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The map label for this gene is prpC [H]

Identifier: 37522326

GI number: 37522326

Start: 2935256

End: 2937412

Strand: Reverse

Name: prpC [H]

Synonym: gll2757

Alternate gene names: 37522326

Gene position: 2937412-2935256 (Counterclockwise)

Preceding gene: 37522329

Following gene: 37522325

Centisome position: 63.05

GC content: 67.41

Gene sequence:

>2157_bases
ATGTACTACCTCGCCATCGGTAACCCGCAGAAGCTGGCCACGCCTCTGGCCGAGCGCTACCAGCAGGTTCCCGCCGGTTT
GCTGCCGGTGGTGCGAGATCTCTCGCCGCACCAACCGCATCCGAGCCGCGAGGAACTGCCCGCCGCGGGCCGCCCTTACC
AGCGGCTCAACGACTGGCGCTGGGCGGTACCGGAGGTGTTTACCTTTTTGGAAGGTGCCGGGGAGCCCTGCCTGCTGTTG
AGCAACGCACCCCTCGACGATGACGGAGTGCCCTGGGGCCATCTGGCCGAGCACTGGCCGCAGGCAAGCGCTCTGCAGCA
ATTGGGTTGGCTTTCACAGATCGCCAAACTCTGGGATCCGTGTGTCGAGCAAAAGGTGGCTTCGTCGCTGCTGTTGCCCG
CCAACATCGGGGTGCAGGGCTGGCAAATGCGGCTGTTCTACCTTAAGGCCGACGCCGATGCCCCTACCCTGCGGCAGCTG
GCCGCTTGCTGGCGTACCCTCTCACCCTTGAGCGCGCCGCTCGCCTCCCTCGTCGGTGCCGTCGAGGCGGGCCAGGTGAG
CCGGGCGGCGGATCTCGTCGAAGCGCTCGAATCGATGGCGCTCCTCACGGCCACCGGCCGGGTGACCCAGATGAGCGCCG
CCACCGATGTCGGTCGGCGCCGCAAGAACAATGAAGATTGCTTTGCCCACGATCCTGCCGGGCGCTACGCGGTGGTCTGC
GACGGCATGGGCGGCCACGAGGGCGGTGAGGTGGCCAGCCGCATGGCCACCGAGAGCCTCGAGAGAGACCTGGGTGCGCT
GGCCGGTCAGGGTTTGACGCCCCGCGAGATCCGCTCCCGCCTGGCGGAGGCGCTCGGCAAAGCCAACGCCCGGCTCTGGG
AAACCAACCAACAGCAGCGGCGCAACGGCACCGGCCGCATGGGCACCACGGTGGTGGCTTGCTACCAGGACGGTGCACTA
CTGCATGTCGCCCACGTGGGCGACAGCCGCATCTATCTGGTGAATCGCAAGCACTGCCAGCAGATCACTGTCGATCACGA
CCTCACCCAAAAAGAAATTTCCCGCGCCCGCACCACCAGCGCCGCCGCCGCCCTCATCCCTACAGGCGGCACCCTCACCC
AGGCCCTGGGTTTGATGCCGGAAGGAACACTCCAACCGATGGTCCAGAGCTTTATCCTGCCTGAGGAGTGTCTGGTGCTG
CTCTGCAGCGACGGCCTGTGCGACGGCGATCTGGTGGAGCGCTCCTGGAAGAGCGCCCTCAGGCCGCTACTCGATCGCGA
TCTGGCCCCGGCGGCCCCGGCCCTTATCGATCTGGCTCTGCGCGAACTGGGGCACGACAACATCACTTTTGTGCTTCTGC
GCTACATGCCGGGGGCTGCCCGCGCCGCCGATTCGCCGCCCACCATTCCCCAGCGGCCCCGGCCGCAGACCCAGCAGATC
CCCGCCGCCGTGGTCGATGCCGCGGCGGCCAGGGCGGCCACGGCCAGCTCGATTCCGGCTGCCCGTCCCACTCCGCCCAC
CGGACGCAACCCCTGGCTTCCCATCGCTGCTGTGGCAGGGATTATAGCGGTGGCCGCAGGCGCCTACCTGTTGCTTCCCC
AGCCCGCCGTCCGCCGCGAAGCACCCACCTCCACCACGGAAAATTCCGCCGTCCGCCCGGTGCCCGTACCCGAGACGAGT
ACGCCCCCACCGACACTCCCTGCCGCGAGCGTTCCTGCCAAAACGCAGGCTGCGGCCGTCGCCGCTCCCCGGCCTACCGG
CGGCCCGGCTCCCAAACCTGCAAAGCCGGGCCTCACCACGCCCCCACCGCCTCCGGCAACCAATCCCGAGACTAGAGTTC
CTGAACAAATGCAGGGGCAAACCCGGCTCCCGCCCGATGCAAAAAAATCCGGTATCGTCGAGCAAGCCGACGGGCAACCG
GAGACCAAAGCGTCCGCGCGCAAGAAGCGGCGGGCGCGCAAACTCCAAGAGGAGAACAATTCCGGCGGTCTGGTGTTGCC
CAAGGCTTCCGTCGGTGCGCAACCGGAAGCGACGACTGTGGCTGACAAGATTGCTCCCCAACCGCCCATCCTGGAGCGCT
CTCTAATCGCCCCGCCCGTGCAACCGACGCGCAGCGAACCGGTTCTGCTCCCACCCAACACTTCAAGCACGCCATAG

