTTGGGTC
AGGCCGGTTTTAGCACCCTGGTGCTGGAGCGCGGCCGCCGCTGGCCGATTGCGCCGAGCCAAGATACGTTTTGCACCTAC
AGCAAGCCGGACGGACGGGCTGCCTGGCTTAGCCCGACAACCCTGCTGTTTGAGCCGGTGGCGATCGATATCTACACGGG
CATCCTGGATGTCAAGGTCGGCAACGGCATCGCCGCTTTCCGCGGGGCCGGCGTGGGCGGCGGATCGCTCGTCTACAACG
CCGTGCTCTACCAACCCCGCCGCGAACTGTTCTATCAAGCCTTTCCAGGGTCCATCGACTACGACGAACTTGATCGGGTC
TACTACCCGCGGGTGCGCTCTCAGCTCAAGCCCGCGCCTGTGCCCGCGGACATCCTGGGGACACCCTACTACGAGGGCAC
CCGCGTCTTCTTGCAGCAGGCGGCCCGCGCCGGTCTCAGCCATCGCCTTCTCGATATTGCCGTCGATTGGGACATCGTGC
GCCAGGAGATCCAAGGCCGTCGGGCGGCTTCTACGATCGTGGGCGATGTTTTCTACGGCATCAACAGCGGCGCCAAAAAC
AGTCTTGACCGCAACTACCTGGCCCAGGCGGAAGCGACGGGCAATGTCGAAATTCTCCCCTTGCATGTGGTGACGGCCAT
TGCCGAAGCGGGCCGGGGCGGCTTTCAAATCCAGTGCAACCAGATCGACGAGGCCGGGCAGGTACAGGTCCGCCGCACGT
TTCGCTGCCGCTATTTGTTTTTGGCGGCGGGCTCGATCGGTACGACCGAACTGCTGCTGCGGGCAAAAGCGACAGGAACC
CTACCCCGTTTGAACCAGGCGGTGGGCCGCTTCTGGGGAACCAACGGCGACACGCTGGGCACCCGCCAGGGCAGCACGCC
GACCAATCCCACCCAAGGGGGACCGGCGACAGCAGTCATCGAACATCTCGACAACCCGCTCGCCCCGACTGTGCTTGTGC
ACACGCCCTTCTACAACAGCCCGCAAGGAGCCCTGGTCCATACAGGGCTCCAGCCGGTCAAGCCGGAAGGCTCGCTCAGC
TACGACGCCGCCACGGACACTGTCGCGCTCAACTGGCCCACCGCCACGGCCACCGCCCGACGCAACGCGCAGGCGGTGCA
ACTCACCTACGACATCCTCGATGCGGCCAACGAGACGGCGACAACGGCCCCGGCGGACACCGGGATCACTGCCCATCCCC
TCGGTGGCGCGGCCATGGACAAAGTATGCGACACCGATGGTCGCGTCCGAGGCTACGAGGGACTCTACGTGGTGGACGGG
GCGCTTATCCCCGGCTCGACCGCCTGCACAAATCCGGCGCTCACCATCGCCGCCCTGGCGGAACGGTGCCTGGAGCGGTT
TCTCGATCGGCGCCTTTGA

Upstream 100 bases:

>100_bases
GACGAGGCCCACCGCCGCATCGAGCAGCGGGCCACCACCGGCAAGCTCATCCTCAAAATTGGCCGGTAGCCCCCTTTGAA
GCACCCTACCGAGAGTACCG

Downstream 100 bases:

>100_bases
GCCTGGGCGTACTGCAATTTCACCGATTTGGACAACACCAATGCTGAACACACGCTCTACTGTCGGCTGGTGCAGCCGGC
TCGGGCTGACGGCGCTGCTG

Product: cholesterol oxidase

Products: NA

Alternate protein names: CHOD [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MTDMRLKRRRLLQAALLASAGARIEPARGADAALDAVVIGSGFGGAVAALRLGQAGFSTLVLERGRRWPIAPSQDTFCTY
SKPDGRAAWLSPTTLLFEPVAIDIYTGILDVKVGNGIAAFRGAGVGGGSLVYNAVLYQPRRELFYQAFPGSIDYDELDRV
YYPRVRSQLKPAPVPADILGTPYYEGTRVFLQQAARAGLSHRLLDIAVDWDIVRQEIQGRRAASTIVGDVFYGINSGAKN
SLDRNYLAQAEATGNVEILPLHVVTAIAEAGRGGFQIQCNQIDEAGQVQVRRTFRCRYLFLAAGSIGTTELLLRAKATGT
LPRLNQAVGRFWGTNGDTLGTRQGSTPTNPTQGGPATAVIEHLDNPLAPTVLVHTPFYNSPQGALVHTGLQPVKPEGSLS
YDAATDTVALNWPTATATARRNAQAVQLTYDILDAANETATTAPADTGITAHPLGGAAMDKVCDTDGRVRGYEGLYVVDG
ALIPGSTACTNPALTIAALAERCLERFLDRRL

Sequences:

>Translated_512_residues
MTDMRLKRRRLLQAALLASAGARIEPARGADAALDAVVIGSGFGGAVAALRLGQAGFSTLVLERGRRWPIAPSQDTFCTY
SKPDGRAAWLSPTTLLFEPVAIDIYTGILDVKVGNGIAAFRGAGVGGGSLVYNAVLYQPRRELFYQAFPGSIDYDELDRV
YYPRVRSQLKPAPVPADILGTPYYEGTRVFLQQAARAGLSHRLLDIAVDWDIVRQEIQGRRAASTIVGDVFYGINSGAKN
SLDRNYLAQAEATGNVEILPLHVVTAIAEAGRGGFQIQCNQIDEAGQVQVRRTFRCRYLFLAAGSIGTTELLLRAKATGT
LPRLNQAVGRFWGTNGDTLGTRQGSTPTNPTQGGPATAVIEHLDNPLAPTVLVHTPFYNSPQGALVHTGLQPVKPEGSLS
YDAATDTVALNWPTATATARRNAQAVQLTYDILDAANETATTAPADTGITAHPLGGAAMDKVCDTDGRVRGYEGLYVVDG
ALIPGSTACTNPALTIAALAERCLERFLDRRL
>Mature_511_residues
TDMRLKRRRLLQAALLASAGARIEPARGADAALDAVVIGSGFGGAVAALRLGQAGFSTLVLERGRRWPIAPSQDTFCTYS
KPDGRAAWLSPTTLLFEPVAIDIYTGILDVKVGNGIAAFRGAGVGGGSLVYNAVLYQPRRELFYQAFPGSIDYDELDRVY
YPRVRSQLKPAPVPADILGTPYYEGTRVFLQQAARAGLSHRLLDIAVDWDIVRQEIQGRRAASTIVGDVFYGINSGAKNS
LDRNYLAQAEATGNVEILPLHVVTAIAEAGRGGFQIQCNQIDEAGQVQVRRTFRCRYLFLAAGSIGTTELLLRAKATGTL
PRLNQAVGRFWGTNGDTLGTRQGSTPTNPTQGGPATAVIEHLDNPLAPTVLVHTPFYNSPQGALVHTGLQPVKPEGSLSY
DAATDTVALNWPTATATARRNAQAVQLTYDILDAANETATTAPADTGITAHPLGGAAMDKVCDTDGRVRGYEGLYVVDGA
LIPGSTACTNPALTIAALAERCLERFLDRRL

Specific function: Unknown

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.3.6 [H]

Molecular weight: Translated: 54636; Mature: 54504

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDMRLKRRRLLQAALLASAGARIEPARGADAALDAVVIGSGFGGAVAALRLGQAGFSTL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHCCCCHHHH
VLERGRRWPIAPSQDTFCTYSKPDGRAAWLSPTTLLFEPVAIDIYTGILDVKVGNGIAAF
HHHCCCCCCCCCCCCCEEEECCCCCCEEEECCCEEEECCEEEEEEECEEEEEECCCEEEC
RGAGVGGGSLVYNAVLYQPRRELFYQAFPGSIDYDELDRVYYPRVRSQLKPAPVPADILG
CCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCC
TPYYEGTRVFLQQAARAGLSHRLLDIAVDWDIVRQEIQGRRAASTIVGDVFYGINSGAKN
CCCCCHHHHHHHHHHHCCCHHEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
SLDRNYLAQAEATGNVEILPLHVVTAIAEAGRGGFQIQCNQIDEAGQVQVRRTFRCRYLF
CCCHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHEEEEEEE
LAAGSIGTTELLLRAKATGTLPRLNQAVGRFWGTNGDTLGTRQGSTPTNPTQGGPATAVI
EECCCCCHHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
EHLDNPLAPTVLVHTPFYNSPQGALVHTGLQPVKPEGSLSYDAATDTVALNWPTATATAR
HHCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCHHHHH
RNAQAVQLTYDILDAANETATTAPADTGITAHPLGGAAMDKVCDTDGRVRGYEGLYVVDG
CCCEEEEEEHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHCCCCCEECCCCEEEEEC
ALIPGSTACTNPALTIAALAERCLERFLDRRL
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDMRLKRRRLLQAALLASAGARIEPARGADAALDAVVIGSGFGGAVAALRLGQAGFSTL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEEEECCCCHHHHHHHHCCCCHHHH
VLERGRRWPIAPSQDTFCTYSKPDGRAAWLSPTTLLFEPVAIDIYTGILDVKVGNGIAAF
HHHCCCCCCCCCCCCCEEEECCCCCCEEEECCCEEEECCEEEEEEECEEEEEECCCEEEC
RGAGVGGGSLVYNAVLYQPRRELFYQAFPGSIDYDELDRVYYPRVRSQLKPAPVPADILG
CCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCC
TPYYEGTRVFLQQAARAGLSHRLLDIAVDWDIVRQEIQGRRAASTIVGDVFYGINSGAKN
CCCCCHHHHHHHHHHHCCCHHEEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
SLDRNYLAQAEATGNVEILPLHVVTAIAEAGRGGFQIQCNQIDEAGQVQVRRTFRCRYLF
CCCHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEHEEEEEEE
LAAGSIGTTELLLRAKATGTLPRLNQAVGRFWGTNGDTLGTRQGSTPTNPTQGGPATAVI
EECCCCCHHHHHEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
EHLDNPLAPTVLVHTPFYNSPQGALVHTGLQPVKPEGSLSYDAATDTVALNWPTATATAR
HHCCCCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCHHHHH
RNAQAVQLTYDILDAANETATTAPADTGITAHPLGGAAMDKVCDTDGRVRGYEGLYVVDG
CCCEEEEEEHHHHHCCCCCCCCCCCCCCCEECCCCCHHHHHHHCCCCCEECCCCEEEEEC
ALIPGSTACTNPALTIAALAERCLERFLDRRL
EECCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1879703; 2271066; 2051487 [H]