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The map label for this gene is trpD

Identifier: 37522364

GI number: 37522364

Start: 2973462

End: 2974490

Strand: Reverse

Name: trpD

Synonym: gvip385

Alternate gene names: 37522364

Gene position: 2974490-2973462 (Counterclockwise)

Preceding gene: 37522365

Following gene: 37522362

Centisome position: 63.84

GC content: 68.51

Gene sequence:

>1029_bases
GTGATGAACGAAAAACATTTGCAGTCGTTGCTAATTTGTCGCCTGGGCGGCGCGGCGCTCTCGGAGGAAGCGGCCCGGGA
ACTGATGGAAGCGTGGCTGGCAGGGGAGGTGCCTGCCGCTCTCTCCGGTGCTCTGCTGGTGGCGATTGCGCCTTTGGCGA
TCACTGCAGGCGAACTGGCGGCGATGGCCAAGACGCTGCAAGAAGCTGCGGGCGCCGCCCCCACCGGGCTGCCGGTGCTG
CTCGACACCTGCGGCACCGGCGGGGACGGGCTGGGAACATTTAATATCTCGACGGCAGTCGCCTTTGTGGCGGCGGCCTG
CGGGGTACCCGTGGCCAAGCACGGTGCTCGCTCCGCCTCCAGCCGGGTCGGTTCGGCCGATGTGCTGGAGCACCTGGGAG
TGCACCTCAGCCAGGAGCGCGCGCGCGTGCGCGCCGCCCTCGACGCGGTGGGGATCACCTTTTTGTTCGCCCCGGGCTGG
CACCCGGCCTTAAAAGCCGTGGCACCCGTGCGCCGCGAACTGGGCATTCGTACAGTCTTCAATTTGCTCGGTCCCCTGGT
CAATCCACTGGTGCCCACCGCCCAGGTGCTCGGGGTTTACCATCCGAGTCTGGTTGCGCCGATGGCCGAAGCGCTGGAAC
GGTTGGGCCGCGAGCGCTTCCTGGTTGTCCACGGCGGCGGGGGGCTCGACGAGTGCTCGCTCACGGGACCAACCGCCCTG
GCGGGGAATCTGAGCGGTCCCATCTGCGGATCGCGCCTGCATCCCGAAGAACTGGGCCTGGCTGCCGCCCCGTTGGAAGC
ACTCGCCGGGGGGGATGTGGCAGAAAACGCCGACATCCTGCGCCGGGTGCTCCAGGGCAAAGGCAGCCGCGCCCAGAGCG
AAGTGGTTATCCTCAACACCGCCGCCGCCCTGGTGGCCGCCGGTGCGGCGGCAGGCTGGATGGCCGGGGTAACCCTGGCC
CGCGACTGTCTGGCGGACGGCGCTCCCTGGGCCAAGTGCGAGGCGCTTATCCGCTTCGGCAATACCTGA

Upstream 100 bases:

>100_bases
GTGTCGAAGGCCCCGTGCTCGAGGCCGACTTTGGACGCAACACCGTGCGCGCCAGCGGCGGCCGGGTGGTGACACGCGTC
CTGCCCGAAGTGATTCAAAA

Downstream 100 bases:

>100_bases
AGGCTCGGCCGGTGCGCCGCAAAATGACTCGCCCCTTGGTCAGTGCCGCCCGTCAGGGTTGGTCCGGATCGACGCCGAGG
GCGCGCAGGCGCTCCGTCAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELAAMAKTLQEAAGAAPTGLPVL
LDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSASSRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGW
HPALKAVAPVRRELGIRTVFNLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTAL
AGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNTAAALVAAGAAAGWMAGVTLA
RDCLADGAPWAKCEALIRFGNT

Sequences:

>Translated_342_residues
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELAAMAKTLQEAAGAAPTGLPVL
LDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSASSRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGW
HPALKAVAPVRRELGIRTVFNLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTAL
AGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNTAAALVAAGAAAGWMAGVTLA
RDCLADGAPWAKCEALIRFGNT
>Mature_342_residues
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELAAMAKTLQEAAGAAPTGLPVL
LDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSASSRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGW
HPALKAVAPVRRELGIRTVFNLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTAL
AGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNTAAALVAAGAAAGWMAGVTLA
RDCLADGAPWAKCEALIRFGNT

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=283, Percent_Identity=44.8763250883392, Blast_Score=208, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320561, Length=279, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_GLOVI (Q7NGU2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925741.1
- ProteinModelPortal:   Q7NGU2
- SMR:   Q7NGU2
- GeneID:   2601196
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.2795
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- BioCyc:   GVIO251221:GLL2795-MONOMER
- BRENDA:   2.4.2.18
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34654; Mature: 34654

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AMAKTLQEAAGAAPTGLPVLLDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSAS
HHHHHHHHHHCCCCCCCHHHEECCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHCCHHHH
SRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGWHPALKAVAPVRRELGIRTVF
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
NLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTAL
HHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHH
AGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNT
CCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEH
AAALVAAGAAAGWMAGVTLARDCLADGAPWAKCEALIRFGNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MMNEKHLQSLLICRLGGAALSEEAARELMEAWLAGEVPAALSGALLVAIAPLAITAGELA
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AMAKTLQEAAGAAPTGLPVLLDTCGTGGDGLGTFNISTAVAFVAAACGVPVAKHGARSAS
HHHHHHHHHHCCCCCCCHHHEECCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHCCHHHH
SRVGSADVLEHLGVHLSQERARVRAALDAVGITFLFAPGWHPALKAVAPVRRELGIRTVF
HCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHH
NLLGPLVNPLVPTAQVLGVYHPSLVAPMAEALERLGRERFLVVHGGGGLDECSLTGPTAL
HHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHH
AGNLSGPICGSRLHPEELGLAAAPLEALAGGDVAENADILRRVLQGKGSRAQSEVVILNT
CCCCCCCCCCCCCCHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEH
AAALVAAGAAAGWMAGVTLARDCLADGAPWAKCEALIRFGNT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14621292