Upstream 100 bases:

>100_bases
TGCACCCGCCCGCCCGCGACGACTAGGATGTGCAGTGCAAGACGGTATCTATCCCTAGCTGCCGGACATAGCTGTCGAGC
CGTGCCCAGAGAGCCTCTTT

Downstream 100 bases:

>100_bases
ACCGGGTGTCCATCGCATCGGTACCGCGGTGCAGAGGACGATAGGCCATGCACTACACTGGTAGATACGAGAATTCTTGA
CAGAATACTCGTAAACTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MYYLAIGNPQKLATPLAERYQQVPAGLLPVVRDLSPHQPHPSREELPAAGRPYQRLNDWRWAVPEVFTFLEGAGEPCLLL
SNAPLDDDGVPWGHLAEHWPQASALQQLGWLSQIAKLWDPCVEQKVASSLLLPANIGVQGWQMRLFYLKADADAPTLRQL
AACWRTLSPLSAPLASLVGAVEAGQVSRAADLVEALESMALLTATGRVTQMSAATDVGRRRKNNEDCFAHDPAGRYAVVC
DGMGGHEGGEVASRMATESLERDLGALAGQGLTPREIRSRLAEALGKANARLWETNQQQRRNGTGRMGTTVVACYQDGAL
LHVAHVGDSRIYLVNRKHCQQITVDHDLTQKEISRARTTSAAAALIPTGGTLTQALGLMPEGTLQPMVQSFILPEECLVL
LCSDGLCDGDLVERSWKSALRPLLDRDLAPAAPALIDLALRELGHDNITFVLLRYMPGAARAADSPPTIPQRPRPQTQQI
PAAVVDAAAARAATASSIPAARPTPPTGRNPWLPIAAVAGIIAVAAGAYLLLPQPAVRREAPTSTTENSAVRPVPVPETS
TPPPTLPAASVPAKTQAAAVAAPRPTGGPAPKPAKPGLTTPPPPPATNPETRVPEQMQGQTRLPPDAKKSGIVEQADGQP
ETKASARKKRRARKLQEENNSGGLVLPKASVGAQPEATTVADKIAPQPPILERSLIAPPVQPTRSEPVLLPPNTSSTP

Sequences:

>Translated_718_residues
MYYLAIGNPQKLATPLAERYQQVPAGLLPVVRDLSPHQPHPSREELPAAGRPYQRLNDWRWAVPEVFTFLEGAGEPCLLL
SNAPLDDDGVPWGHLAEHWPQASALQQLGWLSQIAKLWDPCVEQKVASSLLLPANIGVQGWQMRLFYLKADADAPTLRQL
AACWRTLSPLSAPLASLVGAVEAGQVSRAADLVEALESMALLTATGRVTQMSAATDVGRRRKNNEDCFAHDPAGRYAVVC
DGMGGHEGGEVASRMATESLERDLGALAGQGLTPREIRSRLAEALGKANARLWETNQQQRRNGTGRMGTTVVACYQDGAL
LHVAHVGDSRIYLVNRKHCQQITVDHDLTQKEISRARTTSAAAALIPTGGTLTQALGLMPEGTLQPMVQSFILPEECLVL
LCSDGLCDGDLVERSWKSALRPLLDRDLAPAAPALIDLALRELGHDNITFVLLRYMPGAARAADSPPTIPQRPRPQTQQI
PAAVVDAAAARAATASSIPAARPTPPTGRNPWLPIAAVAGIIAVAAGAYLLLPQPAVRREAPTSTTENSAVRPVPVPETS
TPPPTLPAASVPAKTQAAAVAAPRPTGGPAPKPAKPGLTTPPPPPATNPETRVPEQMQGQTRLPPDAKKSGIVEQADGQP
ETKASARKKRRARKLQEENNSGGLVLPKASVGAQPEATTVADKIAPQPPILERSLIAPPVQPTRSEPVLLPPNTSSTP
>Mature_718_residues
MYYLAIGNPQKLATPLAERYQQVPAGLLPVVRDLSPHQPHPSREELPAAGRPYQRLNDWRWAVPEVFTFLEGAGEPCLLL
SNAPLDDDGVPWGHLAEHWPQASALQQLGWLSQIAKLWDPCVEQKVASSLLLPANIGVQGWQMRLFYLKADADAPTLRQL
AACWRTLSPLSAPLASLVGAVEAGQVSRAADLVEALESMALLTATGRVTQMSAATDVGRRRKNNEDCFAHDPAGRYAVVC
DGMGGHEGGEVASRMATESLERDLGALAGQGLTPREIRSRLAEALGKANARLWETNQQQRRNGTGRMGTTVVACYQDGAL
LHVAHVGDSRIYLVNRKHCQQITVDHDLTQKEISRARTTSAAAALIPTGGTLTQALGLMPEGTLQPMVQSFILPEECLVL
LCSDGLCDGDLVERSWKSALRPLLDRDLAPAAPALIDLALRELGHDNITFVLLRYMPGAARAADSPPTIPQRPRPQTQQI
PAAVVDAAAARAATASSIPAARPTPPTGRNPWLPIAAVAGIIAVAAGAYLLLPQPAVRREAPTSTTENSAVRPVPVPETS
TPPPTLPAASVPAKTQAAAVAAPRPTGGPAPKPAKPGLTTPPPPPATNPETRVPEQMQGQTRLPPDAKKSGIVEQADGQP
ETKASARKKRRARKLQEENNSGGLVLPKASVGAQPEATTVADKIAPQPPILERSLIAPPVQPTRSEPVLLPPNTSSTP

