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The map label for this gene is yraA [H]

Identifier: 37522382

GI number: 37522382

Start: 2992921

End: 2993472

Strand: Direct

Name: yraA [H]

Synonym: glr2813

Alternate gene names: 37522382

Gene position: 2992921-2993472 (Clockwise)

Preceding gene: 37522381

Following gene: 37522383

Centisome position: 64.24

GC content: 60.51

Gene sequence:

>552_bases
ATGGCCGATCTGTCGCGCCTGCGGGTGGCGGTACTCGCTACCGACGGCTTTGAAGAAACGGAACTGACCGAGCCGATGCG
TGCCCTCCAACAAGCGGGTGCCCATGTCGAAATTATTGCGCCCGCAGCGGGAGAGATCCAGGCGTTTCGCCACCACGACA
AGAGCGTGCGTGTTGCTGTCGACCGGACGCTCAACGAAGCGCAACCGAACCAATACGACGCTCTGGTGCTGCCTGGAGGA
ACATTCAACGCCGATGCACTGCGTGTCGATCCCAAGGTGCAGGCTTTTGTGCGCAATATGCACCAGTCCGGCAAACCCAT
CGCCGCCATTTGCCATGCCCCGTGGATCTTGATCTCGACGGGGCTGGTGAAAGGGCGGACGCTCACCAGCTATCACACAC
TCCAAGATGATGTCCGCAATGCTGGGGGGCGATGGCAAGATCGCGAGGTGATCGTCGAGGGCAACTGGGTGACCAGCCGC
AAACCGGACGATCTACCAGCATTCAACCGGGAACTACTCAACCAACTGAGTGCGCTGCCCGGTCGGGTCTGA

Upstream 100 bases:

>100_bases
GACGATGACAATTGGGCAGTTCAATGGCAAGTTTGCAGTCGTTCCGAGAGCATGGCACCGGCGCTGCATTGCTACTAAAA
CCCCGACAAGGAGAAAGATC

Downstream 100 bases:

>100_bases
CAGAAAATGCACCTCCGGGCAACCACAATCGAACGACCGAAGACGAGCCGGTATCGTCGGATTGTTGAGTGTCCACCCTG
CGGGAGGGTTACTATCGAGT

Product: protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MADLSRLRVAVLATDGFEETELTEPMRALQQAGAHVEIIAPAAGEIQAFRHHDKSVRVAVDRTLNEAQPNQYDALVLPGG
TFNADALRVDPKVQAFVRNMHQSGKPIAAICHAPWILISTGLVKGRTLTSYHTLQDDVRNAGGRWQDREVIVEGNWVTSR
KPDDLPAFNRELLNQLSALPGRV

Sequences:

>Translated_183_residues
MADLSRLRVAVLATDGFEETELTEPMRALQQAGAHVEIIAPAAGEIQAFRHHDKSVRVAVDRTLNEAQPNQYDALVLPGG
TFNADALRVDPKVQAFVRNMHQSGKPIAAICHAPWILISTGLVKGRTLTSYHTLQDDVRNAGGRWQDREVIVEGNWVTSR
KPDDLPAFNRELLNQLSALPGRV
>Mature_182_residues
ADLSRLRVAVLATDGFEETELTEPMRALQQAGAHVEIIAPAAGEIQAFRHHDKSVRVAVDRTLNEAQPNQYDALVLPGGT
FNADALRVDPKVQAFVRNMHQSGKPIAAICHAPWILISTGLVKGRTLTSYHTLQDDVRNAGGRWQDREVIVEGNWVTSRK
PDDLPAFNRELLNQLSALPGRV

Specific function: Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=172, Percent_Identity=44.1860465116279, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87081736, Length=164, Percent_Identity=28.0487804878049, Blast_Score=62, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571932, Length=175, Percent_Identity=29.1428571428571, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24653499, Length=169, Percent_Identity=30.1775147928994, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20177; Mature: 20046

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLSRLRVAVLATDGFEETELTEPMRALQQAGAHVEIIAPAAGEIQAFRHHDKSVRVAV
CCCHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEE
DRTLNEAQPNQYDALVLPGGTFNADALRVDPKVQAFVRNMHQSGKPIAAICHAPWILIST
ECHHCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEHHCCCEEEEEC
GLVKGRTLTSYHTLQDDVRNAGGRWQDREVIVEGNWVTSRKPDDLPAFNRELLNQLSALP
CCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCCCCCCHHHHHHHHHHHHCC
GRV
CCC
>Mature Secondary Structure 
ADLSRLRVAVLATDGFEETELTEPMRALQQAGAHVEIIAPAAGEIQAFRHHDKSVRVAV
CCHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHCCCEEEEEE
DRTLNEAQPNQYDALVLPGGTFNADALRVDPKVQAFVRNMHQSGKPIAAICHAPWILIST
ECHHCCCCCCCCCEEEECCCCCCCCEEEECHHHHHHHHHHHHCCCCEEEHHCCCEEEEEC
GLVKGRTLTSYHTLQDDVRNAGGRWQDREVIVEGNWVTSRKPDDLPAFNRELLNQLSALP
CCCCCCEEHHHHHHHHHHHHCCCCCCCCEEEEECCEECCCCCCCCCHHHHHHHHHHHHCC
GRV
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377; 10568751 [H]