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 76312; Mature: 76312

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYLAIGNPQKLATPLAERYQQVPAGLLPVVRDLSPHQPHPSREELPAAGRPYQRLNDWR
CEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHCHH
WAVPEVFTFLEGAGEPCLLLSNAPLDDDGVPWGHLAEHWPQASALQQLGWLSQIAKLWDP
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CVEQKVASSLLLPANIGVQGWQMRLFYLKADADAPTLRQLAACWRTLSPLSAPLASLVGA
HHHHHHHHHEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
VEAGQVSRAADLVEALESMALLTATGRVTQMSAATDVGRRRKNNEDCFAHDPAGRYAVVC
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEE
DGMGGHEGGEVASRMATESLERDLGALAGQGLTPREIRSRLAEALGKANARLWETNQQQR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHH
RNGTGRMGTTVVACYQDGALLHVAHVGDSRIYLVNRKHCQQITVDHDLTQKEISRARTTS
HCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEHHHHHEECCCCCHHHHHHHHHHHHH
AAAALIPTGGTLTQALGLMPEGTLQPMVQSFILPEECLVLLCSDGLCDGDLVERSWKSAL
HHEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RPLLDRDLAPAAPALIDLALRELGHDNITFVLLRYMPGAARAADSPPTIPQRPRPQTQQI
HHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEHEECCCCHHCCCCCCCCCCCCCCCCHHHC
PAAVVDAAAARAATASSIPAARPTPPTGRNPWLPIAAVAGIIAVAAGAYLLLPQPAVRRE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHCC
APTSTTENSAVRPVPVPETSTPPPTLPAASVPAKTQAAAVAAPRPTGGPAPKPAKPGLTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCC
PPPPPATNPETRVPEQMQGQTRLPPDAKKSGIVEQADGQPETKASARKKRRARKLQEENN
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SGGLVLPKASVGAQPEATTVADKIAPQPPILERSLIAPPVQPTRSEPVLLPPNTSSTP
CCCEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCCC
>Mature Secondary Structure
MYYLAIGNPQKLATPLAERYQQVPAGLLPVVRDLSPHQPHPSREELPAAGRPYQRLNDWR
CEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHHHCHH
WAVPEVFTFLEGAGEPCLLLSNAPLDDDGVPWGHLAEHWPQASALQQLGWLSQIAKLWDP
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
CVEQKVASSLLLPANIGVQGWQMRLFYLKADADAPTLRQLAACWRTLSPLSAPLASLVGA
HHHHHHHHHEECCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHH
VEAGQVSRAADLVEALESMALLTATGRVTQMSAATDVGRRRKNNEDCFAHDPAGRYAVVC
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEE
DGMGGHEGGEVASRMATESLERDLGALAGQGLTPREIRSRLAEALGKANARLWETNQQQR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEECCCHHHH
RNGTGRMGTTVVACYQDGALLHVAHVGDSRIYLVNRKHCQQITVDHDLTQKEISRARTTS
HCCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEHHHHHEECCCCCHHHHHHHHHHHHH
AAAALIPTGGTLTQALGLMPEGTLQPMVQSFILPEECLVLLCSDGLCDGDLVERSWKSAL
HHEEEECCCCHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
RPLLDRDLAPAAPALIDLALRELGHDNITFVLLRYMPGAARAADSPPTIPQRPRPQTQQI
HHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEHEECCCCHHCCCCCCCCCCCCCCCCHHHC
PAAVVDAAAARAATASSIPAARPTPPTGRNPWLPIAAVAGIIAVAAGAYLLLPQPAVRRE
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHCC
APTSTTENSAVRPVPVPETSTPPPTLPAASVPAKTQAAAVAAPRPTGGPAPKPAKPGLTT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCCCCC
PPPPPATNPETRVPEQMQGQTRLPPDAKKSGIVEQADGQPETKASARKKRRARKLQEENN
CCCCCCCCCCCCCCHHHCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
SGGLVLPKASVGAQPEATTVADKIAPQPPILERSLIAPPVQPTRSEPVLLPPNTSSTP
CCCEEEECCCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]